DrLLPS - Data resource of LLPS

LLPS-Aon-4787
POLR3K

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	DNA-directed RNA polymerase subunit
Gene Name:	POLR3K
Ensembl Gene:	ENSANAG00000024313.1
Ensembl Protein:	ENSANAP00000012761.1
Organism:	Aotus nancymaae
Taxa ID:	37293
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0107	Q04307	Client	Stress granule	52.21	3e-28	105

▼ FUNCTION

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSANAT00000030582.1	ENSANAP00000012761.1
UniProt		A0A2K5CVN9, A0A2K5CVN9_AOTNA
RefSeq	XM_012468736.1	XP_012324159.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MLLFCPGCGN GLIVEEGQRC HRFACNTCPY VHNITRKVTN RKYPKLKEVD DVLGGAAAWE 60 61 NVDSTAEPCP KCEHPRAYFM QLQTRSADEP MTTFYKCCNA QCGHRWRD 108
Nucleotide CDS Sequence (FASTA)
1 ATGCTGCTGT TCTGCCCCGG CTGCGGGAAC GGGCTGATCG TGGAGGAGGG ACAGCGCTGC 60 61 CACCGCTTCG CCTGCAATAC GTGCCCCTAC GTGCACAACA TCACCCGCAA GGTAACAAAT 120 121 CGGAAGTACC CAAAACTGAA AGAAGTAGAT GATGTGCTCG GTGGAGCAGC TGCCTGGGAG 180 181 AATGTTGACT CTACTGCAGA GCCCTGTCCC AAATGCGAAC ATCCTCGGGC CTACTTCATG 240 241 CAGCTTCAGA CCCGCTCTGC AGACGAGCCC ATGACCACCT TCTACAAGTG CTGCAATGCC 300 301 CAGTGTGGAC ACCGCTGGAG GGATTAG 327

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0240	DNA-directed RNA polymerase
KW-0479	Metal-binding
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0804	Transcription
KW-0862	Zinc
KW-0863	Zinc-finger

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005730	Cellular Component	Nucleolus
GO:0003899	Molecular Function	DNA-directed 5'-3' RNA polymerase activity
GO:0003676	Molecular Function	Nucleic acid binding
GO:0008270	Molecular Function	Zinc ion binding
GO:0006351	Biological Process	Transcription, DNA-templated
GO:0042779	Biological Process	TRNA 3'-trailer cleavage

