DrLLPS - Data resource of LLPS

LLPS-Glm-0700
100790892

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	U1 small nuclear ribonucleoprotein C
Gene Name:	100790892, GLYMA_10G021900
Ensembl Gene:	GLYMA_10G021900
Ensembl Protein:	KRH31930
Organism:	Glycine max
Taxa ID:	3847
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nuclear speckle, Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Mus musculus	LLPS-Mum-0964	Q62241	Client	Nuclear speckle, Nucleolus	82.03	0.0	692
Homo sapiens	LLPS-Hos-0959	P09234	Client	Nucleolus	64.52	6e-19	85.1

▼ FUNCTION

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	KRH31930	KRH31930
Ensembl	KRH31933	KRH31933
Ensembl	KRH31931	KRH31931
Ensembl	KRH31932	KRH31932
UniProt		A0A0R0HN81, A0A0R0HN81_SOYBN
GeneBank	CM000843	KRH31930.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MPRYYCDYCD TYLTHDSPSV RKQHNAGYKH KANVRTYYQQ FEEQQTQSLI DQRIKEHLGQ 60 61 AAAFQQVGVA YNHLMVQRPN LPPVLPPPRL PIPGNAQIPG GQPLMQGMRP PVFPRPPGAP 120 121 GYVSAHTMPP MLPPPGAPQV PGQLNTIPRP PSLAPPPTVP GSTATPASNG APSMVSSAMY 180 181 QANPPAPSSG SYDNYNTSAQ APEVHSA 207
Nucleotide CDS Sequence (FASTA)
1 ATGCCTCGGT ACTACTGTGA CTACTGCGAC ACCTATTTGA CCCACGATTC TCCATCTGTT 60 61 AGAAAGCAGC ACAATGCAGG TTACAAACAC AAGGCAAATG TGAGGACTTA CTACCAGCAA 120 121 TTTGAAGAAC AACAAACACA AAGTTTAATT GATCAAAGGA TCAAAGAACA TCTTGGGCAA 180 181 GCTGCTGCAT TTCAGCAAGT TGGTGTGGCT TATAATCATC TAATGGTTCA GAGGCCTAAC 240 241 CTTCCTCCTG TATTGCCACC ACCAAGATTG CCTATTCCTG GAAATGCACA AATACCTGGA 300 301 GGCCAACCAC TAATGCAAGG GATGAGACCA CCTGTCTTTC CTAGACCTCC TGGTGCACCA 360 361 GGATATGTTT CTGCACATAC CATGCCTCCG ATGTTACCTC CACCTGGTGC TCCCCAGGTT 420 421 CCAGGTCAAC TAAATACCAT ACCAAGGCCC CCTTCATTAG CTCCCCCTCC AACGGTTCCT 480 481 GGAAGCACTG CTACACCAGC TTCCAATGGT GCTCCCTCTA TGGTATCATC AGCAATGTAT 540 541 CAAGCCAATC CTCCGGCACC TTCATCTGGA AGTTATGATA ACTACAATAC GAGTGCTCAA 600 601 GCACCTGAGG TTCACTCTGC ATAA 624

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0479	Metal-binding
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0687	Ribonucleoprotein
KW-0694	RNA-binding
KW-0862	Zinc
KW-0863	Zinc-finger

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0000243	Cellular Component	Commitment complex
GO:0005685	Cellular Component	U1 snRNP
GO:0071004	Cellular Component	U2-type prespliceosome
GO:0003729	Molecular Function	MRNA binding
GO:0030619	Molecular Function	U1 snRNA binding
GO:0008270	Molecular Function	Zinc ion binding
GO:0000395	Biological Process	MRNA 5'-splice site recognition
GO:0000387	Biological Process	Spliceosomal snRNP assembly

