• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Fus-0220
NECHADRAFT_78814

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ribonucleoside-diphosphate reductase
Gene Name: NECHADRAFT_78814
Ensembl Gene: NechaG78814
Ensembl Protein: NechaP78814
Organism: Fusarium solani
Taxa ID: 660122
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblNechaT78814NechaP78814
UniProtC7YPN4, C7YPN4_NECH7
GeneBankGG698898EEU45879.1
RefSeqXM_003051546.1XP_003051592.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFVRKRADNL  SDGRQERVQF  DKITARVSRL  CYGLDMDHVD  PVAITQKVIS  GVYGGVTTVQ  60
61    LDDLAAETAA  YMTVTHPDYA  ILAARIAVSN  LHKQTKKQWS  AVVSDLYHYV  NPKNDRASPM  120
121   ISQETYECVM  RHKEELDSAI  VYDRDFQYQY  FGFKTLERSY  LLKIDGKIVE  RPQHMIMRVA  180
181   VGIWGDNIER  VLETYNLMSS  KFFTHASPTL  FNAGTPQPQL  SSCFLVDMKE  DSIEGIYDTL  240
241   KTCAMISKMA  GGIGLNVHRI  RATGSYIAGT  NGTSNGVTPM  LRVFNNTARY  VDQGGNKRPG  300
301   AFAIYLEPWH  ADVFEFLDLR  KNHGKEEVRA  RDLFLALWIP  DLFMKRVEKN  GDWTLMCPNE  360
361   CPGLADCYGE  EFEALYEKYE  KAGKGRKTMK  AQKLWYAILE  AQTETGNPFM  LYKDHCNRKS  420
421   NQKNLGTIRS  SNLCTEIIEY  CAPDEVAVCN  LASLALPSFI  NYDEACYDFQ  KLHEVTQTVV  480
481   RNLNRIIDVN  HYPVPEARNS  NMRHRPIGVG  VQGLADAFLA  LRMPFESPEA  RELNKQIFET  540
541   IYHAALTASV  QLAKEEGPYS  TFKGSPASEG  ILQFDMWNVK  PSDLWDWESL  REQVKEHGTR  600
601   NSLLLAPMPT  ASTSQILGNN  ECFEPYTSNI  YQRRVLAGEF  QVVNPWLLKD  LVDMGLWSDS  660
661   MKNRIIAENG  SIQNIPNIPA  EVKALYKTVW  EISQRQVVQM  AADRGAFIDQ  SQSLNIHMKD  720
721   PTMGKITSMH  FAGWKLGLKT  GMYYLRTQAA  AAPIQFTVDQ  QALKVADANS  AQIRPLKKRA  780
781   PPAGSSYLIS  SPSSFSGASL  NGGRPAASGN  PRGQATIPGR  APSIKADPEE  GDSPKALPTE  840
841   PAEKIKEEEL  SLKKSEQSED  QDKDSEERER  DIYSDAVLQC  SIENPESCIM  CSG  893
Nucleotide CDS Sequence (FASTA)
1     ATGTTTGTCA  GAAAGCGCGC  TGATAATCTC  TCAGATGGAC  GCCAGGAGCG  CGTCCAGTTC  60
61    GACAAGATCA  CCGCCCGTGT  CTCGAGGCTC  TGTTACGGCC  TTGACATGGA  CCACGTTGAC  120
121   CCTGTTGCCA  TTACCCAGAA  GGTCATCTCG  GGTGTCTACG  GTGGTGTCAC  AACTGTCCAA  180
181   TTGGACGATC  TCGCTGCCGA  GACTGCGGCG  TACATGACCG  TCACCCACCC  CGACTACGCC  240
241   ATCCTGGCGG  CCCGTATCGC  CGTCTCCAAC  CTCCACAAGC  AGACCAAGAA  GCAATGGTCC  300
301   GCTGTCGTGA  GCGACCTCTA  CCACTATGTC  AACCCCAAGA  ACGACCGGGC  GTCGCCCATG  360
361   ATCTCCCAAG  AAACATATGA  GTGCGTCATG  CGACACAAGG  AGGAGCTAGA  CTCCGCCATT  420
421   GTCTATGACC  GTGACTTCCA  ATACCAATAC  TTTGGCTTCA  AGACTCTTGA  GCGATCCTAC  480
481   CTCCTGAAGA  TTGATGGCAA  GATTGTTGAG  CGCCCCCAGC  ACATGATCAT  GCGTGTGGCT  540
541   GTCGGCATCT  GGGGTGACAA  TATTGAGCGT  GTCCTCGAGA  CTTACAACCT  CATGTCGAGC  600
