• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Urm-3139
ARCN1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Coatomer subunit delta
Gene Name: ARCN1
Ensembl Gene: ENSUMAG00000001884.1
Ensembl Protein: ENSUMAP00000002073.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTRTRIEGLL  AAFPKLMNTG  KQHTFVETES  VRYVYQPMEK  LYMVLITTKN  SNILEDLETL  60
61    RLFSRVIPEY  CRALEENEIS  EHCFDLIFAF  DEIVALGYRE  NVNLAQIRTF  TEMDSHEEKV  120
121   FRAVRETQER  EAKAEMRRKA  KELQQARRDA  ERQGKKAPGF  GGFGSSAVSG  GGTAAMITET  180
181   IIETDKPKVA  PAPARPSGPS  KALKLGAKGK  EVDNFVDKLK  SEGETIMSSN  MGKRTSEATK  240
241   VHAPPINMES  VHMKIEEKIT  LTCGRDGGLQ  NMELHGMIML  RISDDKFGRI  RLHVENEDKK  300
301   GVQLQTHPNV  DKKLFTAESL  IGLKNPEKSF  PVNSDVGVLK  WRLQTTEESF  IPLTINCWPS  360
361   ESGHGCDVNI  EYELQEENLE  LSDVIITIPL  PSGVGAPVIG  EIDGEYRHDS  RRNTLEWCLP  420
421   VIDAKNKSGS  LEFSIAGQPN  DFFPVQVSFV  SKRNYCNIQV  TKVTQVDGNS  PVRFSTETTF  480
481   LVDKYEIL  488
Nucleotide CDS Sequence (FASTA)
1     ATGACCCGCA  CTCGAATTGA  GGGCTTGTTA  GCAGCTTTTC  CAAAGCTCAT  GAACACTGGA  60
61    AAACAACATA  CGTTTGTTGA  AACAGAGAGT  GTAAGATATG  TCTACCAGCC  TATGGAGAAG  120
121   CTGTACATGG  TGCTGATCAC  TACCAAAAAC  AGTAACATCT  TAGAAGATCT  GGAGACCCTG  180
181   AGGCTTTTCT  CAAGAGTGAT  CCCTGAGTAT  TGCCGAGCCT  TAGAGGAGAA  TGAGATATCA  240
241   GAGCACTGTT  TTGATTTAAT  TTTTGCTTTT  GATGAAATTG  TTGCCCTGGG  ATACCGGGAG  300
301   AATGTGAACC  TGGCACAAAT  CAGAACCTTC  ACGGAAATGG  ATTCTCATGA  GGAAAAGGTG  360
361   TTCAGAGCAG  TTAGAGAGAC  TCAAGAACGT  GAAGCCAAGG  CTGAGATGCG  GCGTAAAGCA  420
421   AAGGAATTAC  AACAGGCCCG  AAGAGATGCA  GAGAGACAGG  GCAAAAAAGC  CCCAGGATTT  480
481   GGAGGATTTG  GAAGCTCTGC  AGTATCTGGA  GGCGGCACAG  CTGCCATGAT  CACAGAGACC  540
541   ATCATCGAAA  CCGATAAACC  AAAAGTGGCA  CCTGCACCAG  CCAGGCCTTC  AGGCCCCAGC  600
601   AAGGCTTTGA  AACTTGGAGC  CAAAGGGAAG  GAAGTAGATA  ATTTTGTGGA  CAAATTGAAA  660
661   TCTGAAGGTG  AAACTATCAT  GTCCTCAAAT  ATGGGCAAAC  GTACTTCTGA  AGCAACCAAA  720
721   GTGCATGCTC  CACCCATTAA  TATGGAAAGT  GTGCACATGA  AGATTGAGGA  AAAGATCACA  780
781   CTGACTTGTG  GACGGGATGG  AGGATTGCAG  AATATGGAAT  TACATGGCAT  GATCATGCTT  840
841   AGGATCTCAG  ATGATAAATT  TGGCCGAATT  CGTCTTCATG  TGGAAAATGA  AGATAAGAAA  900
901   GGGGTGCAGC  TACAGACCCA  TCCAAATGTG  GATAAAAAAC  TTTTCACTGC  AGAATCTCTC  960
961   ATTGGCCTGA  AGAATCCAGA  GAAGTCATTT  CCAGTGAACA  GTGACGTAGG  GGTGCTAAAG  1020
1021  TGGAGACTCC  AAACCACAGA  AGAGTCTTTT  ATTCCACTGA  CAATTAATTG  CTGGCCCTCA  1080
1081  GAGAGTGGAC  ATGGCTGTGA  TGTGAACATA  GAATACGAGC  TACAAGAGGA  GAATTTAGAA  1140
1141  CTGAGTGATG  TGATTATCAC  CATCCCGCTC  CCATCTGGCG  TGGGTGCACC  GGTGATTGGG  1200
