• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sah-2199
EEF1A2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Elongation factor 1-alpha
Gene Name: EEF1A2
Ensembl Gene: ENSSHAG00000018414.1
Ensembl Protein: ENSSHAP00000021747.1
Organism: Sarcophilus harrisii
Taxa ID: 9305
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGKEKTHINI  VVIGHVDSGK  STTTGHLIYK  CGGIDKRTIE  KFEKEAAEMG  KGSFKYAWVL  60
61    DKLKAERERG  ITIDISLWKF  ETTKYYITII  DAPGHRDFIK  NMITGTSQAD  CAVLIVAAGV  120
121   GEFEAGISKN  GQTREHALLA  YTLGVKQLIV  GINKMDSTEP  PYSEKRYDEI  VKEVSAYIKK  180
181   IGYNPATVPF  VPISGWHGDN  MLEPSPNMPW  FKGWKVERKE  GNASGVSLLE  ALDTILPPTR  240
241   PTDKPLRLPL  QDVYKIGGIG  TVPVGRVETG  ILRPGMVVTF  APVNITTEVK  SVEMHHEALS  300
301   EALPGDNVGF  NVKNVSVKDI  RRGNVCGDSK  SDPPQEAAQF  TSQVIILNHP  GQISAGYSPV  360
361   IDCHTAHIAC  KFAELKEKID  RRSGKKLEDN  PKSLKSGDAA  IVEMIPGKPM  CVESFSQYPP  420
421   LGRFAVRDMR  QTVAVGVIKN  VEKKSGGAGK  VTKSAQKAQK  AGK  463
Nucleotide CDS Sequence (FASTA)
1     ATGGGTAAGG  AGAAGACCCA  CATCAATATC  GTTGTCATTG  GCCATGTAGA  TTCAGGCAAG  60
61    TCCACTACCA  CAGGGCACCT  CATATACAAG  TGTGGGGGCA  TTGACAAGCG  GACCATTGAA  120
121   AAGTTTGAGA  AGGAAGCTGC  AGAGATGGGG  AAAGGCTCCT  TTAAGTATGC  TTGGGTCCTG  180
181   GATAAGCTCA  AGGCTGAGCG  TGAGCGGGGG  ATCACCATTG  ATATCTCTCT  CTGGAAGTTT  240
241   GAGACGACCA  AATATTACAT  CACCATCATT  GATGCACCAG  GACACAGAGA  TTTTATCAAG  300
301   AACATGATCA  CAGGAACTTC  TCAGGCTGAT  TGCGCAGTGC  TGATTGTGGC  TGCAGGGGTG  360
361   GGAGAGTTTG  AAGCTGGCAT  CTCCAAAAAT  GGGCAGACCC  GGGAGCATGC  CTTGCTGGCT  420
421   TACACTCTGG  GTGTGAAACA  GCTTATTGTG  GGGATCAACA  AGATGGACTC  CACAGAGCCC  480
481   CCCTACAGCG  AAAAGCGCTA  TGATGAAATC  GTCAAGGAGG  TCAGCGCCTA  CATCAAGAAG  540
541   ATTGGCTACA  ACCCTGCCAC  AGTCCCCTTT  GTGCCCATTT  CAGGTTGGCA  TGGTGACAAC  600
601   ATGTTGGAGC  CATCCCCAAA  TATGCCTTGG  TTTAAGGGTT  GGAAGGTGGA  GCGTAAGGAA  660
661   GGAAATGCCA  GTGGTGTATC  CCTGCTGGAA  GCCTTGGATA  CTATCCTGCC  CCCCACCCGC  720
721   CCAACAGACA  AACCCTTGCG  CCTCCCACTT  CAGGATGTCT  ACAAGATTGG  AGGTATTGGA  780
781   ACAGTGCCTG  TGGGCCGAGT  GGAGACAGGG  ATCCTTCGGC  CAGGAATGGT  GGTAACCTTT  840
841   GCTCCTGTAA  ACATCACCAC  TGAGGTGAAG  TCAGTGGAGA  TGCACCATGA  GGCCCTGAGT  900
901   GAGGCCCTTC  CTGGAGACAA  CGTAGGATTC  AATGTGAAAA  ACGTGTCTGT  CAAGGACATC  960
961   CGCCGTGGCA  ATGTCTGTGG  TGACAGCAAG  TCAGACCCTC  CCCAGGAGGC  TGCTCAATTC  1020
1021  ACCTCCCAGG  TCATCATCCT  GAACCACCCA  GGGCAGATCA  GTGCCGGCTA  CTCGCCTGTC  1080
