• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pat-2178
EEF1A2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Elongation factor 1-alpha
Gene Name: EEF1A2, CK820_G0037283
Ensembl Gene: ENSPTRG00000013737.4
Ensembl Protein: ENSPTRP00000023661.4
Organism: Pan troglodytes
Taxa ID: 9598
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGKEKTHINI  VVIGHVDSGK  STTTGHLIYK  CGGIDKRTIE  KFEKEAAEMG  KGSFKYAWVL  60
61    DKLKAERERG  ITIDISLWKF  ETTKYYITII  DAPGHRDFIK  NMITGTSQAD  CAVLIVAAGV  120
121   GEFEAGISKN  GQTREHALLA  YTLGVKQLIV  GVNKMDSTEP  AYSEKRYDEI  VKEVSAYIKK  180
181   IGYNPATVPF  VPISGWHGDN  MLEPSPNMPW  FKGWKVERKE  GNASGVSLLE  ALDTILPPTR  240
241   PTDKPLRLPL  QDVYKIGGIG  TVPVGRVETG  ILRPGMVVTF  APVNITTEVK  SVEMHHEALS  300
301   EALPGDNVGF  NVKNVSVKDI  RRGNVCGDSK  SDPPQEAAQF  TSQVIILNHP  GQISAGYSPV  360
361   IDCHTAHIAC  KFAELKEKID  RRSGKKLEDN  PKSLKSGDAA  IVEMVPGKPM  CVESFSQYPP  420
421   LGRFAVRDMR  QTVAVGVIKN  VEKKSGGAGK  VTKSAQKAQK  AGK  463
Nucleotide CDS Sequence (FASTA)
1     ATGGGCAAGG  AGAAGACCCA  CATCAACATC  GTGGTCATCG  GCCACGTGGA  CTCCGGAAAG  60
61    TCCACCACCA  CGGGCCACCT  CATCTACAAA  TGCGGAGGTA  TTGACAAAAG  GACCATTGAG  120
121   AAGTTCGAGA  AGGAGGCGGC  TGAGATGGGG  AAGGGATCCT  TCAAATATGC  CTGGGTGCTG  180
181   GACAAGCTGA  AGGCGGAGCG  TGAGCGCGGC  ATCACCATCG  ACATCTCCCT  CTGGAAGTTC  240
241   GAGACCACCA  AGTACTACAT  CACCATCATC  GATGCCCCCG  GCCACCGCGA  CTTCATCAAG  300
301   AACATGATCA  CGGGTACATC  CCAGGCGGAC  TGCGCAGTGC  TGATCGTGGC  GGCGGGCGTG  360
361   GGCGAGTTCG  AGGCGGGCAT  CTCCAAGAAT  GGGCAGACGC  GGGAGCATGC  CCTGCTGGCC  420
421   TACACGCTGG  GTGTGAAGCA  GCTCATCGTG  GGCGTGAACA  AAATGGACTC  CACAGAGCCG  480
481   GCCTACAGCG  AGAAGCGCTA  CGACGAGATC  GTCAAGGAAG  TCAGCGCCTA  CATCAAGAAG  540
541   ATCGGCTACA  ACCCGGCCAC  CGTGCCCTTT  GTGCCCATCT  CCGGCTGGCA  CGGCGACAAC  600
601   ATGCTGGAGC  CCTCCCCCAA  CATGCCGTGG  TTCAAGGGCT  GGAAGGTGGA  GCGTAAGGAG  660
661   GGCAACGCAA  GCGGCGTGTC  CCTGCTGGAG  GCCCTGGACA  CCATCCTGCC  CCCCACGCGC  720
721   CCCACGGACA  AGCCCCTGCG  TCTGCCGCTG  CAGGACGTGT  ACAAGATCGG  TGGCATTGGC  780
781   ACGGTGCCCG  TGGGCCGGGT  GGAGACCGGC  ATCCTGCGGC  CGGGCATGGT  GGTGACCTTT  840
841   GCGCCAGTGA  ACATCACCAC  TGAGGTGAAG  TCAGTGGAGA  TGCACCACGA  GGCTCTGAGC  900
901   GAAGCTCTGC  CCGGCGACAA  CGTCGGCTTC  AATGTGAAGA  ACGTGTCGGT  GAAGGACATC  960
961   CGGCGGGGCA  ACGTGTGTGG  GGACAGCAAG  TCTGACCCGC  CGCAGGAGGC  TGCTCAGTTC  1020
1021  ACCTCCCAGG  TCATCATCCT  GAACCACCCG  GGGCAGATTA  GCGCCGGCTA  CTCCCCGGTC  1080
1081  ATCGACTGCC  ACACAGCCCA  CATCGCCTGC  AAGTTTGCGG  AGCTGAAGGA  GAAGATTGAC  1140
1141  CGGCGCTCTG  GCAAGAAGCT  GGAGGACAAC  CCCAAGTCCC  TGAAGTCTGG  AGACGCGGCC  1200
1201  ATCGTGGAGA  TGGTGCCGGG  AAAGCCCATG  TGTGTGGAGA  GCTTCTCCCA  GTACCCGCCT  1260
1261  CTCGGCCGCT  TCGCCGTGCG  CGACATGAGG  CAGACGGTGG  CCGTGGGCGT  CATCAAGAAC  1320
