• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sob-0362
SORBI_3009G050700

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Importin subunit alpha
Gene Name: SORBI_3009G050700
Ensembl Gene: SORBI_3009G050700
Ensembl Protein: EES19061
Organism: Sorghum bicolor
Taxa ID: 4558
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEES19061EES19061
UniProtC5Z0J7, C5Z0J7_SORBI
GeneBankCM000768EES19061.1
RefSeqXM_002440586.1XP_002440631.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSLRPSEREQ  MRKGNYKQTV  DAEESRRRRE  GQMVDIRKAK  REESLQKKRR  DGFPASAAGA  60
61    VPPMGHSTAL  QQKLDGLPAM  VQAVLSNDPT  VQLDATTQFR  KLLSIERSPP  IEEVISTGVV  120
121   PRFIEFLTRE  DHPQLQFEAA  WALTNIASGT  SENTKVVVES  GAVPIFVKLL  NSHSEDVREQ  180
181   AVWALGNVAG  DSPKCRDLVL  GHGGLFPLLQ  QLNEHAKLSM  LRNATWTLSN  FCRGKPQPNF  240
241   DQVKPALPAL  QRLIHSQDEE  VLTDACWALS  YLSDGTNDKI  QAVIESGVFP  RLVELLMHPS  300
301   ASVLIPALRT  VGNIVTGDDM  QTQCVIDNQA  LPCLLNLLTT  NHKKSIKKEA  CWTISNITAG  360
361   NREQIQAVIN  ANIIAPLVQL  LQTAEFDIKK  EAAWAISNAT  SGGTHDQIKY  LVAQGCIKPL  420
421   CDLLVCPDPR  IVTVCLEGLE  NILKVGEAEK  NLGGGDVNVY  AQMIDDAEGL  DKIENLQSHD  480
481   NTEIYEKAVK  MLESYWLEEE  DDAMPSGDNP  QNGFNFGNQP  SVPSGGFNFG  530
Nucleotide CDS Sequence (FASTA)
1     ATGTCGCTCC  GGCCGAGCGA  GCGGGAGCAG  ATGCGGAAGG  GCAACTACAA  GCAGACGGTG  60
61    GACGCGGAGG  AGAGCCGCCG  CCGCCGGGAG  GGCCAGATGG  TGGACATCCG  CAAGGCCAAG  120
121   CGCGAGGAGA  GCCTCCAGAA  GAAGCGCCGC  GACGGCTTCC  CGGCCTCCGC  CGCCGGCGCC  180
181   GTCCCGCCCA  TGGGACACTC  CACCGCGCTC  CAGCAGAAGC  TCGATGGCTT  GCCCGCTATG  240
241   GTGCAGGCCG  TCCTCTCCAA  CGACCCCACC  GTGCAGCTTG  ACGCCACCAC  GCAGTTCAGG  300
301   AAGCTGCTCT  CCATAGAGCG  TAGTCCCCCA  ATTGAGGAGG  TGATCAGCAC  AGGAGTGGTC  360
361   CCTCGATTCA  TCGAGTTCCT  TACACGCGAG  GACCATCCCC  AACTCCAGTT  TGAGGCTGCG  420
421   TGGGCACTCA  CCAACATTGC  CTCCGGCACA  TCAGAGAATA  CCAAGGTGGT  GGTTGAGAGT  480
481   GGTGCTGTGC  CCATCTTTGT  CAAGCTCCTC  AACTCCCACA  GCGAGGATGT  TCGTGAACAG  540
541   GCTGTGTGGG  CTTTAGGTAA  TGTTGCTGGT  GACTCCCCAA  AGTGCCGTGA  TCTGGTGCTT  600
601   GGTCATGGTG  GGCTTTTCCC  CTTGCTGCAG  CAGCTTAATG  AGCATGCTAA  GCTCTCGATG  660
661   CTCAGGAATG  CCACATGGAC  TCTCTCCAAC  TTTTGCCGTG  GGAAGCCACA  ACCAAACTTT  720
721   GATCAGGTCA  AACCAGCATT  GCCAGCACTG  CAGCGCCTTA  TCCACTCTCA  GGATGAGGAG  780
781   GTCCTAACTG  ATGCCTGCTG  GGCTCTCTCA  TACCTATCTG  ATGGGACTAA  TGACAAAATC  840
841   CAAGCTGTCA  TTGAATCTGG  CGTGTTCCCA  CGCCTTGTGG  AACTTCTGAT  GCATCCTTCG  900
901   GCCTCTGTAC  TCATTCCTGC  TCTGCGCACG  GTGGGTAACA  TTGTAACTGG  GGATGACATG  960
961   CAGACTCAGT  GTGTCATTGA  CAATCAAGCA  CTTCCATGCC  TTTTGAACCT  CCTGACTACC  1020
