• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Brn-2610
BnaC04g22240D

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cytochrome c oxidase subunit 1
Gene Name: BnaC04g22240D, GSBRNA2T00075206001
Ensembl Gene: GSBRNA2T00156810001
Ensembl Protein: CDX93970
Organism: Brassica napus
Taxa ID: 3708
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
OthersPredicted from orthologs(View)

▼ FUNCTION

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCDX93970CDX93970
UniProtA0A078HXT5, A0A078HXT5_BRANA
GeneBankLK032531CDY42682.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKNLVRWLFS  TNHKDIGTLY  FIFDVIAGVM  GIHASQNLRT  YSFPPQILGG  FGNRFVPILI  60
61    GAPDMAFPRL  NNISFWLLPP  SLLLLLSSAL  VEVGSGTGWT  VYPPLSGITS  HSGGAVDLAI  120
121   FSLHLSGVSS  ILGSINFITT  IFNMRGPGMT  MHRLPLFVWS  VLVTAFLLLL  SLPVLAGAIT  180
181   MLLTDRNFNT  TFFDPAGGGD  PILYQHLFWF  FVISFLLFRE  NRSSGI  226
Nucleotide CDS Sequence (FASTA)
1     ATGAAAAATC  TGGTTCGATG  GCTGTTCTCC  ACAAACCACA  AGGATATAGG  GACTCTCTAT  60
61    TTCATTTTCG  ATGTCATTGC  TGGAGTGATG  GGCATACATG  CTTCTCAGAA  TCTCAGAACT  120
121   TATTCATTCC  CACCTCAAAT  TCTTGGTGGA  TTTGGTAATC  GGTTTGTTCC  GATTCTGATA  180
181   GGTGCACCTG  ACATGGCATT  TCCACGATTA  AATAATATTT  CATTCTGGTT  GTTGCCACCA  240
241   AGTCTCTTGC  TCCTATTAAG  CTCAGCCTTA  GTAGAAGTAG  GTAGCGGCAC  TGGGTGGACG  300
301   GTCTATCCGC  CCTTAAGTGG  TATTACCAGT  CATTCTGGAG  GAGCAGTTGA  TTTAGCAATT  360
361   TTTAGTCTTC  ATCTATCTGG  TGTTTCATCC  ATTTTAGGTT  CTATCAATTT  TATAACAACT  420
421   ATCTTCAACA  TGCGTGGACC  TGGAATGACT  ATGCATAGAT  TACCCCTATT  TGTGTGGTCC  480
481   GTTCTAGTGA  CAGCATTCCT  ACTTTTATTA  TCACTCCCGG  TACTGGCAGG  GGCAATTACC  540
541   ATGTTATTAA  CCGATCGAAA  CTTTAATACA  ACCTTTTTTG  ATCCCGCTGG  AGGGGGAGAC  600
601   CCAATTTTAT  ACCAGCATCT  CTTTTGGTTC  TTCGTCATAT  CGTTTCTACT  TTTTCGGGAA  660
661   AACCGGTCTT  CGGGTATCTA  G  681

