LLPS-Dio-3478
Mark4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | MAP/microtubule affinity-regulating kinase 4 |
| Gene Name: | Mark4 |
| Ensembl Gene: | ENSDORG00000013282.2 |
| Ensembl Protein: | ENSDORP00000012491.2 |
| Organism: | Dipodomys ordii |
| Taxa ID: | 10020 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDORT00000013284.2 | ENSDORP00000012491.2 |
| UniProt | A0A1S3GJ95, A0A1S3GJ95_DIPOR | |
| RefSeq | , XM_013032628.1 | , XP_012888082.1, XP_012888082.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 LSSRRALYHL SHSHGTLGSG RSSDKGPSWS SRSLGARCRN SIASCPEEQP HVGNYRLLRT 60 61 IGKGNFAKVK LARHILTGRE VAIKIIDKTQ LNPSSLQKLF REVRIMKGLN HPNIVKLFEV 120 121 IETEKTLYLV MEYASAGEVF DYLVSHGRMK EKEARAKFRQ IVSAVHYCHQ KNIVHRDLKA 180 181 ENLLLDAEAN IKIADFGFSN EFTLGSKLDT FCGSPPYAAP ELFQGKKYDG PEVDIWSLGV 240 241 ILYTLVSGSL PFDGHNLKEL RERVLRGKYR VPFYMSTDCE SILRRFLVLN PAKRCTLEQI 300 301 MKDKWMNIGY EGEELKPYTE PEEDFGDTKR IEVMVGMGYT REEIKEALTS QKYNEVTATY 360 361 LLLGRKTEEG GDRGAPGLAL ARVRAPSDTT NGTSSSKSSS HSKGPRSSSS TYHRQRRHSD 420 421 FCGPSPAPLH PKRSPTSTGE AELKEERLPG RKASCSAAGS GSRGLPPSSP MVSSAHNPNK 480 481 AEIPERRKDS TSTPNNLPPS MMTRRNTYVC TERPGADRPS LLPNGKENSS GTPRVPPASP 540 541 SSHSLAPPSG ERSRLARGST IRSTFHGGQV RDRRAGGGGG GGVQNGPPAS PTLAHEASPL 600 601 PSGRPRPTTN LFTKLTSKLT RRVADEPERI GGPEVTRAQI TSLLEVPQDP SLSHFPAQLL 660 661 YPSLGPICQN LETRARRGCA CL 682 |
| Nucleotide CDS Sequence (FASTA) |
1 CTCAGCTCAA GGCGAGCGCT CTACCACTTG AGCCACAGCC ATGGCACCTT GGGCAGCGGA 60 61 CGGTCTTCAG ACAAGGGGCC ATCGTGGTCC AGCCGTTCCC TGGGCGCCCG CTGCCGGAAC 120 121 TCCATCGCCT CCTGTCCCGA GGAGCAGCCC CACGTAGGTA ACTACCGCCT GCTGCGGACC 180 181 ATCGGGAAAG GCAACTTTGC CAAGGTCAAG CTGGCTCGGC ACATCCTCAC AGGACGAGAG 240 241 GTCGCAATCA AGATCATTGA TAAAACCCAG TTGAACCCCA GCAGCCTGCA GAAGCTGTTC 300 301 CGAGAAGTCC GAATCATGAA GGGCCTAAAC CATCCCAACA TCGTGAAGCT CTTCGAAGTA 360 361 ATCGAGACAG AGAAGACACT CTACCTAGTG ATGGAATATG CAAGTGCCGG AGAAGTGTTT 420 421 GACTACCTCG TGTCCCATGG CCGCATGAAG GAGAAGGAAG CGCGAGCTAA ATTCCGACAG 480 481 ATTGTATCGG CTGTGCACTA CTGTCACCAG AAAAACATTG TCCACAGGGA CCTGAAGGCT 540 541 GAGAACCTCT TGCTGGATGC CGAAGCCAAC ATCAAGATCG CGGACTTCGG CTTCAGCAAC 600 601 GAGTTCACGC TGGGCTCGAA GCTGGACACC TTCTGCGGGA GCCCCCCGTA TGCCGCCCCT 660 661 GAGCTGTTCC AGGGCAAGAA GTACGATGGG CCCGAGGTGG ACATCTGGAG