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Rhb-3705	Rhinopithecus bieti	100.0	1e-77	231
LLPS-Pat-0056	Pan troglodytes	100.0	1e-77	231
LLPS-Pap-1529	Pan paniscus	100.0	1e-77	231
LLPS-Nol-2139	Nomascus leucogenys	100.0	1e-77	231
LLPS-Mam-4595	Macaca mulatta	100.0	1e-77	231
LLPS-Caj-4162	Callithrix jacchus	100.0	1e-77	231
LLPS-Gog-0955	Gorilla gorilla	100.0	1e-77	231
LLPS-Cea-3977	Cercocebus atys	100.0	1e-77	231
LLPS-Sus-2520	Sus scrofa	100.0	1e-77	231
LLPS-Maf-4678	Macaca fascicularis	100.0	1e-77	231
LLPS-Mum-4923	Mus musculus	100.0	1e-77	231
LLPS-Chs-0174	Chlorocebus sabaeus	100.0	1e-77	231
LLPS-Paa-3767	Papio anubis	100.0	1e-77	231
LLPS-Myl-4342	Myotis lucifugus	100.0	1e-77	231
LLPS-Ran-2976	Rattus norvegicus	100.0	1e-77	231
LLPS-Dio-3654	Dipodomys ordii	100.0	2e-42	140
LLPS-Otg-1787	Otolemur garnettii	99.07	8e-77	228
LLPS-Hos-3865	Homo sapiens	99.07	9e-77	228
LLPS-Fec-0027	Felis catus	99.07	9e-77	228
LLPS-Ict-4632	Ictidomys tridecemlineatus	99.07	2e-77	230
LLPS-Caf-3413	Canis familiaris	99.07	9e-77	228
LLPS-Eqc-2533	Equus caballus	99.07	6e-77	229
LLPS-Cap-4319	Cavia porcellus	99.07	3e-77	229
LLPS-Mea-3991	Mesocricetus auratus	99.07	7e-77	229
LLPS-Mal-1254	Mandrillus leucophaeus	99.07	3e-77	229
LLPS-Aim-1058	Ailuropoda melanoleuca	99.07	6e-77	229
LLPS-Bot-4673	Bos taurus	99.07	2e-77	230
LLPS-Tut-2432	Tursiops truncatus	99.07	2e-77	230
LLPS-Mod-3834	Monodelphis domestica	98.61	6e-44	157
LLPS-Orc-3132	Oryctolagus cuniculus	98.15	4e-76	227
LLPS-Loa-3720	Loxodonta africana	98.15	9e-76	226
LLPS-Fud-0358	Fukomys damarensis	98.15	1e-76	228
LLPS-Ova-0011	Ovis aries	97.2	5e-75	224
LLPS-Ere-0422	Erinaceus europaeus	96.97	5e-41	136
LLPS-Pof-3455	Poecilia formosa	94.44	3e-72	217
LLPS-Xim-1962	Xiphophorus maculatus	94.44	2e-72	217
LLPS-Dar-1095	Danio rerio	93.52	3e-72	217
LLPS-Ten-2094	Tetraodon nigroviridis	93.52	5e-72	216
LLPS-Scf-3035	Scleropages formosus	93.52	2e-72	218
LLPS-Orn-0085	Oreochromis niloticus	92.59	6e-71	214
LLPS-Tar-3823	Takifugu rubripes	92.59	8e-71	213
LLPS-Icp-4043	Ictalurus punctatus	91.67	1e-71	215
LLPS-Leo-3880	Lepisosteus oculatus	91.67	3e-71	214
LLPS-Asm-0772	Astyanax mexicanus	90.74	7e-71	213
LLPS-Orl-0436	Oryzias latipes	90.74	1e-69	210
LLPS-Ora-2590	Ornithorhynchus anatinus	90.28	7e-43	141
LLPS-Lac-3987	Latimeria chalumnae	89.81	4e-69	209
LLPS-Xet-3849	Xenopus tropicalis	89.81	2e-70	213
LLPS-Gaa-3900	Gasterosteus aculeatus	89.81	6e-68	206
LLPS-Pes-3643	Pelodiscus sinensis	88.89	5e-63	193
LLPS-Scm-3466	Scophthalmus maximus	88.89	3e-67	204
LLPS-Gaga-1358	Gallus gallus	88.89	4e-70	212
