LLPS-Gor-2316
EIF6
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Eukaryotic translation initiation factor 6 |
| Gene Name: | EIF6, B456_009G309100 |
| Ensembl Gene: | B456_009G309100 |
| Ensembl Protein: | KJB60507 |
| Organism: | Gossypium raimondii |
| Taxa ID: | 29730 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, P-body | Predicted from orthologs | (View) |
▼ FUNCTION
| Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | KJB60507 | KJB60507 |
| Ensembl | KJB60506 | KJB60506 |
| Ensembl | KJB60504 | KJB60504 |
| Ensembl | KJB60505 | KJB60505 |
| UniProt | A0A0D2QRA2, A0A0D2QRA2_GOSRA | |
| GeneBank | CM001748 | KJB60507.1 |
| RefSeq | XM_012592197.1 | XP_012447651.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MATRLQFENS CEVGVFSKLT NAYCLVAIGG SENFYSAFES ELADVIPVIK TSLGGTRIIG 60 61 RLCAGNKNGL LVPHTTTDQE LQHLRNSLPD QVVVQRIEEK LSALGNCIAC NDHVALTHTD 120 121 LDRETEEIIA DVLGVEVFRQ TIAGNILVGS YCAFSNRGGL VHPHTSIEDL DELSTLLQVP 180 181 LVAGTINRGS EVIAAGMTVN DWTAFCGSDT TATELSVIES VFKLREAQPT AIVDEMRKSL 240 241 IDTYV 245 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCAACTA GGCTACAGTT TGAAAATTCA TGTGAAGTTG GAGTGTTTTC CAAGCTGACC 60 61 AATGCTTATT GCTTGGTTGC AATTGGAGGG TCTGAAAACT TCTACAGTGC TTTTGAGTCT 120 121 GAGTTAGCGG ATGTCATTCC TGTCATTAAG ACCTCTCTTG GCGGCACTAG AATAATAGGA 180 181 CGGCTCTGTG CTGGAAATAA GAATGGGCTT CTTGTCCCTC ACACCACCAC AGATCAAGAA 240 241 CTTCAACACT TGCGAAATAG TCTACCGGAT CAAGTTGTTG TTCAGCGCAT AGAGGAGAAA 300 301 CTATCTGCTC TTGGGAACTG TATAGCTTGC AATGACCATG TTGCTCTGAC GCATACAGAT 360 361 CTAGATCGGT TTTCAGGCAA ACAATTGCCG GAAATATTCT TGTTGGGAGC TACTGTGCAT 420 421 TTTCAAACCG AGGTGGCTTG GTTCATCCTC ACACATCCAT TGAAGACTTG GATGAGCTTT 480 481 CGACGCTTCT TCAGGTTCCA TTGGTGGCTG GCACCATCAA CCGTGGGAGT GAAGTAA 537 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Nucleolus | |
Molecular Function | Ribosomal large subunit binding | |
Molecular Function | Ribosome binding | |
Molecular Function | Translation initiation factor activity | |
Biological Process | Mature ribosome assembly | |
Biological Process | Ribosomal large subunit biogenesis |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Coc-2029 | Corchorus capsularis | 98.37 | 4e-178 | 497 |
| LLPS-Viv-0361 | Vitis vinifera | 94.69 | 1e-173 | 485 |
| LLPS-Glm-2615 | Glycine max | 94.69 | 2e-173 | 485 |
| LLPS-Via-0566 | Vigna angularis | 94.69 | 3e-174 | 487 |
| LLPS-Phv-0709 | Phaseolus vulgaris | 94.29 | 1e-174 | 488 |
