• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cogr-1582
GLRG_18005

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cytochrome c oxidase subunit 1
Gene Name: GLRG_18005
Ensembl Gene: GLRG_18005
Ensembl Protein: EFQ24846
Organism: Colletotrichum graminicola
Taxa ID: 645133
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
OthersPredicted from orthologs(View)

▼ FUNCTION

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEFQ24846EFQ24846
UniProtE3CUA0, E3CUA0_COLGM
GeneBankCM001021EFQ24846.1
RefSeqNW_007361658.1XP_008100886.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNAERWFLST  NAKDIGTLYL  IFALFSGLLG  TAFSVLIRLE  LSGPGVQYIS  DNQLYNSIIT  60
61    AHAILMIFFM  VMPALIGGFG  NFLMPLMVGG  PDMAFPRLNN  ISFWLLPPSL  ILLVFSACIE  120
121   GGVGTGWTLY  PPLSGLQSHS  GPSVDLAIFA  LHLSGVSSLL  GAVNFITTVV  NMRTPGIKLH  180
181   KLALFGWAVV  ITAVLLLLSL  PVLAGGITMV  LTDRNFNTSF  FETAGGGDPI  LYQHLFWFFG  240
241   HPEVYILIIP  GFGIISTTIS  ASSNKSIFGY  IGMVYAMMSI  GILGFIVWSH  HMYTVGLDVD  300
301   TRAYFTAATL  IIAVPTGIKI  FSWLATSYGG  SIKLTPSMLF  ALGFVFMFTI  GGLSGVVLAN  360
361   ASLDIAFHDT  YYVVAHFHYV  LSMGAVFAMF  SGWYYWIPKI  LGLNYNIVLA  KIQFWVLFIG  420
421   VNLTFFPQHF  LGLQGMPRRI  SDYPDAFAGW  NLISSFGSII  SVVAAWLFLY  IVYKQLVEGK  480
481   VASRNPWSSV  QYYTDTLQAL  LNRSYPSLEW  ALSSPPKPHA  FVSLPLQSRF  CFRFL  535
Nucleotide CDS Sequence (FASTA)
1     ATGAATGCCG  AAAGATGATT  TTTATCTACA  AACGCTAAAG  ATATTGGGAC  TTTATATTTA  60
61    ATTTTTGCTT  TATTTTCAGG  ATTATTAGGT  ACAGCTTTCT  CTGTATTAAT  AAGATTAGAG  120
121   TTAAGTGGAC  CAGGAGTTCA  ATATATTTCA  GATAACCAAT  TATATAATAG  TATAATTACA  180
181   GCTCATGCTA  TTCTTATGAT  ATTCTTTATG  GTTATGCCAG  CCTTAATTGG  AGGTTTTGGT  240
241   AACTTCTTAA  TGCCTTTAAT  GGTAGGTGGA  CCGGATATGG  CCTTTCCAAG  ATTAAATAAC  300
301   ATAAGTTTTT  GACTATTACC  ACCTAGTTTA  ATACTATTAG  TATTCTCTGC  ATGTATAGAA  360
361   GGTGGAGTTG  GAACAGGGTG  AACATTATAT  CCTCCTTTAT  CAGGATTACA  AAGTCATAGT  420
421   GGTCCTAGTG  TAGATTTAGC  TATATTTGCT  TTACATTTAT  CAGGGGTAAG  TAGTTTATTA  480
481   GGTGCCGTTA  ATTTTATTAC  TACTGTAGTA  AATATGAGAA  CACCAGGTAT  AAAATTACAT  540
541   AAATTAGCTT  TATTCGGATG  AGCTGTTGTT  ATAACAGCAG  TCTTATTATT  ATTATCTTTA  600
601   CCTGTGTTAG  CTGGGGGTAT  TACAATGGTA  TTAACAGATA  GAAACTTTAA  TACATCATTC  660
661   TTTGAAACAG  CCGGTGGAGG  TGATCCTATA  TTATATCAAC  ATCTTTTCTG  ATTCTTCGGT  720
721   CACCCAGAGG  TTTATATATT  AATTATACCT  GGTTTTGGTA  TAATAAGTAC  AACTATTTCT  780
781   GCTAGCTCTA  ATAAAAGTAT  TTTTGGATAT  ATAGGAATGG  TTTATGCTAT  GATGTCTATT  840
841   GGTATATTAG  GATTCATAGT  TTGATCTCAT  CATATGTATA  CAGTAGGTTT  AGACGTTGAT  900
901   ACTAGAGCGT  ACTTTACAGC  TGCTACATTA  ATTATTGCAG  TTCCTACTGG  AATTAAAATA  960
961   TTCTCATGAT  TAGCTACATC  CTACGGAGGA  TCTATAAAAT  TAACTCCTTC  TATGTTATTT  1020
1021  GCATTAGGAT  TTGTATTTAT  GTTTACAATA  GGAGGATTAA  GTGGGGTTGT  TTTAGCAAAT  1080
1081  GCTTCACTTG  ATATTGCATT  CCACGATACT  TACTACGTTG  TAGCTCATTT  CCACTATGTT  1140
1141  TTAAGTATGG  GTGCAGTTTT  TGCCATGTTT  AGTGGTTGAT  ATTACTGAAT  ACCTAAAATA  1200
1201  TTAGGTTTAA  ACTATAATAT  CGTATTAGCC  AAAATACAAT  TCTGAGTTTT  ATTTATAGGG  1260
1261  GTTAATTTAA  CATTCTTCCC  ACAACATTTC  TTAGGATTAC  AAGGTATGCC  TAGACGTATT  1320
1321  AGCGATTACC  CTGACGCTTT  TGCAGGATGA  AATTTAATTA  GTAGTTTTGG  ATCTATTATA  1380
1381  AGCGTAGTAG  CTGCATGATT  ATTCTTATAC  ATAGTATACA  AACAATTAGT  TGAAGGTAAA  1440
1441  GTTGCCAGCA  GAAATCCATG  ATCTTCTGTA  CAATATTACA  CTGATACTTT  ACAAGCTCTT  1500
1501  TTAAATAGAA  GTTATCCTAG  CTTAGAATGA  GCATTAAGTA  GCCCTCCTAA  ACCTCATGCT  1560
1561  TTTGTAAGTT  TACCTTTACA  AAGTCGGTTT  TGTTTTCGTT  TTCTCTAA  1608