LLPS-Fia-3276	Ficedula albicollis	87.85	4e-68	207
LLPS-Anc-2260	Anolis carolinensis	84.85	7e-36	123
LLPS-Man-2498	Macaca nemestrina	81.48	1e-57	180
LLPS-Cis-1188	Ciona savignyi	79.63	7e-62	191
LLPS-Cas-0016	Carlito syrichta	77.78	5e-54	171
LLPS-Cii-1170	Ciona intestinalis	76.85	5e-60	186
LLPS-Poa-4532	Pongo abelii	72.22	1e-47	153
LLPS-Drm-1193	Drosophila melanogaster	70.37	1e-54	172
LLPS-Cae-1738	Caenorhabditis elegans	61.11	3e-44	145
LLPS-Abg-0909	Absidia glauca	58.0	2e-33	118
LLPS-Php-2030	Physcomitrella patens	57.94	6e-37	127
LLPS-Mel-1380	Melampsora laricipopulina	56.73	1e-38	132
LLPS-Chr-1357	Chlamydomonas reinhardtii	56.41	1e-07	52.4
LLPS-Crn-0550	Cryptococcus neoformans	55.86	4e-36	125
LLPS-Pytr-0419	Pyrenophora triticirepentis	55.56	1e-24	95.9
LLPS-Spr-0783	Sporisorium reilianum	55.56	2e-40	136
LLPS-Usm-1139	Ustilago maydis	55.56	7e-41	137
LLPS-Pyt-0402	Pyrenophora teres	55.56	6e-25	96.7
LLPS-Lem-0347	Leptosphaeria maculans	54.74	4e-26	99.4
LLPS-Kop-1348	Komagataella pastoris	54.46	3e-31	112
LLPS-Asg-0117	Ashbya gossypii	53.1	7e-30	109
LLPS-Sem-1556	Selaginella moellendorffii	52.38	4e-33	117
LLPS-Sac-0107	Saccharomyces cerevisiae	52.21	2e-28	105
LLPS-Tum-1406	Tuber melanosporum	51.79	2e-30	110
LLPS-Dos-1369	Dothistroma septosporum	50.98	1e-07	52.4
LLPS-Miv-1027	Microbotryum violaceum	50.93	3e-33	117
LLPS-Coo-0588	Colletotrichum orbiculare	50.89	3e-28	105
LLPS-Cogr-0149	Colletotrichum graminicola	50.0	1e-24	95.5
LLPS-Phn-1020	Phaeosphaeria nodorum	50.0	2e-29	108
LLPS-Scp-1643	Schizosaccharomyces pombe	50.0	2e-25	97.8
LLPS-Asc-0650	Aspergillus clavatus	49.57	4e-29	107
LLPS-Trr-1354	Trichoderma reesei	49.55	5e-28	104
LLPS-Beb-0224	Beauveria bassiana	49.55	1e-27	103
LLPS-Trv-1281	Trichoderma virens	49.55	5e-28	104
LLPS-Fuo-0976	Fusarium oxysporum	49.55	9e-28	103
LLPS-Cym-0285	Cyanidioschyzon merolae	49.12	2e-08	54.3
LLPS-Cog-0683	Colletotrichum gloeosporioides	49.11	9e-24	93.6
LLPS-Mua-1037	Musa acuminata	49.09	1e-29	108
LLPS-Scj-1593	Schizosaccharomyces japonicus	49.09	5e-27	102
LLPS-Asfu-1388	Aspergillus fumigatus	48.72	2e-28	105
LLPS-Mao-0037	Magnaporthe oryzae	48.67	8e-26	99.0
LLPS-Yal-1321	Yarrowia lipolytica	48.65	2e-25	97.4
LLPS-Blg-0919	Blumeria graminis	48.28	7e-28	104
LLPS-Nef-1657	Neosartorya fischeri	47.41	4e-26	99.8
LLPS-Nec-0992	Neurospora crassa	47.27	7e-25	96.3
LLPS-Map-0522	Magnaporthe poae	46.9	6e-25	96.7
LLPS-Orbr-1137	Oryza brachyantha	46.73	9e-26	98.6
LLPS-Ved-1502	Verticillium dahliae	46.6	3e-20	84.3
LLPS-Scc-1482	Schizosaccharomyces cryophilus	46.43	2e-24	95.1
