• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Trv-1088
TRIVIDRAFT_61504

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ribonucleoside-diphosphate reductase
Gene Name: TRIVIDRAFT_61504
Ensembl Gene: TRIVIDRAFT_61504
Ensembl Protein: EHK24730
Organism: Trichoderma virens
Taxa ID: 413071
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEHK24730EHK24730
UniProtG9MKI2, G9MKI2_HYPVG
GeneBankABDF02000004EHK24730.1
RefSeqXM_014103457.1XP_013958932.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MYVRKRDGRQ  ERVQFDKITA  RVSRLCYGLD  TDHVDPVAIT  QKVISGVYGG  VTTVQLDDLA  60
61    AETAAYMTVT  HPDYAILAAR  IAVSNLHKQT  KKQWSAVVSD  LYHYVNPKNS  RASPMISKDT  120
121   YECVMRHKEE  LDSAIVYDRD  FNYQYFGFKT  LERSYLLKLD  GKIVERPQHM  IMRVAVGIWG  180
181   DDIERVLETY  HLMSSKFFTH  ASPTLFNAGT  PQAQLSSCFL  VDMKDDSIEG  IYDTLKTCAM  240
241   ISKMAGGIGL  NVHRIRATGS  YIAGTNGTSN  GIIPMLRVFN  NTARYVDQGG  NKRPGAFAIY  300
301   LEPWHADVFE  FLDLRKNHGK  EEVRARDLFL  ALWIPDLFMK  RVEKNLDWTL  MCPNECPGLA  360
361   DCYGEEFEAL  YEKYEKEGRG  RKTIRAQKLW  YSILEAQTET  GNPFMLYKDH  CNRKSNQKNL  420
421   GTIRSSNLCT  EIIEYCAPDE  VAVCNLASLA  LPAYVDYNEG  CYDFKKLHEV  TKVVVRNLNK  480
481   IIDVNHYPVQ  EARNSNMRHR  PIGVGVQGLA  DAFLALRMPF  ESPEARELNK  QIFETIYHAA  540
541   LEASMEIAKV  EGPYQSFKGS  PASEGILQFD  MWDVKPSDLW  EWDSLKEQIK  EHGVRNSLLV  600
601   APMPTASTSQ  ILGNNECFEP  YTSNIYQRRV  LAGEFQVVNP  WLLKDLVDTG  LWSDAMKNRI  660
661   IAENGSIQNI  PNIPEDIKAL  YKTVWEISQR  QIVQMAADRG  AFIDQSQSLN  IHMKDPTMGK  720
721   ITSMHFTGWK  LGLKTGMYYL  RTQAAAAPIQ  FTVDQEALKV  ADTAVSKDRV  LKKRAPPPGS  780
781   SYMMSSPSAV  PRPSSAKREG  DSGNSLSSNG  VPTPTTTPPP  AVSRPLASPH  KAPPMKADVD  840
841   EGDSPKVLPT  EPSDNVKEEE  LSKKPNQTED  KDEDSEERER  DIYSDAVLAC  SIENPEACVM  900
901   CSG  903
Nucleotide CDS Sequence (FASTA)
1     ATGTATGTGA  GGAAGCGTGA  CGGTCGTCAG  GAGCGTGTTC  AGTTCGACAA  GATCACGGCT  60
61    CGTGTCTCTC  GGCTGTGTTA  CGGCCTGGAC  ACTGACCATG  TCGACCCCGT  AGCCATTACC  120
121   CAGAAGGTCA  TTTCTGGTGT  CTATGGAGGT  GTCACAACAG  TGCAGCTTGA  CGATCTTGCT  180
181   GCCGAGACTG  CCGCCTACAT  GACTGTTACC  CACCCCGACT  ATGCCATCCT  CGCCGCCCGC  240
241   ATCGCCGTCT  CCAACCTCCA  CAAACAAACC  AAGAAGCAGT  GGTCAGCTGT  TGTCAGTGAT  300
301   CTATACCACT  ATGTAAACCC  AAAGAACAGC  AGGGCCTCAC  CCATGATCTC  TAAAGACACA  360
361   TATGAGTGCG  TCATGCGGCA  TAAAGAGGAG  CTCGACTCTG  CCATAGTGTA  TGATCGAGAC  420
421   TTCAACTACC  AATACTTCGG  CTTCAAGACT  CTGGAGCGGT  CATACCTCCT  GAAGCTTGAT  480
481   GGCAAGATTG  TTGAGCGACC  ACAGCACATG  ATTATGCGAG  TGGCTGTTGG  CATCTGGGGA  540
541   GACGACATTG  AGCGTGTCCT  GGAGACATAC  CACCTCATGT  CGAGCAAGTT  CTTCACCCAT  600
