• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xim-2766

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: S-adenosylmethionine synthase
Ensembl Gene: ENSXMAG00000019163.2
Ensembl Protein: ENSXMAP00000019204.1
Organism: Xiphophorus maculatus
Taxa ID: 8083
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNPSRGKRSG  KTFLFTSESV  GEGHSDKMCD  QISDAVLDAY  LSQDPDSKVA  CECVAKTGMI  60
61    LLVGEVTSKA  IVDLQSVVRD  TIKKIGYDDS  SKGFDYKTCN  VLVALEPQAE  EISDCVFEGR  120
121   DQEDIGAGDQ  GLMFGYATDE  TEECMPLTLL  LAHKLNHRMR  ELSLNGECPW  ILPDSKSQVT  180
181   VEYRDSEGSL  EPLRVHTVVI  SVQHSPDITL  QEIRHNLMEK  VVKVVVPAKY  LDEKTVYHLL  240
241   PSGKFLMGGP  QGDAGLTGRK  IIVDTYGGWG  GHGGGAFSGK  DYSKVDRSGA  YAARWVAKSL  300
301   VKAGLCKRAL  VQISYAIGVS  HPLSITVFHY  GTSDRDEDEL  LQIVKKNFDL  RPGVIVRELG  360
361   LKRPIYQATA  CYGHFGRKEF  PWEQPKKLVF  390
Nucleotide CDS Sequence (FASTA)
1     ATGAACCCCA  GCAGAGGAAA  GCGCAGTGGG  AAGACTTTTC  TGTTCACGTC  CGAGTCTGTG  60
61    GGGGAAGGAC  ACTCCGATAA  AATGTGCGAT  CAGATCAGCG  ACGCCGTCCT  GGATGCTTAC  120
121   CTGAGTCAGG  ACCCGGACTC  CAAGGTGGCC  TGTGAGTGCG  TGGCAAAGAC  TGGCATGATT  180
181   TTACTGGTTG  GAGAAGTGAC  ATCTAAAGCC  ATCGTGGATC  TCCAGTCCGT  CGTCCGAGAC  240
241   ACCATCAAGA  AGATCGGCTA  TGATGACTCG  TCGAAAGGTT  TCGACTACAA  GACCTGCAAC  300
301   GTGCTGGTGG  CCCTGGAGCC  GCAGGCCGAG  GAGATATCGG  ACTGTGTGTT  TGAAGGAAGA  360
361   GATCAGGAGG  ACATCGGGGC  TGGGGACCAG  GGCCTGATGT  TTGGCTACGC  CACTGACGAG  420
421   ACAGAGGAGT  GTATGCCTCT  AACCCTCCTG  CTGGCTCACA  AACTCAACCA  CAGGATGAGG  480
481   GAGCTTTCGC  TTAACGGAGA  GTGTCCTTGG  ATACTACCAG  ACTCCAAGTC  ACAGGTTACG  540
541   GTGGAGTACC  GAGACAGCGA  GGGCTCCCTG  GAGCCGCTTC  GCGTCCACAC  GGTGGTCATC  600
601   TCCGTGCAGC  ACAGCCCCGA  CATCACCCTG  CAGGAGATCA  GGCACAACCT  GATGGAGAAG  660
661   GTGGTGAAAG  TTGTTGTTCC  TGCCAAGTAT  CTGGACGAGA  AAACCGTCTA  CCACCTGCTG  720
721   CCGAGTGGCA  AGTTTCTAAT  GGGAGGCCCA  CAGGGTGACG  CAGGACTCAC  GGGACGTAAA  780
781   ATCATCGTGG  ACACCTACGG  AGGGTGGGGC  GGCCACGGAG  GTGGAGCTTT  TTCCGGGAAG  840
841   GACTACTCCA  AAGTGGATCG  GTCAGGCGCC  TACGCGGCCC  GTTGGGTCGC  CAAGTCTCTG  900
901   GTCAAAGCGG  GGCTGTGCAA  GAGGGCCCTC  GTTCAGATCT  CGTACGCCAT  CGGCGTGAGT  960
961   CACCCGCTCT  CCATCACCGT  CTTCCACTAC  GGCACGTCGG  ACAGGGACGA  AGACGAGCTG  1020
1021  CTGCAGATAG  TGAAGAAGAA  CTTTGACCTC  CGACCTGGAG  TCATTGTGAG  AGAGCTGGGA  1080
1081  CTAAAGCGGC  CGATTTACCA  GGCCACGGCC  TGCTACGGTC  ACTTTGGAAG  AAAAGAGTTT  1140
1141  CCATGGGAAC  AACCAAAGAA  ACTTGTGTTT  TAA  1173

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
Magnesium
Metal-binding
Nucleotide-binding
One-carbon metabolism
Potassium
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
ATP binding
Molecular Function
Metal ion binding
Molecular Function
Methionine adenosyltransferase activity
Biological Process
One-carbon metabolic process
Biological Process
S-adenosylmethionine biosynthetic process

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pof-1981Poecilia formosa98.720.0 752
LLPS-Tar-0465Takifugu rubripes87.690.0 695
LLPS-Asm-3886Astyanax mexicanus84.910.0 666
LLPS-Icp-3639Ictalurus punctatus84.620.0 673
LLPS-Loa-1113Loxodonta africana75.990.0 579