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Sob-1169	Sorghum bicolor	100.0	9e-25	102
LLPS-Zem-1165	Zea mays	100.0	8e-25	103
LLPS-Mua-1515	Musa acuminata	98.28	4e-25	102
LLPS-Brd-1941	Brachypodium distachyon	96.55	1e-24	101
LLPS-Amt-1071	Amborella trichopoda	94.83	1e-24	101
LLPS-Sem-1552	Selaginella moellendorffii	92.59	2e-19	91.3
LLPS-Cus-0351	Cucumis sativus	92.41	1e-26	106
LLPS-Php-2491	Physcomitrella patens	91.38	1e-21	93.6
LLPS-Vir-0305	Vigna radiata	90.37	1e-45	157
LLPS-Brn-3365	Brassica napus	89.47	3e-25	102
LLPS-Orp-0902	Oryza punctata	89.33	5e-25	103
LLPS-Ors-1881	Oryza sativa	89.33	4e-25	103
LLPS-Org-0717	Oryza glaberrima	89.33	4e-25	103
LLPS-Orr-0987	Oryza rufipogon	89.33	3e-25	103
LLPS-Orni-0671	Oryza nivara	89.33	4e-25	103
LLPS-Orb-0033	Oryza barthii	89.33	4e-25	103
LLPS-Ori-0787	Oryza indica	89.33	5e-25	103
LLPS-Sei-1841	Setaria italica	89.33	7e-25	102
LLPS-Lep-1288	Leersia perrieri	89.33	6e-25	102
LLPS-Orgl-0942	Oryza glumaepatula	89.33	4e-25	103
LLPS-Via-0252	Vigna angularis	88.73	6e-56	183
LLPS-Phv-1032	Phaseolus vulgaris	88.67	1e-61	197
LLPS-Chr-1297	Chlamydomonas reinhardtii	88.57	8e-15	74.3
LLPS-Brr-1093	Brassica rapa	88.16	1e-24	100
LLPS-Bro-0756	Brassica oleracea	88.16	1e-24	101
LLPS-Tra-2955	Triticum aestivum	88.0	1e-24	102
LLPS-Art-2677	Arabidopsis thaliana	85.53	1e-24	101
LLPS-Arl-0319	Arabidopsis lyrata	81.58	4e-24	99.8
LLPS-Hov-0433	Hordeum vulgare	78.18	2e-12	67.8
LLPS-Osl-0211	Ostreococcus lucimarinus	77.14	6e-14	68.2
LLPS-Met-2587	Medicago truncatula	74.29	3e-41	145
LLPS-Mod-2971	Monodelphis domestica	73.08	2e-14	72.0
LLPS-Sah-2419	Sarcophilus harrisii	73.08	2e-14	72.0
LLPS-Otg-3029	Otolemur garnettii	72.92	1e-11	64.3
LLPS-Nol-0102	Nomascus leucogenys	72.92	1e-11	64.3
LLPS-Pes-0245	Pelodiscus sinensis	72.0	3e-13	69.3
LLPS-Gaa-0599	Gasterosteus aculeatus	72.0	4e-13	68.2
LLPS-Scf-2731	Scleropages formosus	72.0	1e-12	67.8
LLPS-Meg-0907	Meleagris gallopavo	71.43	3e-12	66.2
LLPS-Orl-1191	Oryzias latipes	71.43	1e-12	67.8
LLPS-Mum-0964	Mus musculus	71.43	2e-12	66.6
LLPS-Dio-0824	Dipodomys ordii	71.43	6e-12	65.1
LLPS-Fia-2645	Ficedula albicollis	71.15	4e-14	71.2
LLPS-Orc-2707	Oryctolagus cuniculus	71.15	5e-14	71.2
LLPS-Rhb-2018	Rhinopithecus bieti	71.15	3e-14	71.6
LLPS-Orn-0178	Oreochromis niloticus	71.15	4e-14	70.9
LLPS-Loa-0554	Loxodonta africana	71.15	4e-14	71.2
LLPS-Urm-0872	Ursus maritimus	71.15	4e-14	71.6
