• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Urm-3068
NUP50

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: nuclear pore complex protein Nup50
Gene Name: NUP50
Ensembl Gene: ENSUMAG00000019877.1
Ensembl Protein: ENSUMAP00000027360.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear pore complex, Nucleolus, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSWSRKALFT  SFYFSLRFEN  MAKRIAEKEL  TDRNWDQEDE  AEEVGTFSVA  SEEVLKNRAI  60
61    KKAKRRNVGF  ESDSGGAFKG  FKGLVVPSGG  GGFSGFGNGA  GGKPLEGLSN  GSGVTSAPPF  120
121   SSARAATESK  AAFGSVAANG  PTSLVDKKIL  TPKTNGDSQQ  PSSSGLASSA  ACPRNAYHKQ  180
181   LAALNCSVRD  WIAKHVDTNP  LCDLTPIFKD  YEKYLAGIEQ  QHGSGGSRSS  ESETNKMPLA  240
241   TQSPSLFGST  KLQQDSPFPF  AGNKAEDPSE  KKTDPSVGAA  SASFNFGKKI  DSSVLGSLNS  300
301   GPLTGFSFSS  GNSSLFGKDL  TQNKPVSSPF  PTNTLEAQAE  GGSSECKGGD  EEENDEPPKV  360
361   VVTEVKEEDA  FYSKKCKLFY  KKDNEFKEKG  VGTLHLKPTA  NQKTQLLVRA  DTSLGNILLN  420
421   VLIPPNMPCT  RTGKNNVLIV  CVPNPPVDEK  NATSPVTMLI  RVKTGEDADE  LHTILLEKKD  480
481   G  481
Nucleotide CDS Sequence (FASTA)
1     ATGTCTTGGT  CTAGAAAAGC  ACTTTTTACT  TCTTTTTACT  TCTCACTTAG  GTTTGAAAAT  60
61    ATGGCCAAGA  GAATTGCTGA  GAAGGAATTG  ACAGATAGGA  ATTGGGATCA  AGAAGATGAA  120
121   GCAGAAGAGG  TGGGAACATT  CTCAGTGGCC  AGTGAGGAAG  TCTTGAAGAA  CAGAGCCATA  180
181   AAGAAAGCAA  AGCGTAGAAA  TGTTGGATTT  GAATCTGATA  GTGGAGGGGC  CTTCAAAGGT  240
241   TTTAAAGGTT  TGGTTGTCCC  TTCTGGAGGA  GGAGGGTTTT  CCGGATTTGG  TAACGGTGCT  300
301   GGAGGGAAGC  CTTTGGAAGG  ACTGTCTAAC  GGAAGTGGTG  TAACTAGCGC  CCCTCCCTTC  360
361   TCCAGCGCAA  GGGCAGCCAC  GGAGAGCAAG  GCAGCCTTTG  GATCTGTCGC  TGCAAATGGT  420
421   CCTACCTCCT  TGGTCGATAA  AAAGATTTTA  ACTCCCAAAA  CTAATGGTGA  CAGTCAGCAG  480
481   CCCTCGTCCT  CTGGCCTTGC  CTCCAGTGCA  GCCTGCCCCC  GGAATGCCTA  TCACAAGCAG  540
541   CTGGCTGCCT  TAAACTGTTC  CGTTCGGGAC  TGGATCGCGA  AGCACGTGGA  CACAAACCCG  600
601   CTGTGCGACC  TGACGCCCAT  CTTTAAAGAC  TACGAGAAAT  ACCTCGCGGG  TATTGAACAG  660
661   CAGCACGGGA  GCGGTGGCAG  CAGGAGTTCC  GAAAGTGAAA  CTAACAAAAT  GCCACTTGCC  720
721   ACACAGTCCC  CTTCCCTGTT  CGGGTCAACA  AAACTGCAGC  AAGACTCGCC  ATTTCCGTTT  780
781   GCCGGCAACA  AGGCGGAGGA  CCCCTCTGAG  AAGAAGACGG  ACCCGTCCGT  AGGAGCCGCA  840
841   AGTGCCTCGT  TTAACTTCGG  CAAGAAAATC  GACAGTTCTG  TCTTGGGCTC  ATTAAACTCC  900
901   GGCCCCCTGA  CTGGATTTTC  GTTTTCTTCT  GGAAACTCCA  GTTTATTTGG  CAAAGATCTT  960
961   ACCCAGAATA  AACCAGTGTC  TTCACCATTT  CCCACGAACA  CGCTGGAGGC  GCAGGCGGAA  1020
1021  GGCGGCAGCA  GCGAATGTAA  AGGCGGAGAT  GAAGAAGAGA  ATGACGAGCC  ACCCAAAGTA  1080
1081  GTAGTTACTG  AAGTAAAAGA  GGAAGATGCT  TTTTACTCCA  AAAAGTGTAA  ACTGTTTTAC  1140
1141  AAGAAAGACA  ACGAATTTAA  AGAGAAAGGG  GTGGGCACTT  TGCATTTAAA  ACCTACGGCC  1200
1201  AATCAGAAGA  CACAGCTGTT  AGTGCGGGCA  GACACCAGTT  TAGGCAACAT  ACTGCTGAAT  1260
1261  GTTCTGATCC  CACCCAACAT  GCCGTGTACC  CGAACGGGGA  AGAACAACGT  CCTGATCGTA  1320
1321  TGTGTTCCAA  ATCCGCCCGT  CGATGAGAAG  AATGCCACCA  GCCCGGTCAC  CATGTTGATC  1380
