• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-1141
PDCD4

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Programmed cell death 4
Gene Name: PDCD4
Ensembl Gene: ENSECAG00000020935.2
Ensembl Protein: ENSECAP00000035281.1
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MWEWSAIILV  MLARARSWKD  LKLQDPDNLS  DSLFSGDEEN  TGTEEIKNEI  NGNWISASSI  60
61    NEARINAKAK  RRLRKNSSRD  SGRGDSVSDN  GSEALRSGVT  VPTSPKGRLL  DRRSRSGKGR  120
121   GLPKKGGAGG  KGVWGTPGQV  YDVEEVDVKD  PNYDDDQENC  VYETVVLPLD  ETAFEKTLTP  180
181   IIQEYFEHGD  TNEVAEMLRD  LNLGEMKSGV  PVLAVSLALE  GKASHREMTS  KLLSDLCGTV  240
241   MSTNDVEKSF  DKLLKDLPEL  ALDTPRAPQL  VGQFIARAVG  DGILCNTYID  SYKGTVDCVQ  300
301   ARAALDKATV  LLSMSKGGKR  KDSVWGSGGG  QQSVNHLVKE  IDMLLKEYLL  SGDISEAEHC  360
361   LKELEVPHFH  HELVYEAIVM  VLESTGESTF  KMILDLLKSL  WKSSTITLDQ  MKRGYERIYN  420
421   EIPDINLDVP  HSYSVLERFV  EECFQAGIIS  KQLRDLCPSR  GRKRFVSEGD  GGRLKPESY  479
Nucleotide CDS Sequence (FASTA)
1     ATGTGGGAGT  GGTCAGCAAT  CATTCTGGTG  ATGTTAGCAA  GGGCAAGATC  ATGGAAGGAC  60
61    CTTAAGTTAC  AAGATCCTGA  TAATTTAAGT  GACTCTCTCT  TTTCTGGCGA  TGAAGAAAAT  120
121   ACTGGGACTG  AGGAAATAAA  GAATGAGATA  AATGGAAATT  GGATTTCGGC  ATCCTCCATT  180
181   AATGAAGCTA  GAATTAATGC  CAAGGCTAAA  AGACGACTAC  GGAAAAACTC  ATCCCGGGAC  240
241   TCTGGCAGAG  GCGATTCGGT  CAGTGATAAC  GGAAGTGAAG  CCCTTAGAAG  TGGAGTAACT  300
301   GTACCAACCA  GTCCAAAGGG  AAGGTTGCTA  GACAGGCGAT  CCAGATCTGG  GAAAGGAAGG  360
361   GGACTACCAA  AGAAAGGTGG  TGCAGGAGGC  AAAGGTGTCT  GGGGTACACC  TGGACAGGTA  420
421   TATGATGTGG  AGGAAGTAGA  TGTGAAGGAT  CCTAACTATG  ATGATGACCA  GGAGAACTGT  480
481   GTTTATGAAA  CTGTGGTTTT  GCCTTTGGAT  GAAACGGCAT  TTGAGAAAAC  TTTAACACCA  540
541   ATCATACAGG  AATATTTTGA  GCATGGAGAT  ACTAATGAAG  TTGCGGAAAT  GCTAAGAGAT  600
601   TTAAATCTTG  GTGAAATGAA  AAGTGGAGTA  CCAGTGTTGG  CAGTGTCCTT  GGCATTGGAG  660
661   GGAAAGGCTA  GTCACAGAGA  AATGACATCT  AAGCTCCTTT  CTGACCTTTG  TGGGACGGTA  720
721   ATGAGCACAA  ACGATGTAGA  AAAGTCATTT  GATAAATTGT  TGAAAGATCT  ACCTGAATTA  780
781   GCACTGGATA  CTCCTAGAGC  ACCACAGTTG  GTGGGCCAGT  TTATTGCTAG  AGCTGTTGGA  840
841   GATGGAATTT  TATGTAATAC  CTATATTGAT  AGTTACAAAG  GAACTGTAGA  TTGTGTACAG  900
901   GCTAGAGCTG  CCCTGGATAA  GGCTACTGTG  CTCCTGAGTA  TGTCTAAAGG  TGGAAAGCGC  960
961   AAAGACAGCG  TGTGGGGCTC  TGGAGGTGGG  CAGCAGTCTG  TTAACCACCT  TGTTAAAGAG  1020
1021  ATTGATATGC  TGCTGAAAGA  ATATTTACTC  TCTGGAGACA  TATCTGAGGC  TGAACATTGC  1080
1081  CTTAAGGAAC  TGGAAGTACC  TCATTTTCAC  CATGAGCTTG  TATATGAAGC  CATTGTAATG  1140
1141  GTTTTAGAGT  CAACTGGAGA  AAGTACATTT  AAGATGATTT  TGGATTTATT  AAAATCCCTT  1200
