LLPS-Sus-3404
MARK4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Non-specific serine/threonine protein kinase |
| Gene Name: | MARK4 |
| Ensembl Gene: | ENSSSCG00000022538.2 |
| Ensembl Protein: | ENSSSCP00000054889.1 |
| Organism: | Sus scrofa |
| Taxa ID: | 9823 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSSSCT00000059019.1 | ENSSSCP00000054889.1 |
| Ensembl | ENSSSCT00000032120.2 | ENSSSCP00000019345.2 |
| UniProt | A0A287BEB6, A0A287BEB6_PIG | |
| GeneBank | AEMK02000041 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSSRTAMAPG NDRNSDTHGT LGSGRSSDKG PSWSSRSLGA RCRNSIASCP EEQPHVGNYR 60 61 LLRTIGKGNF AKVKLARHIL TGREVAIKII DKTQLNPSSL QKLFREVRIM KGLNHPNIVK 120 121 LFEVIETEKT LYLVMEYASA GEVFDYLVSH GRMKEKEARA KFRQIVSAVH YCHQKNIVHR 180 181 DLKAENLLLD AEANIKIADF GFSNEFTLGS KLDTFCGSPP YAAPELFQGK KYDGPEVDIW 240 241 SLGVILYTLV SGSLPFDGHN LKELRERVLR GKYRVPFYMS TDCESILRRF LVLNPAKRCT 300 301 LEQIMKDKWI NIGYEGEELK PYTEPEEDFG DTKRIEVMVG MGYTREEIKE ALTSQKYNEV 360 361 TATYLLLGRK TEEGGDRGAP GLALARVRAP SDTTNGTSSS KGTSHSKGQR SSSSTYHRQR 420 421 RHSDFCGPSP APLHPKRSPT STGEAELKEE RLPGRKASCS AAGSGSRGLP PSSPMVSSAH 480 481 NPNKAEIPER RKDSTSTPNN LPPSMMTRRN TYVCTERPGA ERPSLLPNGK ENSSGTPRVP 540 541 PASPSSHSLA PPSGERSRLA RGSTIRSTFH GGQVRDRRAG GGGGGGVQNG PPASPTLAHE 600 601 ATPLPTGRPR PTTNLFTKLT SKLTRRVTDE PERIGGPEVT SCHLPWDQTE TAPRLLRFPW 660 661 SVKLTSSRPP EALMAALRQA TAAARCRCRQ PQPFLLACLH GGAGGPEPLS HFEVEVCQLP 720 721 RPGLRGVLFR RVAGTALAFR TLVTRISNDL EL 752 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTTCGC GGACGGCGAT GGCCCCGGGC AACGATCGGA ACTCGGACAC GCATGGCACC 60 61 CTGGGCAGTG GCCGCTCCTC TGACAAGGGA CCGTCCTGGT CCAGCCGCTC CCTGGGTGCC 120 121 CGCTGCCGGA ACTCCATCGC CTCCTGTCCT GAGGAGCAGC CACACGTGGG CAACTACCGC 180 181 CTGCTGAGGA CCATTGGGAA GGGCAACTTT GCCAAAGTCA AGCTGGCCCG GCACATCCTT 240 241 ACCGGCCGGG AGGTCGCCAT CAAGATTATC GACAAAACCC AGCTGAACCC CAGCAGCCTG 300 301 CAGAAACTGT TCCGAGAAGT CCGCATCATG AAGGGCCTGA ACCACCCCAA CATTGTGAAG 360 361 CTCTTCGAGG TCATCGAGAC AGAGAAGACG CTGTACCTGG TGATGGAATA CGCAAGTGCT 420 421 GGAGAAGTGT TTGACTACCT CGTGTCGCAC GGCCGCATGA AGGAGAAGGA AGCTCGAGCC 480 481 AAGTTCCGAC AGATTGTGTC GGCTGTGCAC TACTGTCACC AGAAAAACAT TGTCCACAGG 540 541 GACCTGAAGG CGGAGAACCT CTTGCTGGAC GCCGAGGCCA ACATCAAGAT CGCCGACTTT 600 601 GGCTTCAGCA ATGAGTTCAC ACTGGGCTCG AAGCTGGACA