1321  GTGGAGAAGA  AGAGCGGGGG  CGCCGGCAAG  GTCACCAAGT  CGGCGCAGAA  GGCGCAGAAG  1380
1381  GCGGGCAAGT  GA  1392

▼ KEYWORD

ID
Family
Complete proteome
Elongation factor
GTP-binding
Nucleotide-binding
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Eukaryotic translation elongation factor 1 complex
Cellular Component
Synapse
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Protein kinase binding
Molecular Function
Translation elongation factor activity
Biological Process
Positive regulation of apoptotic process
Biological Process
Positive regulation of lipid kinase activity

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-0643Macaca nemestrina100.00.0 952
LLPS-Otg-2241Otolemur garnettii100.00.0 952
LLPS-Cap-1547Cavia porcellus100.00.0 952
LLPS-Ict-4575Ictidomys tridecemlineatus100.00.0 873
LLPS-Nol-3951Nomascus leucogenys100.00.0 952
LLPS-Aon-0720Aotus nancymaae100.00.0 952
LLPS-Cea-0993Cercocebus atys100.00.0 952
LLPS-Sus-0571Sus scrofa100.00.0 948
LLPS-Maf-2342Macaca fascicularis100.00.0 952
LLPS-Chs-1440Chlorocebus sabaeus100.00.0 952
LLPS-Fud-2462Fukomys damarensis100.00.0 891
LLPS-Caj-1462Callithrix jacchus100.00.0 952
LLPS-Bot-2222Bos taurus100.00.0 952
LLPS-Paa-0083Papio anubis100.00.0 952
LLPS-Mal-2112Mandrillus leucophaeus100.00.0 871
LLPS-Fec-2955Felis catus99.780.0 951
LLPS-Mea-0619Mesocricetus auratus99.780.0 949
LLPS-Mum-0726Mus musculus99.780.0 951
LLPS-Ran-0200Rattus norvegicus99.780.0 951
LLPS-Gaga-0559Gallus gallus99.570.0 951
LLPS-Tut-1304Tursiops truncatus99.570.0 944
LLPS-Mup-1483Mustela putorius furo99.520.0 870
LLPS-Fia-2591Ficedula albicollis99.350.0 948
LLPS-Rhb-0380Rhinopithecus bieti99.350.0 946
LLPS-Tag-0967Taeniopygia guttata99.350.0 948
LLPS-Sah-2199Sarcophilus harrisii99.350.0 948
LLPS-Ora-0021Ornithorhynchus anatinus99.350.0 948
LLPS-Pes-1254Pelodiscus sinensis99.140.0 947
LLPS-Anc-3596Anolis carolinensis98.920.0 946
LLPS-Loa-2715Loxodonta africana98.590.0 872
LLPS-Xet-2064Xenopus tropicalis98.490.0 940
LLPS-Urm-1981Ursus maritimus98.370.0 874
LLPS-Aim-2698Ailuropoda melanoleuca98.370.0 874
LLPS-Hos-2069Homo sapiens97.840.0 930
LLPS-Leo-1630Lepisosteus oculatus97.190.0 931
LLPS-Scf-0881Scleropages formosus95.90.0 917
LLPS-Dar-2675Danio rerio94.380.0 912
LLPS-Asm-0707Astyanax mexicanus94.170.0 907
LLPS-Icp-2208Ictalurus punctatus93.520.0 907
LLPS-Anp-0246Anas platyrhynchos92.620.0 889
LLPS-Pap-3872Pan paniscus92.620.0 887
LLPS-Meg-2585Meleagris gallopavo92.620.0 889
LLPS-Orc-2866Oryctolagus cuniculus92.620.0 887
LLPS-Mam-0494Macaca mulatta92.620.0 887
LLPS-Poa-3031Pongo abelii92.620.0 887
LLPS-Caf-1529Canis familiaris92.620.0 887
LLPS-Eqc-1432Equus caballus92.620.0 887
LLPS-Gog-1174Gorilla gorilla92.620.0 887
LLPS-Ova-2121Ovis aries92.620.0 887
LLPS-Mod-2181Monodelphis domestica92.410.0 886
LLPS-Cas-3574Carlito syrichta92.410.0 887
LLPS-Dio-0217Dipodomys ordii92.410.0 885
LLPS-Myl-0197Myotis lucifugus92.410.0 887
