• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mod-1881
NUP50

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: NUP50
Ensembl Gene: ENSMODG00000007116.3
Ensembl Protein: ENSMODP00000008830.3
Organism: Monodelphis domestica
Taxa ID: 13616
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear pore complex, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKFKLNLKYT  RYKKMAKRNA  EKELTDRNWD  QEDEVEEVGM  FSVASEEVLK  NRAIKKAKRR  60
61    NVAFESESGG  AFKGFKGLVV  PPGGPGGGGG  LAGFGNGTSI  KSLEGLSNGS  GLSCAPTLAT  120
121   AKAPSETKVT  FGRITANGPA  APLVGDKKTS  NPKSNGDSQQ  PSSSGHSVQA  KGGCSASAYH  180
181   KQLAALNCSV  RDWIVKHVDT  NPLCDLTPIF  KDYERYLTSI  EQLPGSSSSN  DGNLEKEASR  240
241   QSPGTQAGPP  PQDTPFLFHP  DKAEGVVEKR  VDVPSEKKPT  PALGVASTAS  FHFGRKVDSS  300
301   VLGSLSTAPM  ANFSFSSGNV  GVFGTDVTQA  KPVSSFSPKV  LESHPDGSAG  EYKGGEEEES  360
361   EEPPKAIVTE  VKEEDAFYSK  KCKLFYKKDN  EFKEKGVGTL  HLKPAGNQKT  QLLVRADTNL  420
421   GNILLNVLVP  PNMPCSRTGK  NNVLIVCVPN  PPISEKHAAI  PVTMLIRVKT  TEDADELHKI  480
481   LLEKKEA  487
Nucleotide CDS Sequence (FASTA)
1     ATGAAATTTA  AACTGAACTT  AAAATATACC  AGGTACAAAA  AAATGGCCAA  AAGGAACGCA  60
61    GAGAAGGAGC  TGACAGACCG  GAATTGGGAC  CAGGAAGATG  AGGTGGAGGA  GGTGGGCATG  120
121   TTCTCAGTGG  CCAGTGAAGA  AGTCTTGAAG  AACAGAGCTA  TCAAGAAGGC  AAAGCGTAGG  180
181   AATGTGGCCT  TCGAATCTGA  AAGTGGAGGG  GCTTTTAAAG  GATTCAAAGG  CTTGGTTGTA  240
241   CCTCCGGGAG  GACCAGGAGG  AGGAGGAGGA  CTTGCTGGCT  TTGGCAATGG  CACCAGCATC  300
301   AAATCTCTGG  AAGGCCTGTC  CAATGGCAGT  GGCCTGTCTT  GTGCACCTAC  CCTAGCCACT  360
361   GCCAAGGCCC  CATCAGAAAC  AAAGGTGACC  TTTGGCCGCA  TCACAGCAAA  TGGCCCTGCG  420
421   GCTCCCTTAG  TTGGGGACAA  GAAGACTTCC  AACCCCAAGA  GCAATGGGGA  CAGCCAGCAG  480
481   CCCTCGTCCT  CTGGCCACAG  TGTACAGGCC  AAGGGTGGCT  GCAGCGCCAG  TGCCTATCAC  540
541   AAACAGCTCG  CTGCCTTAAA  TTGCTCCGTG  CGGGACTGGA  TCGTGAAGCA  CGTGGACACC  600
601   AACCCGCTCT  GTGACCTGAC  ACCCATCTTT  AAAGACTATG  AGCGCTACCT  GACGAGCATC  660
661   GAGCAGCTGC  CTGGCAGCAG  CAGCAGTAAT  GATGGCAACC  TGGAGAAAGA  AGCCAGCAGG  720
721   CAGTCCCCAG  GCACCCAAGC  TGGGCCACCA  CCCCAAGATA  CCCCCTTTTT  GTTTCATCCA  780
781   GACAAAGCTG  AGGGGGTGGT  TGAAAAGAGG  GTTGATGTGC  CATCAGAGAA  GAAACCGACC  840
841   CCGGCCTTAG  GAGTAGCATC  CACTGCCTCC  TTCCACTTTG  GCCGCAAAGT  CGATAGCTCT  900
901   GTTCTGGGTT  CCTTGAGCAC  TGCCCCGATG  GCGAATTTCT  CTTTCTCTTC  TGGAAACGTG  960
961   GGTGTGTTTG  GCACAGACGT  GACCCAGGCA  AAACCTGTCT  CTTCCTTCTC  CCCCAAAGTG  1020
1021  CTGGAGAGCC  ATCCAGATGG  GTCTGCTGGA  GAGTACAAAG  GTGGAGAAGA  AGAAGAGAGT  1080
1081  GAGGAGCCAC  CCAAAGCAAT  TGTGACTGAA  GTCAAAGAAG  AGGATGCCTT  TTATTCAAAG  1140
1141  AAGTGCAAAC  TCTTTTACAA  AAAAGATAAT  GAGTTTAAAG  AGAAGGGTGT  GGGCACGCTG  1200
1201  CACTTGAAAC  CGGCTGGCAA  TCAGAAGACC  CAGCTTCTGG  TTCGAGCTGA  CACTAATTTA  1260
1261  GGGAACATAC  TCCTGAATGT  CCTGGTTCCT  CCCAACATGC  CCTGCTCCCG  AACTGGCAAG  1320
1321  AACAACGTGC  TCATTGTCTG  TGTTCCCAAC  CCGCCCATCA  GCGAGAAGCA  CGCTGCCATC  1380
1381  CCCGTGACAA  TGCTCATCAG  GGTCAAGACC  ACAGAGGACG  CCGACGAGCT  GCACAAAATC  1440
