LLPS-Pot-0952
POPTR_003G058400
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | U1 small nuclear ribonucleoprotein C |
| Gene Name: | POPTR_003G058400 |
| Ensembl Gene: | POPTR_003G058400v3 |
| Ensembl Protein: | PNT43864 |
| Organism: | Populus trichocarpa |
| Taxa ID: | 3694 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Nucleolus, P-body | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | PNT43864 | PNT43864 |
| Ensembl | PNT43867 | PNT43867 |
| Ensembl | PNT43866 | PNT43866 |
| Ensembl | PNT43865 | PNT43865 |
| UniProt | B9GWP7, B9GWP7_POPTR | |
| GeneBank | CM009292 | PNT43864.1 |
| RefSeq | XM_002304134.2 | XP_002304170.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPRYYCDYCD TYLTHDSPSV RKQHNAGYKH KANVRIYYQQ FEEQQTQSII DQRIKEHLGQ 60 61 TAAFQQVGAA YNQHLMVQRP RLPVLPTPVM PIGGNNAPLF PGMRPPVLPR PMPGAPGYMN 120 121 PPMMPPMMAP PGAPSLPGQM NGIPRPPTMI AQPNVPGSTA APTPSGPPSM GPPVTYQANQ 180 181 AATTSGGFDS FNVNAAAPEA NH 202 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCCCGGT ATTACTGTGA TTATTGTGAC ACTTACTTGA CTCATGATTC TCCATCTGTT 60 61 AGAAAACAGC ACAATGCCGG TTATAAACAC AAGGCAAATG TGAGGATCTA TTATCAGCAG 120 121 TTTGAGGAGC AGCAAACCCA AAGTATAATT GATCAAAGAA TAAAGGAACA TCTTGGCCAA 180 181 ACTGCAGCTT TTCAACAGGT TGGTGCCGCA TACAATCAGC ATCTAATGGT CCAGAGACCC 240 241 CGGCTTCCTG TTCTTCCAAC TCCTGTGATG CCAATTGGAG GAAATAACGC CCCATTATTC 300 301 CCTGGGATGA GGCCTCCTGT TTTGCCTAGA CCAATGCCTG GTGCTCCAGG TTATATGAAC 360 361 CCTCCTATGA TGCCCCCAAT GATGGCACCC CCTGGTGCTC CTTCCTTACC TGGTCAAATG 420 421 AATGGCATTC CAAGGCCTCC TACAATGATT GCACAACCAA ATGTTCCTGG GAGTACTGCA 480 481 GCACCTACTC CTAGCGGTCC CCCGTCTATG GGTCCACCTG TTACTTACCA AGCAAATCAA 540 541 GCAGCAACAA CCAGTGGAGG CTTTGACAGC TTCAATGTGA ATGCCGCAGC CCCTGAAGCC 600 601 AATCATTAG 609 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Commitment complex | |
Cellular Component | U1 snRNP | |
Cellular Component | U2-type prespliceosome | |
Molecular Function | MRNA binding | |
Molecular Function | Pre-mRNA 5'-splice site binding | |
Molecular Function | U1 snRNA binding | |
Molecular Function | Zinc ion binding | |
Biological Process | MRNA 5'-splice site recognition | |
Biological Process | Spliceosomal snRNP assembly |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Amt-1071 | Amborella trichopoda | 85.06 | 2e-45 | 156 |
| LLPS-Chr-1297 | Chlamydomonas reinhardtii | 82.93 | 6e-17 | 80.5 |
| LLPS-Thc-0348 | Theobroma cacao | 82.89 | 5e-63 | 201 |
| LLPS-Lep-1288 | Leersia perrieri | 79.49 | 5e-58 | 189 |
| LLPS-Orp-0902 | Oryza punctata | 78.63 | 8e-57 | 185 |
| LLPS-Ors-1881 | Oryza sativa | 78.63 | 7e-57 | 186 |
| LLPS-Org-0717 | Oryza glaberrima | 78.63 | 7e-57 | 186 |
| LLPS-Orr-0987 | Oryza rufipogon | 78.63 | 5e-57 | 186 |
| LLPS-Orni-0671 | Oryza nivara | 78.63 | 7e-57 | 186 |