CCTCGGCGTC 720 721 ATCCTGTACA CCCTGGTCAG CGGCTCCCTG CCCTTTGACG GGCACAACCT CAAGGAGCTG 780 781 CGGGAGCGCG TGCTCAGAGG CAAGTACCGC GTCCCCTTCT ACATGTCCAC AGACTGTGAG 840 841 AGCATCCTGC GGAGATTCTT GGTGCTGAAC CCCGCTAAAC GCTGTACCCT TGAGCAAATC 900 901 ATGAAAGACA AATGGATGAA CATCGGCTAC GAGGGCGAGG AGTTGAAGCC ATACACGGAG 960 961 CCCGAGGAAG ACTTTGGGGA CACCAAACGG ATTGAGGTGA TGGTGGGCAT GGGCTACACC 1020 1021 CGGGAAGAAA TCAAAGAGGC CTTGACCAGC CAGAAGTACA ATGAAGTGAC CGCTACCTAC 1080 1081 CTCCTGCTGG GCAGGAAGAC TGAGGAGGGT GGGGATCGGG GCGCCCCTGG GCTGGCCCTG 1140 1141 GCACGGGTGC GGGCGCCCAG CGATACCACC AATGGCACGA GCTCCAGCAA AAGCAGCAGC 1200 1201 CACAGCAAGG GGCCGCGGAG CTCCTCGTCC ACCTACCACC GCCAGCGCAG GCACAGTGAC 1260 1261 TTTTGCGGCC CATCCCCTGC CCCCCTGCAC CCTAAACGCA GCCCGACCAG CACAGGGGAG 1320 1321 GCAGAGCTGA AGGAGGAGCG GCTGCCTGGC CGGAAGGCCA GCTGCAGCGC GGCGGGCAGC 1380 1381 GGGAGCCGAG GGCTGCCCCC TTCCAGCCCC ATGGTCAGCA GTGCCCACAA CCCCAACAAG 1440 1441 GCGGAGATCC CCGAGCGGCG GAAGGACAGC ACGAGCACCC CTAACAACCT TCCTCCCAGC 1500 1501 ATGATGACCC GCAGGAACAC CTACGTGTGC ACTGAGCGCC CTGGGGCCGA TCGCCCATCC 1560 1561 CTGTTGCCAA ATGGCAAAGA AAACAGCTCG GGCACCCCCC GGGTGCCCCC TGCCTCCCCC 1620 1621 TCCAGCCACA GCCTGGCCCC TCCATCCGGG GAACGGAGCC GCCTGGCACG GGGCTCCACC 1680 1681 ATCCGCAGCA CCTTCCACGG TGGCCAGGTC CGGGACCGGC GGGCAGGGGG CGGGGGTGGC 1740 1741 GGGGGTGTGC AGAACGGTCC TCCTGCCTCC CCCACGCTGG CCCACGAGGC TTCACCCCTG 1800 1801 CCCTCCGGGC GACCGCGCCC CACCACCAAC CTCTTTACCA AGCTGACCTC CAAACTGACC 1860 1861 CGCAGGGTCG CAGACGAACC TGAGAGAATC GGGGGACCTG AGGTCACAAG GGCCCAGATC 1920 1921 ACATCACTTC TTGAGGTGCC CCAGGACCCC TCACTCAGCC ATTTCCCTGC ACAACTCTTG 1980 1981 TACCCCTCAC TTGGGCCCAT ATGCCAGAAT CTAGAGACAA GAGCCAGGCG TGGCTGTGCA 2040 2041 TGCCTGTAA 2049 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Cea-2813 | Cercocebus atys | 96.42 | 0.0 | 1085 |
| LLPS-Mam-4391 | Macaca mulatta | 96.13 | 0.0 | 1087 |
| LLPS-Paa-0834 | Papio anubis | 96.13 | 0.0 | 1087 |
| LLPS-Maf-0103 | Macaca fascicularis | 96.13 | 0.0 | 1087 |
| LLPS-Bot-2437 | Bos taurus | 96.11 | 0.0 | 1083 |
| LLPS-Pat-3865 | Pan troglodytes | 95.98 | 0.0 | 1085 |
| LLPS-Pap-4698 | Pan paniscus | 95.98 | 0.0 | 1085 |
| LLPS-Sus-3404 | Sus scrofa | 95.98 | 0.0 | 1085 |
| LLPS-Hos-2414 | Homo sapiens | 95.82 | 0.0 | 1085 |
| LLPS-Mup-3382 | Mustela putorius furo | 95.73 | 0.0 | 1065 |
