• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Scc-1297
SPOG_05431

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: DNA-directed RNA polymerase subunit
Gene Name: SPOG_05431
Ensembl Gene: SPOG_05431
Ensembl Protein: EPY49729
Organism: Schizosaccharomyces cryophilus
Taxa ID: 653667
LLPS Type: LLPS regulator


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-bodyPredicted from orthologs(View)

▼ FUNCTION


DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblEPY49729EPY49729
UniProtS9VU67, S9VU67_SCHCR
GeneBankKE546994EPY49729.1
RefSeqXM_013170005.1XP_013025459.1

▼ SEQUENCE


Protein Sequence (FASTA)
1     MSAIGSLVFC  SECGNLLEST  TAQWTTCDQC  QSVYPSSQFA  NLAVETKSGP  NAFPSALKLK  60
61    HSIVQVETQK  EEAATIDEKC  PKCGNDQMTF  HTLQLRSADE  GSTVFYECPR  CGYKFSTNN  119
Nucleotide CDS Sequence (FASTA)
1     ATGTCAGCCA  TTGGATCCTT  GGTTTTTTGC  TCTGAATGCG  GAAATCTTTT  AGAAAGTACT  60
61    ACGGCACAAT  GGACCACATG  TGATCAATGT  CAATCTGTTT  ATCCATCTTC  GCAATTTGCA  120
121   AATTTGGCTG  TTGAAACGAA  AAGTGGACCC  AATGCTTTTC  CTTCTGCTCT  GAAATTAAAA  180
181   CATAGTATTG  TCCAAGTGGA  AACACAAAAG  GAGGAAGCTG  CGACGATTGA  CGAAAAGTGT  240
241   CCTAAGTGTG  GTAACGATCA  GATGACTTTC  CATACCTTGC  AATTACGAAG  TGCCGATGAA  300
301   GGTTCCACTG  TCTTTTATGA  ATGTCCTAGG  TGTGGTTACA  AATTCAGCAC  GAATAATTAA  360

▼ KEYWORD


ID
Family
Complete proteome
DNA-directed RNA polymerase
Metal-binding
Nucleus
Reference proteome
Transcription
Zinc
Zinc-finger

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
RNA polymerase I complex
Molecular Function
Nucleic acid binding
Molecular Function
RNA polymerase I activity
Molecular Function
RNA polymerase II-specific DNA-binding transcription factor binding
Molecular Function
Zinc ion binding
Biological Process
MRNA cleavage
Biological Process
Negative regulation of transcription by RNA polymerase II
Biological Process
Nucleolar large rRNA transcription by RNA polymerase I
Biological Process
Termination of RNA polymerase I transcription

