DrLLPS - Data resource of LLPS

LLPS-Chr-0124
RPA12

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	DNA-directed RNA polymerase subunit
Gene Name:	RPA12, CHLRE_01g018000v5, CHLREDRAFT_183563
Ensembl Gene:	CHLRE_01g018000v5
Ensembl Protein:	PNW88184
Organism:	Chlamydomonas reinhardtii
Taxa ID:	3055
LLPS Type:	LLPS regulator

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, P-body	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Caenorhabditis elegans	LLPS-Cae-0268	O17587	Regulator	P-body	35.83	2e-09	55.8
Mus musculus	LLPS-Mum-0679	Q791N7	Client	Nucleolus	36.94	5e-13	65.9
Homo sapiens	LLPS-Hos-0365	Q9P1U0	Client	Nucleolus	34.78	4e-12	63.5
Arabidopsis thaliana	LLPS-Art-1071	Q9LU97	Client	Nucleolus	81.66	0.0	808

▼ FUNCTION

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	PNW88184	PNW88184
UniProt		A8HPP5, A8HPP5_CHLRE
GeneBank	CM008962, DS496108	PNW88184.1, EDP09671.1
RefSeq	XM_001689881.1	XP_001689933.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSSDKDWMFC PTSGYLLHLD PKRQVAACPV SGYERSLAEL SSVKVVLRTD MEDYRRRFAL 60 61 EPLVKSVEDE ELLKGRKRAT VDEPCPKCNH RQLEYYTMQL RSADEGQTVF YECKNCGHKY 120 121 SQNT 124
Nucleotide CDS Sequence (FASTA)
1 ATGTCGTCGG ACAAGGACTG GATGTTCTGC CCCACGTCGG GGTACCTGCT GCACCTCGAC 60 61 CCCAAGCGGC AAGTGGCCGC TTGCCCCGTG TCGGGCTACG AGCGCAGCCT GGCGGAGTTA 120 121 TCATCCGTGA AAGTGGTTCT ACGCACGGAC ATGGAGGACT ACCGGCGCCG TTTTGCGCTT 180 181 GAGCCGCTGG TGAAGAGCGT GGAGGATGAG GAGCTGCTGA AGGGCCGCAA GCGCGCCACG 240 241 GTGGACGAGC CCTGCCCCAA GTGCAACCAC CGTCAGCTGG AGTACTACAC CATGCAGCTG 300 301 CGCTCGGCGG ATGAGGGCCA GACCGTCTTC TACGAGTGCA AGAACTGCGG GCATAAGTAT 360 361 TCTCAGAACA CGTGA 375

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0240	DNA-directed RNA polymerase
KW-0479	Metal-binding
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0804	Transcription
KW-0862	Zinc
KW-0863	Zinc-finger

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005736	Cellular Component	RNA polymerase I complex
GO:0003899	Molecular Function	DNA-directed 5'-3' RNA polymerase activity
GO:0003676	Molecular Function	Nucleic acid binding
GO:0008270	Molecular Function	Zinc ion binding
GO:0006379	Biological Process	MRNA cleavage
GO:0006363	Biological Process	Termination of RNA polymerase I transcription