601   AAGTTCTTCA  CTCATGCCTC  CCCCACCCTC  TTCAACGCGG  GTACTCCCCA  GCCTCAGCTC  660
661   TCCTCATGCT  TCCTTGTCGA  CATGAAGGAG  GACAGTATTG  AGGGTATTTA  TGATACTCTC  720
721   AAGACTTGTG  CCATGATTTC  CAAGATGGCT  GGTGGTATTG  GCCTGAACGT  GCACCGAATC  780
781   CGTGCCACTG  GTTCTTACAT  CGCCGGTACC  AACGGTACCT  CCAACGGTGT  TACCCCCATG  840
841   CTCCGTGTCT  TCAACAACAC  TGCCCGATAC  GTCGATCAGG  GTGGCAACAA  GCGACCTGGT  900
901   GCCTTTGCCA  TCTACCTTGA  GCCCTGGCAC  GCAGATGTCT  TTGAGTTCCT  TGATCTGCGC  960
961   AAGAACCACG  GCAAGGAGGA  GGTCCGCGCT  CGCGACCTGT  TCCTGGCTCT  CTGGATTCCC  1020
1021  GATCTCTTCA  TGAAACGTGT  CGAGAAGAAC  GGTGACTGGA  CTCTCATGTG  TCCCAACGAG  1080
1081  TGTCCCGGCC  TCGCCGACTG  CTACGGTGAG  GAGTTCGAGG  CTCTGTACGA  GAAGTATGAG  1140
1141  AAGGCCGGTA  AGGGTCGCAA  GACCATGAAG  GCTCAGAAGC  TCTGGTATGC  CATCCTCGAG  1200
1201  GCTCAGACCG  AGACTGGTAA  CCCCTTCATG  CTCTACAAGG  ATCACTGCAA  CCGCAAGAGC  1260
1261  AACCAGAAGA  ACCTGGGTAC  CATTCGCAGC  TCCAACCTGT  GCACTGAGAT  CATCGAGTAC  1320
1321  TGTGCCCCTG  ATGAGGTTGC  TGTCTGCAAC  CTTGCCTCCC  TCGCCCTTCC  CTCTTTCATC  1380
1381  AACTACGACG  AGGCGTGCTA  TGACTTCCAG  AAGCTGCACG  AGGTCACACA  GACTGTCGTT  1440
1441  CGCAACCTGA  ACAGGATCAT  CGATGTGAAC  CACTACCCCG  TTCCTGAAGC  TCGCAACAGC  1500
1501  AACATGCGAC  ACCGACCCAT  TGGTGTCGGT  GTCCAAGGTC  TTGCCGATGC  TTTCCTTGCT  1560
1561  CTGCGCATGC  CTTTCGAGTC  TCCTGAGGCT  CGAGAGCTGA  ACAAGCAGAT  CTTTGAGACC  1620
1621  ATCTACCATG  CTGCCCTTAC  TGCTTCCGTG  CAGCTCGCCA  AGGAGGAGGG  TCCCTACTCT  1680
1681  ACCTTCAAGG  GCTCTCCTGC  CTCTGAGGGT  ATTCTCCAGT  TCGACATGTG  GAACGTGAAG  1740
1741  CCCTCTGACC  TCTGGGACTG  GGAGTCTCTC  AGGGAGCAGG  TCAAGGAGCA  TGGTACCCGC  1800
1801  AACAGTCTGC  TGCTTGCCCC  CATGCCCACT  GCCAGCACTT  CGCAGATCCT  GGGTAACAAC  1860
1861  GAGTGCTTCG  AGCCTTACAC  CTCCAACATC  TACCAGCGTC  GTGTCCTCGC  TGGCGAGTTC  1920
1921  CAGGTCGTTA  ACCCCTGGTT  GCTCAAGGAT  CTCGTCGATA  TGGGCCTGTG  GTCGGATTCC  1980
1981  ATGAAGAACC  GAATCATTGC  TGAGAACGGT  TCCATCCAGA  ACATCCCCAA  TATCCCCGCT  2040
2041  GAGGTCAAGG  CTCTCTACAA  GACCGTTTGG  GAGATTTCCC  AGCGCCAGGT  CGTCCAGATG  2100
2101  GCGGCCGACC  GAGGTGCCTT  CATTGATCAG  TCCCAGTCTC  TCAACATCCA  CATGAAGGAC  2160
2161  CCCACCATGG  GCAAGATCAC  CAGCATGCAC  TTTGCCGGCT  GGAAGCTCGG  TCTGAAGACG  2220
2221  GGCATGTACT  ACCTGCGAAC  GCAGGCTGCC  GCTGCTCCCA  TTCAGTTCAC  TGTCGATCAG  2280
2281  CAAGCTCTCA  AGGTTGCCGA  CGCCAACTCG  GCCCAGATCC  GACCTCTGAA  GAAGCGCGCT  2340
2341  CCTCCCGCCG  GCTCCAGCTA  TCTGATTTCG  TCGCCCTCGT  CCTTTTCTGG  GGCCTCTCTG  2400
2401  AACGGAGGCA  GGCCCGCCGC  CTCTGGCAAC  CCCCGAGGCC  AGGCTACTAT  TCCCGGCCGG  2460
