• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Asc-0543
ACLA_006860

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: CTP synthase; UTP--ammonia ligase
Gene Name: ACLA_006860
Ensembl Gene: ACLA_006860
Ensembl Protein: EAW11928
Organism: Aspergillus clavatus
Taxa ID: 344612
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, OthersPredicted from orthologs(View)

▼ FUNCTION

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEAW11928EAW11928
UniProtA1CDK1, A1CDK1_ASPCL
GeneBankDS027051EAW11928.1
RefSeqXM_001273353.1XP_001273354.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKYVLVSGGV  ISGVGKGIIA  SSCGLLLKTA  GLAVSSIKID  PYLNPDAGLM  NPLEHGECFV  60
61    LDDGGEADLD  LGNYERYLGV  TLGRDNNITT  GKIYQHVIEK  ERRGDYLGKT  VQIVPHLTNE  120
121   IQNWVERVAR  VPVDESGREP  DVCIIELGGT  VGDIESAPFV  EAMSQLQRRA  GKNNFLEIHV  180
181   SYVPLIGSEQ  KTKPTQRAIS  DVRSAGLRPD  LIACRCETPL  EESTIQKIAN  ACQVERDQVV  240
241   GVHNVSTTYQ  VPILLEKQGF  LNTIKELLHI  DTVQKDPKLI  EHGKVIWQEW  HGLAMSQDRV  300
301   FETVSIALVG  KYTSLHDSYM  SVSKALEHSA  MHCKKKLDLI  WVESSHLEEE  HKDSNPSEYY  360
361   KAWHSVSTAD  GILVPGGFGE  RGTEGMIKSA  EWARTNNVPY  LGVCLGMQLA  VVEFARNVCG  420
421   MPNAGSAEFH  EHCEQPVIVY  MPEIDKTKMG  GTMRLGKRAT  IFQPGTEWSR  LRKLYGDKQE  480
481   VWERHRHRYE  VNPELVDQLE  QGGLTFVGKD  ESGKRMEIIE  LKDHKFFVGV  QFHPEYLSRV  540
541   LAPSKTFLGF  FAASAGCLDE  ITEVFKDPHD  LSHRELKVAV  Q  581

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
Glutamine amidotransferase
Ligase
Nucleotide-binding
Pyrimidine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
ATP binding
Molecular Function
CTP synthase activity
Biological Process
'de novo' CTP biosynthetic process
Biological Process
Glutamine metabolic process