▼ KEYWORD

ID
Family
Complete proteome
Copper
Electron transport
Heme
Iron
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Oxidoreductase
Reference proteome
Respiratory chain
Transmembrane
Transmembrane helix
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of membrane
Cellular Component
Mitochondrial inner membrane
Cellular Component
Respiratory chain complex IV
Molecular Function
Cytochrome-c oxidase activity
Molecular Function
Heme binding
Molecular Function
Metal ion binding
Biological Process
Aerobic respiration
Biological Process
Oxidative phosphorylation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Chc-1042Chondrus crispus96.778e-1162.8
LLPS-Nec-1255Neurospora crassa91.60.0 922
LLPS-Amt-1584Amborella trichopoda84.854e-1168.2
LLPS-Phn-0837Phaeosphaeria nodorum83.430.0 835
LLPS-Spr-1352Sporisorium reilianum73.190.0 728
LLPS-Sot-1594Solanum tuberosum72.732e-131 392
LLPS-Met-2377Medicago truncatula70.971e-38 142
LLPS-Glm-3014Glycine max70.373e-31 120
LLPS-Sob-1598Sorghum bicolor70.151e-1372.0
LLPS-Viv-2067Vitis vinifera68.991e-43 159
LLPS-Ori-1667Oryza indica68.740.0 547
LLPS-Tru-1823Triticum urartu68.280.0 656
LLPS-Orbr-0672Oryza brachyantha68.01e-24 102
LLPS-Art-3043Arabidopsis thaliana67.930.0 666
LLPS-Org-1946Oryza glaberrima67.930.0 665
LLPS-Zem-1415Zea mays67.930.0 664
LLPS-Sei-0631Setaria italica67.930.0 665
LLPS-Hov-0247Hordeum vulgare67.740.0 664
LLPS-Tra-2041Triticum aestivum67.550.0 663
LLPS-Lem-1154Leptosphaeria maculans66.675e-33 128
LLPS-Nia-2569Nicotiana attenuata66.60.0 609
LLPS-Gor-0296Gossypium raimondii65.840.0 635
LLPS-Cym-0896Cyanidioschyzon merolae65.770.0 682
LLPS-Sac-1005Saccharomyces cerevisiae65.230.0 687
LLPS-Dac-0545Daucus carota65.20.0 589
LLPS-Dar-3194Danio rerio64.370.0 618
LLPS-Hea-2110Helianthus annuus64.330.0 618
LLPS-Sol-1807Solanum lycopersicum64.330.0 530
LLPS-Tar-2687Takifugu rubripes63.980.0 613
LLPS-Orl-3238Oryzias latipes63.60.0 610
LLPS-Mod-2996Monodelphis domestica63.410.0 615
LLPS-Sah-3878Sarcophilus harrisii63.410.0 618
LLPS-Drm-1685Drosophila melanogaster63.260.0 618
LLPS-Scf-2556Scleropages formosus63.220.0 610
LLPS-Tag-2443Taeniopygia guttata63.20.0 614
LLPS-Ten-2621Tetraodon nigroviridis63.130.0 598
LLPS-Sus-3456Sus scrofa63.030.0 615
LLPS-Eqc-3649Equus caballus63.010.0 613