LLPS-Fec-4399Felis catus75.990.0 579
LLPS-Scf-0619Scleropages formosus75.990.0 578
LLPS-Mup-0096Mustela putorius furo75.990.0 579
LLPS-Dar-0069Danio rerio75.940.0 524
LLPS-Gaa-0123Gasterosteus aculeatus75.930.0 576
LLPS-Sus-4034Sus scrofa75.880.0 559
LLPS-Bot-3022Bos taurus75.880.0 558
LLPS-Otg-1686Otolemur garnettii75.730.0 577
LLPS-Caf-1423Canis familiaris75.730.0 577
LLPS-Ova-3481Ovis aries75.730.0 575
LLPS-Myl-2236Myotis lucifugus75.730.0 578
LLPS-Aim-0592Ailuropoda melanoleuca75.730.0 577
LLPS-Xet-0456Xenopus tropicalis75.720.0 521
LLPS-Leo-3580Lepisosteus oculatus75.660.0 575
LLPS-Eqc-0767Equus caballus75.610.0 558
LLPS-Mod-1707Monodelphis domestica75.460.0 577
LLPS-Pap-1644Pan paniscus75.460.0 576
LLPS-Pat-1352Pan troglodytes75.460.0 576
LLPS-Hos-1410Homo sapiens75.460.0 576
LLPS-Rhb-2929Rhinopithecus bieti75.460.0 577
LLPS-Fia-1380Ficedula albicollis75.460.0 574
LLPS-Mam-2050Macaca mulatta75.460.0 576
LLPS-Poa-1460Pongo abelii75.460.0 576
LLPS-Aon-3122Aotus nancymaae75.460.0 576
LLPS-Cea-1338Cercocebus atys75.460.0 576
LLPS-Chs-3280Chlorocebus sabaeus75.460.0 576
LLPS-Mea-0384Mesocricetus auratus75.460.0 577
LLPS-Mum-3166Mus musculus75.460.0 577
LLPS-Maf-1148Macaca fascicularis75.460.0 576
LLPS-Gog-1123Gorilla gorilla75.460.0 576
LLPS-Dio-1975Dipodomys ordii75.460.0 577
LLPS-Paa-2923Papio anubis75.460.0 576
LLPS-Man-3151Macaca nemestrina75.340.0 557
LLPS-Caj-0295Callithrix jacchus75.340.0 557
LLPS-Anp-2586Anas platyrhynchos75.260.0 583
LLPS-Cap-1493Cavia porcellus75.20.0 572
LLPS-Ict-1511Ictidomys tridecemlineatus75.20.0 574
LLPS-Fud-2583Fukomys damarensis75.20.0 573
LLPS-Ran-3799Rattus norvegicus75.20.0 575
LLPS-Orn-1473Oreochromis niloticus75.130.0 573
LLPS-Ten-3792Tetraodon nigroviridis75.130.0 570
LLPS-Cas-3062Carlito syrichta75.00.0 548
LLPS-Gaga-2483Gallus gallus74.940.0 584
LLPS-Lac-0166Latimeria chalumnae74.670.0 570
LLPS-Meg-3133Meleagris gallopavo74.346e-178 506
LLPS-Orl-1999Oryzias latipes74.340.0 561
LLPS-Pes-2077Pelodiscus sinensis74.222e-164 474
LLPS-Orc-3083Oryctolagus cuniculus74.214e-164 471
LLPS-Nol-0149Nomascus leucogenys74.140.0 573
LLPS-Ora-3195Ornithorhynchus anatinus74.12e-173 494
LLPS-Urm-3561Ursus maritimus74.070.0 569
LLPS-Mal-2151Mandrillus leucophaeus73.880.0 574
LLPS-Tag-1753Taeniopygia guttata73.350.0 558
LLPS-Sah-2557Sarcophilus harrisii73.020.0 565
LLPS-Anc-3057Anolis carolinensis72.890.0 569
LLPS-Cae-0591Caenorhabditis elegans70.740.0 533
LLPS-Scm-1553Scophthalmus maximus70.630.0 516
LLPS-Drm-1266Drosophila melanogaster68.875e-177 506
LLPS-Abg-1295Absidia glauca68.243e-147 429
LLPS-Lem-1484Leptosphaeria maculans66.318e-171 490
LLPS-Yal-1099Yarrowia lipolytica66.058e-175 500
LLPS-Tum-0534Tuber melanosporum65.968e-175 500
LLPS-Usm-0593Ustilago maydis65.873e-173 496
LLPS-Fus-0472Fusarium solani65.792e-174 500
LLPS-Pyt-1142Pyrenophora teres65.71e-167 482
LLPS-Spr-0242Sporisorium reilianum65.611e-171 492
LLPS-Scj-1316Schizosaccharomyces japonicus65.538e-177 505
LLPS-Beb-1295Beauveria bassiana65.262e-166 479
LLPS-Ved-1434Verticillium dahliae65.194e-176 504
LLPS-Kop-0411Komagataella pastoris65.172e-167 481
LLPS-Aso-0972Aspergillus oryzae65.012e-172 494