1441  CTCCTAGAGA  AGAAGGAGGC  GTGA  1464

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nol-1015Nomascus leucogenys90.082e-70 235
LLPS-Gog-3119Gorilla gorilla89.627e-62 209
LLPS-Pof-2216Poecilia formosa81.136e-0962.0
LLPS-Lac-3413Latimeria chalumnae79.341e-58 207
LLPS-Leo-1208Lepisosteus oculatus79.318e-1168.2
LLPS-Xim-1373Xiphophorus maculatus77.367e-0858.9
LLPS-Asm-0398Astyanax mexicanus75.633e-55 199
LLPS-Sah-1382Sarcophilus harrisii75.126e-179 516
LLPS-Ten-1252Tetraodon nigroviridis74.146e-1168.2
LLPS-Scm-0894Scophthalmus maximus74.143e-1066.2
LLPS-Orl-2044Oryzias latipes72.417e-1065.1
LLPS-Poa-0750Pongo abelii69.793e-175 508
LLPS-Man-3023Macaca nemestrina69.795e-177 513
LLPS-Rhb-0355Rhinopithecus bieti69.588e-177 512
LLPS-Maf-0386Macaca fascicularis69.586e-176 510
LLPS-Mam-2710Macaca mulatta69.382e-175 508
LLPS-Mal-0109Mandrillus leucophaeus69.381e-175 509
LLPS-Paa-0227Papio anubis69.387e-176 510
LLPS-Chs-1266Chlorocebus sabaeus69.170.0 523
LLPS-Pap-3258Pan paniscus68.961e-175 509
LLPS-Cea-3395Cercocebus atys68.966e-174 505
LLPS-Cas-0521Carlito syrichta68.843e-179 518
LLPS-Eqc-0022Equus caballus68.751e-166 486
LLPS-Pat-4197Pan troglodytes68.751e-175 509
LLPS-Aon-2116Aotus nancymaae68.541e-171 499
LLPS-Aim-0767Ailuropoda melanoleuca68.414e-162 474
LLPS-Hos-0714Homo sapiens68.333e-174 506
LLPS-Urm-3068Ursus maritimus68.055e-160 470
LLPS-Fec-0725Felis catus67.983e-169 493
LLPS-Caj-0833Callithrix jacchus67.51e-170 497
LLPS-Caf-2288Canis familiaris67.295e-161 472
LLPS-Sus-2928Sus scrofa67.095e-172 500
LLPS-Fud-1259Fukomys damarensis66.86e-170 494
LLPS-Otg-3939Otolemur garnettii66.531e-167 489
LLPS-Loa-0030Loxodonta africana65.151e-163 478
LLPS-Bot-1543Bos taurus65.074e-165 483
LLPS-Dio-0164Dipodomys ordii64.85e-144 428
LLPS-Ere-0376Erinaceus europaeus63.962e-152 450
LLPS-Orc-0026Oryctolagus cuniculus63.91e-158 466
LLPS-Mum-0590Mus musculus63.814e-146 434
LLPS-Myl-1336Myotis lucifugus63.752e-160 470
LLPS-Ran-0540Rattus norvegicus63.697e-153 451
LLPS-Fia-1775Ficedula albicollis63.546e-162 474
LLPS-Meg-1995Meleagris gallopavo63.544e-154 454
LLPS-Ova-2994Ovis aries63.281e-160 471
LLPS-Gaga-3117Gallus gallus63.264e-154 454
LLPS-Ora-0775Ornithorhynchus anatinus62.685e-153 452
LLPS-Pes-0901Pelodiscus sinensis62.635e-152 449
LLPS-Tag-0661Taeniopygia guttata62.291e-156 461
LLPS-Anp-2689Anas platyrhynchos61.331e-160 471
LLPS-Cap-1688Cavia porcellus60.463e-153 452
LLPS-Mup-1332Mustela putorius furo59.825e-101 318
LLPS-Anc-2542Anolis carolinensis58.871e-127 388
LLPS-Ict-0932Ictidomys tridecemlineatus58.466e-124 376
LLPS-Mea-1819Mesocricetus auratus58.22e-112 345
LLPS-Drm-1884Drosophila melanogaster53.912e-31 130
LLPS-Scf-2765Scleropages formosus50.21e-97 309
LLPS-Icp-0197Ictalurus punctatus49.499e-102 320
LLPS-Dar-0085Danio rerio48.741e-98 310
LLPS-Orn-2584Oreochromis niloticus47.033e-99 313
LLPS-Gaa-1341Gasterosteus aculeatus46.884e-84 273
LLPS-Cii-0484Ciona intestinalis41.282e-45 170
LLPS-Tar-1609Takifugu rubripes41.273e-88 283
LLPS-Cis-1105Ciona savignyi35.254e-44 167