LLPS-Ova-1696
MARK4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Non-specific serine/threonine protein kinase |
| Gene Name: | MARK4 |
| Ensembl Gene: | ENSOARG00000009757.1 |
| Ensembl Protein: | ENSOARP00000010463.1 |
| Organism: | Ovis aries |
| Taxa ID: | 9940 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOART00000010618.1 | ENSOARP00000010463.1 |
| UniProt | W5PJ43, W5PJ43_SHEEP | |
| GeneBank | AMGL01029136, AMGL01029137 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 LAGRTGAARH SRSVSPPQHG TLGSGRSSDK GPSWSSRSLG ARCRNSIASC PEEQPHVGNY 60 61 RLLRTIGKGN FAKVKLARHI LTGREVAIKI IDKTQLNPSS LQKLFREVRI MKGLNHPNIV 120 121 KLFEVIETEK TLYLVMEYAS AGEVFDYLVS HGRMKEKEAR AKFRQIVSAV HYCHQKNIVH 180 181 RDLKAENLLL DAEANIKIAD FGFSNEFTLG SKLDTFCGSP PYAAPELRKS RADAVPSSDP 240 241 WPAAGMLRPA QSGRLEQSGD RMGEELRERV LRGKYRVPFY MSTDCESILR RFLVLNPAKR 300 301 CTLEQIMKDK WINIGYEGEE LKPYTEPEED FGDTKRIEVM VGMGYTREEI KEALTSQKYN 360 361 EVTATYLLLG RKTEEGGDRG APGLALARVR APSDTTNGTS SSKGTSHSKG QRSSSSTYHR 420 421 QRRHSDFCGP SPTPLHPKRS PTSTGEAELK EERLPGRKAS CSAAGSGSRG LPPSSPMVSS 480 481 AHNPNKAEIP ERRKDSTSTP NNLPPSMMTR RNTYVCTERP GAERPSLLPN GKENSHQHQQ 540 541 SSLPPSLPTS LGNLSSFFLN DPFLELERSP RMSQLQHPLV GGISNLLAKF GESSGTPRVP 600 601 PAPRPPPPEP PPLPPGRPRP TTNLFTKLTS KLTRRVTDEP ERIGGPEVTS CHLPWDQTET 660 661 APRLLRFPWS VKLTSSRPPE ALMAALLQAT AAARCRCRQP QPFLLACLHG GAGGPEPLSH 720 721 FEVEVCQLPR PGLRGVLFRR VAGTALAFRT LVTRISNDLE L 761 |
| Nucleotide CDS Sequence (FASTA) |
1 CTGGCGGGTC GGACGGGCGC TGCCCGCCAC TCACGCTCCG TCTCCCCCCC TCAGCATGGC 60 61 ACCCTGGGCA GTGGCCGCTC CTCAGACAAG GGCCCATCCT GGTCCAGCCG CTCCCTGGGC 120 121 GCCCGCTGCC GGAACTCCAT CGCCTCCTGT CCCGAGGAGC AGCCCCACGT AGGCAACTAC 180 181 CGCCTGCTGA GGACCATCGG GAAAGGCAAC TTTGCCAAAG TCAAGCTGGC CCGCCACATC 240 241 CTTACTGGCC GGGAGGTCGC CATCAAGATC ATCGACAAAA CCCAGCTGAA CCCCAGCAGC 300 301 CTGCAAAAGC TGTTCCGAGA AGTCCGTATC ATGAAGGGCC TAAACCACCC CAACATCGTG 360 361 AAGCTCTTCG AGGTGATTGA GACGGAGAAG ACGCTGTACC TGGTGATGGA ATATGCAAGT 420 421 GCTGGAGAAG TGTTTGACTA CCTCGTGTCG CACGGCCGCA TGAAGGAGAA GGAGGCTCGA 480 481 GCCAAGTTCC GACAGATTGT GTCGGCCGTG CACTACTGTC ACCAGAAAAA TATTGTCCAC 540 541 AGGGACCTGA AGGCCGAGAA CCTCCTGCTG GACGCCGAGG CCAACATCAA GATCGCCGAC 600 601 TTTGGCTTCA GCAATGAGTT CACGCTGGGC TCGAAGCTGG ACACCTTTTG CGGGAGCCCC 660 661 CCGTACGCCG CCCCGGAGCT GAGGAAGTCC AGAGCGGATG CAGTCCCCAG CTCTGACCCA 720 721 TGGCCCGCGG CAGGAATGCT CAGGCCTGCT CAAAGTGGCC