▼ KEGG

cre:CHLREDRAFT_183563

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Sem-2129	Selaginella moellendorffii	73.47	7e-18	78.6
LLPS-Pug-0009	Puccinia graminis	68.18	1e-15	72.8
LLPS-Drm-0910	Drosophila melanogaster	57.78	5e-11	60.1
LLPS-Gas-0079	Galdieria sulphuraria	57.45	5e-11	60.8
LLPS-Urm-0429	Ursus maritimus	56.76	2e-08	52.8
LLPS-Fud-0016	Fukomys damarensis	55.0	1e-08	53.5
LLPS-Amt-1274	Amborella trichopoda	52.81	2e-22	90.5
LLPS-Usm-0925	Ustilago maydis	52.78	1e-06	49.7
LLPS-Spr-1348	Sporisorium reilianum	52.78	2e-06	49.3
LLPS-Poa-4532	Pongo abelii	50.0	9e-06	44.7
LLPS-Mod-3834	Monodelphis domestica	48.84	3e-06	49.3
LLPS-Prp-2409	Prunus persica	47.62	2e-06	47.0
LLPS-Php-0360	Physcomitrella patens	46.43	3e-18	80.9
LLPS-Mua-0072	Musa acuminata	45.97	1e-29	109
LLPS-Mao-1289	Magnaporthe oryzae	45.45	7e-07	48.5
LLPS-Orbr-0679	Oryza brachyantha	42.62	9e-28	104
LLPS-Brd-0507	Brachypodium distachyon	42.5	7e-27	102
LLPS-Osl-0301	Ostreococcus lucimarinus	41.67	3e-20	85.5
LLPS-Cap-4319	Cavia porcellus	41.54	1e-06	47.4
LLPS-Mam-4595	Macaca mulatta	41.54	1e-06	47.4
LLPS-Nol-2139	Nomascus leucogenys	41.54	1e-06	47.4
LLPS-Ict-4632	Ictidomys tridecemlineatus	41.54	1e-06	47.4
LLPS-Pap-1529	Pan paniscus	41.54	1e-06	47.4
LLPS-Pat-0056	Pan troglodytes	41.54	1e-06	47.4
LLPS-Otg-1787	Otolemur garnettii	41.54	1e-06	47.4
LLPS-Rhb-3705	Rhinopithecus bieti	41.54	1e-06	47.4
LLPS-Tut-2432	Tursiops truncatus	41.54	1e-06	47.4
LLPS-Bot-4673	Bos taurus	41.54	1e-06	47.4
LLPS-Ran-2976	Rattus norvegicus	41.54	1e-06	47.4
LLPS-Paa-3767	Papio anubis	41.54	1e-06	47.4
LLPS-Myl-4342	Myotis lucifugus	41.54	1e-06	47.4
LLPS-Mum-4923	Mus musculus	41.54	1e-06	47.4
LLPS-Maf-4678	Macaca fascicularis	41.54	1e-06	47.4
LLPS-Mea-3991	Mesocricetus auratus	41.54	1e-06	47.4
LLPS-Chs-0174	Chlorocebus sabaeus	41.54	1e-06	47.4
LLPS-Sus-2520	Sus scrofa	41.54	1e-06	47.4
LLPS-Cea-3977	Cercocebus atys	41.54	1e-06	47.4
LLPS-Aon-4787	Aotus nancymaae	41.54	1e-06	47.4
LLPS-Gog-0955	Gorilla gorilla	41.54	1e-06	47.4
LLPS-Caj-4162	Callithrix jacchus	41.54	1e-06	47.4
LLPS-Viv-0152	Vitis vinifera	41.35	2e-17	77.8
LLPS-Orr-0397	Oryza rufipogon	40.98	3e-26	100
LLPS-Ors-0757	Oryza sativa	40.98	3e-26	100
LLPS-Orp-0831	Oryza punctata	40.98	3e-26	100
LLPS-Gag-0772	Gaeumannomyces graminis	40.91	1e-06	47.0
LLPS-Tra-0263	Triticum aestivum	40.83	6e-28	105
LLPS-Beb-0224	Beauveria bassiana	40.43	5e-06	45.8
LLPS-Cym-0287	Cyanidioschyzon merolae	40.26	8e-10	57.0