LLPS-Asf-0281Aspergillus flavus65.012e-172 494
LLPS-Fuo-1211Fusarium oxysporum65.05e-169 486
LLPS-Fuv-0294Fusarium verticillioides65.05e-169 486
LLPS-Gag-0692Gaeumannomyces graminis65.01e-170 490
LLPS-Sac-0497Saccharomyces cerevisiae65.01e-174 499
LLPS-Cog-1285Colletotrichum gloeosporioides64.742e-170 489
LLPS-Map-0958Magnaporthe poae64.742e-166 480
LLPS-Zyt-1323Zymoseptoria tritici64.518e-171 490
LLPS-Miv-1180Microbotryum violaceum64.482e-158 458
LLPS-Nef-1047Neosartorya fischeri64.476e-163 470
LLPS-Asc-1638Aspergillus clavatus64.473e-172 493
LLPS-Trr-1346Trichoderma reesei64.456e-176 503
LLPS-Pytr-1152Pyrenophora triticirepentis64.442e-151 440
LLPS-Asn-1459Aspergillus nidulans64.385e-166 478
LLPS-Asfu-1142Aspergillus fumigatus64.218e-158 457
LLPS-Trv-0078Trichoderma virens64.195e-168 483
LLPS-Coo-1398Colletotrichum orbiculare64.01e-162 473
LLPS-Cogr-1222Colletotrichum graminicola63.921e-171 492
LLPS-Asni-0550Aspergillus niger63.871e-172 494
LLPS-Phn-0147Phaeosphaeria nodorum63.617e-147 429
LLPS-Scp-1449Schizosaccharomyces pombe63.521e-171 492
LLPS-Blg-1155Blumeria graminis63.245e-173 496
LLPS-Dos-1282Dothistroma septosporum62.961e-162 469
LLPS-Mao-1555Magnaporthe oryzae62.928e-171 490
LLPS-Gas-0809Galdieria sulphuraria62.863e-165 476
LLPS-Scc-1206Schizosaccharomyces cryophilus62.371e-168 484
LLPS-Asg-0492Ashbya gossypii62.22e-167 481
LLPS-Gor-1480Gossypium raimondii59.841e-145 426
LLPS-Thc-0757Theobroma cacao59.597e-144 422
LLPS-Prp-1969Prunus persica59.582e-143 420
LLPS-Zem-0594Zea mays59.483e-145 425
LLPS-Brd-0192Brachypodium distachyon59.482e-144 423
LLPS-Brr-2331Brassica rapa59.333e-144 422
LLPS-Coc-0264Corchorus capsularis59.332e-143 421
LLPS-Bro-0473Brassica oleracea59.332e-144 423
LLPS-Brn-3239Brassica napus59.333e-144 422
LLPS-Mae-0443Manihot esculenta59.228e-143 419
LLPS-Hea-0846Helianthus annuus59.223e-143 422
LLPS-Sei-0614Setaria italica59.226e-144 424
LLPS-Viv-1749Vitis vinifera58.963e-141 416
LLPS-Chr-1223Chlamydomonas reinhardtii58.961e-147 431
LLPS-Pot-0114Populus trichocarpa58.914e-143 420
LLPS-Cus-1272Cucumis sativus58.819e-143 419
LLPS-Mua-0437Musa acuminata58.766e-143 419
LLPS-Ors-1298Oryza sativa58.75e-142 417
LLPS-Amt-1643Amborella trichopoda58.72e-141 415
LLPS-Orbr-1919Oryza brachyantha58.73e-142 417
LLPS-Sob-1371Sorghum bicolor58.79e-143 419
LLPS-Orr-0057Oryza rufipogon58.71e-142 418
LLPS-Orm-2003Oryza meridionalis58.71e-142 418
LLPS-Orb-0310Oryza barthii58.71e-142 418
LLPS-Glm-1767Glycine max58.73e-142 417
LLPS-Orni-1417Oryza nivara58.75e-142 417
LLPS-Lep-1398Leersia perrieri58.76e-142 419
LLPS-Orgl-1775Oryza glumaepatula58.71e-142 418
LLPS-Via-1976Vigna angularis58.72e-141 416
LLPS-Tra-1347Triticum aestivum58.616e-144 422
LLPS-Tru-0315Triticum urartu58.554e-142 420
LLPS-Cym-0405Cyanidioschyzon merolae58.491e-149 436
LLPS-Orp-1145Oryza punctata58.449e-142 416
LLPS-Sem-2050Selaginella moellendorffii58.448e-144 421
LLPS-Met-1039Medicago truncatula58.49e-142 416
LLPS-Org-0993Oryza glaberrima58.355e-143 419
LLPS-Dac-2229Daucus carota58.332e-141 416
LLPS-Art-1665Arabidopsis thaliana58.293e-141 415
LLPS-Hov-0917Hordeum vulgare58.297e-141 414
LLPS-Php-1732Physcomitrella patens57.925e-143 420