GTTTGGAGCA GTCAGGGGAT 780 781 CGGATGGGAG AAGAGCTGCG GGAGCGAGTC CTCAGAGGGA AGTACCGGGT CCCTTTCTAC 840 841 ATGTCAACAG ACTGTGAGAG CATCCTGCGG AGATTTTTGG TGCTGAACCC AGCTAAACGC 900 901 TGTACTCTCG AGCAAATCAT GAAAGACAAA TGGATCAACA TCGGCTATGA GGGTGAGGAG 960 961 TTGAAGCCAT ACACAGAGCC CGAGGAGGAC TTCGGGGACA CCAAGCGAAT CGAGGTGATG 1020 1021 GTGGGTATGG GCTACACGCG GGAAGAAATC AAAGAGGCCT TGACCAGCCA GAAGTACAAC 1080 1081 GAAGTGACTG CCACCTACCT CCTGCTGGGC AGGAAGACTG AGGAGGGTGG GGACCGGGGT 1140 1141 GCCCCGGGGC TGGCCTTGGC ACGGGTGCGG GCGCCCAGCG ACACCACCAA TGGAACAAGC 1200 1201 TCCAGCAAAG GCACCAGCCA CAGCAAAGGG CAGCGGAGTT CCTCCTCCAC CTACCACCGC 1260 1261 CAGCGCAGGC ATAGCGACTT CTGTGGCCCG TCCCCCACAC CCCTGCACCC CAAGCGCAGC 1320 1321 CCAACCAGCA CGGGGGAGGC GGAGCTGAAG GAGGAGCGCC TGCCAGGCCG GAAGGCGAGC 1380 1381 TGCAGTGCTG CGGGCAGCGG GAGCCGAGGG CTGCCCCCCT CCAGCCCCAT GGTCAGCAGC 1440 1441 GCCCACAACC CCAACAAGGC AGAGATCCCA GAGCGGCGGA AGGACAGCAC GAGCACCCCT 1500 1501 AACAACCTCC CTCCCAGCAT GATGACCCGC AGAAACACCT ACGTTTGCAC AGAACGCCCG 1560 1561 GGGGCTGAGC GCCCATCCTT GTTGCCAAAT GGCAAAGAAA ACAGTCATCA GCACCAGCAA 1620 1621 AGCAGTCTGC CCCCCTCTCT GCCCACGAGC CTGGGGAACC TGAGTTCATT TTTTTTGAAT 1680 1681 GATCCATTTT TAGAGTTGGA GAGAAGCCCT AGAATGTCAC AGCTTCAACA TCCTCTAGTT 1740 1741 GGCGGGATTT CAAACTTGCT TGCCAAGTTT GGAGAGAGCT CGGGTACCCC ACGGGTGCCC 1800 1801 CCCGCCCCCC GCCCACCGCC CCCCGAACCC CCGCCCCTGC CCCCTGGGCG GCCCCGCCCC 1860 1861 ACCACCAACC TCTTCACCAA GCTGACCTCC AAACTGACCC GAAGGGTCAC AGACGAACCT 1920 1921 GAGAGAATCG GGGGACCTGA GGTCACAAGT TGCCATCTAC CTTGGGATCA AACGGAAACC 1980 1981 GCCCCCCGGT TGCTCCGATT CCCCTGGAGT GTGAAACTGA CCAGCTCACG CCCACCCGAG 2040 2041 GCCCTGATGG CAGCTCTGCT CCAGGCCACA GCGGCCGCCC GCTGCCGCTG CCGCCAGCCA 2100 2101 CAGCCGTTCC TGCTGGCCTG CCTGCACGGG GGTGCGGGCG GGCCCGAGCC CCTGTCCCAC 2160 2161 TTCGAAGTGG AGGTCTGCCA GCTGCCCCGG CCGGGCCTGC GGGGAGTTCT CTTCCGCCGC 2220 2221 GTGGCGGGCA CTGCCCTGGC CTTCCGCACC CTCGTCACCC GCATCTCCAA CGACCTCGAG 2280 2281 CTCTGA 2286 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Aim-3618 | Ailuropoda melanoleuca | 92.86 | 7e-47 | 182 |
| LLPS-Myl-1394 | Myotis lucifugus | 91.38 | 0.0 | 831 |
| LLPS-Cas-4009 | Carlito syrichta | 91.3 | 9e-24 | 110 |
| LLPS-Fud-4090 | Fukomys damarensis | 89.38 | 0.0 | 834 |
| LLPS-Bot-2437 | Bos taurus | 87.66 | 0.0 | 1162 |
| LLPS-Sus-3404 | Sus scrofa | 87.5 | 0.0 | 1132 |
| LLPS-Cea-2813 | Cercocebus atys | 87.37 | 0.0 | 1129 |