LLPS-Orgl-0333	Oryza glumaepatula	40.16	3e-25	98.6
LLPS-Orb-1029	Oryza barthii	40.16	3e-25	98.6
LLPS-Orni-0124	Oryza nivara	40.16	3e-25	98.6
LLPS-Eqc-2533	Equus caballus	40.0	5e-06	45.8
LLPS-Orc-3132	Oryctolagus cuniculus	40.0	5e-06	45.8
LLPS-Mal-1254	Mandrillus leucophaeus	40.0	3e-06	46.6
LLPS-Ova-0011	Ovis aries	40.0	4e-06	46.2
LLPS-Aim-1058	Ailuropoda melanoleuca	40.0	5e-06	45.8
LLPS-Sei-0182	Setaria italica	39.5	4e-23	92.8
LLPS-Yal-0360	Yarrowia lipolytica	37.88	4e-06	48.5
LLPS-Ori-0215	Oryza indica	37.5	1e-21	89.7
LLPS-Pyt-0039	Pyrenophora teres	37.3	3e-16	74.3
LLPS-Asg-0443	Ashbya gossypii	37.21	2e-16	75.1
LLPS-Sac-1076	Saccharomyces cerevisiae	36.92	1e-14	70.5
LLPS-Crn-0349	Cryptococcus neoformans	36.51	4e-13	66.6
LLPS-Lem-0552	Leptosphaeria maculans	36.22	9e-14	67.8
LLPS-Cae-0268	Caenorhabditis elegans	35.83	2e-09	55.8
LLPS-Thc-1753	Theobroma cacao	35.77	1e-16	75.5
LLPS-Pytr-0670	Pyrenophora triticirepentis	35.59	2e-14	70.1
LLPS-Org-1417	Oryza glaberrima	35.53	2e-20	86.7
LLPS-Zem-1543	Zea mays	35.34	9e-20	83.6
LLPS-Glm-1676	Glycine max	35.25	4e-19	82.0
LLPS-Dar-0889	Danio rerio	35.04	5e-13	66.2
LLPS-Bro-0528	Brassica oleracea	34.96	5e-17	76.6
LLPS-Brr-0814	Brassica rapa	34.96	3e-17	77.0
LLPS-Brn-2201	Brassica napus	34.96	3e-17	77.0
LLPS-Hos-0365	Homo sapiens	34.78	4e-12	63.5
LLPS-Man-0731	Macaca nemestrina	34.78	3e-12	63.9
LLPS-Sah-0333	Sarcophilus harrisii	34.58	4e-11	60.8
LLPS-Kop-0780	Komagataella pastoris	34.4	1e-14	70.5
LLPS-Loa-1207	Loxodonta africana	34.23	2e-12	64.3
LLPS-Scf-0896	Scleropages formosus	34.23	3e-10	58.2
LLPS-Put-0231	Puccinia triticina	34.19	2e-12	64.7
LLPS-Scc-1297	Schizosaccharomyces cryophilus	34.15	1e-16	75.9
LLPS-Caf-0057	Canis familiaris	33.93	6e-11	60.1
LLPS-Cas-2272	Carlito syrichta	33.91	4e-13	66.2
LLPS-Ten-1635	Tetraodon nigroviridis	33.88	3e-11	60.8
LLPS-Gaa-0334	Gasterosteus aculeatus	33.87	4e-10	57.8
LLPS-Ved-0586	Verticillium dahliae	33.86	2e-13	67.0
LLPS-Coo-0186	Colletotrichum orbiculare	33.86	2e-14	69.7
LLPS-Abg-0578	Absidia glauca	33.73	2e-07	49.3
LLPS-Phv-0347	Phaseolus vulgaris	33.61	8e-18	78.6
LLPS-Sol-1508	Solanum lycopersicum	33.61	4e-09	54.7
LLPS-Hea-0454	Helianthus annuus	33.61	8e-18	80.1
LLPS-Fec-2035	Felis catus	33.33	2e-10	58.5
LLPS-Gor-1929	Gossypium raimondii	33.33	2e-13	67.4
LLPS-Asn-0562	Aspergillus nidulans	33.33	1e-10	59.3
LLPS-Dac-0245	Daucus carota	33.33	2e-18	80.5