| LLPS-Ori-0787 | Oryza indica | 78.63 | 1e-56 | 185 |
| LLPS-Orb-0033 | Oryza barthii | 78.63 | 7e-57 | 186 |
| LLPS-Orgl-0942 | Oryza glumaepatula | 78.63 | 7e-57 | 186 |
| LLPS-Sei-1841 | Setaria italica | 77.59 | 7e-55 | 181 |
| LLPS-Brd-1941 | Brachypodium distachyon | 76.32 | 2e-53 | 176 |
| LLPS-Sob-0021 | Sorghum bicolor | 75.68 | 9e-46 | 159 |
| LLPS-Osl-0211 | Ostreococcus lucimarinus | 75.61 | 6e-17 | 76.6 |
| LLPS-Mae-1606 | Manihot esculenta | 75.6 | 2e-79 | 243 |
| LLPS-Viv-0342 | Vitis vinifera | 75.12 | 3e-64 | 204 |
| LLPS-Zem-1165 | Zea mays | 74.14 | 5e-47 | 162 |
| LLPS-Tra-2110 | Triticum aestivum | 74.14 | 8e-49 | 164 |
| LLPS-Coc-0789 | Corchorus capsularis | 73.91 | 4e-77 | 237 |
| LLPS-Art-2677 | Arabidopsis thaliana | 73.64 | 4e-48 | 162 |
| LLPS-Dac-0747 | Daucus carota | 72.81 | 3e-48 | 163 |
| LLPS-Bro-0756 | Brassica oleracea | 72.12 | 7e-44 | 151 |
| LLPS-Nia-0387 | Nicotiana attenuata | 72.07 | 3e-51 | 171 |
| LLPS-Brn-3340 | Brassica napus | 71.57 | 6e-42 | 146 |
| LLPS-Arl-0319 | Arabidopsis lyrata | 70.91 | 2e-45 | 155 |
| LLPS-Sot-0375 | Solanum tuberosum | 70.8 | 1e-40 | 143 |
| LLPS-Brr-1093 | Brassica rapa | 70.19 | 3e-43 | 149 |
| LLPS-Gor-2274 | Gossypium raimondii | 70.05 | 3e-68 | 214 |
| LLPS-Cae-0213 | Caenorhabditis elegans | 69.23 | 4e-21 | 90.5 |
| LLPS-Glm-0700 | Glycine max | 67.8 | 3e-55 | 181 |
| LLPS-Vir-0305 | Vigna radiata | 65.97 | 2e-42 | 149 |
| LLPS-Sem-1552 | Selaginella moellendorffii | 65.09 | 2e-33 | 130 |
| LLPS-Hov-0433 | Hordeum vulgare | 64.6 | 3e-37 | 135 |
| LLPS-Prp-1410 | Prunus persica | 64.56 | 2e-66 | 209 |
| LLPS-Otg-3029 | Otolemur garnettii | 64.52 | 5e-19 | 85.5 |
| LLPS-Nol-0102 | Nomascus leucogenys | 64.52 | 5e-19 | 85.5 |
| LLPS-Phv-1032 | Phaseolus vulgaris | 64.42 | 1e-52 | 174 |
| LLPS-Rhb-0610 | Rhinopithecus bieti | 64.06 | 3e-20 | 89.0 |
| LLPS-Pes-0245 | Pelodiscus sinensis | 64.06 | 2e-20 | 89.7 |
| LLPS-Man-4225 | Macaca nemestrina | 64.06 | 3e-20 | 89.0 |
| LLPS-Hos-0959 | Homo sapiens | 64.06 | 2e-20 | 89.0 |
| LLPS-Anc-2565 | Anolis carolinensis | 64.06 | 3e-20 | 89.0 |
| LLPS-Caj-0058 | Callithrix jacchus | 64.06 | 4e-20 | 88.6 |
| LLPS-Cea-0150 | Cercocebus atys | 64.06 | 3e-20 | 88.6 |
| LLPS-Sah-3884 | Sarcophilus harrisii | 64.06 | 3e-20 | 89.0 |
| LLPS-Aon-1684 | Aotus nancymaae | 64.06 | 4e-20 | 88.6 |
| LLPS-Paa-1618 | Papio anubis | 64.06 | 3e-20 | 88.6 |
| LLPS-Mal-0618 | Mandrillus leucophaeus | 64.06 | 2e-20 | 89.0 |
| LLPS-Scf-2731 | Scleropages formosus | 64.06 | 4e-20 | 89.0 |
| LLPS-Gaa-0599 | Gasterosteus aculeatus | 64.06 | 4e-20 | 87.8 |
| LLPS-Orn-0178 | Oreochromis niloticus | 63.64 | 3e-21 | 90.9 |
| LLPS-Fia-2645 | Ficedula albicollis | 63.64 | 2e-21 | 91.7 |