1201  TGGAAATCTT  CTACCATTAC  TCTAGACCAA  ATGAAAAGAG  GTTATGAGAG  AATTTACAAT  1260
1261  GAAATTCCGG  ATATTAATCT  GGATGTCCCA  CATTCATACT  CTGTGCTTGA  ACGATTTGTA  1320
1321  GAAGAATGTT  TTCAGGCTGG  AATAATTTCC  AAACAACTCA  GAGATCTTTG  TCCTTCAAGG  1380
1381  GGCAGAAAAC  GTTTTGGAGC  ATACTGA  1407

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mup-0498Mustela putorius furo99.780.0 802
LLPS-Caf-4530Canis familiaris99.340.0 797
LLPS-Cas-3717Carlito syrichta99.340.0 798
LLPS-Mea-2992Mesocricetus auratus99.120.0 799
LLPS-Fec-4783Felis catus99.120.0 797
LLPS-Dio-1628Dipodomys ordii98.90.0 796
LLPS-Gog-0930Gorilla gorilla98.680.0 792
LLPS-Pat-1489Pan troglodytes98.680.0 793
LLPS-Pap-3879Pan paniscus98.680.0 793
LLPS-Otg-2442Otolemur garnettii98.680.0 792
LLPS-Urm-3282Ursus maritimus98.480.0 800
LLPS-Sus-4211Sus scrofa98.460.0 793
LLPS-Mum-0801Mus musculus98.460.0 794
LLPS-Orc-2343Oryctolagus cuniculus98.460.0 793
LLPS-Ova-3538Ovis aries98.240.0 790
LLPS-Mal-3962Mandrillus leucophaeus98.240.0 790
LLPS-Paa-3955Papio anubis98.240.0 790
LLPS-Aon-3993Aotus nancymaae98.240.0 791
LLPS-Ict-3685Ictidomys tridecemlineatus98.240.0 791
LLPS-Hos-3828Homo sapiens98.240.0 792
LLPS-Myl-2602Myotis lucifugus98.020.0 792
LLPS-Ran-4353Rattus norvegicus98.020.0 792
LLPS-Cea-2234Cercocebus atys98.020.0 790
LLPS-Caj-3019Callithrix jacchus98.020.0 788
LLPS-Mam-3528Macaca mulatta98.020.0 787
LLPS-Nol-4455Nomascus leucogenys98.020.0 782
LLPS-Aim-2080Ailuropoda melanoleuca97.830.0 795
LLPS-Bot-3671Bos taurus97.80.0 787
LLPS-Chs-2063Chlorocebus sabaeus97.80.0 788
LLPS-Fud-0288Fukomys damarensis97.80.0 788
LLPS-Poa-3723Pongo abelii97.580.0 780
LLPS-Cap-1711Cavia porcellus97.140.0 781
LLPS-Sah-1964Sarcophilus harrisii96.910.0 777
LLPS-Mod-3659Monodelphis domestica96.910.0 777
LLPS-Maf-0837Macaca fascicularis96.750.0 788
LLPS-Man-2265Macaca nemestrina96.750.0 788
LLPS-Rhb-4554Rhinopithecus bieti95.80.0 756
LLPS-Ora-0937Ornithorhynchus anatinus94.960.0 769
LLPS-Loa-2885Loxodonta africana90.370.0 719
LLPS-Fia-1126Ficedula albicollis88.080.0 693
LLPS-Tag-1332Taeniopygia guttata87.860.0 691
LLPS-Gaga-3889Gallus gallus87.640.0 698
LLPS-Anp-2784Anas platyrhynchos87.640.0 696
LLPS-Pes-0037Pelodiscus sinensis87.640.0 682
LLPS-Meg-3038Meleagris gallopavo86.750.0 689
LLPS-Anc-0272Anolis carolinensis85.930.0 689
LLPS-Xet-1249Xenopus tropicalis76.80.0 593
LLPS-Leo-0275Lepisosteus oculatus71.910.0 580
LLPS-Lac-2491Latimeria chalumnae71.640.0 580
LLPS-Asm-3156Astyanax mexicanus71.370.0 537
LLPS-Scf-3007Scleropages formosus70.950.0 555
LLPS-Dar-4184Danio rerio69.070.0 549
LLPS-Icp-3080Ictalurus punctatus68.220.0 531