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Scp-0365Schizosaccharomyces pombe91.61e-77 232
LLPS-Scj-1184Schizosaccharomyces japonicus83.331e-69 211
LLPS-Amt-1274Amborella trichopoda59.571e-1469.7
LLPS-Abg-0578Absidia glauca56.412e-2289.7
LLPS-Kop-0780Komagataella pastoris56.11e-45 150
LLPS-Sac-1076Saccharomyces cerevisiae56.02e-45 150
LLPS-Yal-0432Yarrowia lipolytica54.841e-44 147
LLPS-Hov-0649Hordeum vulgare54.766e-1160.5
LLPS-Spr-0093Sporisorium reilianum53.283e-39 134
LLPS-Usm-0610Ustilago maydis53.283e-39 134
LLPS-Asg-0443Ashbya gossypii52.84e-41 139
LLPS-Put-0231Puccinia triticina50.432e-29 109
LLPS-Asn-0562Aspergillus nidulans50.01e-30 111
LLPS-Asfu-0306Aspergillus fumigatus50.02e-28 106
LLPS-Pug-0009Puccinia graminis49.614e-33 118
LLPS-Asc-0183Aspergillus clavatus49.591e-27 104
LLPS-Mel-0348Melampsora laricipopulina48.945e-35 124
LLPS-Lem-0552Leptosphaeria maculans48.361e-27 103
LLPS-Cym-0287Cyanidioschyzon merolae47.628e-0851.2
LLPS-Met-0957Medicago truncatula47.627e-0645.4
LLPS-Asni-1168Aspergillus niger47.581e-26 101
LLPS-Pyt-0039Pyrenophora teres47.582e-28 106
LLPS-Coo-0186Colletotrichum orbiculare46.772e-27 103
LLPS-Dos-0824Dothistroma septosporum46.771e-31 114
LLPS-Gag-0772Gaeumannomyces graminis46.671e-0750.1
LLPS-Urm-0429Ursus maritimus46.514e-0955.1
LLPS-Crn-0349Cryptococcus neoformans46.344e-29 108
LLPS-Trv-1230Trichoderma virens45.971e-2394.0
LLPS-Pytr-0670Pyrenophora triticirepentis45.835e-2598.2
LLPS-Viv-0152Vitis vinifera45.616e-0954.3
LLPS-Cogr-1224Colletotrichum graminicola45.65e-2392.4
LLPS-Trr-1497Trichoderma reesei45.163e-2290.1
LLPS-Ori-0215Oryza indica44.781e-1059.7
LLPS-Beb-1447Beauveria bassiana44.721e-2394.0
LLPS-Aso-0036Aspergillus oryzae44.533e-2495.5
LLPS-Asf-0112Aspergillus flavus44.533e-2495.5
LLPS-Ved-0586Verticillium dahliae44.01e-2291.3
LLPS-Cog-0820Colletotrichum gloeosporioides41.321e-2291.3
LLPS-Osl-0301Ostreococcus lucimarinus41.188e-2186.7
LLPS-Gas-0079Galdieria sulphuraria40.718e-1673.9
LLPS-Caj-3231Callithrix jacchus38.182e-1469.3
LLPS-Mup-0417Mustela putorius furo37.721e-1573.2
LLPS-Mam-1137Macaca mulatta37.611e-1470.5
LLPS-Sah-0333Sarcophilus harrisii37.384e-1263.2
LLPS-Cea-2241Cercocebus atys37.275e-1571.2
LLPS-Aon-1526Aotus nancymaae37.274e-1468.9
LLPS-Maf-0683Macaca fascicularis37.276e-1571.2
LLPS-Chs-0678Chlorocebus sabaeus37.275e-1571.2
LLPS-Gog-0120Gorilla gorilla37.278e-1570.9
LLPS-Paa-1054Papio anubis37.275e-1571.2
LLPS-Mal-0106Mandrillus leucophaeus37.275e-1571.2
LLPS-Man-0731Macaca nemestrina37.275e-1571.2
LLPS-Hos-0365Homo sapiens37.277e-1570.9
LLPS-Pap-2085Pan paniscus37.277e-1570.9
LLPS-Pat-1640Pan troglodytes37.277e-1570.9
LLPS-Rhb-3053Rhinopithecus bieti37.275e-1571.2
LLPS-Poa-0787Pongo abelii37.274e-1571.2
LLPS-Nol-1232Nomascus leucogenys37.275e-1571.2
LLPS-Sem-0770Selaginella moellendorffii36.946e-1673.6
LLPS-Pes-2741Pelodiscus sinensis36.944e-1571.6
LLPS-Caf-0057Canis familiaris36.73e-1469.3
LLPS-Loa-1207Loxodonta africana36.361e-1264.7
LLPS-Anc-2604Anolis carolinensis36.361e-1265.1
LLPS-Ict-0058Ictidomys tridecemlineatus36.362e-1367.0
LLPS-Mod-2072Monodelphis domestica36.114e-1263.2
LLPS-Blg-0616Blumeria graminis35.92e-1263.5
LLPS-Dio-2395Dipodomys ordii35.851e-1367.8
LLPS-Cas-2272Carlito syrichta35.452e-1264.3
LLPS-Art-2620Arabidopsis thaliana35.43e-0954.7