601   GCCTCCCCCA  CCCTCTTCAA  CGCTGGTACC  CCGCAGGCCC  AGCTGTCTTC  ATGCTTCTTG  660
661   GTTGACATGA  AGGACGATAG  CATTGAGGGT  ATCTATGACA  CTCTGAAGAC  GTGTGCCATG  720
721   ATTTCCAAGA  TGGCTGGTGG  CATCGGCTTG  AACGTCCACC  GCATCCGTGC  CACCGGCTCT  780
781   TACATTGCAG  GCACCAACGG  TACTTCCAAC  GGTATCATTC  CCATGCTTCG  AGTCTTCAAC  840
841   AACACTGCCA  GATACGTCGA  CCAGGGTGGC  AACAAGCGTC  CTGGTGCCTT  TGCCATCTAC  900
901   CTGGAGCCAT  GGCACGCTGA  TGTCTTTGAG  TTCCTTGATC  TCCGCAAGAA  CCACGGTAAG  960
961   GAGGAGGTCC  GTGCTCGCGA  CTTGTTCCTT  GCTCTCTGGA  TTCCCGATCT  CTTCATGAAG  1020
1021  CGTGTTGAGA  AGAACTTGGA  CTGGACGCTC  ATGTGCCCCA  ACGAGTGCCC  TGGCCTTGCT  1080
1081  GACTGCTATG  GCGAGGAGTT  CGAGGCTTTG  TATGAGAAGT  ACGAGAAGGA  GGGACGTGGT  1140
1141  CGCAAGACTA  TCCGCGCTCA  GAAGCTGTGG  TATTCCATCC  TGGAAGCCCA  GACCGAGACT  1200
1201  GGCAACCCCT  TCATGCTCTA  CAAGGACCAC  TGCAACCGCA  AGAGCAACCA  GAAGAACCTG  1260
1261  GGTACCATCC  GCAGCTCTAA  CCTCTGCACT  GAGATTATTG  AGTACTGTGC  CCCTGATGAG  1320
1321  GTTGCTGTCT  GCAACTTGGC  CTCTTTGGCC  CTCCCTGCCT  ATGTCGACTA  CAACGAAGGG  1380
1381  TGCTATGACT  TTAAGAAGCT  TCACGAAGTC  ACCAAGGTGG  TTGTCCGTAA  CCTGAACAAG  1440
1441  ATTATTGATG  TGAACCACTA  CCCTGTCCAG  GAGGCCCGTA  ACAGCAACAT  GCGTCACAGA  1500
1501  CCTATCGGTG  TTGGTGTCCA  GGGTCTTGCT  GATGCTTTCC  TTGCCCTGCG  CATGCCTTTT  1560
1561  GAGTCTCCTG  AGGCTCGCGA  GCTGAACAAG  CAGATCTTTG  AGACAATCTA  CCACGCTGCC  1620
1621  CTTGAGGCTT  CTATGGAGAT  TGCCAAGGTC  GAGGGCCCCT  ATCAATCATT  CAAGGGATCA  1680
1681  CCTGCATCTG  AGGGCATCCT  TCAATTCGAC  ATGTGGGATG  TCAAGCCCTC  CGACCTGTGG  1740
1741  GAGTGGGACT  CTCTCAAGGA  ACAGATCAAG  GAGCACGGTG  TGCGCAACAG  CTTGCTCGTC  1800
1801  GCCCCTATGC  CAACTGCCAG  CACTTCCCAG  ATCCTGGGCA  ACAATGAGTG  CTTCGAGCCC  1860
1861  TACACCTCCA  ACATCTACCA  GCGCCGTGTC  CTTGCCGGCG  AGTTCCAGGT  TGTCAACCCT  1920
1921  TGGCTTCTCA  AGGACCTGGT  CGACACTGGC  CTCTGGTCCG  ATGCCATGAA  GAACCGTATC  1980
1981  ATTGCTGAGA  ACGGCTCCAT  TCAGAACATC  CCCAACATCC  CCGAGGATAT  CAAGGCCTTG  2040
2041  TACAAGACCG  TCTGGGAGAT  TTCTCAGCGC  CAAATTGTCC  AGATGGCGGC  CGACCGTGGT  2100
2101  GCTTTCATTG  ACCAGTCCCA  GTCCCTGAAC  ATCCACATGA  AGGACCCCAC  AATGGGCAAG  2160
2161  ATTACCAGCA  TGCACTTCAC  TGGCTGGAAG  CTTGGTCTCA  AGACCGGCAT  GTACTACCTT  2220
2221  CGTACCCAGG  CCGCAGCTGC  GCCCATCCAG  TTCACCGTTG  ATCAGGAAGC  CCTCAAGGTT  2280
2281  GCTGATACCG  CCGTCAGCAA  GGACCGTGTC  CTGAAGAAGC  GAGCTCCTCC  CCCAGGATCT  2340
2341  TCCTACATGA  TGTCCTCCCC  CTCCGCCGTC  CCCCGCCCTA  GCAGTGCGAA  GAGGGAAGGA  2400
2401  GACTCTGGCA  ACTCGTTGAG  CTCCAACGGT  GTTCCTACCC  CCACCACCAC  ACCTCCCCCC  2460