| LLPS-Eqc-3133 | Equus caballus | 95.52 | 0.0 | 1079 |
| LLPS-Ran-3079 | Rattus norvegicus | 95.34 | 0.0 | 1075 |
| LLPS-Aim-3618 | Ailuropoda melanoleuca | 95.13 | 0.0 | 944 |
| LLPS-Mum-3604 | Mus musculus | 95.03 | 0.0 | 1076 |
| LLPS-Aon-3096 | Aotus nancymaae | 94.7 | 0.0 | 1088 |
| LLPS-Otg-3161 | Otolemur garnettii | 94.24 | 0.0 | 1079 |
| LLPS-Fec-0779 | Felis catus | 93.94 | 0.0 | 1080 |
| LLPS-Caf-1580 | Canis familiaris | 93.82 | 0.0 | 1069 |
| LLPS-Poa-4605 | Pongo abelii | 93.65 | 0.0 | 1038 |
| LLPS-Chs-3352 | Chlorocebus sabaeus | 93.36 | 0.0 | 1050 |
| LLPS-Cap-1727 | Cavia porcellus | 93.33 | 0.0 | 1067 |
| LLPS-Fud-4090 | Fukomys damarensis | 93.33 | 0.0 | 899 |
| LLPS-Ova-1696 | Ovis aries | 93.23 | 0.0 | 883 |
| LLPS-Man-1023 | Macaca nemestrina | 92.12 | 0.0 | 1069 |
| LLPS-Caj-3264 | Callithrix jacchus | 90.45 | 0.0 | 1071 |
| LLPS-Loa-1496 | Loxodonta africana | 90.22 | 0.0 | 1022 |
| LLPS-Nol-1467 | Nomascus leucogenys | 88.37 | 0.0 | 835 |
| LLPS-Mea-3766 | Mesocricetus auratus | 87.89 | 0.0 | 948 |
| LLPS-Myl-1394 | Myotis lucifugus | 86.48 | 0.0 | 944 |
| LLPS-Sah-2182 | Sarcophilus harrisii | 84.76 | 0.0 | 912 |
| LLPS-Anc-2478 | Anolis carolinensis | 83.79 | 0.0 | 595 |
| LLPS-Ere-0560 | Erinaceus europaeus | 83.18 | 0.0 | 595 |
| LLPS-Pes-1866 | Pelodiscus sinensis | 82.65 | 0.0 | 602 |
| LLPS-Gog-1134 | Gorilla gorilla | 82.65 | 0.0 | 600 |
| LLPS-Ten-3415 | Tetraodon nigroviridis | 80.6 | 0.0 | 581 |
| LLPS-Pof-2941 | Poecilia formosa | 79.57 | 0.0 | 786 |
| LLPS-Orn-3864 | Oreochromis niloticus | 78.96 | 0.0 | 591 |
| LLPS-Cas-4009 | Carlito syrichta | 77.14 | 0.0 | 869 |
| LLPS-Gaa-0403 | Gasterosteus aculeatus | 76.24 | 0.0 | 588 |
| LLPS-Dar-0952 | Danio rerio | 75.9 | 0.0 | 590 |
| LLPS-Asm-2102 | Astyanax mexicanus | 75.82 | 0.0 | 589 |
| LLPS-Cii-0600 | Ciona intestinalis | 74.24 | 2e-175 | 511 |
| LLPS-Leo-1888 | Lepisosteus oculatus | 72.64 | 0.0 | 857 |
| LLPS-Lac-0203 | Latimeria chalumnae | 71.31 | 0.0 | 814 |
| LLPS-Rhb-3507 | Rhinopithecus bieti | 71.13 | 0.0 | 599 |
| LLPS-Xim-2607 | Xiphophorus maculatus | 70.85 | 0.0 | 838 |
| LLPS-Xet-3697 | Xenopus tropicalis | 70.8 | 0.0 | 684 |
| LLPS-Meg-2502 | Meleagris gallopavo | 70.72 | 0.0 | 670 |
| LLPS-Icp-2117 | Ictalurus punctatus | 70.65 | 0.0 | 847 |