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nef-0712Neosartorya fischeri93.560.01071
LLPS-Asfu-0662Aspergillus fumigatus93.560.01070
LLPS-Asn-0932Aspergillus nidulans83.150.0 971
LLPS-Asf-0505Aspergillus flavus80.250.0 952
LLPS-Aso-0523Aspergillus oryzae78.620.0 947
LLPS-Ast-0178Aspergillus terreus68.370.0 739
LLPS-Asni-0665Aspergillus niger67.890.0 743
LLPS-Blg-0572Blumeria graminis67.420.0 754
LLPS-Scc-1552Schizosaccharomyces cryophilus65.530.0 699
LLPS-Scp-1118Schizosaccharomyces pombe65.470.0 703
LLPS-Pyt-0548Pyrenophora teres64.270.0 741
LLPS-Pytr-1332Pyrenophora triticirepentis63.80.0 730
LLPS-Nec-1361Neurospora crassa63.740.0 712
LLPS-Lem-0573Leptosphaeria maculans63.350.0 724
LLPS-Gag-0056Gaeumannomyces graminis63.270.0 691
LLPS-Ved-1101Verticillium dahliae63.240.0 709
LLPS-Trr-0370Trichoderma reesei63.210.0 687
LLPS-Yal-1152Yarrowia lipolytica62.780.0 693
LLPS-Abg-0335Absidia glauca62.570.0 687
LLPS-Mao-0605Magnaporthe oryzae62.410.0 683
LLPS-Asg-0630Ashbya gossypii62.380.0 684
LLPS-Tum-1462Tuber melanosporum62.190.0 671
LLPS-Trv-1438Trichoderma virens62.080.0 690
LLPS-Sac-0023Saccharomyces cerevisiae61.990.0 685
LLPS-Miv-0800Microbotryum violaceum61.660.0 686
LLPS-Kop-0752Komagataella pastoris61.470.0 683
LLPS-Phn-0935Phaeosphaeria nodorum61.220.0 683
LLPS-Dos-0000Dothistroma septosporum60.890.0 657
LLPS-Cog-0803Colletotrichum gloeosporioides60.870.0 673
LLPS-Zyt-0045Zymoseptoria tritici60.690.0 647
LLPS-Coo-1272Colletotrichum orbiculare60.30.0 660
LLPS-Cogr-0804Colletotrichum graminicola60.040.0 662
LLPS-Crn-1100Cryptococcus neoformans59.930.0 673
LLPS-Fus-0855Fusarium solani59.190.0 684
LLPS-Put-0698Puccinia triticina58.650.0 552
LLPS-Fia-1264Ficedula albicollis57.730.0 600
LLPS-Ora-0483Ornithorhynchus anatinus57.540.0 592
LLPS-Mel-0255Melampsora laricipopulina57.410.0 616
LLPS-Gaga-1682Gallus gallus57.360.0 598
LLPS-Tag-0721Taeniopygia guttata57.360.0 598
LLPS-Spr-0096Sporisorium reilianum57.140.0 651
LLPS-Beb-0476Beauveria bassiana57.120.0 645
LLPS-Cap-0705Cavia porcellus56.980.0 588
LLPS-Orn-0242Oreochromis niloticus56.80.0 563
LLPS-Meg-2645Meleagris gallopavo56.80.0 551
LLPS-Usm-0070Ustilago maydis56.680.0 645
LLPS-Myl-2512Myotis lucifugus56.610.0 588
LLPS-Sem-1930Selaginella moellendorffii56.470.0 571
LLPS-Fud-1285Fukomys damarensis56.420.0 586
LLPS-Aon-1562Aotus nancymaae56.420.0 585
LLPS-Ran-0438Rattus norvegicus56.420.0 586
LLPS-Ova-1494Ovis aries56.420.0 585
LLPS-Dio-0414Dipodomys ordii56.420.0 584
LLPS-Otg-1431Otolemur garnettii56.420.0 587
LLPS-Anc-0420Anolis carolinensis56.420.0 595
LLPS-Gog-1305Gorilla gorilla56.240.0 581
LLPS-Maf-3671Macaca fascicularis56.240.0 580
LLPS-Mum-3315Mus musculus56.240.0 585
LLPS-Chs-1985Chlorocebus sabaeus56.240.0 580
LLPS-Sah-0315Sarcophilus harrisii56.240.0 587
LLPS-Cea-2239Cercocebus atys56.240.0 580
LLPS-Paa-2541Papio anubis56.240.0 581
LLPS-Mal-0567Mandrillus leucophaeus56.240.0 580
LLPS-Aim-1534Ailuropoda melanoleuca56.240.0 583
LLPS-Mup-0903Mustela putorius furo56.240.0 583
LLPS-Gaa-1522Gasterosteus aculeatus56.240.0 576
LLPS-Bot-1995Bos taurus56.240.0 585
LLPS-Hos-1793Homo sapiens56.240.0 581
LLPS-Mod-0481Monodelphis domestica56.240.0 582
LLPS-Man-1366Macaca nemestrina56.240.0 580
LLPS-Nol-1560Nomascus leucogenys56.240.0 580
LLPS-Caf-3004Canis familiaris56.240.0 583
LLPS-Mam-2769Macaca mulatta56.240.0 581