LLPS-Orn-2565Oreochromis niloticus67.860.0 534
LLPS-Orl-3849Oryzias latipes67.846e-160 468
LLPS-Pof-2161Poecilia formosa67.159e-174 504
LLPS-Gaa-0971Gasterosteus aculeatus66.452e-172 501
LLPS-Scm-3401Scophthalmus maximus66.114e-178 515
LLPS-Tar-2980Takifugu rubripes64.696e-173 502
LLPS-Ten-3386Tetraodon nigroviridis63.927e-165 481
LLPS-Xim-0897Xiphophorus maculatus63.112e-159 468
LLPS-Cii-2199Ciona intestinalis43.814e-77 255
LLPS-Drm-2019Drosophila melanogaster42.181e-77 258
LLPS-Cis-2071Ciona savignyi41.191e-75 251
LLPS-Via-1892Vigna angularis33.737e-35 142
LLPS-Vir-1876Vigna radiata33.738e-35 142
LLPS-Sei-1444Setaria italica33.75e-30 128
LLPS-Viv-0163Vitis vinifera33.642e-34 141
LLPS-Phv-1438Phaseolus vulgaris33.439e-35 142
LLPS-Orbr-0163Oryza brachyantha33.338e-30 127
LLPS-Sob-1741Sorghum bicolor33.337e-30 127
LLPS-Nia-2624Nicotiana attenuata33.138e-35 142
LLPS-Cus-0623Cucumis sativus33.032e-32 135
LLPS-Org-1896Oryza glaberrima33.026e-36 145
LLPS-Pot-2231Populus trichocarpa33.023e-33 137
LLPS-Coc-1389Corchorus capsularis33.011e-31 132
LLPS-Hea-0247Helianthus annuus33.09e-34 138
LLPS-Lep-0563Leersia perrieri32.975e-29 124
LLPS-Php-1996Physcomitrella patens32.93e-35 143
LLPS-Orgl-1079Oryza glumaepatula32.821e-35 144
LLPS-Ori-1400Oryza indica32.821e-35 144
LLPS-Orb-1723Oryza barthii32.821e-35 144
LLPS-Orr-1241Oryza rufipogon32.821e-35 144
LLPS-Orm-1009Oryza meridionalis32.828e-36 145
LLPS-Orp-2404Oryza punctata32.821e-34 142
LLPS-Ors-1969Oryza sativa32.821e-35 144
LLPS-Sol-1136Solanum lycopersicum32.84e-33 137
LLPS-Thc-2180Theobroma cacao32.681e-31 133
LLPS-Brd-0810Brachypodium distachyon32.612e-36 147
LLPS-Met-2157Medicago truncatula32.523e-30 128
LLPS-Orni-1797Oryza nivara32.513e-35 143
LLPS-Hov-2030Hordeum vulgare32.52e-37 150
LLPS-Gor-2627Gossypium raimondii32.54e-33 137
LLPS-Glm-0865Glycine max32.322e-32 135
LLPS-Mae-2080Manihot esculenta32.328e-28 121
LLPS-Tra-0747Triticum aestivum32.34e-38 151
LLPS-Tru-1224Triticum urartu32.34e-38 150
LLPS-Zem-1181Zea mays32.257e-29 124
LLPS-Mua-1772Musa acuminata32.192e-34 139
LLPS-Prp-0133Prunus persica32.047e-32 133
LLPS-Bro-2874Brassica oleracea32.044e-26 116
LLPS-Brn-2563Brassica napus31.692e-25 114
LLPS-Brr-0026Brassica rapa31.692e-25 114
LLPS-Sem-1095Selaginella moellendorffii31.613e-36 145
LLPS-Amt-0164Amborella trichopoda31.567e-28 121
LLPS-Chr-1522Chlamydomonas reinhardtii31.533e-32 135
LLPS-Dac-2381Daucus carota31.521e-26 117
LLPS-Art-2867Arabidopsis thaliana31.346e-25 112
LLPS-Arl-1294Arabidopsis lyrata31.055e-25 112
LLPS-Sot-1122Solanum tuberosum29.61e-22 105
LLPS-Osl-1203Ostreococcus lucimarinus27.485e-28 118