LLPS-Fus-0752	Fusarium solani	46.36	3e-24	95.1
LLPS-Asn-0346	Aspergillus nidulans	46.15	3e-21	87.0
LLPS-Sei-0593	Setaria italica	45.79	1e-25	98.6
LLPS-Asni-0972	Aspergillus niger	45.69	4e-25	97.1
LLPS-Asf-0835	Aspergillus flavus	45.69	2e-25	98.2
LLPS-Aso-1260	Aspergillus oryzae	45.69	2e-25	98.2
LLPS-Osl-1214	Ostreococcus lucimarinus	45.45	6e-31	112
LLPS-Gas-0170	Galdieria sulphuraria	45.37	3e-29	107
LLPS-Viv-1962	Vitis vinifera	45.05	1e-20	85.5
LLPS-Orp-0606	Oryza punctata	44.95	2e-23	92.4
LLPS-Dac-1902	Daucus carota	44.95	1e-19	89.0
LLPS-Orr-0491	Oryza rufipogon	44.86	3e-22	92.4
LLPS-Thc-1138	Theobroma cacao	44.07	5e-17	75.9
LLPS-Orm-0337	Oryza meridionalis	44.04	3e-23	92.0
LLPS-Orni-1376	Oryza nivara	44.04	3e-23	92.0
LLPS-Orb-2108	Oryza barthii	44.04	3e-23	92.0
LLPS-Ori-2227	Oryza indica	44.04	3e-23	92.0
LLPS-Zyt-0866	Zymoseptoria tritici	43.7	7e-25	97.4
LLPS-Nia-2036	Nicotiana attenuata	43.52	9e-20	83.2
LLPS-Sob-0251	Sorghum bicolor	42.99	2e-24	95.5
LLPS-Zem-1490	Zea mays	42.99	3e-23	92.4
LLPS-Art-2620	Arabidopsis thaliana	42.73	3e-20	84.3
LLPS-Gor-1852	Gossypium raimondii	42.34	7e-18	78.2
LLPS-Glm-2146	Glycine max	42.34	4e-19	81.6
LLPS-Phv-0759	Phaseolus vulgaris	42.2	3e-19	81.6
LLPS-Ors-2052	Oryza sativa	42.2	2e-24	95.1
LLPS-Org-1377	Oryza glaberrima	42.2	2e-24	95.1
LLPS-Amt-2016	Amborella trichopoda	42.06	6e-24	94.0
LLPS-Coc-1705	Corchorus capsularis	41.44	4e-17	76.3
LLPS-Sot-0996	Solanum tuberosum	41.12	7e-19	80.9
LLPS-Mae-1187	Manihot esculenta	40.91	3e-16	73.9
LLPS-Prp-2409	Prunus persica	40.91	3e-18	79.3
LLPS-Sol-1508	Solanum lycopersicum	40.91	9e-20	83.2
LLPS-Arl-1571	Arabidopsis lyrata	40.91	7e-19	80.5
LLPS-Pot-0255	Populus trichocarpa	40.54	9e-18	77.8
LLPS-Cus-2007	Cucumis sativus	40.54	4e-19	81.3
LLPS-Bro-0922	Brassica oleracea	40.37	8e-18	77.8
LLPS-Brn-2317	Brassica napus	40.37	8e-18	77.8
LLPS-Met-0957	Medicago truncatula	39.82	4e-22	89.7
LLPS-Hea-1923	Helianthus annuus	39.64	5e-15	71.6
LLPS-Brr-2329	Brassica rapa	39.45	1e-16	75.1
LLPS-Scs-0525	Sclerotinia sclerotiorum	37.9	1e-18	80.1
LLPS-Orgl-2302	Oryza glumaepatula	35.66	2e-19	82.8
LLPS-Brd-1050	Brachypodium distachyon	33.93	4e-08	51.6
LLPS-Tra-2264	Triticum aestivum	33.93	4e-08	51.6
LLPS-Via-1438	Vigna angularis	33.93	6e-08	51.2
LLPS-Pug-0009	Puccinia graminis	31.15	7e-08	50.8
LLPS-Urm-2744	Ursus maritimus	27.68	4e-08	51.6
LLPS-Meg-3010	Meleagris gallopavo	27.68	4e-08	51.6
LLPS-Mup-1409	Mustela putorius furo	27.68	4e-08	51.6

LLPS-Aon-4787POLR3K

Protein Sequence

Nucleotide Sequence

LLPS-Aon-4787
POLR3K