| LLPS-Tar-2194 | Takifugu rubripes | 70.44 | 0.0 | 827 |
| LLPS-Tag-3412 | Taeniopygia guttata | 70.23 | 0.0 | 700 |
| LLPS-Gaga-2857 | Gallus gallus | 70.23 | 0.0 | 703 |
| LLPS-Orl-3229 | Oryzias latipes | 69.53 | 0.0 | 821 |
| LLPS-Ict-0973 | Ictidomys tridecemlineatus | 69.47 | 0.0 | 690 |
| LLPS-Scm-3522 | Scophthalmus maximus | 69.29 | 0.0 | 821 |
| LLPS-Anp-2229 | Anas platyrhynchos | 68.91 | 0.0 | 636 |
| LLPS-Fia-3418 | Ficedula albicollis | 68.76 | 0.0 | 559 |
| LLPS-Mod-1446 | Monodelphis domestica | 67.84 | 0.0 | 685 |
| LLPS-Mal-4054 | Mandrillus leucophaeus | 67.33 | 0.0 | 624 |
| LLPS-Tut-1365 | Tursiops truncatus | 67.33 | 0.0 | 625 |
| LLPS-Cae-0220 | Caenorhabditis elegans | 66.58 | 2e-174 | 538 |
| LLPS-Ora-1247 | Ornithorhynchus anatinus | 65.96 | 0.0 | 750 |
| LLPS-Drm-0398 | Drosophila melanogaster | 64.86 | 3e-149 | 457 |
| LLPS-Orc-4371 | Oryctolagus cuniculus | 64.83 | 0.0 | 743 |
| LLPS-Scf-0257 | Scleropages formosus | 64.45 | 0.0 | 733 |
| LLPS-Urm-0247 | Ursus maritimus | 64.44 | 3e-97 | 320 |
| LLPS-Cis-1934 | Ciona savignyi | 58.0 | 1e-141 | 441 |
| LLPS-Brr-2260 | Brassica rapa | 45.74 | 2e-85 | 284 |
| LLPS-Phv-2505 | Phaseolus vulgaris | 45.69 | 5e-85 | 283 |
| LLPS-Bro-2943 | Brassica oleracea | 45.54 | 4e-85 | 283 |
| LLPS-Brn-1105 | Brassica napus | 45.54 | 4e-85 | 283 |
| LLPS-Art-2601 | Arabidopsis thaliana | 44.97 | 4e-87 | 289 |
| LLPS-Arl-1065 | Arabidopsis lyrata | 44.97 | 3e-86 | 286 |
| LLPS-Kop-0972 | Komagataella pastoris | 44.92 | 1e-85 | 286 |
| LLPS-Orm-0713 | Oryza meridionalis | 44.76 | 4e-88 | 291 |
| LLPS-Orbr-0158 | Oryza brachyantha | 44.76 | 1e-87 | 290 |
| LLPS-Sei-0362 | Setaria italica | 44.73 | 2e-86 | 288 |
| LLPS-Zem-1597 | Zea mays | 44.44 | 1e-85 | 291 |
| LLPS-Orr-1376 | Oryza rufipogon | 44.44 | 1e-87 | 290 |
| LLPS-Ors-2364 | Oryza sativa | 44.44 | 1e-87 | 290 |
| LLPS-Lep-2156 | Leersia perrieri | 44.44 | 4e-87 | 289 |
| LLPS-Orgl-0300 | Oryza glumaepatula | 44.44 | 2e-87 | 293 |
| LLPS-Orni-0188 | Oryza nivara | 44.44 | 3e-87 | 292 |
| LLPS-Orb-2279 | Oryza barthii | 44.44 | 2e-87 | 291 |
| LLPS-Sob-2229 | Sorghum bicolor | 43.81 | 8e-85 | 283 |
| LLPS-Sac-0308 | Saccharomyces cerevisiae | 43.03 | 2e-86 | 290 |
| LLPS-Nia-2028 | Nicotiana attenuata | 41.62 | 2e-85 | 284 |