LLPS-Aim-0131Ailuropoda melanoleuca35.299e-1262.4
LLPS-Icp-1193Ictalurus punctatus35.142e-1675.1
LLPS-Cii-1170Ciona intestinalis35.097e-1159.7
LLPS-Ere-0088Erinaceus europaeus34.861e-1470.5
LLPS-Otg-0434Otolemur garnettii34.556e-1365.9
LLPS-Gaa-0334Gasterosteus aculeatus34.263e-1366.2
LLPS-Brr-2329Brassica rapa34.264e-0851.6
LLPS-Arl-1571Arabidopsis lyrata34.234e-1057.4
LLPS-Mea-2746Mesocricetus auratus34.213e-1366.6
LLPS-Dar-0889Danio rerio34.215e-1365.9
LLPS-Orbr-0679Oryza brachyantha34.193e-1572.0
LLPS-Chr-0124Chlamydomonas reinhardtii34.151e-1675.9
LLPS-Ova-0097Ovis aries33.942e-1367.0
LLPS-Eqc-0439Equus caballus33.945e-1365.9
LLPS-Brd-0507Brachypodium distachyon33.92e-1777.8
LLPS-Brn-2317Brassica napus33.641e-0853.1
LLPS-Mum-0679Mus musculus33.647e-1365.5
LLPS-Lac-0329Latimeria chalumnae33.643e-1263.9
LLPS-Bro-0922Brassica oleracea33.641e-0853.1
LLPS-Ten-1635Tetraodon nigroviridis33.629e-1467.8
LLPS-Cis-1188Ciona savignyi33.333e-1058.2
LLPS-Mua-0072Musa acuminata33.333e-1777.0
LLPS-Asm-3137Astyanax mexicanus33.333e-1572.0
LLPS-Mao-1289Magnaporthe oryzae33.337e-1159.7
LLPS-Bot-1119Bos taurus33.036e-1365.5
LLPS-Orc-0287Oryctolagus cuniculus33.036e-1262.8
LLPS-Cap-1482Cavia porcellus33.031e-1161.6
LLPS-Sus-2681Sus scrofa33.022e-1264.7
LLPS-Fud-0016Fukomys damarensis32.951e-0955.8
LLPS-Map-0014Magnaporthe poae32.763e-1160.5
LLPS-Scf-0896Scleropages formosus32.761e-1162.0
LLPS-Orl-2222Oryzias latipes32.714e-1160.5
LLPS-Tar-0795Takifugu rubripes32.465e-1365.5
LLPS-Xim-2465Xiphophorus maculatus32.435e-1262.8
LLPS-Scm-0485Scophthalmus maximus32.434e-1468.6
LLPS-Cae-1738Caenorhabditis elegans32.381e-0750.4
LLPS-Orb-1029Oryza barthii32.22e-1469.7
LLPS-Orni-0124Oryza nivara32.22e-1469.7
LLPS-Orgl-0333Oryza glumaepatula32.22e-1469.7
LLPS-Orp-0831Oryza punctata32.21e-1470.1
LLPS-Ors-0757Oryza sativa32.26e-1468.6
LLPS-Orr-0397Oryza rufipogon32.26e-1468.6
LLPS-Thc-1753Theobroma cacao32.149e-1365.1
LLPS-Hea-0454Helianthus annuus32.141e-1574.3
LLPS-Fec-2035Felis catus32.112e-1161.6
LLPS-Tut-2432Tursiops truncatus31.582e-0647.0
LLPS-Myl-1677Myotis lucifugus31.582e-1058.9
LLPS-Drm-0910Drosophila melanogaster31.531e-1264.3
LLPS-Mae-0332Manihot esculenta31.362e-1572.4
LLPS-Gor-1929Gossypium raimondii31.253e-1366.2
LLPS-Phv-0347Phaseolus vulgaris30.972e-1777.4
LLPS-Ran-0070Rattus norvegicus30.913e-1263.9
LLPS-Fia-3276Ficedula albicollis30.71e-0750.8
LLPS-Xet-3849Xenopus tropicalis30.76e-0748.5
LLPS-Tra-2572Triticum aestivum30.03e-1469.3
LLPS-Pof-3455Poecilia formosa29.821e-0647.4
LLPS-Orn-0085Oreochromis niloticus29.828e-0748.1
LLPS-Gaga-1358Gallus gallus29.821e-0647.4
LLPS-Org-1417Oryza glaberrima29.662e-1264.7
LLPS-Nec-0992Neurospora crassa29.64e-0645.8
LLPS-Php-0360Physcomitrella patens29.145e-1469.3
LLPS-Leo-3880Lepisosteus oculatus28.954e-0646.2
LLPS-Pot-1060Populus trichocarpa28.953e-1366.2
LLPS-Sot-1322Solanum tuberosum28.76e-0954.3
LLPS-Prp-1592Prunus persica28.73e-1160.8
LLPS-Glm-1676Glycine max28.577e-1159.7
LLPS-Cus-0359Cucumis sativus28.572e-1263.9
LLPS-Nia-0934Nicotiana attenuata28.455e-0954.7
LLPS-Zem-1543Zea mays28.184e-0954.7
LLPS-Orm-0904Oryza meridionalis27.195e-0748.5
LLPS-Dac-0245Daucus carota26.053e-0852.4
LLPS-Sei-0182Setaria italica25.223e-0749.7
LLPS-Sob-0125Sorghum bicolor24.786e-0748.5