• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-0134
Arcn1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Coatomer subunit delta
Gene Name: Arcn1
Ensembl Gene: ENSMAUG00000014545.1
Ensembl Protein: ENSMAUP00000014931.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

▼ SEQUENCE

Protein Sequence (FASTA)
1     IAKIVFEIYI  PEYCRALEEN  EISEHCFDLI  FAFDEIVALG  YRENVNLAQI  RTFTEMDSHE  60
61    EKVFRAVRET  QEREAKAEMR  RKAKELQQAR  RDAERQGKKA  PGFGGFGSSA  VSGGSTAAMI  120
121   TETIIETDKP  KVAPAPSRPS  GPSKALKLGA  KGKEVDNFVD  KLKSEGETIM  SSNMGKRASE  180
181   ATKVHAVPIN  MESVHMKIEE  KITLTCGRDG  GLQNMELHGM  IMLRISDDKF  GRIRLHVENE  240
241   DKKGVQLQTH  PNVDKKLFTA  ESLIGLKNPE  KSFPVNSDVG  VLKWRLQTTE  ESFIPLTINC  300
301   WPSESGNGCD  VNIEYELQED  NLELNDVVIT  IPLPSGVGAP  VIGEIDGEYR  HDSRRNTLEW  360
361   CLPVIDAKNK  SGSLEFSIPG  QPNDFFPVQV  SFISKKNYCN  IQVTKVTQVD  GNSPVRFSTE  420
421   TTFLVDKYEI  L  431
Nucleotide CDS Sequence (FASTA)
1     ATTGCTAAGA  TTGTTTTTGA  AATTTATATT  CCTGAATATT  GCCGCGCCTT  AGAGGAAAAT  60
61    GAAATATCTG  AGCACTGTTT  TGATTTGATT  TTTGCTTTTG  ATGAAATTGT  TGCCCTGGGA  120
121   TACCGGGAGA  ATGTTAACTT  GGCACAGATC  AGAACCTTCA  CAGAAATGGA  TTCTCATGAG  180
181   GAGAAAGTGT  TCAGAGCAGT  CAGAGAGACT  CAAGAACGTG  AAGCTAAGGC  TGAGATGCGG  240
241   CGTAAAGCAA  AGGAATTACA  ACAGGCCCGA  AGAGATGCAG  AGAGACAGGG  CAAAAAAGCA  300
301   CCAGGATTTG  GTGGATTCGG  CAGTTCTGCA  GTGTCTGGAG  GCAGCACAGC  AGCCATGATC  360
361   ACAGAGACTA  TCATTGAAAC  TGATAAACCA  AAAGTGGCAC  CTGCACCATC  CAGACCTTCT  420
421   GGCCCCAGCA  AGGCTTTGAA  ACTTGGAGCC  AAAGGAAAGG  AAGTAGATAA  CTTTGTGGAC  480
481   AAACTGAAAT  CTGAAGGTGA  AACTATTATG  TCTTCTAATA  TGGGGAAACG  TGCCTCAGAA  540
541   GCAACCAAAG  TGCATGCTGT  GCCCATTAAT  ATGGAAAGTG  TGCATATGAA  GATTGAAGAA  600
601   AAGATCACAC  TAACCTGTGG  GAGAGATGGA  GGATTACAGA  ATATGGAGTT  GCATGGCATG  660
661   ATCATGCTTA  GAATCTCAGA  TGACAAATTT  GGCCGGATTC  GTCTTCATGT  AGAAAATGAA  720
721   GATAAGAAAG  GGGTGCAGCT  ACAGACCCAT  CCAAATGTGG  ACAAGAAGCT  TTTCACTGCA  780
781   GAGTCTCTCA  TTGGCTTGAA  AAACCCAGAG  AAGTCATTTC  CAGTCAACAG  TGATGTAGGT  840
841   GTACTAAAGT  GGAGACTACA  GACAACAGAG  GAGTCTTTCA  TTCCCTTGAC  AATTAATTGC  900
901   TGGCCTTCTG  AAAGTGGAAA  TGGTTGTGAT  GTCAACATAG  AATATGAACT  ACAGGAAGAT  960
961   AATTTAGAGC  TCAATGATGT  GGTCATCACC  ATCCCACTCC  CATCGGGTGT  TGGTGCACCA  1020
1021  GTGATTGGTG  AGATTGATGG  GGAATATCGA  CACGACAGTA  GGCGAAATAC  CTTGGAGTGG  1080
1081  TGCCTGCCAG  TGATTGATGC  CAAAAATAAG  AGTGGCAGCC  TGGAGTTCAG  CATTCCTGGG  1140
1141  CAGCCCAATG  ACTTCTTCCC  TGTTCAAGTT  TCCTTCATCT  CCAAAAAAAA  TTACTGCAAC  1200