CATTCTGCGG GAGCCCCCCG 660 661 TACGCCGCCC CGGAGCTGTT CCAGGGCAAG AAGTACGACG GGCCGGAGGT GGACATCTGG 720 721 AGCCTGGGCG TTATCCTGTA CACCCTCGTC AGCGGCTCCC TGCCCTTCGA CGGGCACAAC 780 781 CTCAAGGAGC TGCGGGAGCG AGTCCTCAGA GGGAAGTACC GGGTCCCTTT CTACATGTCA 840 841 ACAGACTGTG AGAGCATCCT GCGGAGATTT TTGGTGCTGA ATCCAGCTAA ACGCTGTACT 900 901 CTGGAGCAAA TCATGAAAGA CAAGTGGATC AACATCGGCT ACGAGGGCGA GGAGCTGAAG 960 961 CCATACACGG AGCCTGAGGA GGACTTCGGG GACACCAAAC GAATTGAGGT GATGGTGGGT 1020 1021 ATGGGCTACA CGCGGGAAGA AATCAAAGAG GCCTTGACCA GCCAGAAGTA CAACGAAGTG 1080 1081 ACCGCCACCT ACCTCCTGCT GGGCAGGAAG ACTGAGGAGG GTGGGGACCG GGGCGCCCCG 1140 1141 GGGCTGGCCC TGGCACGGGT GCGGGCGCCC AGCGACACCA CCAATGGAAC AAGCTCCAGC 1200 1201 AAAGGCACCA GCCACAGCAA AGGGCAGCGG AGCTCCTCCT CCACCTACCA CCGCCAGCGC 1260 1261 AGGCACAGCG ACTTCTGTGG TCCGTCTCCC GCACCCCTGC ACCCCAAGCG CAGCCCAACC 1320 1321 AGCACAGGGG AGGCGGAACT GAAGGAGGAG CGCCTGCCAG GCCGGAAGGC AAGCTGCAGT 1380 1381 GCTGCTGGGA GCGGGAGCCG AGGGCTGCCC CCCTCCAGCC CCATGGTCAG CAGTGCCCAC 1440 1441 AACCCCAACA AGGCAGAGAT CCCAGAGCGA CGGAAGGACA GCACGAGCAC CCCTAACAAC 1500 1501 CTCCCTCCCA GCATGATGAC CCGCAGAAAC ACCTATGTTT GCACAGAACG CCCAGGGGCT 1560 1561 GAGCGCCCGT CCCTGTTGCC AAATGGCAAA GAAAACAGCT CGGGTACCCC ACGGGTGCCC 1620 1621 CCCGCCTCCC CCTCCAGTCA CAGCCTGGCT CCCCCATCGG GGGAGCGGAG CCGCCTGGCA 1680 1681 CGCGGCTCCA CCATCCGCAG CACCTTCCAC GGTGGCCAGG TCCGAGACAG GCGGGCAGGG 1740 1741 GGCGGGGGAG GTGGGGGCGT GCAGAACGGG CCCCCCGCCT CTCCCACCCT GGCCCACGAG 1800 1801 GCCACGCCCC TGCCCACTGG GCGGCCCCGC CCCACCACCA ACCTCTTCAC CAAGCTGACC 1860 1861 TCCAAACTGA CCCGAAGGGT TACCCTCGAT CCCTCTAAAC GGCAGAACTC TAACCGCTGC 1920 1921 GTTTCAGGCG CCTCTCTGCC CCAGGGATCC AAGATCAGGT CACAGACGAA CCTGAGAGAA 1980 1981 TCGGGGGACC TGAGGTCACA AGTTGCCATC TACCTTGGGA TCAAACGGAA ACCGCCCCCC 2040 2041 GGCTGCTCCG ATTCCCCTGG AGTGTGA 2067 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Bot-2437 | Bos taurus | 99.86 | 0.0 | 1259 |
| LLPS-Cea-2813 | Cercocebus atys | 99.59 | 0.0 | 1260 |
| LLPS-Maf-0103 | Macaca fascicularis | 99.34 | 0.0 | 1290 |
| LLPS-Aon-3096 | Aotus nancymaae | 99.34 | 0.0 | 1292 |
| LLPS-Paa-0834 | Papio anubis | 99.34 | 0.0 | 1290 |
| LLPS-Eqc-3133 | Equus caballus | 99.32 | 0.0 | 1249 |
| LLPS-Ova-1696 | Ovis aries | 99.28 | 1e-68 | 246 |
| LLPS-Pap-4698 | Pan paniscus | 99.2 | 0.0 | 1288 |