| LLPS-Aon-3096 | Aotus nancymaae | 87.37 | 0.0 | 1129 |
| LLPS-Maf-0103 | Macaca fascicularis | 87.37 | 0.0 | 1130 |
| LLPS-Paa-0834 | Papio anubis | 87.37 | 0.0 | 1130 |
| LLPS-Pap-4698 | Pan paniscus | 87.23 | 0.0 | 1129 |
| LLPS-Pat-3865 | Pan troglodytes | 87.23 | 0.0 | 1129 |
| LLPS-Mam-4391 | Macaca mulatta | 87.23 | 0.0 | 1129 |
| LLPS-Hos-2414 | Homo sapiens | 87.1 | 0.0 | 1129 |
| LLPS-Otg-3161 | Otolemur garnettii | 86.83 | 0.0 | 1122 |
| LLPS-Fec-0779 | Felis catus | 86.69 | 0.0 | 1124 |
| LLPS-Eqc-3133 | Equus caballus | 86.61 | 0.0 | 1122 |
| LLPS-Mum-3604 | Mus musculus | 86.16 | 0.0 | 1123 |
| LLPS-Ran-3079 | Rattus norvegicus | 86.16 | 0.0 | 1119 |
| LLPS-Poa-4605 | Pongo abelii | 86.14 | 0.0 | 1118 |
| LLPS-Caf-1580 | Canis familiaris | 85.75 | 0.0 | 1124 |
| LLPS-Cap-1727 | Cavia porcellus | 85.6 | 0.0 | 1116 |
| LLPS-Chs-3352 | Chlorocebus sabaeus | 84.99 | 0.0 | 1092 |
| LLPS-Mup-3382 | Mustela putorius furo | 84.0 | 0.0 | 902 |
| LLPS-Man-1023 | Macaca nemestrina | 83.95 | 0.0 | 1118 |
| LLPS-Sah-2182 | Sarcophilus harrisii | 83.91 | 0.0 | 785 |
| LLPS-Caj-3264 | Callithrix jacchus | 83.87 | 0.0 | 1113 |
| LLPS-Loa-1496 | Loxodonta africana | 83.47 | 0.0 | 1070 |
| LLPS-Dio-3478 | Dipodomys ordii | 82.52 | 0.0 | 919 |
| LLPS-Nol-1467 | Nomascus leucogenys | 80.18 | 0.0 | 876 |
| LLPS-Mea-3766 | Mesocricetus auratus | 79.17 | 0.0 | 984 |
| LLPS-Anc-2478 | Anolis carolinensis | 75.3 | 5e-171 | 521 |
| LLPS-Ere-0560 | Erinaceus europaeus | 74.85 | 8e-177 | 523 |
| LLPS-Gog-1134 | Gorilla gorilla | 74.49 | 4e-174 | 527 |
| LLPS-Pof-2941 | Poecilia formosa | 74.12 | 0.0 | 717 |
| LLPS-Orn-1882 | Oreochromis niloticus | 73.3 | 0.0 | 726 |
| LLPS-Dar-3056 | Danio rerio | 73.28 | 0.0 | 731 |
| LLPS-Leo-1888 | Lepisosteus oculatus | 72.66 | 0.0 | 726 |
| LLPS-Gaa-0756 | Gasterosteus aculeatus | 72.19 | 0.0 | 714 |
| LLPS-Asm-2647 | Astyanax mexicanus | 71.43 | 0.0 | 709 |
| LLPS-Ten-0184 | Tetraodon nigroviridis | 71.04 | 0.0 | 686 |
| LLPS-Icp-2117 | Ictalurus punctatus | 70.94 | 0.0 | 714 |
| LLPS-Lac-0203 | Latimeria chalumnae | 70.94 | 0.0 | 684 |
| LLPS-Tar-2194 | Takifugu rubripes | 70.27 | 0.0 | 703 |
| LLPS-Scm-3522 | Scophthalmus maximus | 70.13 | 0.0 | 711 |
| LLPS-Xim-2607 | Xiphophorus maculatus | 69.94 | 0.0 | 706 |
| LLPS-Orl-3229 | Oryzias latipes | 69.0 | 0.0 | 684 |
| LLPS-Urm-2924 | Ursus maritimus | 67.65 | 2e-175 | 530 |