2461  GCCGTGAGCA  GGCCTCTGGC  ATCTCCTCAC  AAAGCCCCTC  CTATGAAGGC  CGACGTTGAT  2520
2521  GAGGGAGACA  GCCCCAAGGT  TCTTCCCACT  GAGCCCTCCG  ACAATGTCAA  GGAAGAGGAG  2580
2581  CTGAGCAAGA  AGCCTAACCA  AACCGAAGAC  AAGGACGAGG  ATAGCGAGGA  GCGGGAAAGG  2640
2641  GACATTTACT  CGGACGCTGT  TCTAGCCTGC  AGCATTGAAA  ACCCCGAGGC  TTGCGTTATG  2700
2701  TGCAGTGGCT  AA  2712

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
DNA replication
Nucleotide-binding
Oxidoreductase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
ATP binding
Molecular Function
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Biological Process
DNA replication

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Trr-0172Trichoderma reesei97.010.01726
LLPS-Fuo-1268Fusarium oxysporum94.170.01042
LLPS-Beb-0628Beauveria bassiana87.530.01617
LLPS-Ved-1342Verticillium dahliae86.550.01587
LLPS-Fuv-1027Fusarium verticillioides86.060.01601
LLPS-Fus-0220Fusarium solani85.710.01587
LLPS-Cogr-1211Colletotrichum graminicola85.460.01570
LLPS-Mao-1183Magnaporthe oryzae85.380.01575
LLPS-Cog-0042Colletotrichum gloeosporioides84.580.01561
LLPS-Coo-0064Colletotrichum orbiculare83.570.01559
LLPS-Aso-0344Aspergillus oryzae83.440.01381
LLPS-Asf-0219Aspergillus flavus83.440.01383
LLPS-Asn-0959Aspergillus nidulans83.330.01372
LLPS-Pytr-0520Pyrenophora triticirepentis82.550.01368
LLPS-Gag-0489Gaeumannomyces graminis81.410.01521
LLPS-Map-0472Magnaporthe poae81.30.01521
LLPS-Zyt-0984Zymoseptoria tritici81.140.01333
LLPS-Nec-0887Neurospora crassa77.930.01446
LLPS-Phn-0557Phaeosphaeria nodorum77.150.01413
LLPS-Mel-0824Melampsora laricipopulina76.030.01248
LLPS-Scp-0347Schizosaccharomyces pombe75.890.01235
LLPS-Lem-0078Leptosphaeria maculans75.80.01412
LLPS-Pyt-0593Pyrenophora teres75.770.01405
LLPS-Yal-0520Yarrowia lipolytica75.350.01278
LLPS-Nef-0761Neosartorya fischeri75.30.01390
LLPS-Scj-0125Schizosaccharomyces japonicus75.230.01211
LLPS-Asg-0184Ashbya gossypii75.230.01266
LLPS-Asfu-0249Aspergillus fumigatus75.190.01389
LLPS-Abg-0007Absidia glauca75.10.01233
LLPS-Spr-0372Sporisorium reilianum75.10.01258
LLPS-Scc-0602Schizosaccharomyces cryophilus75.00.01233
LLPS-Rhb-3940Rhinopithecus bieti75.00.0 868
LLPS-Ast-0605Aspergillus terreus74.720.01378
LLPS-Asc-0241Aspergillus clavatus74.670.01393
LLPS-Usm-1209Ustilago maydis74.350.01245
LLPS-Mup-0397Mustela putorius furo74.170.0 782
LLPS-Dos-0469Dothistroma septosporum74.130.01386
LLPS-Tum-1231Tuber melanosporum74.030.01366
LLPS-Tag-1934Taeniopygia guttata73.670.0 629
LLPS-Blg-0395Blumeria graminis73.370.01393
LLPS-Fia-3000Ficedula albicollis73.350.01181