2461  GCACCTTCCA  TCAAGGCTGA  CCCCGAGGAG  GGTGACAGCC  CCAAGGCCCT  CCCTACCGAG  2520
2521  CCTGCTGAAA  AGATCAAGGA  GGAGGAACTG  AGCCTCAAGA  AGAGCGAGCA  GTCCGAGGAT  2580
2581  CAGGACAAGG  ATAGCGAGGA  ACGTGAGCGG  GACATCTACT  CTGATGCCGT  CCTACAGTGT  2640
2641  AGCATTGAGA  ACCCCGAGTC  CTGCATCATG  TGCAGTGGCT  GA  2682

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
DNA replication
Nucleotide-binding
Oxidoreductase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
ATP binding
Molecular Function
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Biological Process
DNA replication

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fuo-1268Fusarium oxysporum95.190.01051
LLPS-Fuv-1027Fusarium verticillioides91.460.01667
LLPS-Cog-0042Colletotrichum gloeosporioides86.060.01585
LLPS-Trv-1088Trichoderma virens86.040.01588
LLPS-Coo-0064Colletotrichum orbiculare85.380.01568
LLPS-Trr-0172Trichoderma reesei85.30.01569
LLPS-Cogr-1211Colletotrichum graminicola84.910.01575
LLPS-Ved-1342Verticillium dahliae84.140.01566
LLPS-Beb-0628Beauveria bassiana84.080.01583
LLPS-Pytr-0520Pyrenophora triticirepentis82.490.01365
LLPS-Map-0472Magnaporthe poae82.290.01516
LLPS-Mao-1183Magnaporthe oryzae81.620.01538
LLPS-Aso-0344Aspergillus oryzae81.310.01368
LLPS-Zyt-0984Zymoseptoria tritici80.750.01323
LLPS-Gag-0489Gaeumannomyces graminis79.980.01507
LLPS-Pyt-0593Pyrenophora teres76.340.01404
LLPS-Nec-0887Neurospora crassa76.140.01445
LLPS-Asfu-0249Aspergillus fumigatus75.480.01399
LLPS-Lem-0078Leptosphaeria maculans75.410.01407
LLPS-Scc-0602Schizosaccharomyces cryophilus75.390.01224
LLPS-Asc-0241Aspergillus clavatus75.170.01397
LLPS-Nef-0761Neosartorya fischeri75.170.01400
LLPS-Ast-0605Aspergillus terreus75.060.01384
LLPS-Asni-1076Aspergillus niger75.00.01383
LLPS-Scj-0125Schizosaccharomyces japonicus75.00.01209
LLPS-Phn-0557Phaeosphaeria nodorum74.840.01397
LLPS-Asn-0959Aspergillus nidulans74.770.01390
LLPS-Blg-0395Blumeria graminis74.70.01384
LLPS-Asf-0219Aspergillus flavus74.610.01388
LLPS-Rhb-3940Rhinopithecus bieti74.250.0 857
LLPS-Yal-0520Yarrowia lipolytica74.030.01266
LLPS-Tum-1231Tuber melanosporum74.020.01358
LLPS-Usm-1209Ustilago maydis73.830.01237
LLPS-Abg-0007Absidia glauca73.820.01223
LLPS-Scp-0347Schizosaccharomyces pombe73.590.01222
LLPS-Mup-0397Mustela putorius furo73.550.0 776
LLPS-Spr-0372Sporisorium reilianum73.530.01250
LLPS-Miv-0756Microbotryum violaceum73.430.01218
LLPS-Sah-1131Sarcophilus harrisii73.160.01182
LLPS-Tag-1934Taeniopygia guttata72.910.0 626
LLPS-Otg-0341Otolemur garnettii72.630.01158