LLPS-Pap-1080	Pan paniscus	71.15	4e-14	71.2
LLPS-Pat-0788	Pan troglodytes	71.15	4e-14	71.2
LLPS-Pof-0303	Poecilia formosa	71.15	3e-14	71.2
LLPS-Dar-3281	Danio rerio	71.15	6e-14	70.9
LLPS-Lac-0427	Latimeria chalumnae	71.15	4e-14	71.6
LLPS-Scm-2692	Scophthalmus maximus	71.15	3e-14	71.2
LLPS-Ict-1398	Ictidomys tridecemlineatus	71.15	4e-14	71.2
LLPS-Tag-2652	Taeniopygia guttata	71.15	6e-14	70.9
LLPS-Cas-1016	Carlito syrichta	71.15	4e-14	71.2
LLPS-Xet-0099	Xenopus tropicalis	71.15	4e-14	71.2
LLPS-Ten-0032	Tetraodon nigroviridis	71.15	5e-14	71.2
LLPS-Caf-1882	Canis familiaris	71.15	4e-14	71.6
LLPS-Poa-4533	Pongo abelii	71.15	9e-15	72.0
LLPS-Eqc-2252	Equus caballus	71.15	5e-14	71.2
LLPS-Cap-0529	Cavia porcellus	71.15	4e-14	71.2
LLPS-Asm-1099	Astyanax mexicanus	71.15	8e-14	70.9
LLPS-Fud-1400	Fukomys damarensis	71.15	4e-14	71.2
LLPS-Cae-0213	Caenorhabditis elegans	71.15	2e-15	75.1
LLPS-Icp-0909	Ictalurus punctatus	71.15	5e-14	71.2
LLPS-Caj-3838	Callithrix jacchus	71.15	4e-14	71.2
LLPS-Gog-2228	Gorilla gorilla	71.15	4e-14	71.2
LLPS-Aon-4460	Aotus nancymaae	71.15	3e-14	71.6
LLPS-Sus-0385	Sus scrofa	71.15	5e-14	71.6
LLPS-Maf-1985	Macaca fascicularis	71.15	4e-14	71.2
LLPS-Chs-0409	Chlorocebus sabaeus	71.15	5e-14	71.6
LLPS-Ova-0876	Ovis aries	71.15	4e-14	71.2
LLPS-Ran-1498	Rattus norvegicus	71.15	5e-14	71.2
LLPS-Bot-1307	Bos taurus	71.15	5e-14	71.6
LLPS-Xim-0187	Xiphophorus maculatus	71.15	3e-14	71.2
LLPS-Tar-2658	Takifugu rubripes	71.15	4e-14	71.2
LLPS-Thc-0348	Theobroma cacao	70.9	2e-37	135
LLPS-Gas-1140	Galdieria sulphuraria	70.59	4e-11	62.0
LLPS-Drm-0795	Drosophila melanogaster	70.59	7e-13	67.4
LLPS-Gaga-0797	Gallus gallus	70.37	2e-14	72.4
LLPS-Asg-0227	Ashbya gossypii	70.0	4e-06	49.7
LLPS-Mae-1606	Manihot esculenta	69.57	3e-44	153
LLPS-Man-4225	Macaca nemestrina	69.23	5e-13	68.2
LLPS-Anp-1377	Anas platyrhynchos	69.23	4e-13	68.6
LLPS-Hos-0959	Homo sapiens	69.23	5e-13	68.6
LLPS-Fec-1261	Felis catus	69.23	1e-13	70.1
LLPS-Anc-2565	Anolis carolinensis	69.23	5e-13	68.6
LLPS-Mam-1030	Macaca mulatta	69.23	1e-13	70.1
LLPS-Cea-0150	Cercocebus atys	69.23	5e-13	68.2
LLPS-Cii-0744	Ciona intestinalis	69.23	1e-13	69.3
LLPS-Mal-0618	Mandrillus leucophaeus	69.23	5e-13	68.6
LLPS-Paa-1618	Papio anubis	69.23	5e-13	68.2
LLPS-Myl-1149	Myotis lucifugus	69.23	3e-13	68.9
LLPS-Mup-0135	Mustela putorius furo	69.23	3e-13	68.9
LLPS-Aim-0849	Ailuropoda melanoleuca	69.23	3e-13	68.9
