• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Fud-0542
H920_13619

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: CTP synthase; UTP--ammonia ligase
Gene Name: H920_13619
Ensembl Gene: ENSFDAG00000016665.1
Ensembl Protein: ENSFDAP00000008273.1
Organism: Fukomys damarensis
Taxa ID: 885580
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-bodyPredicted from orthologs(View)

▼ FUNCTION

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKYILVTGGV  ISGIGKGIIA  SSIGTILKSC  GLRVTAIKID  PYINIDAGTF  SPYEHGEVFV  60
61    LNDGGEVDLD  LGNYERFLDI  NLYKDNNITT  GKIYHHVIKK  ERRGDYLGKT  VQVVPHITDA  120
121   IQEWVMNQSK  VPVDGNREEP  QICVIELGGT  IGDIEGMPFV  EAFRQFQFKA  KRENFYNIHV  180
181   SLVPQPSATG  EQKTKPTQNS  IRALRGLGLS  PDLIVCRSST  PIEMAVKEKI  SMFCHVKPEQ  240
241   VMCIHDVSST  YRVPVLLEQQ  GIVQHFKERL  DLPVGDSSSG  LLLRWGNMAD  RYEKLQKTCS  300
301   IALVGKYTKL  RDCYASVFKA  LEHSALAVNH  RLNLMYIDSI  DLEQDTKAQD  PVRFHEAWQK  360
361   LCTADGVLVP  GGFGLRGTLG  KMQAISWART  KKIPFLGVCL  GMQLAVIEFA  RNCLDMEDAN  420
421   STEFEPSTPV  PLVIDMPEHN  PGELGGTMRL  GLRRTVFKTQ  NSVLRKLYGD  VPFIEERHRH  480
481   RYEVNPSLIS  HFEQKDLAFV  GQDVDGNRME  IIELANHPYF  VGVQFHPEFS  SRPMKPSPPY  540
541   LGLLLAATGN  LRAYLQQMGP  PPP  563
Nucleotide CDS Sequence (FASTA)
1     ATGAAGTACA  TCCTGGTCAC  TGGTGGGGTC  ATCTCCGGCA  TTGGCAAAGG  GATCATCGCC  60
61    AGCAGCATCG  GGACCATCCT  CAAGTCCTGC  GGGCTCCGAG  TTACAGCCAT  CAAGATCGAC  120
121   CCCTATATTA  ACATTGATGC  GGGGACCTTC  TCACCCTACG  AGCACGGCGA  AGTGTTTGTC  180
181   TTAAATGATG  GTGGAGAAGT  TGATCTGGAT  CTTGGAAATT  ATGAGAGATT  CTTGGATATT  240
241   AATCTCTATA  AAGACAACAA  CATCACCACT  GGGAAGATCT  ATCACCACGT  GATCAAGAAG  300
301   GAGCGGCGCG  GAGACTACCT  GGGGAAGACA  GTACAAGTCG  TTCCCCACAT  CACCGACGCC  360
361   ATCCAAGAAT  GGGTCATGAA  TCAGTCCAAG  GTGCCAGTGG  ATGGGAACCG  GGAAGAGCCC  420
421   CAGATCTGCG  TCATAGAGCT  GGGAGGCACC  ATCGGGGACA  TCGAGGGCAT  GCCGTTTGTG  480
481   GAAGCCTTCA  GGCAGTTCCA  GTTCAAGGCG  AAGAGAGAGA  ATTTCTATAA  TATCCACGTC  540
541   AGCCTGGTCC  CTCAGCCCAG  TGCCACCGGG  GAACAGAAAA  CCAAGCCTAC  TCAGAACAGT  600
601   ATCCGGGCGC  TGAGAGGGCT  GGGCCTGTCT  CCGGATCTGA  TCGTCTGCCG  AAGCTCCACG  660
661   CCCATCGAGA  TGGCCGTGAA  GGAGAAGATC  TCCATGTTTT  GTCACGTGAA  ACCTGAACAG  720
721   GTCATGTGTA  TCCACGACGT  GTCTTCCACC  TACCGAGTGC  CTGTGCTCCT  GGAGCAGCAA  780
781   GGCATCGTGC  AGCACTTTAA  GGAGCGGCTG  GACCTGCCCG  TGGGCGACTC  CTCGAGCGGC  840
841   CTGCTGCTGC  GGTGGGGGAA  CATGGCCGAC  AGGTATGAAA  AGCTGCAGAA  GACCTGCTCC  900