| LLPS-Hea-0497 | Helianthus annuus | 94.29 | 3e-173 | 484 |
| LLPS-Bro-1910 | Brassica oleracea | 93.88 | 3e-173 | 484 |
| LLPS-Prp-0384 | Prunus persica | 93.88 | 1e-173 | 485 |
| LLPS-Nia-0795 | Nicotiana attenuata | 93.47 | 2e-171 | 480 |
| LLPS-Mae-0335 | Manihot esculenta | 93.47 | 3e-171 | 479 |
| LLPS-Pot-0485 | Populus trichocarpa | 93.47 | 4e-171 | 479 |
| LLPS-Brr-0575 | Brassica rapa | 93.47 | 2e-172 | 482 |
| LLPS-Thc-1176 | Theobroma cacao | 93.47 | 4e-171 | 479 |
| LLPS-Brn-0114 | Brassica napus | 93.47 | 2e-172 | 482 |
| LLPS-Dac-1449 | Daucus carota | 93.27 | 1e-143 | 408 |
| LLPS-Mua-0595 | Musa acuminata | 93.06 | 4e-171 | 479 |
| LLPS-Sol-0424 | Solanum lycopersicum | 92.24 | 6e-168 | 471 |
| LLPS-Arl-0556 | Arabidopsis lyrata | 92.24 | 7e-171 | 478 |
| LLPS-Sei-0047 | Setaria italica | 92.24 | 2e-168 | 472 |
| LLPS-Vir-0813 | Vigna radiata | 92.03 | 6e-171 | 479 |
| LLPS-Sob-0327 | Sorghum bicolor | 91.84 | 3e-169 | 474 |
| LLPS-Art-0635 | Arabidopsis thaliana | 91.84 | 8e-171 | 478 |
| LLPS-Tra-0068 | Triticum aestivum | 91.84 | 9e-169 | 473 |
| LLPS-Brd-0063 | Brachypodium distachyon | 91.84 | 1e-168 | 473 |
| LLPS-Sot-0968 | Solanum tuberosum | 91.84 | 3e-167 | 469 |
| LLPS-Hov-0643 | Hordeum vulgare | 91.7 | 2e-165 | 465 |
| LLPS-Orbr-0578 | Oryza brachyantha | 91.43 | 1e-168 | 473 |
| LLPS-Orp-0105 | Oryza punctata | 91.43 | 3e-168 | 471 |
| LLPS-Ors-0656 | Oryza sativa | 91.43 | 3e-168 | 471 |
| LLPS-Org-0365 | Oryza glaberrima | 91.43 | 3e-168 | 471 |
| LLPS-Zem-0444 | Zea mays | 91.43 | 8e-169 | 473 |
| LLPS-Orr-1507 | Oryza rufipogon | 91.43 | 3e-168 | 471 |
| LLPS-Orm-0202 | Oryza meridionalis | 91.43 | 3e-168 | 471 |
| LLPS-Orni-0294 | Oryza nivara | 91.43 | 3e-168 | 471 |
| LLPS-Ori-0424 | Oryza indica | 91.43 | 3e-168 | 471 |
| LLPS-Orb-0241 | Oryza barthii | 91.43 | 3e-168 | 471 |
| LLPS-Orgl-0599 | Oryza glumaepatula | 91.43 | 3e-168 | 471 |
| LLPS-Met-1424 | Medicago truncatula | 90.2 | 1e-166 | 468 |
| LLPS-Amt-0304 | Amborella trichopoda | 88.38 | 4e-158 | 447 |
| LLPS-Cus-0308 | Cucumis sativus | 87.35 | 3e-161 | 454 |
| LLPS-Lep-0036 | Leersia perrieri | 86.05 | 2e-163 | 460 |
| LLPS-Php-0070 | Physcomitrella patens | 83.13 | 1e-152 | 432 |
| LLPS-Sem-0867 | Selaginella moellendorffii | 81.89 | 2e-150 | 426 |
| LLPS-Tru-0785 | Triticum urartu | 77.37 | 1e-141 | 404 |
| LLPS-Chr-0685 | Chlamydomonas reinhardtii | 76.54 | 2e-140 | 401 |