1201  GAGATCGATG  GCGAGTATCG  ACATGACAGC  CGACGAAATA  CCTTGGAGTG  GTGCCTGCCA  1260
1261  GTGATTGATG  CCAAAAATAA  GAGTGGCAGC  CTCGAGTTCA  GCATTGCTGG  GCAGCCCAAC  1320
1321  GACTTCTTCC  CTGTTCAAGT  CTCCTTCGTC  TCCAAAAGAA  ACTACTGTAA  CATACAGATC  1380
1381  AGACAAGGTA  AAGAAATTGA  ATATGAATAC  ATATAA  1416

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Golgi apparatus
Membrane
Protein transport
Reference proteome
Signal
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPI vesicle coat
Cellular Component
Golgi membrane
Biological Process
Protein transport
Biological Process
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-2126Anas platyrhynchos100.02e-84 264
LLPS-Aim-1829Ailuropoda melanoleuca99.390.0 943
LLPS-Caf-0143Canis familiaris98.980.0 944
LLPS-Mup-1132Mustela putorius furo98.980.0 944
LLPS-Fec-2354Felis catus98.570.0 937
LLPS-Caj-0626Callithrix jacchus98.570.0 938
LLPS-Ict-0668Ictidomys tridecemlineatus98.360.0 940
LLPS-Cas-0354Carlito syrichta98.360.0 936
LLPS-Mam-2151Macaca mulatta98.360.0 938
LLPS-Eqc-3845Equus caballus98.360.0 941
LLPS-Mal-2969Mandrillus leucophaeus98.360.0 939
LLPS-Paa-4116Papio anubis98.360.0 939
LLPS-Sus-0832Sus scrofa98.360.0 940
LLPS-Cea-2614Cercocebus atys98.360.0 939
LLPS-Chs-3433Chlorocebus sabaeus98.360.0 940
LLPS-Maf-2388Macaca fascicularis98.360.0 939
LLPS-Mum-4448Mus musculus98.360.0 939
LLPS-Hos-3067Homo sapiens98.160.0 937
LLPS-Pat-3871Pan troglodytes98.160.0 937
LLPS-Ran-0847Rattus norvegicus98.160.0 937
LLPS-Dio-2128Dipodomys ordii98.160.0 938
LLPS-Gog-0258Gorilla gorilla98.160.0 937
LLPS-Aon-1656Aotus nancymaae98.160.0 940
LLPS-Cap-2572Cavia porcellus97.950.0 938
LLPS-Rhb-3429Rhinopithecus bieti97.950.0 939
LLPS-Pap-3178Pan paniscus97.950.0 935
LLPS-Otg-2638Otolemur garnettii97.750.0 935
LLPS-Loa-3314Loxodonta africana97.540.0 930
LLPS-Ova-1870Ovis aries97.540.0 935
LLPS-Bot-2330Bos taurus97.540.0 935
LLPS-Poa-0392Pongo abelii97.40.0 802
LLPS-Fud-3351Fukomys damarensis97.340.0 932
LLPS-Myl-1568Myotis lucifugus97.130.0 932
LLPS-Sah-1829Sarcophilus harrisii97.130.0 927
LLPS-Mod-3759Monodelphis domestica96.930.0 924
LLPS-Mea-0134Mesocricetus auratus96.490.0 798
LLPS-Orc-2833Oryctolagus cuniculus96.360.0 927
LLPS-Tut-1571Tursiops truncatus96.110.0 914
LLPS-Ora-2470Ornithorhynchus anatinus95.290.0 911
LLPS-Pes-2246Pelodiscus sinensis94.880.0 907
LLPS-Gaga-2234Gallus gallus94.260.0 897
LLPS-Meg-2582Meleagris gallopavo94.260.0 895
LLPS-Fia-3274Ficedula albicollis94.060.0 887
LLPS-Man-1552Macaca nemestrina94.060.0 880
LLPS-Anc-0271Anolis carolinensis92.420.0 885
LLPS-Leo-0425Lepisosteus oculatus89.749e-98 306
LLPS-Lac-1528Latimeria chalumnae88.320.0 846
LLPS-Xet-2611Xenopus tropicalis86.530.0 846