LLPS-Ran-2689Rattus norvegicus72.610.01172
LLPS-Mam-1882Macaca mulatta72.610.01161
LLPS-Fud-0039Fukomys damarensis72.570.01160
LLPS-Aim-1490Ailuropoda melanoleuca72.530.0 737
LLPS-Cap-1701Cavia porcellus72.470.01164
LLPS-Eqc-2018Equus caballus72.360.01110
LLPS-Mum-3781Mus musculus72.350.01168
LLPS-Fec-2350Felis catus72.350.01165
LLPS-Ict-1734Ictidomys tridecemlineatus72.350.01167
LLPS-Ora-2690Ornithorhynchus anatinus72.330.01162
LLPS-Mea-0066Mesocricetus auratus72.250.01165
LLPS-Caf-1790Canis familiaris72.210.01164
LLPS-Chs-0056Chlorocebus sabaeus72.080.01160
LLPS-Maf-0219Macaca fascicularis72.080.01160
LLPS-Cea-0640Cercocebus atys72.080.01160
LLPS-Myl-2322Myotis lucifugus72.080.01165
LLPS-Ova-0748Ovis aries72.080.01165
LLPS-Mal-0197Mandrillus leucophaeus72.080.01160
LLPS-Paa-2849Papio anubis72.080.01160
LLPS-Man-0975Macaca nemestrina72.080.01160
LLPS-Dio-1786Dipodomys ordii71.990.01164
LLPS-Sus-0095Sus scrofa71.980.01144
LLPS-Gog-0394Gorilla gorilla71.950.01160
LLPS-Bot-3557Bos taurus71.950.01161
LLPS-Fia-3000Ficedula albicollis71.950.01164
LLPS-Orc-1961Oryctolagus cuniculus71.950.01160
LLPS-Pat-4006Pan troglodytes71.950.01160
LLPS-Pap-0215Pan paniscus71.950.01160
LLPS-Hos-0396Homo sapiens71.950.01160
LLPS-Loa-1547Loxodonta africana71.950.01162
LLPS-Nol-1189Nomascus leucogenys71.950.01159
LLPS-Poa-1028Pongo abelii71.950.01160
LLPS-Dos-0469Dothistroma septosporum71.80.01354
LLPS-Tut-1312Tursiops truncatus71.690.01159
LLPS-Pes-1606Pelodiscus sinensis71.690.01157
LLPS-Cas-3251Carlito syrichta71.690.01159
LLPS-Sac-1126Saccharomyces cerevisiae71.360.01216
LLPS-Gaga-1111Gallus gallus71.150.01174
LLPS-Lac-0253Latimeria chalumnae71.00.01105
LLPS-Xet-2053Xenopus tropicalis70.980.01129
LLPS-Dar-0410Danio rerio70.810.01172
LLPS-Leo-0083Lepisosteus oculatus70.70.01154
LLPS-Icp-1092Ictalurus punctatus70.410.01166
LLPS-Ten-1168Tetraodon nigroviridis70.290.01157
LLPS-Scf-1455Scleropages formosus69.90.01150
LLPS-Cae-0251Caenorhabditis elegans69.890.01133
LLPS-Xim-0263Xiphophorus maculatus69.860.01176
LLPS-Cii-0533Ciona intestinalis69.71e-72 243
LLPS-Pof-0428Poecilia formosa69.60.01173
LLPS-Caj-3740Callithrix jacchus69.290.01104
LLPS-Aon-4192Aotus nancymaae69.290.01104
LLPS-Orn-0710Oreochromis niloticus69.220.01164
LLPS-Anc-1195Anolis carolinensis69.060.01101
LLPS-Gaa-2825Gasterosteus aculeatus69.040.01149
LLPS-Asm-0768Astyanax mexicanus68.970.01148
LLPS-Scm-1172Scophthalmus maximus68.970.01153
LLPS-Mod-2068Monodelphis domestica68.960.01085
LLPS-Orl-1602Oryzias latipes68.840.01156
LLPS-Pug-0516Puccinia graminis68.760.01258