LLPS-Asni-1076Aspergillus niger73.340.01375
LLPS-Ran-2689Rattus norvegicus73.220.01181
LLPS-Ict-1734Ictidomys tridecemlineatus73.220.01181
LLPS-Aim-1490Ailuropoda melanoleuca73.180.0 743
LLPS-Caf-1790Canis familiaris73.090.01177
LLPS-Fec-2350Felis catus73.090.01178
LLPS-Tut-1312Tursiops truncatus72.960.01174
LLPS-Bot-3557Bos taurus72.960.01176
LLPS-Ova-0748Ovis aries72.960.01177
LLPS-Mum-3781Mus musculus72.960.01176
LLPS-Mam-1882Macaca mulatta72.870.01166
LLPS-Myl-2322Myotis lucifugus72.820.01176
LLPS-Sac-1126Saccharomyces cerevisiae72.820.01226
LLPS-Paa-2849Papio anubis72.820.01174
LLPS-Mal-0197Mandrillus leucophaeus72.820.01174
LLPS-Chs-0056Chlorocebus sabaeus72.820.01174
LLPS-Maf-0219Macaca fascicularis72.820.01174
LLPS-Cea-0640Cercocebus atys72.820.01174
LLPS-Cas-3251Carlito syrichta72.820.01172
LLPS-Loa-1547Loxodonta africana72.820.01173
LLPS-Man-0975Macaca nemestrina72.820.01174
LLPS-Ora-2690Ornithorhynchus anatinus72.810.01170
LLPS-Cap-1701Cavia porcellus72.720.01169
LLPS-Gog-0394Gorilla gorilla72.690.01172
LLPS-Poa-1028Pongo abelii72.690.01172
LLPS-Nol-1189Nomascus leucogenys72.690.01171
LLPS-Pat-4006Pan troglodytes72.690.01172
LLPS-Pap-0215Pan paniscus72.690.01172
LLPS-Hos-0396Homo sapiens72.690.01172
LLPS-Eqc-2018Equus caballus72.640.01112
LLPS-Sah-1131Sarcophilus harrisii72.610.01183
LLPS-Dio-1786Dipodomys ordii72.60.01174
LLPS-Orc-1961Oryctolagus cuniculus72.560.01170
LLPS-Fud-0039Fukomys damarensis72.350.01165
LLPS-Otg-0341Otolemur garnettii72.340.01161
LLPS-Gaga-1111Gallus gallus72.30.01185
LLPS-Mea-0066Mesocricetus auratus72.270.01177
LLPS-Cii-0533Ciona intestinalis71.977e-73 244
LLPS-Xet-2053Xenopus tropicalis71.970.01138
LLPS-Sus-0095Sus scrofa71.850.01144
LLPS-Lac-0253Latimeria chalumnae71.680.01110
LLPS-Pes-1606Pelodiscus sinensis71.610.01164
LLPS-Leo-0083Lepisosteus oculatus71.430.01163
LLPS-Dar-0410Danio rerio71.350.01195
LLPS-Ten-1168Tetraodon nigroviridis71.150.01169
LLPS-Xim-0263Xiphophorus maculatus71.060.01189
LLPS-Orn-0710Oreochromis niloticus71.060.01187
LLPS-Gaa-2825Gasterosteus aculeatus71.010.01167
LLPS-Scf-1455Scleropages formosus70.940.01166
LLPS-Pof-0428Poecilia formosa70.930.01188
LLPS-Icp-1092Ictalurus punctatus70.830.01167
LLPS-Scm-1172Scophthalmus maximus70.410.01172
LLPS-Asm-0768Astyanax mexicanus70.280.01167
LLPS-Cae-0251Caenorhabditis elegans70.120.01145
LLPS-Orl-1602Oryzias latipes70.030.01170
LLPS-Mod-2068Monodelphis domestica69.680.01095
LLPS-Aon-4192Aotus nancymaae69.550.01110
LLPS-Caj-3740Callithrix jacchus69.550.01108
LLPS-Anc-1195Anolis carolinensis69.140.01112