LLPS-Scf-1398Scleropages formosus84.630.0 832
LLPS-Nol-3220Nomascus leucogenys84.220.0 766
LLPS-Asm-2282Astyanax mexicanus84.020.0 819
LLPS-Orn-0683Oreochromis niloticus83.810.0 832
LLPS-Tar-1064Takifugu rubripes83.810.0 833
LLPS-Ten-0971Tetraodon nigroviridis83.40.0 824
LLPS-Pof-3343Poecilia formosa82.340.0 814
LLPS-Scm-3153Scophthalmus maximus82.170.0 820
LLPS-Gaa-0001Gasterosteus aculeatus82.170.0 815
LLPS-Xim-1974Xiphophorus maculatus82.140.0 813
LLPS-Orl-1932Oryzias latipes82.140.0 807
LLPS-Icp-0069Ictalurus punctatus81.150.0 814
LLPS-Dar-3045Danio rerio79.30.0 794
LLPS-Vir-0272Vigna radiata76.062e-27 117
LLPS-Cii-0095Ciona intestinalis63.270.0 622
LLPS-Cis-1418Ciona savignyi62.240.0 617
LLPS-Spr-0799Sporisorium reilianum58.825e-56 201
LLPS-Usm-1220Ustilago maydis58.828e-56 201
LLPS-Chc-1143Chondrus crispus56.822e-42 163
LLPS-Drm-1002Drosophila melanogaster55.690.0 527
LLPS-Osl-0285Ostreococcus lucimarinus55.481e-51 186
LLPS-Crn-0447Cryptococcus neoformans51.391e-42 157
LLPS-Cae-0275Caenorhabditis elegans48.413e-149 444
LLPS-Scp-0650Schizosaccharomyces pombe48.379e-44 160
LLPS-Scc-0722Schizosaccharomyces cryophilus47.373e-42 156
LLPS-Kop-0102Komagataella pastoris46.792e-40 158
LLPS-Scj-0823Schizosaccharomyces japonicus44.814e-47 169
LLPS-Sem-1250Selaginella moellendorffii43.096e-141 422
LLPS-Tru-0969Triticum urartu41.862e-126 389
LLPS-Thc-0800Theobroma cacao41.686e-134 405
LLPS-Via-1854Vigna angularis41.333e-138 416
LLPS-Met-0695Medicago truncatula41.252e-134 406
LLPS-Gor-1498Gossypium raimondii41.052e-130 396
LLPS-Phv-1395Phaseolus vulgaris41.024e-138 416
LLPS-Sol-1778Solanum lycopersicum40.942e-129 393
LLPS-Chr-0655Chlamydomonas reinhardtii40.893e-134 405
LLPS-Abg-0017Absidia glauca40.737e-120 382
LLPS-Org-2113Oryza glaberrima40.673e-120 369
LLPS-Sac-0965Saccharomyces cerevisiae40.659e-32 131
LLPS-Mae-2473Manihot esculenta40.592e-130 396
LLPS-Glm-1889Glycine max40.434e-136 410
LLPS-Prp-0561Prunus persica40.393e-133 403
LLPS-Mua-2095Musa acuminata40.282e-129 394
LLPS-Coc-1040Corchorus capsularis40.252e-121 374
LLPS-Hov-2106Hordeum vulgare40.123e-128 389
LLPS-Sob-1708Sorghum bicolor40.085e-127 387
LLPS-Cus-0709Cucumis sativus40.084e-131 397
LLPS-Orm-0590Oryza meridionalis40.03e-124 382
LLPS-Sei-0946Setaria italica40.02e-124 380
LLPS-Php-1277Physcomitrella patens39.967e-132 399
LLPS-Viv-1086Vitis vinifera39.811e-128 392
LLPS-Lep-0520Leersia perrieri39.83e-119 373
LLPS-Zem-0866Zea mays39.762e-124 380
LLPS-Pot-0367Populus trichocarpa39.611e-127 390
LLPS-Tra-2206Triticum aestivum39.61e-124 381
LLPS-Brd-0080Brachypodium distachyon39.69e-123 376
LLPS-Dac-1206Daucus carota39.574e-129 392