LLPS-Tut-1666	Tursiops truncatus	69.23	4e-13	68.9
LLPS-Zyt-1097	Zymoseptoria tritici	67.65	1e-09	58.9
LLPS-Coc-0789	Corchorus capsularis	66.83	2e-44	153
LLPS-Phn-0722	Phaeosphaeria nodorum	65.71	7e-10	58.5
LLPS-Pytr-0808	Pyrenophora triticirepentis	65.71	7e-09	58.5
LLPS-Scc-0232	Schizosaccharomyces cryophilus	65.71	2e-08	55.8
LLPS-Lem-0654	Leptosphaeria maculans	65.71	3e-09	58.2
LLPS-Pyt-1414	Pyrenophora teres	65.71	1e-08	58.2
LLPS-Tru-0632	Triticum urartu	65.35	4e-19	85.9
LLPS-Chc-0836	Chondrus crispus	64.71	1e-08	55.5
LLPS-Gor-0108	Gossypium raimondii	64.25	2e-43	150
LLPS-Kop-0943	Komagataella pastoris	63.33	7e-06	47.4
LLPS-Prp-1410	Prunus persica	62.86	6e-39	139
LLPS-Asni-0184	Aspergillus niger	62.75	7e-07	51.6
LLPS-Viv-0342	Vitis vinifera	62.26	2e-45	156
LLPS-Pot-0952	Populus trichocarpa	61.95	2e-37	135
LLPS-Fus-0465	Fusarium solani	60.78	1e-09	59.3
LLPS-Cog-1367	Colletotrichum gloeosporioides	60.78	7e-10	59.7
LLPS-Trr-1173	Trichoderma reesei	60.78	1e-09	59.7
LLPS-Beb-0029	Beauveria bassiana	60.78	1e-09	58.9
LLPS-Cogr-0051	Colletotrichum graminicola	60.78	9e-10	59.3
LLPS-Trv-0934	Trichoderma virens	60.78	6e-10	59.7
LLPS-Fuo-0789	Fusarium oxysporum	60.78	8e-10	59.7
LLPS-Mao-0594	Magnaporthe oryzae	60.78	1e-09	59.3
LLPS-Coo-1211	Colletotrichum orbiculare	60.78	2e-09	59.3
LLPS-Scs-0159	Sclerotinia sclerotiorum	60.78	9e-07	50.8
LLPS-Fuv-0472	Fusarium verticillioides	60.78	9e-10	59.3
LLPS-Gag-0329	Gaeumannomyces graminis	60.78	9e-10	59.7
LLPS-Nec-0284	Neurospora crassa	60.78	1e-09	59.3
LLPS-Tum-0551	Tuber melanosporum	60.78	7e-10	60.1
LLPS-Blg-0339	Blumeria graminis	60.78	8e-07	51.2
LLPS-Crn-0623	Cryptococcus neoformans	59.65	1e-13	70.9
LLPS-Dos-0535	Dothistroma septosporum	58.82	2e-09	58.5
LLPS-Nia-0387	Nicotiana attenuata	54.74	2e-23	98.2
LLPS-Scp-1219	Schizosaccharomyces pombe	52.83	3e-09	57.8
LLPS-Spr-0727	Sporisorium reilianum	52.63	1e-08	56.6
LLPS-Usm-1200	Ustilago maydis	52.63	1e-08	56.6
LLPS-Mel-0935	Melampsora laricipopulina	51.92	4e-09	57.8
LLPS-Hea-0645	Helianthus annuus	50.92	2e-30	117
LLPS-Pug-1128	Puccinia graminis	50.91	3e-09	57.8
LLPS-Sol-0716	Solanum lycopersicum	50.0	1e-24	101
LLPS-Sot-0375	Solanum tuberosum	50.0	2e-24	100
LLPS-Dac-0747	Daucus carota	48.61	6e-28	110
LLPS-Abg-0494	Absidia glauca	45.31	3e-07	52.0

LLPS-Glm-0700100790892

Protein Sequence

Nucleotide Sequence

LLPS-Glm-0700
100790892