901   ATAGCCCTGG  TCGGGAAGTA  CACCAAGCTC  CGGGACTGCT  ATGCATCTGT  GTTCAAGGCC  960
961   CTGGAGCACT  CGGCCCTGGC  TGTCAACCAC  AGGCTCAACC  TCATGTACAT  AGACTCCATC  1020
1021  GACCTGGAGC  AGGACACCAA  GGCCCAGGAC  CCCGTGAGGT  TCCACGAAGC  CTGGCAGAAG  1080
1081  CTGTGCACGG  CTGACGGTGT  TCTTGTGCCC  GGAGGCTTTG  GACTGAGAGG  AACGTTGGGG  1140
1141  AAAATGCAGG  CGATTTCTTG  GGCAAGGACA  AAGAAGATTC  CCTTTCTGGG  AGTCTGCCTC  1200
1201  GGGATGCAGC  TGGCTGTGAT  AGAGTTCGCG  CGAAATTGCC  TGGACATGGA  AGATGCTAAT  1260
1261  TCCACAGAGT  TTGAGCCCAG  CACCCCCGTC  CCTTTGGTGA  TCGATATGCC  AGAACACAAC  1320
1321  CCCGGGGAGC  TTGGCGGGAC  CATGAGGCTG  GGGCTAAGAA  GAACTGTCTT  CAAAACCCAG  1380
1381  AACTCAGTAC  TGAGGAAACT  GTACGGCGAT  GTCCCTTTCA  TTGAGGAGAG  ACACAGGCAT  1440
1441  CGGTACGAGG  TGAACCCTAG  CCTGATCAGC  CACTTTGAGC  AGAAAGATCT  GGCCTTTGTG  1500
1501  GGTCAGGATG  TTGACGGGAA  TCGGATGGAA  ATCATTGAAC  TGGCAAATCA  TCCCTATTTT  1560
1561  GTTGGTGTCC  AGTTCCACCC  TGAGTTTTCT  TCCAGGCCGA  TGAAGCCTTC  GCCTCCCTAC  1620
1621  TTGGGGCTCC  TGCTCGCAGC  CACAGGGAAC  TTGCGCGCCT  ACCTGCAGCA  GATGGGCCCG  1680
1681  CCACCCCCC  1689

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
Glutamine amidotransferase
Ligase
Nucleotide-binding
Pyrimidine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
ATP binding
Molecular Function
CTP synthase activity
Biological Process
'de novo' CTP biosynthetic process
Biological Process
Glutamine metabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ict-0345Ictidomys tridecemlineatus92.280.01048
LLPS-Cap-3294Cavia porcellus92.010.01040
LLPS-Dio-1866Dipodomys ordii90.860.01029
LLPS-Ova-2958Ovis aries90.840.01029
LLPS-Sus-2406Sus scrofa90.810.01026
LLPS-Bot-3347Bos taurus90.660.01028
LLPS-Urm-3721Ursus maritimus90.660.01026
LLPS-Fec-0686Felis catus90.660.01029
LLPS-Aim-1223Ailuropoda melanoleuca90.480.01025
LLPS-Mup-2896Mustela putorius furo90.480.01025
LLPS-Gog-2769Gorilla gorilla90.480.01026
LLPS-Poa-0321Pongo abelii90.480.01025
LLPS-Eqc-1695Equus caballus90.480.01025
LLPS-Nol-2757Nomascus leucogenys90.480.01025
LLPS-Myl-2765Myotis lucifugus90.310.01021
LLPS-Caf-0492Canis familiaris90.310.01022
LLPS-Hos-1508Homo sapiens90.310.01025
LLPS-Chs-3305Chlorocebus sabaeus90.130.01024
LLPS-Cea-0960Cercocebus atys90.130.01024
LLPS-Pat-2054Pan troglodytes90.130.01025
LLPS-Pap-4331Pan paniscus90.130.01025
LLPS-Orc-0591Oryctolagus cuniculus90.130.01023
LLPS-Cas-0454Carlito syrichta90.060.0 890
LLPS-Aon-1017Aotus nancymaae89.770.01006
LLPS-Caj-4381Callithrix jacchus89.590.01007