| LLPS-Xet-3697 | Xenopus tropicalis | 65.73 | 0.0 | 612 |
| LLPS-Rhb-3507 | Rhinopithecus bieti | 65.34 | 4e-175 | 530 |
| LLPS-Meg-2502 | Meleagris gallopavo | 65.27 | 0.0 | 609 |
| LLPS-Ora-1247 | Ornithorhynchus anatinus | 65.25 | 0.0 | 635 |
| LLPS-Tag-3412 | Taeniopygia guttata | 65.06 | 0.0 | 632 |
| LLPS-Gaga-2857 | Gallus gallus | 65.06 | 0.0 | 636 |
| LLPS-Cii-0600 | Ciona intestinalis | 65.0 | 1e-147 | 442 |
| LLPS-Pes-1866 | Pelodiscus sinensis | 64.94 | 2e-175 | 529 |
| LLPS-Scf-0257 | Scleropages formosus | 64.67 | 0.0 | 618 |
| LLPS-Ict-0973 | Ictidomys tridecemlineatus | 64.29 | 0.0 | 622 |
| LLPS-Orc-4371 | Oryctolagus cuniculus | 64.09 | 0.0 | 627 |
| LLPS-Anp-2229 | Anas platyrhynchos | 63.69 | 0.0 | 558 |
| LLPS-Mod-1446 | Monodelphis domestica | 62.8 | 0.0 | 617 |
| LLPS-Fia-3418 | Ficedula albicollis | 62.12 | 2e-161 | 491 |
| LLPS-Tut-1365 | Tursiops truncatus | 62.1 | 0.0 | 550 |
| LLPS-Mal-4054 | Mandrillus leucophaeus | 61.71 | 0.0 | 548 |
| LLPS-Cae-0220 | Caenorhabditis elegans | 60.99 | 2e-144 | 461 |
| LLPS-Drm-0398 | Drosophila melanogaster | 58.92 | 3e-126 | 400 |
| LLPS-Cis-1457 | Ciona savignyi | 45.79 | 6e-73 | 252 |
| LLPS-Yal-0727 | Yarrowia lipolytica | 41.61 | 8e-68 | 240 |
| LLPS-Kop-0972 | Komagataella pastoris | 41.41 | 7e-71 | 248 |
| LLPS-Brr-2260 | Brassica rapa | 40.88 | 2e-67 | 237 |
| LLPS-Phv-2505 | Phaseolus vulgaris | 40.76 | 1e-67 | 238 |
| LLPS-Brn-1105 | Brassica napus | 40.63 | 2e-67 | 237 |
| LLPS-Bro-2943 | Brassica oleracea | 40.63 | 2e-67 | 237 |
| LLPS-Arl-1065 | Arabidopsis lyrata | 40.13 | 2e-68 | 240 |
| LLPS-Art-2601 | Arabidopsis thaliana | 40.13 | 4e-69 | 242 |
| LLPS-Sei-0362 | Setaria italica | 40.06 | 1e-68 | 241 |
| LLPS-Orbr-0158 | Oryza brachyantha | 39.87 | 7e-70 | 244 |
| LLPS-Orm-0713 | Oryza meridionalis | 39.87 | 2e-70 | 246 |
| LLPS-Sac-0308 | Saccharomyces cerevisiae | 39.64 | 2e-70 | 249 |
| LLPS-Orb-2279 | Oryza barthii | 39.56 | 9e-70 | 244 |
| LLPS-Orni-0188 | Oryza nivara | 39.56 | 2e-69 | 246 |
| LLPS-Lep-2156 | Leersia perrieri | 39.56 | 2e-69 | 243 |
| LLPS-Orgl-0300 | Oryza glumaepatula | 39.56 | 2e-69 | 246 |
| LLPS-Ors-2364 | Oryza sativa | 39.56 | 7e-70 | 244 |
| LLPS-Orr-1376 | Oryza rufipogon | 39.56 | 7e-70 | 244 |
| LLPS-Zem-1597 | Zea mays | 39.56 | 8e-68 | 244 |
| LLPS-Sol-1999 | Solanum lycopersicum | 38.02 | 3e-67 | 237 |
| LLPS-Nia-2028 | Nicotiana attenuata | 37.18 | 1e-67 | 238 |