1081  ATTGATTGCC  ACACTGCCCA  CATTGCCTGC  AAGTTTGCTG  AGCTGAAAGA  GAAAATTGAT  1140
1141  CGGCGCTCTG  GCAAGAAGCT  GGAAGATAAC  CCCAAATCCC  TGAAATCTGG  AGATGCTGCC  1200
1201  ATTGTGGAAA  TGATCCCTGG  GAAGCCCATG  TGTGTGGAGA  GCTTCTCCCA  GTATCCACCC  1260
1261  CTTGGTCGCT  TCGCTGTGCG  GGACATGAGG  CAGACTGTGG  CTGTCGGCGT  CATCAAGAAC  1320
1321  GTCGAGAAGA  AGAGTGGAGG  GGCAGGCAAA  GTGACCAAGT  CTGCACAGAA  GGCCCAGAAA  1380
1381  GCTGGGAAAT  GA  1392

▼ KEYWORD

ID
Family
Complete proteome
Elongation factor
GTP-binding
Nucleotide-binding
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Translation elongation factor activity

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ora-0021Ornithorhynchus anatinus100.00.0 951
LLPS-Fia-2591Ficedula albicollis100.00.0 951
LLPS-Tag-0967Taeniopygia guttata100.00.0 952
LLPS-Pes-1254Pelodiscus sinensis99.780.0 950
LLPS-Gaga-0559Gallus gallus99.780.0 949
LLPS-Anc-3596Anolis carolinensis99.570.0 949
LLPS-Sus-0571Sus scrofa99.350.0 944
LLPS-Cea-0993Cercocebus atys99.350.0 948
LLPS-Aon-0720Aotus nancymaae99.350.0 948
LLPS-Maf-2342Macaca fascicularis99.350.0 948
LLPS-Chs-1440Chlorocebus sabaeus99.350.0 948
LLPS-Caj-1462Callithrix jacchus99.350.0 948
LLPS-Bot-2222Bos taurus99.350.0 948
LLPS-Paa-0083Papio anubis99.350.0 948
LLPS-Man-0643Macaca nemestrina99.350.0 948
LLPS-Pat-2178Pan troglodytes99.350.0 948
LLPS-Otg-2241Otolemur garnettii99.350.0 948
LLPS-Cap-1547Cavia porcellus99.350.0 948
LLPS-Nol-3951Nomascus leucogenys99.350.0 948
LLPS-Fud-2462Fukomys damarensis99.30.0 887
LLPS-Mal-2112Mandrillus leucophaeus99.290.0 867
LLPS-Ict-4575Ictidomys tridecemlineatus99.290.0 869
LLPS-Mum-0726Mus musculus99.140.0 947
LLPS-Mea-0619Mesocricetus auratus99.140.0 945
LLPS-Ran-0200Rattus norvegicus99.140.0 947
LLPS-Fec-2955Felis catus99.140.0 947
LLPS-Xet-2064Xenopus tropicalis99.140.0 943
LLPS-Tut-1304Tursiops truncatus98.920.0 939
LLPS-Loa-2715Loxodonta africana98.830.0 875
LLPS-Mup-1483Mustela putorius furo98.810.0 865
LLPS-Rhb-0380Rhinopithecus bieti98.70.0 942
LLPS-Aim-2698Ailuropoda melanoleuca97.670.0 870
LLPS-Urm-1981Ursus maritimus97.670.0 870
LLPS-Hos-2069Homo sapiens97.190.0 926
LLPS-Leo-1630Lepisosteus oculatus96.980.0 932
LLPS-Scf-0881Scleropages formosus95.680.0 919
LLPS-Dar-2675Danio rerio94.380.0 910
LLPS-Asm-0707Astyanax mexicanus93.950.0 908
LLPS-Icp-2208Ictalurus punctatus93.520.0 906
LLPS-Anp-0246Anas platyrhynchos92.840.0 892