LLPS-Mal-0237Mandrillus leucophaeus89.530.0 939
LLPS-Maf-4017Macaca fascicularis89.220.0 955
LLPS-Ran-3287Rattus norvegicus88.350.01011
LLPS-Mum-4312Mus musculus88.260.01014
LLPS-Mam-1217Macaca mulatta88.190.0 815
LLPS-Loa-2141Loxodonta africana87.970.01006
LLPS-Ora-2544Ornithorhynchus anatinus86.360.0 971
LLPS-Sah-0315Sarcophilus harrisii86.360.0 975
LLPS-Mea-1468Mesocricetus auratus86.320.0 996
LLPS-Man-4240Macaca nemestrina85.380.0 947
LLPS-Pes-0339Pelodiscus sinensis84.20.0 953
LLPS-Mod-4387Monodelphis domestica84.150.0 959
LLPS-Gaga-3451Gallus gallus84.020.0 952
LLPS-Anp-1088Anas platyrhynchos84.020.0 951
LLPS-Fia-3673Ficedula albicollis84.020.0 947
LLPS-Anc-3047Anolis carolinensis83.660.0 943
LLPS-Tag-2415Taeniopygia guttata83.150.0 937
LLPS-Otg-0137Otolemur garnettii81.90.0 915
LLPS-Xet-1192Xenopus tropicalis80.760.0 924
LLPS-Meg-0164Meleagris gallopavo79.960.0 894
LLPS-Scf-0999Scleropages formosus76.480.0 865
LLPS-Leo-0675Lepisosteus oculatus76.480.0 871
LLPS-Asm-1171Astyanax mexicanus76.40.0 860
LLPS-Icp-0444Ictalurus punctatus76.220.0 852
LLPS-Dar-2974Danio rerio76.120.0 869
LLPS-Orl-1418Oryzias latipes75.680.0 858
LLPS-Xim-0625Xiphophorus maculatus75.580.0 863
LLPS-Paa-2541Papio anubis75.40.0 862
LLPS-Gaa-1522Gasterosteus aculeatus75.220.0 842
LLPS-Rhb-1359Rhinopithecus bieti75.220.0 859
LLPS-Pof-3154Poecilia formosa75.090.0 856
LLPS-Tut-2449Tursiops truncatus75.040.0 851
LLPS-Orn-0242Oreochromis niloticus75.040.0 825
LLPS-Scm-2293Scophthalmus maximus74.690.0 840
LLPS-Tar-0121Takifugu rubripes74.510.0 850
LLPS-Ten-2481Tetraodon nigroviridis73.390.0 834
LLPS-Lac-0326Latimeria chalumnae71.810.0 808
LLPS-Cii-1306Ciona intestinalis69.360.0 700
LLPS-Drm-2201Drosophila melanogaster65.050.0 729
LLPS-Cis-0032Ciona savignyi63.990.0 757
LLPS-Abg-0386Absidia glauca60.390.0 662
LLPS-Viv-1269Vitis vinifera59.430.0 639
LLPS-Sem-0584Selaginella moellendorffii59.270.0 627
LLPS-Sol-0641Solanum lycopersicum59.110.0 630
LLPS-Bro-1873Brassica oleracea59.030.0 630
LLPS-Prp-0783Prunus persica58.920.0 637
LLPS-Sob-0316Sorghum bicolor58.770.0 632
LLPS-Via-2368Vigna angularis58.760.0 633
LLPS-Brn-2300Brassica napus58.630.0 624
LLPS-Dac-1425Daucus carota58.530.0 635
LLPS-Mua-1749Musa acuminata58.450.0 636
LLPS-Phv-0477Phaseolus vulgaris58.390.0 627
LLPS-Nia-1784Nicotiana attenuata58.390.0 626
LLPS-Php-2049Physcomitrella patens58.350.0 651
LLPS-Brr-2316Brassica rapa58.320.0 623
LLPS-Mae-2133Manihot esculenta58.320.0 634
LLPS-Hea-0627Helianthus annuus57.990.0 639
LLPS-Gor-0674Gossypium raimondii57.990.0 624