| LLPS-Ict-0683 | Ictidomys tridecemlineatus | 75.43 | 3e-130 | 375 |
| LLPS-Gog-0605 | Gorilla gorilla | 75.43 | 2e-130 | 376 |
| LLPS-Anp-1184 | Anas platyrhynchos | 75.42 | 3e-97 | 289 |
| LLPS-Ora-0627 | Ornithorhynchus anatinus | 75.42 | 1e-95 | 286 |
| LLPS-Abg-0326 | Absidia glauca | 75.41 | 1e-137 | 394 |
| LLPS-Otg-0086 | Otolemur garnettii | 75.0 | 7e-136 | 390 |
| LLPS-Orl-2433 | Oryzias latipes | 75.0 | 2e-132 | 381 |
| LLPS-Bot-0634 | Bos taurus | 75.0 | 3e-129 | 373 |
| LLPS-Mum-0724 | Mus musculus | 74.9 | 1e-135 | 389 |
| LLPS-Ran-2316 | Rattus norvegicus | 74.79 | 9e-135 | 387 |
| LLPS-Cii-0521 | Ciona intestinalis | 74.69 | 4e-135 | 388 |
| LLPS-Asn-0338 | Aspergillus nidulans | 74.57 | 9e-123 | 356 |
| LLPS-Rhb-0534 | Rhinopithecus bieti | 74.49 | 3e-135 | 388 |
| LLPS-Man-0762 | Macaca nemestrina | 74.49 | 3e-135 | 388 |
| LLPS-Fec-0390 | Felis catus | 74.49 | 9e-135 | 387 |
| LLPS-Mod-1029 | Monodelphis domestica | 74.49 | 2e-135 | 388 |
| LLPS-Hos-1849 | Homo sapiens | 74.49 | 3e-135 | 388 |
| LLPS-Pat-0111 | Pan troglodytes | 74.49 | 3e-135 | 388 |
| LLPS-Pap-1605 | Pan paniscus | 74.49 | 3e-135 | 388 |
| LLPS-Anc-1012 | Anolis carolinensis | 74.49 | 1e-132 | 381 |
| LLPS-Nol-0777 | Nomascus leucogenys | 74.49 | 3e-135 | 388 |
| LLPS-Cas-1872 | Carlito syrichta | 74.49 | 5e-134 | 386 |
| LLPS-Eqc-0180 | Equus caballus | 74.49 | 8e-135 | 387 |
| LLPS-Sus-0781 | Sus scrofa | 74.49 | 1e-134 | 386 |
| LLPS-Chs-0426 | Chlorocebus sabaeus | 74.49 | 3e-135 | 388 |
| LLPS-Maf-0199 | Macaca fascicularis | 74.49 | 3e-135 | 388 |
| LLPS-Mal-0272 | Mandrillus leucophaeus | 74.49 | 3e-135 | 388 |
| LLPS-Caf-0140 | Canis familiaris | 74.38 | 4e-133 | 382 |
| LLPS-Cap-0898 | Cavia porcellus | 74.29 | 2e-135 | 389 |
| LLPS-Cea-0461 | Cercocebus atys | 74.29 | 3e-135 | 389 |
| LLPS-Aim-1446 | Ailuropoda melanoleuca | 74.29 | 1e-134 | 386 |
| LLPS-Paa-2362 | Papio anubis | 74.29 | 3e-135 | 389 |
| LLPS-Fud-2304 | Fukomys damarensis | 74.18 | 1e-134 | 387 |
| LLPS-Urm-2394 | Ursus maritimus | 74.07 | 2e-133 | 384 |
| LLPS-Leo-2208 | Lepisosteus oculatus | 74.07 | 3e-133 | 383 |
| LLPS-Mup-0576 | Mustela putorius furo | 74.07 | 2e-133 | 384 |
| LLPS-Scf-0269 | Scleropages formosus | 74.07 | 2e-133 | 383 |
| LLPS-Tut-1153 | Tursiops truncatus | 74.07 | 6e-134 | 385 |
| LLPS-Tar-1861 | Takifugu rubripes | 73.98 | 4e-130 | 381 |
| LLPS-Loa-0986 | Loxodonta africana | 73.88 | 2e-134 | 386 |