1201  ATACAGGTTA  CCAAAGTGAC  CCAGGTAGAT  GGAAACAGCC  CCGTCAGGTT  TTCCACAGAG  1260
1261  ACCACTTTCT  TAGTGGACAA  ATATGAAATC  CTGTAA  1296

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Golgi apparatus
Membrane
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPI vesicle coat
Cellular Component
Golgi membrane
Biological Process
Protein transport
Biological Process
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mum-4448Mus musculus98.360.0 803
LLPS-Ran-0847Rattus norvegicus98.130.0 801
LLPS-Ict-0668Ictidomys tridecemlineatus97.890.0 798
LLPS-Cas-0354Carlito syrichta97.890.0 795
LLPS-Poa-0392Pongo abelii97.870.0 790
LLPS-Dio-2128Dipodomys ordii97.660.0 796
LLPS-Mup-1132Mustela putorius furo97.660.0 799
LLPS-Caf-0143Canis familiaris97.660.0 799
LLPS-Otg-2638Otolemur garnettii97.420.0 797
LLPS-Cap-2572Cavia porcellus97.420.0 796
LLPS-Eqc-3845Equus caballus97.420.0 795
LLPS-Nol-3220Nomascus leucogenys97.250.0 669
LLPS-Caj-0626Callithrix jacchus97.190.0 794
LLPS-Gog-0258Gorilla gorilla97.190.0 795
LLPS-Hos-3067Homo sapiens97.190.0 795
LLPS-Pat-3871Pan troglodytes97.190.0 795
LLPS-Fec-2354Felis catus97.190.0 792
LLPS-Sus-0832Sus scrofa96.960.0 796
LLPS-Cea-2614Cercocebus atys96.960.0 795
LLPS-Maf-2388Macaca fascicularis96.960.0 795
LLPS-Chs-3433Chlorocebus sabaeus96.960.0 796
LLPS-Bot-2330Bos taurus96.960.0 796
LLPS-Mal-2969Mandrillus leucophaeus96.960.0 795
LLPS-Paa-4116Papio anubis96.960.0 795
LLPS-Pap-3178Pan paniscus96.960.0 792
LLPS-Rhb-3429Rhinopithecus bieti96.960.0 795
LLPS-Mam-2151Macaca mulatta96.960.0 795
LLPS-Aon-1656Aotus nancymaae96.720.0 796
LLPS-Fud-3351Fukomys damarensis96.720.0 791
LLPS-Aim-1829Ailuropoda melanoleuca96.720.0 794
LLPS-Ova-1870Ovis aries96.490.0 795
LLPS-Myl-1568Myotis lucifugus96.490.0 792
LLPS-Loa-3314Loxodonta africana96.490.0 788
LLPS-Urm-3139Ursus maritimus96.490.0 790
LLPS-Sah-1829Sarcophilus harrisii96.250.0 784
LLPS-Orc-2833Oryctolagus cuniculus95.850.0 788
LLPS-Tut-1571Tursiops truncatus95.320.0 772
LLPS-Mod-3759Monodelphis domestica95.320.0 780
LLPS-Ora-2470Ornithorhynchus anatinus94.150.0 770
LLPS-Anp-2126Anas platyrhynchos93.852e-34 131
LLPS-Meg-2582Meleagris gallopavo93.210.0 755
LLPS-Pes-2246Pelodiscus sinensis93.210.0 767
LLPS-Gaga-2234Gallus gallus93.210.0 757
LLPS-Man-1552Macaca nemestrina92.040.0 737
LLPS-Fia-3274Ficedula albicollis92.040.0 746
LLPS-Anc-0271Anolis carolinensis90.40.0 742
LLPS-Lac-1528Latimeria chalumnae86.890.0 708
LLPS-Leo-0425Lepisosteus oculatus84.334e-49 177
LLPS-Xet-2611Xenopus tropicalis81.820.0 709
LLPS-Scf-1398Scleropages formosus81.030.0 689