LLPS-Pot-0255	Populus trichocarpa	33.06	1e-06	47.8
LLPS-Cii-1170	Ciona intestinalis	33.06	7e-10	57.0
LLPS-Cis-1188	Ciona savignyi	33.06	3e-10	58.2
LLPS-Dio-2395	Dipodomys ordii	33.04	1e-10	59.3
LLPS-Ere-0088	Erinaceus europaeus	33.04	2e-12	64.7
LLPS-Fus-0752	Fusarium solani	32.84	4e-06	46.6
LLPS-Orm-0904	Oryza meridionalis	32.79	3e-13	66.2
LLPS-Gaga-1358	Gallus gallus	32.79	4e-08	52.0
LLPS-Arl-1372	Arabidopsis lyrata	32.79	6e-16	73.6
LLPS-Tar-0795	Takifugu rubripes	32.76	2e-12	64.3
LLPS-Hov-0649	Hordeum vulgare	32.73	4e-21	88.6
LLPS-Nia-0934	Nicotiana attenuata	32.5	3e-16	74.7
LLPS-Orl-2222	Oryzias latipes	32.48	3e-08	52.4
LLPS-Cogr-1224	Colletotrichum graminicola	32.28	4e-13	66.2
LLPS-Asm-3137	Astyanax mexicanus	32.26	4e-12	63.2
LLPS-Fia-3276	Ficedula albicollis	32.23	2e-07	49.7
LLPS-Cus-0359	Cucumis sativus	32.0	6e-11	60.1
LLPS-Asni-1168	Aspergillus niger	32.0	1e-09	56.2
LLPS-Art-1071	Arabidopsis thaliana	31.97	5e-15	71.2
LLPS-Sob-0125	Sorghum bicolor	31.93	8e-17	75.9
LLPS-Scp-0365	Schizosaccharomyces pombe	31.71	2e-14	69.7
LLPS-Sot-0996	Solanum tuberosum	31.71	5e-09	54.3
LLPS-Scj-1184	Schizosaccharomyces japonicus	31.71	3e-13	66.6
LLPS-Mae-0332	Manihot esculenta	31.62	2e-16	75.1
LLPS-Trv-1230	Trichoderma virens	31.5	2e-10	58.9
LLPS-Trr-1497	Trichoderma reesei	31.5	4e-10	57.8
LLPS-Mel-0348	Melampsora laricipopulina	31.43	1e-16	76.3
LLPS-Lac-3987	Latimeria chalumnae	31.4	2e-06	47.0
LLPS-Met-0957	Medicago truncatula	31.36	2e-10	58.5
LLPS-Asc-0183	Aspergillus clavatus	31.2	3e-08	52.8
LLPS-Asfu-0306	Aspergillus fumigatus	31.11	1e-07	50.8
LLPS-Icp-1193	Ictalurus punctatus	30.83	5e-11	60.5
LLPS-Mup-0417	Mustela putorius furo	30.77	2e-10	58.5
LLPS-Xet-3849	Xenopus tropicalis	30.58	3e-06	46.6
LLPS-Scm-3466	Scophthalmus maximus	30.58	2e-06	47.0
LLPS-Cog-0820	Colletotrichum gloeosporioides	30.4	2e-10	58.9
LLPS-Anc-2604	Anolis carolinensis	30.09	3e-09	55.1
LLPS-Dos-0824	Dothistroma septosporum	30.08	2e-11	61.6
LLPS-Pof-3455	Poecilia formosa	29.75	2e-06	46.6
LLPS-Orn-0085	Oreochromis niloticus	29.75	2e-06	47.0
LLPS-Xim-1962	Xiphophorus maculatus	29.75	2e-06	47.0
LLPS-Leo-3880	Lepisosteus oculatus	29.75	2e-06	46.6
LLPS-Aso-0036	Aspergillus oryzae	29.46	9e-09	53.9
LLPS-Asf-0112	Aspergillus flavus	29.46	9e-09	53.9
LLPS-Pes-2741	Pelodiscus sinensis	29.41	9e-10	57.0
LLPS-Map-0014	Magnaporthe poae	28.7	9e-08	50.8

LLPS-Chr-0124RPA12

Protein Sequence

Nucleotide Sequence

LLPS-Chr-0124
RPA12