| LLPS-Caj-0749 | Callithrix jacchus | 73.88 | 2e-135 | 390 |
| LLPS-Aon-1324 | Aotus nancymaae | 73.88 | 2e-135 | 390 |
| LLPS-Myl-0520 | Myotis lucifugus | 73.88 | 7e-135 | 387 |
| LLPS-Ova-0658 | Ovis aries | 73.88 | 1e-134 | 387 |
| LLPS-Orn-1352 | Oreochromis niloticus | 73.77 | 3e-130 | 375 |
| LLPS-Pof-0157 | Poecilia formosa | 73.77 | 2e-131 | 378 |
| LLPS-Xim-1374 | Xiphophorus maculatus | 73.77 | 2e-131 | 378 |
| LLPS-Meg-0111 | Meleagris gallopavo | 73.66 | 1e-131 | 379 |
| LLPS-Dar-0303 | Danio rerio | 73.66 | 3e-131 | 378 |
| LLPS-Gaga-1911 | Gallus gallus | 73.66 | 9e-132 | 379 |
| LLPS-Poa-0115 | Pongo abelii | 73.66 | 3e-134 | 385 |
| LLPS-Dio-0383 | Dipodomys ordii | 73.66 | 2e-134 | 386 |
| LLPS-Tag-0027 | Taeniopygia guttata | 73.55 | 3e-131 | 377 |
| LLPS-Asg-0086 | Ashbya gossypii | 73.36 | 7e-132 | 379 |
| LLPS-Pes-0118 | Pelodiscus sinensis | 73.33 | 6e-112 | 328 |
| LLPS-Asf-0994 | Aspergillus flavus | 73.28 | 2e-122 | 355 |
| LLPS-Orc-0484 | Oryctolagus cuniculus | 73.25 | 1e-132 | 382 |
| LLPS-Fia-0063 | Ficedula albicollis | 73.25 | 5e-129 | 372 |
| LLPS-Icp-0248 | Ictalurus punctatus | 73.25 | 1e-131 | 379 |
| LLPS-Asm-0744 | Astyanax mexicanus | 73.25 | 2e-131 | 378 |
| LLPS-Mea-1234 | Mesocricetus auratus | 73.25 | 7e-133 | 382 |
| LLPS-Sah-0864 | Sarcophilus harrisii | 73.21 | 1e-111 | 327 |
| LLPS-Crn-0755 | Cryptococcus neoformans | 72.95 | 3e-132 | 380 |
| LLPS-Cis-0060 | Ciona savignyi | 72.76 | 2e-131 | 378 |
| LLPS-Scm-1936 | Scophthalmus maximus | 72.54 | 5e-130 | 375 |
| LLPS-Sac-0417 | Saccharomyces cerevisiae | 72.54 | 5e-133 | 382 |
| LLPS-Chc-0415 | Chondrus crispus | 72.31 | 1e-130 | 376 |
| LLPS-Kop-0526 | Komagataella pastoris | 72.13 | 1e-132 | 382 |
| LLPS-Asc-0258 | Aspergillus clavatus | 71.98 | 2e-121 | 353 |
| LLPS-Drm-0881 | Drosophila melanogaster | 71.9 | 1e-128 | 371 |
| LLPS-Spr-0089 | Sporisorium reilianum | 71.84 | 2e-128 | 370 |
| LLPS-Ten-1449 | Tetraodon nigroviridis | 71.77 | 9e-127 | 367 |
| LLPS-Xet-2828 | Xenopus tropicalis | 71.43 | 2e-66 | 209 |
| LLPS-Nec-0697 | Neurospora crassa | 71.43 | 2e-125 | 363 |
| LLPS-Scc-0030 | Schizosaccharomyces cryophilus | 71.31 | 1e-129 | 374 |
| LLPS-Scp-0453 | Schizosaccharomyces pombe | 71.31 | 2e-128 | 371 |
| LLPS-Usm-0777 | Ustilago maydis | 71.02 | 2e-127 | 368 |
| LLPS-Scs-0132 | Sclerotinia sclerotiorum | 71.02 | 8e-126 | 364 |
| LLPS-Gaa-1213 | Gasterosteus aculeatus | 71.02 | 4e-129 | 372 |