LLPS-Meg-2585Meleagris gallopavo92.840.0 892
LLPS-Myl-0197Myotis lucifugus92.620.0 890
LLPS-Ten-1602Tetraodon nigroviridis92.610.0 889
LLPS-Gog-1174Gorilla gorilla92.410.0 890
LLPS-Ova-2121Ovis aries92.410.0 890
LLPS-Pap-3872Pan paniscus92.410.0 890
LLPS-Orc-2866Oryctolagus cuniculus92.410.0 890
LLPS-Mam-0494Macaca mulatta92.410.0 890
LLPS-Poa-3031Pongo abelii92.410.0 890
LLPS-Caf-1529Canis familiaris92.410.0 890
LLPS-Eqc-1432Equus caballus92.410.0 890
LLPS-Dio-0217Dipodomys ordii92.190.0 887
LLPS-Mod-2181Monodelphis domestica92.190.0 888
LLPS-Orn-1000Oreochromis niloticus92.190.0 885
LLPS-Cas-3574Carlito syrichta92.190.0 889
LLPS-Xim-1406Xiphophorus maculatus91.970.0 883
LLPS-Pof-0581Poecilia formosa91.970.0 883
LLPS-Gaa-2233Gasterosteus aculeatus91.30.0 880
LLPS-Scm-0290Scophthalmus maximus90.870.0 813
LLPS-Lac-3741Latimeria chalumnae90.220.0 867
LLPS-Tar-0687Takifugu rubripes89.350.0 843
LLPS-Orl-1101Oryzias latipes89.130.0 865
LLPS-Cae-1606Caenorhabditis elegans84.930.0 817
LLPS-Drm-1604Drosophila melanogaster84.020.0 825
LLPS-Cis-1509Ciona savignyi82.530.0 781
LLPS-Cii-1838Ciona intestinalis82.10.0 788
LLPS-Miv-0526Microbotryum violaceum81.190.0 775
LLPS-Nec-1445Neurospora crassa81.020.0 777
LLPS-Asg-0864Ashbya gossypii80.430.0 776
LLPS-Scs-0035Sclerotinia sclerotiorum80.350.0 764
LLPS-Coo-0161Colletotrichum orbiculare80.350.0 773
LLPS-Fuv-1338Fusarium verticillioides80.130.0 770
LLPS-Mel-0450Melampsora laricipopulina80.130.0 773
LLPS-Trr-0140Trichoderma reesei80.130.0 767
LLPS-Scp-0321Schizosaccharomyces pombe80.090.0 768
LLPS-Cogr-0071Colletotrichum graminicola80.040.0 785
LLPS-Pytr-0366Pyrenophora triticirepentis80.00.0 771
LLPS-Sac-1187Saccharomyces cerevisiae79.910.0 756
LLPS-Beb-0492Beauveria bassiana79.830.0 781
LLPS-Kop-1070Komagataella pastoris79.690.0 763
LLPS-Nef-1081Neosartorya fischeri79.610.0 785
LLPS-Lem-1156Leptosphaeria maculans79.570.0 764
LLPS-Scj-0167Schizosaccharomyces japonicus79.570.0 775
LLPS-Dos-1004Dothistroma septosporum79.510.0 754
LLPS-Pyt-0448Pyrenophora teres79.480.0 763
LLPS-Pug-0332Puccinia graminis79.420.0 767
LLPS-Fuo-0468Fusarium oxysporum79.40.0 732
LLPS-Asc-0786Aspergillus clavatus79.30.0 775
LLPS-Fus-0148Fusarium solani79.250.0 765
LLPS-Asfu-0115Aspergillus fumigatus79.250.0 771
LLPS-Trv-0177Trichoderma virens79.160.0 758
LLPS-Spr-1037Sporisorium reilianum79.080.0 781
LLPS-Usm-0916Ustilago maydis78.770.0 775
LLPS-Zyt-0398Zymoseptoria tritici78.760.0 745