| LLPS-Orc-2670 | Oryctolagus cuniculus | 63.64 | 2e-21 | 91.7 |
| LLPS-Loa-0554 | Loxodonta africana | 63.64 | 2e-21 | 91.7 |
| LLPS-Lac-0427 | Latimeria chalumnae | 63.64 | 2e-21 | 92.0 |
| LLPS-Scm-2692 | Scophthalmus maximus | 63.64 | 2e-21 | 91.3 |
| LLPS-Mod-1345 | Monodelphis domestica | 63.64 | 2e-21 | 91.7 |
| LLPS-Urm-0872 | Ursus maritimus | 63.64 | 2e-21 | 92.0 |
| LLPS-Pap-1080 | Pan paniscus | 63.64 | 2e-21 | 91.7 |
| LLPS-Pat-0788 | Pan troglodytes | 63.64 | 2e-21 | 91.7 |
| LLPS-Pof-0303 | Poecilia formosa | 63.64 | 2e-21 | 91.3 |
| LLPS-Tag-2652 | Taeniopygia guttata | 63.64 | 5e-21 | 90.5 |
| LLPS-Ict-1398 | Ictidomys tridecemlineatus | 63.64 | 2e-21 | 91.7 |
| LLPS-Cas-1016 | Carlito syrichta | 63.64 | 2e-21 | 91.7 |
| LLPS-Gaga-0797 | Gallus gallus | 63.64 | 2e-21 | 92.0 |
| LLPS-Xet-0099 | Xenopus tropicalis | 63.64 | 2e-21 | 92.0 |
| LLPS-Eqc-2252 | Equus caballus | 63.64 | 3e-21 | 91.7 |
| LLPS-Cap-0529 | Cavia porcellus | 63.64 | 2e-21 | 91.7 |
| LLPS-Ten-0032 | Tetraodon nigroviridis | 63.64 | 9e-22 | 92.4 |
| LLPS-Caf-3721 | Canis familiaris | 63.64 | 3e-21 | 91.3 |
| LLPS-Poa-4533 | Pongo abelii | 63.64 | 3e-22 | 92.4 |
| LLPS-Icp-0909 | Ictalurus punctatus | 63.64 | 5e-22 | 93.2 |
| LLPS-Asm-1099 | Astyanax mexicanus | 63.64 | 2e-21 | 92.4 |
| LLPS-Fud-1400 | Fukomys damarensis | 63.64 | 2e-21 | 91.7 |
| LLPS-Gog-2228 | Gorilla gorilla | 63.64 | 2e-21 | 91.7 |
| LLPS-Sus-0385 | Sus scrofa | 63.64 | 3e-21 | 91.7 |
| LLPS-Chs-0409 | Chlorocebus sabaeus | 63.64 | 3e-21 | 91.7 |
| LLPS-Maf-1985 | Macaca fascicularis | 63.64 | 2e-21 | 91.7 |
| LLPS-Ova-0876 | Ovis aries | 63.64 | 2e-21 | 91.7 |
| LLPS-Ran-1498 | Rattus norvegicus | 63.64 | 3e-21 | 91.3 |
| LLPS-Bot-1307 | Bos taurus | 63.64 | 3e-21 | 91.7 |
| LLPS-Tar-2658 | Takifugu rubripes | 63.64 | 1e-21 | 91.7 |
| LLPS-Xim-0187 | Xiphophorus maculatus | 63.64 | 2e-21 | 91.3 |
| LLPS-Meg-0907 | Meleagris gallopavo | 63.49 | 1e-19 | 87.0 |
| LLPS-Orl-1191 | Oryzias latipes | 63.49 | 4e-20 | 89.4 |
| LLPS-Mum-0964 | Mus musculus | 63.49 | 1e-19 | 87.4 |
| LLPS-Php-2491 | Physcomitrella patens | 63.06 | 1e-25 | 104 |
| LLPS-Cus-0351 | Cucumis sativus | 62.56 | 9e-64 | 202 |
| LLPS-Sol-0716 | Solanum lycopersicum | 62.34 | 1e-40 | 143 |
| LLPS-Anp-1377 | Anas platyrhynchos | 62.12 | 3e-20 | 88.6 |
| LLPS-Fec-1261 | Felis catus | 62.12 | 4e-21 | 91.3 |
| LLPS-Mam-1603 | Macaca mulatta | 62.12 | 6e-20 | 87.8 |
| LLPS-Myl-1149 | Myotis lucifugus | 62.12 | 1e-20 | 89.4 |
| LLPS-Mup-0135 | Mustela putorius furo | 62.12 | 1e-20 | 89.4 |
| LLPS-Aim-0849 | Ailuropoda melanoleuca | 62.12 | 1e-20 | 89.7 |
| LLPS-Tut-1666 | Tursiops truncatus | 62.12 | 2e-20 | 89.4 |
| LLPS-Via-0252 | Vigna angularis | 61.54 | 2e-56 | 184 |
| LLPS-Met-0197 | Medicago truncatula | 61.46 | 5e-49 | 165 |