▼ KEYWORD

ID
Family
Complete proteome
Copper
Electron transport
Heme
Iron
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Oxidoreductase
Reference proteome
Respiratory chain
Transmembrane
Transmembrane helix
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of membrane
Cellular Component
Mitochondrial inner membrane
Cellular Component
Respirasome
Molecular Function
Cytochrome-c oxidase activity
Molecular Function
Heme binding
Molecular Function
Metal ion binding
Biological Process
Aerobic respiration
Biological Process
Oxidative phosphorylation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sob-1598Sorghum bicolor100.02e-2395.1
LLPS-Ori-1667Oryza indica100.06e-68 221
LLPS-Amt-1584Amborella trichopoda96.771e-1268.9
LLPS-Nia-2569Nicotiana attenuata94.014e-74 239
LLPS-Sot-1594Solanum tuberosum94.012e-76 239
LLPS-Viv-2067Vitis vinifera92.423e-2089.7
LLPS-Sol-1807Solanum lycopersicum91.625e-71 230
LLPS-Dac-0545Daucus carota91.024e-69 226
LLPS-Glm-3014Glycine max90.325e-1161.2
LLPS-Miv-1547Microbotryum violaceum90.04e-1162.8
LLPS-Met-2377Medicago truncatula87.54e-1162.0
LLPS-Orbr-0672Oryza brachyantha81.254e-1058.5
LLPS-Art-3043Arabidopsis thaliana80.52e-95 295
LLPS-Zem-1415Zea mays80.082e-94 293
LLPS-Org-1946Oryza glaberrima80.081e-94 293
LLPS-Sei-0631Setaria italica80.083e-94 292
LLPS-Hov-0247Hordeum vulgare79.673e-94 292
LLPS-Tru-1823Triticum urartu79.254e-94 291
LLPS-Tra-2041Triticum aestivum79.255e-94 291
LLPS-Coc-2320Corchorus capsularis76.761e-86 271
LLPS-Gor-0296Gossypium raimondii76.351e-84 268
LLPS-Hea-2110Helianthus annuus74.694e-82 262
LLPS-Mua-2553Musa acuminata74.254e-57 186
LLPS-Pot-2137Populus trichocarpa72.59e-1161.2
LLPS-Orr-1377Oryza rufipogon69.233e-1164.3
LLPS-Cym-0896Cyanidioschyzon merolae66.532e-77 249
LLPS-Spr-1352Sporisorium reilianum65.972e-77 249
LLPS-Pap-3613Pan paniscus65.817e-74 239
LLPS-Hos-3951Homo sapiens65.818e-74 239
LLPS-Pat-2350Pan troglodytes65.381e-73 238
LLPS-Gog-4345Gorilla gorilla64.968e-74 239
LLPS-Rhb-1454Rhinopithecus bieti64.531e-73 238
LLPS-Poa-2054Pongo abelii64.533e-73 238
LLPS-Cap-1641Cavia porcellus64.533e-73 238
LLPS-Fud-1329Fukomys damarensis64.12e-73 238
LLPS-Mea-1548Mesocricetus auratus64.11e-73 238
LLPS-Mum-3502Mus musculus64.19e-74 239
LLPS-Maf-0678Macaca fascicularis64.17e-73 236
LLPS-Ora-3285Ornithorhynchus anatinus64.13e-73 238
LLPS-Ran-0050Rattus norvegicus64.17e-74 239
LLPS-Tut-1906Tursiops truncatus64.12e-72 235
LLPS-Orc-0500Oryctolagus cuniculus63.682e-73 238
LLPS-Fec-0793Felis catus63.685e-73 237
LLPS-Cas-2465Carlito syrichta63.685e-73 237
LLPS-Caf-3987Canis familiaris63.685e-73 237
LLPS-Chs-3275Chlorocebus sabaeus63.681e-73 238
LLPS-Ova-2685Ovis aries63.686e-73 236
LLPS-Aim-2252Ailuropoda melanoleuca63.689e-73 236
LLPS-Lac-4021Latimeria chalumnae63.561e-71 233
LLPS-Urm-2682Ursus maritimus63.259e-73 236
LLPS-Mod-2996Monodelphis domestica63.257e-73 236
LLPS-Ict-1728Ictidomys tridecemlineatus63.253e-72 235
LLPS-Mam-2332Macaca mulatta63.255e-72 234
LLPS-Sus-3456Sus scrofa63.251e-72 236
LLPS-Mal-3599Mandrillus leucophaeus63.254e-72 234
LLPS-Scf-2556Scleropages formosus62.872e-71 233
LLPS-Fia-2249Ficedula albicollis62.828e-72 234
LLPS-Drm-1685Drosophila melanogaster62.821e-72 236
LLPS-Sah-3878Sarcophilus harrisii62.711e-73 238
LLPS-Eqc-3649Equus caballus62.395e-72 234
LLPS-Ere-0617Erinaceus europaeus62.391e-71 233
LLPS-Meg-2700Meleagris gallopavo62.344e-72 234
LLPS-Anc-2465Anolis carolinensis62.291e-70 230
LLPS-Nec-1255Neurospora crassa62.137e-69 227
LLPS-Loa-1514Loxodonta africana61.972e-71 233
LLPS-Gaga-1222Gallus gallus61.921e-69 228
LLPS-Tag-2443Taeniopygia guttata61.924e-72 234
LLPS-Xet-0613Xenopus tropicalis61.865e-72 234
LLPS-Ten-2621Tetraodon nigroviridis61.861e-71 233
LLPS-Orl-3238Oryzias latipes61.861e-71 233
LLPS-Gaa-1100Gasterosteus aculeatus61.866e-72 234
LLPS-Dar-3194Danio rerio61.63e-70 229
LLPS-Icp-3033Ictalurus punctatus61.61e-71 233
LLPS-Xim-3760Xiphophorus maculatus61.542e-70 230
LLPS-Tar-2687Takifugu rubripes61.442e-71 233
LLPS-Leo-1781Lepisosteus oculatus61.029e-71 231
LLPS-Cogr-1582Colletotrichum graminicola59.662e-68 225
LLPS-Cii-2318Ciona intestinalis59.075e-65 216
LLPS-Asg-0401Ashbya gossypii57.563e-68 225
LLPS-Cis-1512Ciona savignyi57.323e-63 211
LLPS-Phn-0837Phaeosphaeria nodorum56.174e-61 209
LLPS-Sac-1005Saccharomyces cerevisiae55.937e-66 218
LLPS-Cae-0621Caenorhabditis elegans54.242e-58 199
LLPS-Pes-1473Pelodiscus sinensis54.25e-62 208
LLPS-Scp-1571Schizosaccharomyces pombe53.394e-59 201
LLPS-Lem-1154Leptosphaeria maculans47.963e-1574.7