LLPS-Phn-1410Phaeosphaeria nodorum78.620.0 756
LLPS-Cog-1446Colletotrichum gloeosporioides78.590.0 747
LLPS-Scc-0584Schizosaccharomyces cryophilus78.380.0 765
LLPS-Orbr-1640Oryza brachyantha78.380.0 718
LLPS-Orb-1453Oryza barthii78.150.0 717
LLPS-Ori-0122Oryza indica78.150.0 717
LLPS-Yal-0190Yarrowia lipolytica78.150.0 752
LLPS-Orni-1920Oryza nivara78.150.0 717
LLPS-Ors-0930Oryza sativa78.150.0 717
LLPS-Org-1512Oryza glaberrima78.150.0 717
LLPS-Ast-0634Aspergillus terreus78.120.0 757
LLPS-Crn-0041Cryptococcus neoformans78.10.0 753
LLPS-Blg-0925Blumeria graminis78.10.0 745
LLPS-Asn-1218Aspergillus nidulans78.040.0 771
LLPS-Orp-0316Oryza punctata77.980.0 713
LLPS-Asf-0318Aspergillus flavus77.870.0 765
LLPS-Lep-2161Leersia perrieri77.70.0 715
LLPS-Brd-1791Brachypodium distachyon77.70.0 713
LLPS-Aso-0526Aspergillus oryzae77.510.0 761
LLPS-Sob-1702Sorghum bicolor77.480.0 711
LLPS-Zem-1334Zea mays77.480.0 712
LLPS-Cym-0514Cyanidioschyzon merolae77.260.0 718
LLPS-Ved-0320Verticillium dahliae77.040.0 746
LLPS-Sei-0820Setaria italica77.030.0 709
LLPS-Put-0261Puccinia triticina76.990.0 732
LLPS-Via-0233Vigna angularis76.910.0 727
LLPS-Vir-1095Vigna radiata76.910.0 728
LLPS-Gor-2507Gossypium raimondii76.910.0 730
LLPS-Glm-0124Glycine max76.80.0 710
LLPS-Hea-1368Helianthus annuus76.80.0 706
LLPS-Amt-0656Amborella trichopoda76.690.0 724
LLPS-Coc-0924Corchorus capsularis76.690.0 725
LLPS-Thc-1793Theobroma cacao76.670.0 726
LLPS-Mae-0899Manihot esculenta76.670.0 726
LLPS-Prp-1348Prunus persica76.580.0 705
LLPS-Gas-0616Galdieria sulphuraria76.40.0 705
LLPS-Tru-0952Triticum urartu76.370.0 713
LLPS-Sem-2250Selaginella moellendorffii76.350.0 708
LLPS-Met-0003Medicago truncatula76.30.0 719
LLPS-Hov-0940Hordeum vulgare76.250.0 716
LLPS-Tra-2512Triticum aestivum76.250.0 714
LLPS-Viv-0600Vitis vinifera76.250.0 722
LLPS-Php-2463Physcomitrella patens76.130.0 703
LLPS-Phv-1536Phaseolus vulgaris76.030.0 723
LLPS-Pot-1005Populus trichocarpa75.930.0 718
LLPS-Nia-1021Nicotiana attenuata75.60.0 718
LLPS-Sol-0761Solanum lycopersicum75.380.0 719
LLPS-Brn-1469Brassica napus75.270.0 712
LLPS-Dac-0254Daucus carota75.270.0 708
LLPS-Brr-2524Brassica rapa75.270.0 711
LLPS-Bro-0690Brassica oleracea75.270.0 711
LLPS-Sot-1266Solanum tuberosum75.220.0 716
LLPS-Mao-0072Magnaporthe oryzae75.160.0 736
LLPS-Art-1043Arabidopsis thaliana75.050.0 710
LLPS-Map-0651Magnaporthe poae74.950.0 734
LLPS-Gag-1009Gaeumannomyces graminis74.730.0 741