| LLPS-Pat-3865 | Pan troglodytes | 99.2 | 0.0 | 1288 |
| LLPS-Mam-4391 | Macaca mulatta | 99.2 | 0.0 | 1288 |
| LLPS-Otg-3161 | Otolemur garnettii | 99.07 | 0.0 | 1285 |
| LLPS-Hos-2414 | Homo sapiens | 99.07 | 0.0 | 1289 |
| LLPS-Fec-0779 | Felis catus | 98.94 | 0.0 | 1285 |
| LLPS-Mup-3382 | Mustela putorius furo | 98.58 | 0.0 | 1082 |
| LLPS-Ran-3079 | Rattus norvegicus | 98.01 | 0.0 | 1279 |
| LLPS-Aim-3618 | Ailuropoda melanoleuca | 97.94 | 0.0 | 988 |
| LLPS-Mum-3604 | Mus musculus | 97.87 | 0.0 | 1283 |
| LLPS-Cap-1727 | Cavia porcellus | 97.61 | 0.0 | 1276 |
| LLPS-Poa-4605 | Pongo abelii | 97.07 | 0.0 | 1249 |
| LLPS-Chs-3352 | Chlorocebus sabaeus | 96.95 | 0.0 | 1254 |
| LLPS-Dio-3478 | Dipodomys ordii | 95.98 | 0.0 | 1066 |
| LLPS-Caf-1580 | Canis familiaris | 95.74 | 0.0 | 1253 |
| LLPS-Man-1023 | Macaca nemestrina | 95.69 | 0.0 | 1242 |
| LLPS-Caj-3264 | Callithrix jacchus | 95.53 | 0.0 | 1276 |
| LLPS-Loa-1496 | Loxodonta africana | 94.02 | 0.0 | 1194 |
| LLPS-Fud-4090 | Fukomys damarensis | 93.92 | 0.0 | 910 |
| LLPS-Nol-1467 | Nomascus leucogenys | 93.55 | 0.0 | 1007 |
| LLPS-Cas-4009 | Carlito syrichta | 91.84 | 9e-21 | 101 |
| LLPS-Mea-3766 | Mesocricetus auratus | 90.96 | 0.0 | 1144 |
| LLPS-Myl-1394 | Myotis lucifugus | 85.64 | 0.0 | 1077 |
| LLPS-Anc-2478 | Anolis carolinensis | 83.49 | 0.0 | 592 |
| LLPS-Ere-0560 | Erinaceus europaeus | 82.88 | 0.0 | 594 |
| LLPS-Orn-3864 | Oreochromis niloticus | 78.67 | 0.0 | 589 |
| LLPS-Gog-1134 | Gorilla gorilla | 77.96 | 0.0 | 600 |
| LLPS-Sah-2182 | Sarcophilus harrisii | 77.4 | 0.0 | 922 |
| LLPS-Pof-2941 | Poecilia formosa | 76.42 | 0.0 | 801 |
| LLPS-Ten-0184 | Tetraodon nigroviridis | 76.27 | 0.0 | 756 |
| LLPS-Gaa-0403 | Gasterosteus aculeatus | 75.97 | 0.0 | 586 |
| LLPS-Pes-1866 | Pelodiscus sinensis | 73.82 | 0.0 | 600 |
| LLPS-Cii-0600 | Ciona intestinalis | 73.05 | 6e-174 | 509 |
| LLPS-Dar-3056 | Danio rerio | 72.31 | 0.0 | 874 |
| LLPS-Icp-1528 | Ictalurus punctatus | 69.83 | 0.0 | 706 |
| LLPS-Gaga-2857 | Gallus gallus | 69.35 | 0.0 | 723 |
| LLPS-Tag-3412 | Taeniopygia guttata | 69.35 | 0.0 | 719 |
| LLPS-Anp-2229 | Anas platyrhynchos | 69.31 | 0.0 | 636 |
| LLPS-Meg-2502 | Meleagris gallopavo | 69.2 | 0.0 | 685 |
| LLPS-Lac-3387 | Latimeria chalumnae | 69.16 | 0.0 | 709 |
| LLPS-Rhb-3507 | Rhinopithecus bieti | 68.78 | 0.0 | 603 |