1381  CGGGTGAAAA  CAGGCGAGGA  CGCGGACGAG  TTGCACACAA  TTTTACTGGA  GAAAAAGGAT  1440
1441  GGCTGA  1446

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aim-0767Ailuropoda melanoleuca96.960.0 719
LLPS-Gog-3119Gorilla gorilla94.291e-63 214
LLPS-Caf-2288Canis familiaris93.280.0 684
LLPS-Eqc-0022Equus caballus88.030.0 630
LLPS-Fec-0725Felis catus86.350.0 635
LLPS-Nol-1015Nomascus leucogenys86.182e-71 238
LLPS-Bot-1543Bos taurus84.860.0 617
LLPS-Man-3023Macaca nemestrina84.830.0 609
LLPS-Rhb-0355Rhinopithecus bieti84.620.0 612
LLPS-Paa-0227Papio anubis84.40.0 606
LLPS-Mal-0109Mandrillus leucophaeus84.40.0 608
LLPS-Maf-0386Macaca fascicularis84.40.0 608
LLPS-Mam-2710Macaca mulatta84.40.0 608
LLPS-Hos-0714Homo sapiens84.260.0 602
LLPS-Pap-3258Pan paniscus84.260.0 602
LLPS-Chs-1266Chlorocebus sabaeus84.190.0 621
LLPS-Pat-4197Pan troglodytes84.040.0 602
LLPS-Sus-2928Sus scrofa83.970.0 614
LLPS-Cea-3395Cercocebus atys83.970.0 604
LLPS-Poa-0750Pongo abelii83.80.0 596
LLPS-Caj-0833Callithrix jacchus83.330.0 601
LLPS-Ova-2994Ovis aries82.690.0 581
LLPS-Mup-1332Mustela putorius furo82.63e-180 521
LLPS-Cas-0521Carlito syrichta81.450.0 609
LLPS-Aon-2116Aotus nancymaae81.410.0 595
LLPS-Otg-3939Otolemur garnettii81.280.0 562
LLPS-Myl-1336Myotis lucifugus79.490.0 545
LLPS-Loa-0030Loxodonta africana79.130.0 594
LLPS-Fud-1259Fukomys damarensis79.060.0 583
LLPS-Ran-0540Rattus norvegicus78.80.0 541
LLPS-Ere-0376Erinaceus europaeus77.830.0 553
LLPS-Mum-0590Mus musculus76.50.0 528
LLPS-Orc-0026Oryctolagus cuniculus76.330.0 533
LLPS-Ict-0932Ictidomys tridecemlineatus74.735e-154 453
LLPS-Dio-0164Dipodomys ordii74.153e-164 480
LLPS-Mea-1819Mesocricetus auratus70.627e-133 397
LLPS-Meg-1995Meleagris gallopavo70.048e-156 458
LLPS-Anp-2689Anas platyrhynchos69.891e-151 447
LLPS-Fia-1775Ficedula albicollis69.775e-153 451
LLPS-Pes-0901Pelodiscus sinensis69.72e-161 473
LLPS-Gaga-3117Gallus gallus69.565e-155 456
LLPS-Tag-0661Taeniopygia guttata68.589e-153 450
LLPS-Mod-1881Monodelphis domestica67.013e-162 476
LLPS-Cap-1688Cavia porcellus66.63e-169 493
LLPS-Sah-1382Sarcophilus harrisii63.621e-130 392
LLPS-Ora-0775Ornithorhynchus anatinus62.631e-148 440
LLPS-Anc-2542Anolis carolinensis62.534e-121 371
LLPS-Cis-1105Ciona savignyi61.612e-28 120
LLPS-Cii-0484Ciona intestinalis59.824e-29 122
LLPS-Drm-1884Drosophila melanogaster58.651e-30 129
LLPS-Lac-3413Latimeria chalumnae55.373e-109 339
LLPS-Leo-1208Lepisosteus oculatus54.853e-95 303
LLPS-Scf-2765Scleropages formosus53.071e-104 327
LLPS-Orn-2584Oreochromis niloticus51.261e-101 319
LLPS-Dar-0085Danio rerio50.432e-101 317
LLPS-Icp-0197Ictalurus punctatus50.211e-101 319
LLPS-Orl-2044Oryzias latipes50.111e-97 308
LLPS-Scm-0894Scophthalmus maximus49.682e-78 258
LLPS-Pof-2216Poecilia formosa49.367e-99 311
LLPS-Asm-0398Astyanax mexicanus48.196e-98 311
LLPS-Xim-1373Xiphophorus maculatus47.882e-96 305
LLPS-Ten-1252Tetraodon nigroviridis46.913e-89 285
LLPS-Tar-1609Takifugu rubripes46.789e-88 282
LLPS-Gaa-1341Gasterosteus aculeatus43.782e-80 263
LLPS-Nia-1901Nicotiana attenuata33.042e-0757.0