LLPS-Coc-1341Corchorus capsularis57.910.0 629
LLPS-Arl-2001Arabidopsis lyrata57.820.0 636
LLPS-Glm-0420Glycine max57.810.0 622
LLPS-Tra-2871Triticum aestivum57.730.0 629
LLPS-Zem-1649Zea mays57.710.0 627
LLPS-Art-2157Arabidopsis thaliana57.60.0 618
LLPS-Pot-2410Populus trichocarpa57.450.0 622
LLPS-Cus-0365Cucumis sativus57.420.0 618
LLPS-Ori-1592Oryza indica57.420.0 629
LLPS-Org-2079Oryza glaberrima57.420.0 628
LLPS-Ors-1833Oryza sativa57.420.0 628
LLPS-Sot-1028Solanum tuberosum57.40.0 641
LLPS-Lep-1579Leersia perrieri57.370.0 629
LLPS-Thc-0464Theobroma cacao57.370.0 621
LLPS-Orr-0385Oryza rufipogon57.370.0 617
LLPS-Scp-1118Schizosaccharomyces pombe57.350.0 622
LLPS-Brd-0862Brachypodium distachyon57.220.0 627
LLPS-Orgl-1519Oryza glumaepatula57.190.0 627
LLPS-Orni-2224Oryza nivara57.190.0 627
LLPS-Orbr-0784Oryza brachyantha57.190.0 626
LLPS-Crn-1100Cryptococcus neoformans57.070.0 633
LLPS-Orm-0563Oryza meridionalis57.010.0 623
LLPS-Chr-0284Chlamydomonas reinhardtii56.990.0 637
LLPS-Sei-1109Setaria italica56.970.0 629
LLPS-Yal-1152Yarrowia lipolytica56.960.0 641
LLPS-Scc-1552Schizosaccharomyces cryophilus56.910.0 617
LLPS-Amt-2261Amborella trichopoda56.780.0 622
LLPS-Kop-0752Komagataella pastoris56.690.0 622
LLPS-Orp-0451Oryza punctata56.650.0 616
LLPS-Hov-0762Hordeum vulgare56.630.0 617
LLPS-Miv-0800Microbotryum violaceum56.350.0 631
LLPS-Met-1447Medicago truncatula56.270.0 624
LLPS-Ast-0178Aspergillus terreus56.230.0 596
LLPS-Mel-0255Melampsora laricipopulina56.080.0 602
LLPS-Tru-1996Triticum urartu55.910.0 619
LLPS-Orb-1003Oryza barthii55.830.0 617
LLPS-Asni-0665Aspergillus niger55.740.0 589
LLPS-Asg-0630Ashbya gossypii55.650.0 619
LLPS-Asc-0543Aspergillus clavatus55.540.0 600
LLPS-Blg-0572Blumeria graminis55.390.0 611
LLPS-Osl-0918Ostreococcus lucimarinus55.30.0 607
LLPS-Vir-0803Vigna radiata55.250.0 583
LLPS-Asfu-0662Aspergillus fumigatus55.180.0 590
LLPS-Nef-0712Neosartorya fischeri55.00.0 589
LLPS-Sac-0736Saccharomyces cerevisiae54.820.0 612
LLPS-Usm-0070Ustilago maydis54.090.0 628
LLPS-Scj-1061Schizosaccharomyces japonicus53.740.0 568
LLPS-Asn-0932Aspergillus nidulans53.570.0 582
LLPS-Nec-1361Neurospora crassa53.520.0 587
LLPS-Asf-0505Aspergillus flavus53.220.0 579
LLPS-Spr-0096Sporisorium reilianum52.90.0 617
LLPS-Dos-0000Dothistroma septosporum52.450.0 573
LLPS-Lem-0573Leptosphaeria maculans52.250.0 578
LLPS-Pyt-1259Pyrenophora teres52.160.0 575
LLPS-Gas-0463Galdieria sulphuraria51.540.0 575
LLPS-Cae-0055Caenorhabditis elegans50.490.0 577