1021  AACCACAAGA  AAAGCATCAA  GAAAGAAGCA  TGCTGGACAA  TCTCAAACAT  CACAGCTGGT  1080
1081  AACAGGGAAC  AAATTCAGGC  CGTGATCAAT  GCAAACATAA  TTGCACCTCT  GGTGCAACTT  1140
1141  CTGCAAACTG  CTGAATTTGA  CATCAAGAAA  GAAGCAGCCT  GGGCAATTTC  AAATGCCACT  1200
1201  TCTGGGGGCA  CACATGATCA  GATCAAGTAC  CTTGTTGCCC  AGGGGTGCAT  TAAGCCACTC  1260
1261  TGTGACCTGC  TTGTCTGCCC  AGATCCTAGA  ATTGTAACAG  TTTGCTTGGA  GGGTCTTGAG  1320
1321  AACATCCTGA  AGGTTGGCGA  GGCAGAGAAA  AACCTTGGTG  GAGGCGATGT  CAATGTCTAT  1380
1381  GCACAGATGA  TTGATGATGC  TGAGGGCCTT  GACAAGATCG  AGAACCTGCA  GAGCCATGAC  1440
1441  AACACTGAGA  TATATGAGAA  GGCTGTCAAG  ATGCTCGAAT  CCTACTGGCT  GGAGGAGGAA  1500
1501  GATGATGCCA  TGCCCTCAGG  CGACAATCCC  CAGAATGGCT  TCAACTTTGG  GAACCAGCCC  1560
1561  TCTGTTCCAT  CAGGTGGATT  CAACTTTGGC  TGA  1593

▼ KEYWORD

ID
Family
Complete proteome
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Molecular Function
Nuclear import signal receptor activity
Molecular Function
Protein transporter activity
Biological Process
Protein import into nucleus

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Zem-0534Zea mays98.680.01051
LLPS-Sei-0627Setaria italica96.420.01033
LLPS-Ori-0779Oryza indica91.630.0 908
LLPS-Lep-1207Leersia perrieri90.210.0 949
LLPS-Ors-1730Oryza sativa89.890.0 951
LLPS-Orm-0572Oryza meridionalis89.890.0 951
LLPS-Org-0778Oryza glaberrima89.890.0 951
LLPS-Orb-0437Oryza barthii89.560.0 933
LLPS-Orgl-1316Oryza glumaepatula89.560.0 933
LLPS-Brd-2377Brachypodium distachyon89.470.0 956
LLPS-Orbr-0801Oryza brachyantha89.450.0 932
LLPS-Orr-0629Oryza rufipogon89.060.0 933
LLPS-Orp-1406Oryza punctata89.020.0 924
LLPS-Tra-0265Triticum aestivum88.950.0 947
LLPS-Hov-1230Hordeum vulgare88.950.0 944
LLPS-Orni-2330Oryza nivara86.920.0 923
LLPS-Mae-0864Manihot esculenta82.140.0 872
LLPS-Mua-1560Musa acuminata81.840.0 875
LLPS-Coc-1121Corchorus capsularis81.320.0 858
LLPS-Pot-2346Populus trichocarpa80.410.0 853
LLPS-Via-2184Vigna angularis80.340.0 855
LLPS-Glm-1741Glycine max79.780.0 850
LLPS-Cus-0336Cucumis sativus79.70.0 848
LLPS-Vir-0910Vigna radiata79.430.0 843
LLPS-Phv-2356Phaseolus vulgaris79.40.0 847
LLPS-Amt-1823Amborella trichopoda79.360.0 837
LLPS-Met-1230Medicago truncatula79.210.0 844
LLPS-Sot-1448Solanum tuberosum79.10.0 839
LLPS-Tru-1091Triticum urartu79.040.0 815
LLPS-Prp-0443Prunus persica78.720.0 837
LLPS-Sol-0417Solanum lycopersicum78.530.0 834
LLPS-Thc-1002Theobroma cacao78.420.0 831
LLPS-Hea-1740Helianthus annuus78.090.0 814
LLPS-Gor-1489Gossypium raimondii77.740.0 829
LLPS-Art-1775Arabidopsis thaliana77.530.0 813
LLPS-Viv-0825Vitis vinifera77.260.0 825