LLPS-Ova-2685Ovis aries63.010.0 612
LLPS-Gaa-1100Gasterosteus aculeatus62.930.0 610
LLPS-Icp-3033Ictalurus punctatus62.840.0 607
LLPS-Xim-3760Xiphophorus maculatus62.840.0 608
LLPS-Fia-2249Ficedula albicollis62.810.0 612
LLPS-Loa-1514Loxodonta africana62.640.0 618
LLPS-Ict-1728Ictidomys tridecemlineatus62.640.0 613
LLPS-Ora-3285Ornithorhynchus anatinus62.640.0 610
LLPS-Ran-0050Rattus norvegicus62.640.0 613
LLPS-Anc-2465Anolis carolinensis62.620.0 599
LLPS-Orc-0500Oryctolagus cuniculus62.450.0 612
LLPS-Leo-1781Lepisosteus oculatus62.450.0 606
LLPS-Mum-3502Mus musculus62.450.0 612
LLPS-Meg-2700Meleagris gallopavo62.430.0 604
LLPS-Gaga-1222Gallus gallus62.430.0 597
LLPS-Cap-1641Cavia porcellus62.430.0 609
LLPS-Fud-1329Fukomys damarensis62.430.0 612
LLPS-Asg-0401Ashbya gossypii62.310.0 674
LLPS-Rhb-1454Rhinopithecus bieti62.260.0 626
LLPS-Fec-0793Felis catus62.260.0 613
LLPS-Mea-1548Mesocricetus auratus62.260.0 610
LLPS-Coc-2320Corchorus capsularis62.240.0 583
LLPS-Pot-2137Populus trichocarpa62.165e-0650.4
LLPS-Cas-2465Carlito syrichta62.070.0 608
LLPS-Tut-1906Tursiops truncatus62.070.0 624
LLPS-Caf-3987Canis familiaris62.040.0 612
LLPS-Bro-1562Brassica oleracea62.032e-49 171
LLPS-Hos-3951Homo sapiens61.880.0 600
LLPS-Pap-3613Pan paniscus61.880.0 602
LLPS-Xet-0613Xenopus tropicalis61.880.0 605
LLPS-Pat-2350Pan troglodytes61.690.0 601
LLPS-Chs-3275Chlorocebus sabaeus61.690.0 620
LLPS-Ere-0617Erinaceus europaeus61.690.0 629
LLPS-Aim-2252Ailuropoda melanoleuca61.660.0 610
LLPS-Urm-2682Ursus maritimus61.490.0 612
LLPS-Poa-2054Pongo abelii61.490.0 601
LLPS-Gog-4345Gorilla gorilla61.490.0 603
LLPS-Maf-0678Macaca fascicularis61.490.0 624
LLPS-Mal-3599Mandrillus leucophaeus61.460.0 623
LLPS-Lac-4021Latimeria chalumnae61.390.0 597
LLPS-Php-2144Physcomitrella patens61.152e-113 346
LLPS-Mam-2332Macaca mulatta61.030.0 624
LLPS-Scp-1571Schizosaccharomyces pombe60.680.0 619
LLPS-Miv-1547Microbotryum violaceum59.813e-30 120
LLPS-Brn-2610Brassica napus59.666e-69 228
LLPS-Mua-2553Musa acuminata59.539e-61 204
LLPS-Cae-0621Caenorhabditis elegans58.970.0 565
LLPS-Tum-1249Tuber melanosporum58.447e-1889.0
LLPS-Cii-2318Ciona intestinalis58.370.0 563
LLPS-Orr-1377Oryza rufipogon58.065e-1269.7
LLPS-Pes-1473Pelodiscus sinensis57.80.0 572
LLPS-Cis-1512Ciona savignyi57.770.0 583