LLPS-Loa-0722Loxodonta africana56.220.0 580
LLPS-Icp-1961Ictalurus punctatus56.050.0 580
LLPS-Sus-1472Sus scrofa56.050.0 580
LLPS-Tut-2449Tursiops truncatus56.050.0 579
LLPS-Rhb-1359Rhinopithecus bieti56.050.0 578
LLPS-Dar-3272Danio rerio56.050.0 581
LLPS-Fec-0275Felis catus56.050.0 582
LLPS-Cas-0344Carlito syrichta56.050.0 583
LLPS-Poa-1287Pongo abelii56.050.0 580
LLPS-Eqc-2763Equus caballus56.050.0 581
LLPS-Php-2049Physcomitrella patens56.030.0 587
LLPS-Osl-0918Ostreococcus lucimarinus56.030.0 552
LLPS-Mea-2454Mesocricetus auratus55.870.0 580
LLPS-Pes-0339Pelodiscus sinensis55.870.0 577
LLPS-Anp-1088Anas platyrhynchos55.760.0 585
LLPS-Pat-0885Pan troglodytes55.740.0 568
LLPS-Pap-0100Pan paniscus55.740.0 568
LLPS-Caj-3404Callithrix jacchus55.680.0 570
LLPS-Orl-1418Oryzias latipes55.680.0 576
LLPS-Tar-1139Takifugu rubripes55.680.0 573
LLPS-Ten-2481Tetraodon nigroviridis55.640.0 572
LLPS-Xet-1707Xenopus tropicalis55.620.0 582
LLPS-Fuv-0729Fusarium verticillioides55.580.0 629
LLPS-Pof-3154Poecilia formosa55.580.0 579
LLPS-Xim-0625Xiphophorus maculatus55.490.0 577
LLPS-Scf-0999Scleropages formosus55.490.0 580
LLPS-Scm-2419Scophthalmus maximus55.490.0 572
LLPS-Asm-1171Astyanax mexicanus55.310.0 582
LLPS-Leo-0675Lepisosteus oculatus55.310.0 583
LLPS-Urm-3314Ursus maritimus55.310.0 570
LLPS-Dac-1425Daucus carota55.190.0 588
LLPS-Chr-0284Chlamydomonas reinhardtii55.170.0 561
LLPS-Lep-1873Leersia perrieri54.980.0 571
LLPS-Sob-0316Sorghum bicolor54.980.0 575
LLPS-Ori-1592Oryza indica54.80.0 573
LLPS-Ors-1833Oryza sativa54.80.0 573
LLPS-Org-2079Oryza glaberrima54.80.0 573
LLPS-Mua-1749Musa acuminata54.730.0 568
LLPS-Zem-1649Zea mays54.680.0 571
LLPS-Tra-2871Triticum aestivum54.430.0 579
LLPS-Orc-0591Oryctolagus cuniculus54.280.0 573
LLPS-Art-2216Arabidopsis thaliana54.260.0 575
LLPS-Orbr-1166Oryza brachyantha54.240.0 576
LLPS-Thc-0464Theobroma cacao54.130.0 568
LLPS-Nia-1784Nicotiana attenuata54.090.0 568
LLPS-Brn-3149Brassica napus54.070.0 574
LLPS-Brr-0617Brassica rapa54.070.0 574
LLPS-Pot-0587Populus trichocarpa53.90.0 576
LLPS-Hea-0627Helianthus annuus53.890.0 587
LLPS-Cus-0365Cucumis sativus53.890.0 573
LLPS-Fuo-1311Fusarium oxysporum53.860.0 576
LLPS-Orp-0495Oryza punctata53.820.0 555
LLPS-Hov-0762Hordeum vulgare53.760.0 567
LLPS-Sol-0383Solanum lycopersicum53.720.0 561
LLPS-Prp-0783Prunus persica53.720.0 573
LLPS-Arl-1597Arabidopsis lyrata53.70.0 568
LLPS-Glm-0420Glycine max53.690.0 578
LLPS-Met-2082Medicago truncatula53.690.0 580
LLPS-Phv-1639Phaseolus vulgaris53.690.0 577
LLPS-Bro-0251Brassica oleracea53.520.0 571
LLPS-Brd-0862Brachypodium distachyon53.480.0 557
LLPS-Viv-1736Vitis vinifera53.470.0 550
LLPS-Via-2368Vigna angularis53.370.0 560
LLPS-Orni-2224Oryza nivara53.350.0 580
LLPS-Orgl-1519Oryza glumaepatula53.350.0 580
LLPS-Coc-1432Corchorus capsularis53.330.0 569
LLPS-Amt-0022Amborella trichopoda53.250.0 563
LLPS-Orb-1003Oryza barthii53.230.0 561
LLPS-Orm-1833Oryza meridionalis53.220.0 553
LLPS-Tru-1840Triticum urartu53.140.0 554
LLPS-Orr-2111Oryza rufipogon53.040.0 550
LLPS-Sot-1028Solanum tuberosum52.980.0 583
LLPS-Gor-2196Gossypium raimondii52.970.0 565
LLPS-Mae-0009Manihot esculenta52.910.0 567
LLPS-Ict-0345Ictidomys tridecemlineatus52.560.0 575
LLPS-Drm-2201Drosophila melanogaster52.420.0 549
LLPS-Sei-0135Setaria italica51.990.0 560
LLPS-Vir-0559Vigna radiata50.350.0 542