| LLPS-Xet-3697 | Xenopus tropicalis | 68.6 | 0.0 | 698 |
| LLPS-Ict-0973 | Ictidomys tridecemlineatus | 68.6 | 0.0 | 710 |
| LLPS-Fia-3418 | Ficedula albicollis | 68.54 | 0.0 | 567 |
| LLPS-Xim-1478 | Xiphophorus maculatus | 67.66 | 0.0 | 678 |
| LLPS-Tut-1365 | Tursiops truncatus | 67.52 | 0.0 | 625 |
| LLPS-Scm-3270 | Scophthalmus maximus | 67.03 | 0.0 | 673 |
| LLPS-Mod-1446 | Monodelphis domestica | 66.85 | 0.0 | 701 |
| LLPS-Cae-0220 | Caenorhabditis elegans | 66.49 | 2e-172 | 535 |
| LLPS-Tar-2194 | Takifugu rubripes | 65.63 | 0.0 | 897 |
| LLPS-Leo-1888 | Lepisosteus oculatus | 65.22 | 0.0 | 915 |
| LLPS-Drm-0398 | Drosophila melanogaster | 65.18 | 7e-149 | 459 |
| LLPS-Orl-3229 | Oryzias latipes | 64.98 | 0.0 | 891 |
| LLPS-Urm-0247 | Ursus maritimus | 64.44 | 2e-96 | 320 |
| LLPS-Asm-2102 | Astyanax mexicanus | 64.29 | 0.0 | 590 |
| LLPS-Ora-1247 | Ornithorhynchus anatinus | 61.06 | 0.0 | 824 |
| LLPS-Orc-4371 | Oryctolagus cuniculus | 59.71 | 0.0 | 824 |
| LLPS-Scf-0257 | Scleropages formosus | 58.88 | 0.0 | 802 |
| LLPS-Cis-1934 | Ciona savignyi | 57.75 | 6e-140 | 438 |
| LLPS-Mal-1727 | Mandrillus leucophaeus | 55.0 | 4e-113 | 371 |
| LLPS-Brr-2260 | Brassica rapa | 45.74 | 1e-84 | 284 |
| LLPS-Phv-2505 | Phaseolus vulgaris | 45.69 | 2e-84 | 284 |
| LLPS-Brn-1105 | Brassica napus | 45.54 | 2e-84 | 284 |
| LLPS-Bro-2943 | Brassica oleracea | 45.54 | 2e-84 | 283 |
| LLPS-Arl-1065 | Arabidopsis lyrata | 44.97 | 1e-85 | 286 |
| LLPS-Art-2601 | Arabidopsis thaliana | 44.97 | 2e-86 | 289 |
| LLPS-Kop-0972 | Komagataella pastoris | 44.92 | 7e-85 | 286 |
| LLPS-Orbr-0158 | Oryza brachyantha | 44.76 | 4e-87 | 290 |
| LLPS-Orm-0713 | Oryza meridionalis | 44.76 | 2e-87 | 291 |
| LLPS-Sei-0362 | Setaria italica | 44.73 | 9e-86 | 288 |
| LLPS-Orni-0188 | Oryza nivara | 44.44 | 1e-86 | 292 |
| LLPS-Orb-2279 | Oryza barthii | 44.44 | 6e-87 | 291 |
| LLPS-Orgl-0300 | Oryza glumaepatula | 44.44 | 7e-87 | 293 |
| LLPS-Lep-2156 | Leersia perrieri | 44.44 | 2e-86 | 289 |
| LLPS-Ors-2364 | Oryza sativa | 44.44 | 5e-87 | 290 |
| LLPS-Zem-1597 | Zea mays | 44.44 | 3e-85 | 291 |
| LLPS-Orr-1376 | Oryza rufipogon | 44.44 | 5e-87 | 290 |
| LLPS-Sac-0308 | Saccharomyces cerevisiae | 43.03 | 9e-86 | 290 |
| LLPS-Nia-2028 | Nicotiana attenuata | 41.62 | 6e-85 | 285 |