| LLPS-Tru-0632 | Triticum urartu | 61.27 | 9e-45 | 153 |
| LLPS-Fus-0465 | Fusarium solani | 60.78 | 1e-14 | 73.6 |
| LLPS-Trr-1173 | Trichoderma reesei | 60.78 | 1e-14 | 73.6 |
| LLPS-Beb-0029 | Beauveria bassiana | 60.78 | 1e-14 | 73.6 |
| LLPS-Fuo-0789 | Fusarium oxysporum | 60.78 | 6e-15 | 74.3 |
| LLPS-Trv-0934 | Trichoderma virens | 60.78 | 9e-15 | 73.6 |
| LLPS-Mao-0594 | Magnaporthe oryzae | 60.78 | 1e-14 | 73.6 |
| LLPS-Scs-0159 | Sclerotinia sclerotiorum | 60.78 | 2e-12 | 66.2 |
| LLPS-Fuv-0472 | Fusarium verticillioides | 60.78 | 6e-15 | 74.3 |
| LLPS-Gag-0329 | Gaeumannomyces graminis | 60.78 | 9e-15 | 73.9 |
| LLPS-Nec-0284 | Neurospora crassa | 60.78 | 7e-15 | 74.3 |
| LLPS-Dio-4359 | Dipodomys ordii | 60.61 | 9e-21 | 89.4 |
| LLPS-Drm-0795 | Drosophila melanogaster | 60.0 | 6e-20 | 87.4 |
| LLPS-Tum-0551 | Tuber melanosporum | 59.62 | 1e-15 | 76.3 |
| LLPS-Cii-0744 | Ciona intestinalis | 59.09 | 4e-20 | 87.4 |
| LLPS-Phn-0722 | Phaeosphaeria nodorum | 58.82 | 3e-15 | 73.6 |
| LLPS-Dos-0535 | Dothistroma septosporum | 58.82 | 9e-15 | 73.6 |
| LLPS-Pytr-0808 | Pyrenophora triticirepentis | 58.82 | 6e-14 | 73.2 |
| LLPS-Zyt-1097 | Zymoseptoria tritici | 58.82 | 6e-15 | 74.3 |
| LLPS-Lem-0654 | Leptosphaeria maculans | 58.82 | 2e-14 | 72.8 |
| LLPS-Pyt-1414 | Pyrenophora teres | 58.82 | 2e-13 | 72.8 |
| LLPS-Hea-0645 | Helianthus annuus | 57.99 | 3e-58 | 189 |
| LLPS-Crn-0623 | Cryptococcus neoformans | 57.89 | 1e-16 | 79.7 |
| LLPS-Ora-1923 | Ornithorhynchus anatinus | 57.14 | 2e-08 | 54.7 |
| LLPS-Chc-0836 | Chondrus crispus | 53.97 | 8e-13 | 67.0 |
| LLPS-Pug-1128 | Puccinia graminis | 53.85 | 7e-14 | 70.9 |
| LLPS-Blg-0339 | Blumeria graminis | 53.85 | 1e-12 | 67.4 |
| LLPS-Scp-1219 | Schizosaccharomyces pombe | 52.83 | 9e-13 | 67.8 |
| LLPS-Mua-1515 | Musa acuminata | 52.78 | 4e-54 | 178 |
| LLPS-Spr-0727 | Sporisorium reilianum | 52.63 | 3e-14 | 72.4 |
| LLPS-Usm-1200 | Ustilago maydis | 52.63 | 8e-14 | 71.2 |
| LLPS-Asni-0184 | Aspergillus niger | 51.56 | 1e-12 | 67.8 |
| LLPS-Dar-3281 | Danio rerio | 51.46 | 9e-22 | 92.4 |
| LLPS-Scc-0232 | Schizosaccharomyces cryophilus | 50.0 | 2e-11 | 63.9 |
| LLPS-Mel-0935 | Melampsora laricipopulina | 49.23 | 4e-14 | 72.0 |
| LLPS-Kop-0943 | Komagataella pastoris | 48.94 | 4e-07 | 50.8 |
| LLPS-Asc-1618 | Aspergillus clavatus | 48.33 | 4e-12 | 66.2 |
| LLPS-Cog-1367 | Colletotrichum gloeosporioides | 46.15 | 3e-15 | 75.1 |
| LLPS-Cogr-0051 | Colletotrichum graminicola | 46.15 | 9e-15 | 73.9 |
| LLPS-Coo-1211 | Colletotrichum orbiculare | 46.15 | 3e-15 | 75.5 |
| LLPS-Asg-0227 | Ashbya gossypii | 44.64 | 2e-07 | 53.5 |
| LLPS-Gas-1140 | Galdieria sulphuraria | 42.0 | 4e-15 | 73.2 |
| LLPS-Abg-0494 | Absidia glauca | 38.05 | 2e-13 | 69.7 |