LLPS-Tar-3115Takifugu rubripes68.910.01118
LLPS-Sol-1026Solanum lycopersicum68.850.01129
LLPS-Cym-0486Cyanidioschyzon merolae68.720.01117
LLPS-Pug-0516Puccinia graminis68.630.01266
LLPS-Sot-0048Solanum tuberosum68.470.01121
LLPS-Gas-0207Galdieria sulphuraria68.390.01139
LLPS-Brn-2230Brassica napus68.340.01128
LLPS-Brr-0945Brassica rapa68.340.01128
LLPS-Nia-2255Nicotiana attenuata68.340.01115
LLPS-Bro-1004Brassica oleracea68.210.01127
LLPS-Orp-0975Oryza punctata68.210.01122
LLPS-Php-1743Physcomitrella patens68.120.01130
LLPS-Prp-0770Prunus persica68.120.01120
LLPS-Ori-1737Oryza indica68.080.01122
LLPS-Orni-1516Oryza nivara68.080.01122
LLPS-Org-0079Oryza glaberrima68.080.01122
LLPS-Ors-0214Oryza sativa68.080.01122
LLPS-Kop-1310Komagataella pastoris67.910.01276
LLPS-Art-0549Arabidopsis thaliana67.850.01142
LLPS-Tra-0525Triticum aestivum67.740.01108
LLPS-Pot-2009Populus trichocarpa67.730.01108
LLPS-Lep-0404Leersia perrieri67.70.01118
LLPS-Thc-1803Theobroma cacao67.70.01112
LLPS-Brd-1045Brachypodium distachyon67.650.01113
LLPS-Coc-2005Corchorus capsularis67.610.01036
LLPS-Anp-0289Anas platyrhynchos67.590.01052
LLPS-Cus-0213Cucumis sativus67.570.01123
LLPS-Drm-0660Drosophila melanogaster67.540.01118
LLPS-Chr-1485Chlamydomonas reinhardtii67.470.01108
LLPS-Gor-1987Gossypium raimondii67.440.01108
LLPS-Mae-0871Manihot esculenta67.440.01109
LLPS-Chc-0069Chondrus crispus67.360.01103
LLPS-Sei-1274Setaria italica67.310.01115
LLPS-Vir-0503Vigna radiata67.310.01109
LLPS-Hea-0884Helianthus annuus67.310.01117
LLPS-Orm-1186Oryza meridionalis67.310.01109
LLPS-Orgl-0764Oryza glumaepatula67.180.01107
LLPS-Glm-0576Glycine max67.180.01110
LLPS-Phv-0337Phaseolus vulgaris67.180.01107
LLPS-Arl-1422Arabidopsis lyrata67.130.01128
LLPS-Zem-1719Zea mays67.090.01115
LLPS-Via-0643Vigna angularis67.050.01105
LLPS-Hov-0544Hordeum vulgare67.050.01100
LLPS-Sem-0113Selaginella moellendorffii67.050.01122
LLPS-Orb-0351Oryza barthii67.050.01104
LLPS-Orr-1420Oryza rufipogon67.050.01104
LLPS-Amt-1028Amborella trichopoda67.050.01120
LLPS-Met-0771Medicago truncatula66.970.01119
LLPS-Sob-0579Sorghum bicolor66.960.01119
LLPS-Viv-0425Vitis vinifera66.710.01107
LLPS-Mua-1498Musa acuminata66.540.01126
LLPS-Osl-0526Ostreococcus lucimarinus66.450.01104
LLPS-Miv-0756Microbotryum violaceum66.270.01231
LLPS-Tru-0431Triticum urartu65.510.01093
LLPS-Orbr-0080Oryza brachyantha65.290.01095
LLPS-Crn-1223Cryptococcus neoformans65.230.01218
LLPS-Cis-0728Ciona savignyi63.570.01127
LLPS-Meg-0334Meleagris gallopavo62.660.0 962
LLPS-Dac-0141Daucus carota61.00.0 959
LLPS-Put-0270Puccinia triticina60.260.01087