LLPS-Tar-1064Takifugu rubripes80.80.0 692
LLPS-Ten-0971Tetraodon nigroviridis80.80.0 687
LLPS-Asm-2282Astyanax mexicanus80.560.0 677
LLPS-Orn-0683Oreochromis niloticus80.560.0 692
LLPS-Gaa-0001Gasterosteus aculeatus79.160.0 678
LLPS-Scm-3153Scophthalmus maximus78.920.0 681
LLPS-Orl-1932Oryzias latipes78.640.0 669
LLPS-Pof-3343Poecilia formosa78.640.0 672
LLPS-Xim-1974Xiphophorus maculatus78.40.0 671
LLPS-Icp-0069Ictalurus punctatus78.220.0 681
LLPS-Dar-2441Danio rerio76.920.0 647
LLPS-Cii-0095Ciona intestinalis58.042e-169 493
LLPS-Cis-1418Ciona savignyi57.443e-167 487
LLPS-Drm-1002Drosophila melanogaster50.06e-135 405
LLPS-Spr-0799Sporisorium reilianum48.911e-21 101
LLPS-Usm-1220Ustilago maydis48.911e-21 101
LLPS-Kop-0102Komagataella pastoris48.811e-1789.4
LLPS-Crn-0447Cryptococcus neoformans48.617e-1578.2
LLPS-Cym-0254Cyanidioschyzon merolae46.751e-1377.0
LLPS-Osl-0285Ostreococcus lucimarinus45.988e-1889.0
LLPS-Cae-0275Caenorhabditis elegans45.182e-112 347
LLPS-Scp-0650Schizosaccharomyces pombe44.835e-1784.3
LLPS-Scc-0722Schizosaccharomyces cryophilus43.91e-1580.1
LLPS-Chc-1143Chondrus crispus43.373e-73 246
LLPS-Orm-0590Oryza meridionalis42.172e-1479.7
LLPS-Vir-0272Vigna radiata39.546e-73 241
LLPS-Scj-0823Schizosaccharomyces japonicus39.131e-1477.0
LLPS-Sem-1250Selaginella moellendorffii38.261e-98 311
LLPS-Php-1277Physcomitrella patens37.442e-95 303
LLPS-Abg-0017Absidia glauca37.211e-86 290
LLPS-Gor-1498Gossypium raimondii37.051e-91 293
LLPS-Via-1854Vigna angularis36.911e-97 309
LLPS-Met-0695Medicago truncatula36.911e-96 306
LLPS-Thc-0800Theobroma cacao36.791e-93 298
LLPS-Phv-1395Phaseolus vulgaris36.697e-97 307
LLPS-Sol-1778Solanum lycopersicum36.656e-90 289
LLPS-Tru-0969Triticum urartu36.612e-87 285
LLPS-Sac-0965Saccharomyces cerevisiae36.566e-1271.6
LLPS-Mae-2473Manihot esculenta36.497e-91 291
LLPS-Dac-1206Daucus carota35.971e-92 296
LLPS-Org-2113Oryza glaberrima35.772e-80 264
LLPS-Glm-1889Glycine max35.651e-94 301
LLPS-Prp-0561Prunus persica35.632e-93 298
LLPS-Coc-1040Corchorus capsularis35.588e-83 271
LLPS-Hov-2106Hordeum vulgare35.532e-89 287
LLPS-Pot-0367Populus trichocarpa35.512e-89 289
LLPS-Cus-0709Cucumis sativus35.496e-93 297
LLPS-Sei-0946Setaria italica35.487e-86 278
LLPS-Scs-0589Sclerotinia sclerotiorum35.474e-72 241
LLPS-Viv-1086Vitis vinifera35.411e-89 289
LLPS-Chr-0655Chlamydomonas reinhardtii35.282e-92 295
LLPS-Mua-2095Musa acuminata35.215e-88 284
LLPS-Zem-0866Zea mays35.073e-86 279
LLPS-Sot-0506Solanum tuberosum34.982e-83 273
LLPS-Orb-0539Oryza barthii34.922e-80 274
LLPS-Sob-1708Sorghum bicolor34.813e-87 282