LLPS-Orb-0539Oryza barthii39.573e-119 382
LLPS-Amt-1688Amborella trichopoda39.496e-128 389
LLPS-Hea-1232Helianthus annuus39.462e-125 383
LLPS-Ori-0649Oryza indica39.454e-123 380
LLPS-Orni-0353Oryza nivara39.177e-119 380
LLPS-Orbr-1249Oryza brachyantha38.931e-125 384
LLPS-Orr-0766Oryza rufipogon38.894e-119 380
LLPS-Sot-0506Solanum tuberosum38.875e-123 378
LLPS-Orp-1482Oryza punctata38.746e-125 382
LLPS-Ors-0508Oryza sativa38.742e-125 383
LLPS-Nia-2346Nicotiana attenuata38.675e-125 382
LLPS-Scs-0589Sclerotinia sclerotiorum38.632e-108 338
LLPS-Gas-0998Galdieria sulphuraria38.517e-108 338
LLPS-Brr-1865Brassica rapa38.333e-120 369
LLPS-Arl-0230Arabidopsis lyrata37.722e-114 355
LLPS-Orgl-0092Oryza glumaepatula37.624e-115 363
LLPS-Art-0026Arabidopsis thaliana37.521e-116 360
LLPS-Blg-0140Blumeria graminis37.42e-99 315
LLPS-Brn-0526Brassica napus37.161e-116 362
LLPS-Bro-0476Brassica oleracea36.961e-117 363
LLPS-Yal-0294Yarrowia lipolytica36.613e-85 278
LLPS-Asf-0280Aspergillus flavus36.361e-99 316
LLPS-Aso-1283Aspergillus oryzae36.361e-99 316
LLPS-Fus-0150Fusarium solani36.225e-95 304
LLPS-Tum-0939Tuber melanosporum36.22e-85 290
LLPS-Asfu-1462Aspergillus fumigatus36.061e-98 315
LLPS-Nef-0152Neosartorya fischeri36.067e-100 317
LLPS-Fuv-0695Fusarium verticillioides36.045e-97 309
LLPS-Asc-0649Aspergillus clavatus35.832e-101 321
LLPS-Beb-1159Beauveria bassiana35.811e-99 316
LLPS-Nec-1049Neurospora crassa35.818e-94 301
LLPS-Gag-0377Gaeumannomyces graminis35.64e-99 315
LLPS-Asni-1316Aspergillus niger35.481e-97 310
LLPS-Ved-0716Verticillium dahliae35.472e-97 310
LLPS-Map-1251Magnaporthe poae35.41e-98 313
LLPS-Ast-0692Aspergillus terreus35.232e-95 305
LLPS-Pug-1120Puccinia graminis35.191e-97 311
LLPS-Mao-0160Magnaporthe oryzae34.948e-98 311
LLPS-Lem-1295Leptosphaeria maculans34.98e-93 298
LLPS-Trr-0103Trichoderma reesei34.882e-96 307
LLPS-Asn-0229Aspergillus nidulans34.862e-98 313
LLPS-Phn-0440Phaeosphaeria nodorum34.832e-92 298
LLPS-Coo-0293Colletotrichum orbiculare34.717e-95 303
LLPS-Pytr-0689Pyrenophora triticirepentis34.682e-91 295
LLPS-Miv-0586Microbotryum violaceum34.461e-92 299
LLPS-Pyt-0068Pyrenophora teres34.425e-90 291
LLPS-Put-0605Puccinia triticina34.351e-91 296
LLPS-Trv-1373Trichoderma virens34.342e-93 300
LLPS-Cog-1239Colletotrichum gloeosporioides34.272e-92 296
LLPS-Mel-0284Melampsora laricipopulina34.125e-103 326
LLPS-Dos-0054Dothistroma septosporum33.982e-89 289
LLPS-Zyt-0728Zymoseptoria tritici33.973e-90 291
LLPS-Cogr-0652Colletotrichum graminicola33.735e-92 296
LLPS-Fuo-0544Fusarium oxysporum33.23e-81 267
LLPS-Asg-1030Ashbya gossypii32.865e-63 220
LLPS-Cym-0254Cyanidioschyzon merolae32.193e-82 273