| LLPS-Ast-0261 | Aspergillus terreus | 70.9 | 7e-125 | 362 |
| LLPS-Trr-0760 | Trichoderma reesei | 70.61 | 5e-128 | 370 |
| LLPS-Miv-0408 | Microbotryum violaceum | 70.61 | 7e-123 | 357 |
| LLPS-Map-0024 | Magnaporthe poae | 70.61 | 3e-125 | 363 |
| LLPS-Gag-0108 | Gaeumannomyces graminis | 70.61 | 1e-125 | 363 |
| LLPS-Fus-0429 | Fusarium solani | 70.2 | 1e-126 | 366 |
| LLPS-Fuo-0638 | Fusarium oxysporum | 70.2 | 7e-127 | 367 |
| LLPS-Mao-0265 | Magnaporthe oryzae | 70.2 | 1e-124 | 361 |
| LLPS-Fuv-0047 | Fusarium verticillioides | 70.2 | 7e-127 | 367 |
| LLPS-Tum-0158 | Tuber melanosporum | 70.2 | 3e-124 | 360 |
| LLPS-Yal-0649 | Yarrowia lipolytica | 70.18 | 7e-120 | 349 |
| LLPS-Gas-0577 | Galdieria sulphuraria | 69.96 | 2e-121 | 353 |
| LLPS-Lac-0271 | Latimeria chalumnae | 69.92 | 5e-59 | 190 |
| LLPS-Asni-0753 | Aspergillus niger | 69.92 | 2e-123 | 358 |
| LLPS-Beb-0927 | Beauveria bassiana | 69.8 | 7e-125 | 362 |
| LLPS-Pug-0185 | Puccinia graminis | 69.8 | 2e-121 | 353 |
| LLPS-Put-0362 | Puccinia triticina | 69.8 | 2e-121 | 353 |
| LLPS-Pytr-0123 | Pyrenophora triticirepentis | 69.8 | 2e-123 | 358 |
| LLPS-Trv-0090 | Trichoderma virens | 69.8 | 6e-127 | 367 |
| LLPS-Coo-1347 | Colletotrichum orbiculare | 69.8 | 6e-125 | 362 |
| LLPS-Zyt-0121 | Zymoseptoria tritici | 69.8 | 4e-122 | 355 |
| LLPS-Pyt-0792 | Pyrenophora teres | 69.8 | 2e-123 | 358 |
| LLPS-Lem-0256 | Leptosphaeria maculans | 69.8 | 2e-123 | 358 |
| LLPS-Osl-0024 | Ostreococcus lucimarinus | 69.49 | 3e-124 | 360 |
| LLPS-Cog-0127 | Colletotrichum gloeosporioides | 69.39 | 1e-124 | 361 |
| LLPS-Phn-0338 | Phaeosphaeria nodorum | 69.39 | 1e-122 | 356 |
| LLPS-Dos-0400 | Dothistroma septosporum | 69.39 | 1e-122 | 356 |
| LLPS-Nef-0072 | Neosartorya fischeri | 69.11 | 3e-122 | 355 |
| LLPS-Asfu-0241 | Aspergillus fumigatus | 69.11 | 3e-122 | 355 |
| LLPS-Ved-1191 | Verticillium dahliae | 68.98 | 8e-123 | 357 |
| LLPS-Scj-0528 | Schizosaccharomyces japonicus | 68.85 | 1e-125 | 363 |
| LLPS-Cym-0025 | Cyanidioschyzon merolae | 68.57 | 9e-121 | 351 |
| LLPS-Blg-1094 | Blumeria graminis | 68.16 | 4e-121 | 352 |
| LLPS-Cogr-0832 | Colletotrichum graminicola | 67.76 | 2e-120 | 350 |
| LLPS-Aso-0233 | Aspergillus oryzae | 65.76 | 1e-115 | 339 |
| LLPS-Mel-0000 | Melampsora laricipopulina | 64.04 | 4e-117 | 343 |
| LLPS-Cae-0001 | Caenorhabditis elegans | 59.35 | 5e-105 | 311 |
| LLPS-Mam-1133 | Macaca mulatta | 55.78 | 4e-80 | 247 |