LLPS-Orbr-1249Oryza brachyantha34.621e-86 280
LLPS-Hea-1232Helianthus annuus34.511e-86 280
LLPS-Mel-0284Melampsora laricipopulina34.484e-77 256
LLPS-Ori-0649Oryza indica34.478e-85 278
LLPS-Orni-0353Oryza nivara34.395e-82 278
LLPS-Gas-0998Galdieria sulphuraria34.352e-74 249
LLPS-Lep-0520Leersia perrieri34.335e-81 270
LLPS-Orr-0766Oryza rufipogon34.325e-81 275
LLPS-Tra-2206Triticum aestivum34.315e-85 276
LLPS-Amt-1688Amborella trichopoda34.318e-89 286
LLPS-Blg-0140Blumeria graminis34.174e-67 229
LLPS-Brd-0080Brachypodium distachyon34.171e-84 275
LLPS-Orp-1482Oryza punctata34.163e-85 277
LLPS-Ors-0508Oryza sativa34.162e-85 277
LLPS-Nia-2346Nicotiana attenuata34.084e-85 276
LLPS-Asni-1316Aspergillus niger33.791e-65 225
LLPS-Nef-0152Neosartorya fischeri33.794e-67 229
LLPS-Asfu-1462Aspergillus fumigatus33.793e-66 228
LLPS-Aso-1283Aspergillus oryzae33.724e-67 229
LLPS-Asf-0280Aspergillus flavus33.724e-67 229
LLPS-Arl-0230Arabidopsis lyrata33.563e-77 256
LLPS-Brr-1865Brassica rapa33.562e-80 264
LLPS-Art-0026Arabidopsis thaliana33.333e-79 261
LLPS-Asc-0649Aspergillus clavatus33.182e-68 233
LLPS-Pug-1120Puccinia graminis33.041e-70 239
LLPS-Beb-1159Beauveria bassiana33.036e-68 231
LLPS-Yal-0294Yarrowia lipolytica32.952e-53 192
LLPS-Ast-0692Aspergillus terreus32.924e-64 221
LLPS-Miv-0586Microbotryum violaceum32.631e-69 236
LLPS-Brn-0526Brassica napus32.593e-79 263
LLPS-Bro-0476Brassica oleracea32.593e-80 264
LLPS-Orgl-0092Oryza glumaepatula32.572e-77 261
LLPS-Asn-0229Aspergillus nidulans32.561e-65 225
LLPS-Put-0605Puccinia triticina32.462e-64 223
LLPS-Fuv-0695Fusarium verticillioides32.432e-64 221
LLPS-Tum-0939Tuber melanosporum32.228e-55 201
LLPS-Nec-1049Neurospora crassa31.843e-61 213
LLPS-Ved-0716Verticillium dahliae31.515e-64 220
LLPS-Lem-1295Leptosphaeria maculans31.257e-62 215
LLPS-Gag-0377Gaeumannomyces graminis31.216e-66 226
LLPS-Map-1251Magnaporthe poae31.213e-65 224
LLPS-Trr-0103Trichoderma reesei31.156e-64 220
LLPS-Phn-0440Phaeosphaeria nodorum31.119e-61 212
LLPS-Mao-0160Magnaporthe oryzae31.057e-65 223
LLPS-Cog-1239Colletotrichum gloeosporioides30.591e-60 211
LLPS-Coo-0293Colletotrichum orbiculare30.492e-62 216
LLPS-Dos-0054Dothistroma septosporum30.441e-56 201
LLPS-Pyt-0068Pyrenophora teres30.296e-59 207
LLPS-Fus-0150Fusarium solani30.162e-59 208
LLPS-Cogr-0652Colletotrichum graminicola30.143e-59 207
LLPS-Fuo-0544Fusarium oxysporum29.412e-48 178
LLPS-Zyt-0728Zymoseptoria tritici29.194e-57 202
LLPS-Trv-1373Trichoderma virens29.136e-61 212
LLPS-Pytr-0689Pyrenophora triticirepentis28.791e-52 189
LLPS-Asg-1030Ashbya gossypii26.03e-37 147