LLPS-Arl-1579Arabidopsis lyrata76.850.0 823
LLPS-Nia-2368Nicotiana attenuata76.680.0 816
LLPS-Brr-2756Brassica rapa75.890.0 797
LLPS-Brn-3381Brassica napus75.610.0 798
LLPS-Php-0139Physcomitrella patens75.560.0 792
LLPS-Bro-2775Brassica oleracea75.050.0 791
LLPS-Sem-1193Selaginella moellendorffii71.990.0 761
LLPS-Dac-2249Daucus carota69.720.0 793
LLPS-Chr-1314Chlamydomonas reinhardtii65.610.0 672
LLPS-Osl-0501Ostreococcus lucimarinus65.230.0 650
LLPS-Gas-0099Galdieria sulphuraria63.910.0 640
LLPS-Asni-0590Aspergillus niger62.334e-174 507
LLPS-Aon-2404Aotus nancymaae61.890.0 525
LLPS-Phn-1333Phaeosphaeria nodorum61.867e-177 514
LLPS-Chc-0767Chondrus crispus61.390.0 639
LLPS-Fia-0569Ficedula albicollis61.377e-177 513
LLPS-Mel-0289Melampsora laricipopulina61.210.0 580
LLPS-Asm-1163Astyanax mexicanus61.016e-178 521
LLPS-Mao-1285Magnaporthe oryzae60.510.0 556
LLPS-Fus-1103Fusarium solani60.350.0 561
LLPS-Fuv-1029Fusarium verticillioides60.080.0 559
LLPS-Fuo-0668Fusarium oxysporum60.080.0 559
LLPS-Lem-0538Leptosphaeria maculans60.00.0 551
LLPS-Beb-0176Beauveria bassiana59.810.0 554
LLPS-Nec-0625Neurospora crassa59.670.0 567
LLPS-Pug-0310Puccinia graminis59.470.0 561
LLPS-Ved-1391Verticillium dahliae59.450.0 543
LLPS-Coo-1424Colletotrichum orbiculare59.40.0 558
LLPS-Cogr-0059Colletotrichum graminicola59.40.0 561
LLPS-Nef-0967Neosartorya fischeri59.390.0 556
LLPS-Asfu-0373Aspergillus fumigatus59.390.0 557
LLPS-Blg-0677Blumeria graminis59.380.0 540
LLPS-Dos-0786Dothistroma septosporum59.310.0 549
LLPS-Aso-0120Aspergillus oryzae59.280.0 558
LLPS-Asf-0705Aspergillus flavus59.280.0 558
LLPS-Zyt-0523Zymoseptoria tritici59.230.0 553
LLPS-Chs-0532Chlorocebus sabaeus59.121e-174 511
LLPS-Maf-1483Macaca fascicularis59.121e-174 511
LLPS-Cea-1352Cercocebus atys59.124e-174 511
LLPS-Mal-0958Mandrillus leucophaeus59.121e-174 511
LLPS-Man-2885Macaca nemestrina59.121e-174 511
LLPS-Mam-3200Macaca mulatta59.121e-174 511
LLPS-Cog-0318Colletotrichum gloeosporioides59.110.0 557
LLPS-Cas-1312Carlito syrichta59.085e-179 522
LLPS-Trv-1149Trichoderma virens59.070.0 572
LLPS-Asc-0429Aspergillus clavatus59.010.0 557
LLPS-Paa-0703Papio anubis58.952e-177 518
LLPS-Urm-1804Ursus maritimus58.927e-173 506
LLPS-Sus-1515Sus scrofa58.912e-174 510
LLPS-Gog-0449Gorilla gorilla58.912e-174 511
LLPS-Aim-2129Ailuropoda melanoleuca58.913e-174 510
LLPS-Pat-3837Pan troglodytes58.912e-174 511
LLPS-Hos-2834Homo sapiens58.914e-174 510
LLPS-Orc-2553Oryctolagus cuniculus58.919e-174 509
LLPS-Gaga-0927Gallus gallus58.792e-175 521
LLPS-Anp-2248Anas platyrhynchos58.754e-179 523
LLPS-Tag-0575Taeniopygia guttata58.755e-179 522