LLPS-Tar-3115Takifugu rubripes67.930.01108
LLPS-Chc-0069Chondrus crispus67.820.01099
LLPS-Art-0549Arabidopsis thaliana67.770.01131
LLPS-Nia-0254Nicotiana attenuata67.650.01110
LLPS-Php-1743Physcomitrella patens67.550.01130
LLPS-Brn-2230Brassica napus67.520.01118
LLPS-Brr-0945Brassica rapa67.520.01118
LLPS-Kop-1310Komagataella pastoris67.480.01273
LLPS-Mel-0824Melampsora laricipopulina67.440.01253
LLPS-Gas-0207Galdieria sulphuraria67.40.01126
LLPS-Sol-1026Solanum lycopersicum67.390.01107
LLPS-Sot-0048Solanum tuberosum67.390.01108
LLPS-Bro-1004Brassica oleracea67.390.01117
LLPS-Cym-0486Cyanidioschyzon merolae67.370.01106
LLPS-Arl-1422Arabidopsis lyrata67.180.01120
LLPS-Anp-0289Anas platyrhynchos67.110.01049
LLPS-Drm-0660Drosophila melanogaster67.020.01114
LLPS-Coc-2005Corchorus capsularis66.90.01029
LLPS-Asg-0184Ashbya gossypii66.810.01264
LLPS-Mua-1498Musa acuminata66.750.01116
LLPS-Cus-0213Cucumis sativus66.750.01108
LLPS-Chr-1485Chlamydomonas reinhardtii66.710.01093
LLPS-Thc-1803Theobroma cacao66.50.01099
LLPS-Tra-0525Triticum aestivum66.50.01097
LLPS-Amt-1028Amborella trichopoda66.50.01104
LLPS-Pot-2009Populus trichocarpa66.410.01095
LLPS-Sei-1274Setaria italica66.370.01103
LLPS-Vir-0503Vigna radiata66.370.01099
LLPS-Sob-0579Sorghum bicolor66.370.01102
LLPS-Orp-0975Oryza punctata66.330.01105
LLPS-Gor-1987Gossypium raimondii66.290.01098
LLPS-Met-0771Medicago truncatula66.240.01113
LLPS-Zem-1719Zea mays66.240.01100
LLPS-Orni-1516Oryza nivara66.20.01105
LLPS-Glm-0576Glycine max66.20.01090
LLPS-Ori-1737Oryza indica66.20.01105
LLPS-Brd-1045Brachypodium distachyon66.20.01095
LLPS-Ors-0214Oryza sativa66.20.01105
LLPS-Org-0079Oryza glaberrima66.20.01105
LLPS-Phv-0337Phaseolus vulgaris66.160.01093
LLPS-Hea-0884Helianthus annuus65.990.01107
LLPS-Hov-0544Hordeum vulgare65.980.01082
LLPS-Via-0643Vigna angularis65.980.01085
LLPS-Prp-0770Prunus persica65.870.01097
LLPS-Mae-0871Manihot esculenta65.860.01092
LLPS-Lep-0404Leersia perrieri65.820.01102
LLPS-Sem-0113Selaginella moellendorffii65.730.01103
LLPS-Osl-0526Ostreococcus lucimarinus65.530.01098
LLPS-Orm-1186Oryza meridionalis65.320.01090
LLPS-Orb-0351Oryza barthii65.190.01088
LLPS-Orgl-0764Oryza glumaepatula65.190.01088
LLPS-Orr-1420Oryza rufipogon65.060.01086
LLPS-Crn-1223Cryptococcus neoformans64.920.01219
LLPS-Viv-0425Vitis vinifera64.780.01088
LLPS-Tru-0431Triticum urartu64.340.01082
LLPS-Orbr-0080Oryza brachyantha63.630.01078
LLPS-Cis-0728Ciona savignyi62.80.01126
LLPS-Meg-0334Meleagris gallopavo61.620.0 958
LLPS-Put-0270Puccinia triticina61.110.01087
LLPS-Dac-0141Daucus carota59.970.0 944