LLPS-Caj-0851Callithrix jacchus58.78e-174 509
LLPS-Bot-3694Bos taurus58.78e-175 511
LLPS-Ova-0586Ovis aries58.76e-175 512
LLPS-Fec-2528Felis catus58.73e-174 510
LLPS-Otg-4390Otolemur garnettii58.71e-173 509
LLPS-Eqc-3148Equus caballus58.74e-178 520
LLPS-Trr-0178Trichoderma reesei58.670.0 569
LLPS-Scm-3715Scophthalmus maximus58.51e-179 524
LLPS-Asn-0636Aspergillus nidulans58.490.0 558
LLPS-Pyt-0403Pyrenophora teres58.380.0 555
LLPS-Miv-0546Microbotryum violaceum58.370.0 540
LLPS-Leo-0867Lepisosteus oculatus58.331e-177 519
LLPS-Orl-0830Oryzias latipes58.32e-174 510
LLPS-Pytr-0295Pyrenophora triticirepentis58.190.0 545
LLPS-Tut-1224Tursiops truncatus58.166e-171 503
LLPS-Ast-0980Aspergillus terreus58.150.0 554
LLPS-Dar-4244Danio rerio58.130.0 531
LLPS-Caf-2487Canis familiaris58.132e-170 500
LLPS-Xet-0948Xenopus tropicalis58.130.0 535
LLPS-Anc-2101Anolis carolinensis58.12e-176 516
LLPS-Meg-1227Meleagris gallopavo58.050.0 536
LLPS-Tar-2551Takifugu rubripes58.024e-178 520
LLPS-Xim-2775Xiphophorus maculatus58.021e-173 508
LLPS-Ten-1239Tetraodon nigroviridis58.027e-179 522
LLPS-Gaa-3659Gasterosteus aculeatus57.913e-176 515
LLPS-Pap-1025Pan paniscus57.871e-177 519
LLPS-Mum-4601Mus musculus57.850.0 534
LLPS-Dio-0622Dipodomys ordii57.850.0 530
LLPS-Ran-2079Rattus norvegicus57.850.0 535
LLPS-Ict-3964Ictidomys tridecemlineatus57.850.0 533
LLPS-Crn-0453Cryptococcus neoformans57.760.0 553
LLPS-Gag-1206Gaeumannomyces graminis57.750.0 565
LLPS-Pes-3493Pelodiscus sinensis57.743e-179 524
LLPS-Sah-1405Sarcophilus harrisii57.719e-178 519
LLPS-Pof-1605Poecilia formosa57.688e-172 504
LLPS-Fud-4196Fukomys damarensis57.650.0 531
LLPS-Cap-1657Cavia porcellus57.650.0 533
LLPS-Map-0249Magnaporthe poae57.560.0 563
LLPS-Myl-2774Myotis lucifugus57.460.0 530
LLPS-Mod-1939Monodelphis domestica57.462e-178 521
LLPS-Ora-3345Ornithorhynchus anatinus57.45e-173 507
LLPS-Scf-1576Scleropages formosus57.280.0 530
LLPS-Spr-0381Sporisorium reilianum57.170.0 543
LLPS-Orn-2860Oreochromis niloticus57.143e-180 525
LLPS-Usm-0637Ustilago maydis57.140.0 541
LLPS-Tum-0208Tuber melanosporum57.010.0 549
LLPS-Abg-1931Absidia glauca57.00.0 541
LLPS-Loa-1637Loxodonta africana56.981e-180 526
LLPS-Icp-3541Ictalurus punctatus56.942e-173 508
LLPS-Yal-0529Yarrowia lipolytica56.930.0 542
LLPS-Put-0181Puccinia triticina56.064e-174 510
LLPS-Mea-3609Mesocricetus auratus55.182e-170 500
LLPS-Asg-1455Ashbya gossypii54.391e-171 503
LLPS-Lac-2517Latimeria chalumnae54.343e-173 507
LLPS-Scj-0572Schizosaccharomyces japonicus54.173e-178 521
LLPS-Scc-1227Schizosaccharomyces cryophilus54.144e-175 512
LLPS-Scp-1166Schizosaccharomyces pombe53.41e-174 511