LLPS-Ten-1602Tetraodon nigroviridis92.170.0 889
LLPS-Pof-0581Poecilia formosa91.970.0 884
LLPS-Xim-1406Xiphophorus maculatus91.970.0 884
LLPS-Orn-1000Oreochromis niloticus91.760.0 885
LLPS-Gaa-2233Gasterosteus aculeatus90.870.0 879
LLPS-Lac-3741Latimeria chalumnae90.430.0 865
LLPS-Scm-0290Scophthalmus maximus90.40.0 812
LLPS-Orl-1101Oryzias latipes89.350.0 863
LLPS-Tar-0687Takifugu rubripes89.350.0 844
LLPS-Cae-1606Caenorhabditis elegans84.50.0 813
LLPS-Drm-1604Drosophila melanogaster84.230.0 823
LLPS-Cis-1509Ciona savignyi82.750.0 781
LLPS-Cii-1838Ciona intestinalis82.310.0 790
LLPS-Miv-0526Microbotryum violaceum80.970.0 775
LLPS-Nec-1445Neurospora crassa80.570.0 776
LLPS-Scp-0321Schizosaccharomyces pombe80.530.0 771
LLPS-Asg-0864Ashbya gossypii80.430.0 776
LLPS-Sac-1187Saccharomyces cerevisiae80.360.0 757
LLPS-Scs-0035Sclerotinia sclerotiorum80.350.0 764
LLPS-Coo-0161Colletotrichum orbiculare80.350.0 773
LLPS-Mel-0450Melampsora laricipopulina80.130.0 774
LLPS-Cogr-0071Colletotrichum graminicola80.040.0 785
LLPS-Pytr-0366Pyrenophora triticirepentis80.00.0 771
LLPS-Scj-0167Schizosaccharomyces japonicus80.00.0 777
LLPS-Beb-0492Beauveria bassiana79.830.0 782
LLPS-Trr-0140Trichoderma reesei79.690.0 766
LLPS-Fuv-1338Fusarium verticillioides79.690.0 770
LLPS-Kop-1070Komagataella pastoris79.690.0 764
LLPS-Lem-1156Leptosphaeria maculans79.570.0 764
LLPS-Spr-1037Sporisorium reilianum79.520.0 783
LLPS-Asc-0786Aspergillus clavatus79.520.0 775
LLPS-Pyt-0448Pyrenophora teres79.480.0 763
LLPS-Asfu-0115Aspergillus fumigatus79.470.0 771
LLPS-Pug-0332Puccinia graminis79.420.0 768
LLPS-Fuo-0468Fusarium oxysporum79.40.0 734
LLPS-Nef-1081Neosartorya fischeri79.390.0 785
LLPS-Fus-0148Fusarium solani79.250.0 766
LLPS-Dos-1004Dothistroma septosporum79.060.0 753
LLPS-Scc-0584Schizosaccharomyces cryophilus78.820.0 766
LLPS-Usm-0916Ustilago maydis78.770.0 775
LLPS-Trv-0177Trichoderma virens78.710.0 757
LLPS-Phn-1410Phaeosphaeria nodorum78.620.0 757
LLPS-Cog-1446Colletotrichum gloeosporioides78.590.0 748
LLPS-Crn-0041Cryptococcus neoformans78.320.0 755
LLPS-Zyt-0398Zymoseptoria tritici78.320.0 743
LLPS-Orbr-1640Oryza brachyantha78.150.0 718
LLPS-Yal-0190Yarrowia lipolytica78.150.0 752
LLPS-Ors-0930Oryza sativa77.930.0 717
LLPS-Org-1512Oryza glaberrima77.930.0 717
LLPS-Orb-1453Oryza barthii77.930.0 717
LLPS-Ori-0122Oryza indica77.930.0 717
LLPS-Orni-1920Oryza nivara77.930.0 717
LLPS-Ast-0634Aspergillus terreus77.90.0 756
LLPS-Blg-0925Blumeria graminis77.880.0 745
LLPS-Asn-1218Aspergillus nidulans77.830.0 771
LLPS-Orp-0316Oryza punctata77.750.0 713
LLPS-Sob-1702Sorghum bicolor77.70.0 712
LLPS-Zem-1334Zea mays77.70.0 714
LLPS-Asf-0318Aspergillus flavus77.660.0 764
LLPS-Lep-2161Leersia perrieri77.480.0 716
LLPS-Brd-1791Brachypodium distachyon77.480.0 713
LLPS-Aso-0526Aspergillus oryzae77.290.0 761
LLPS-Cym-0514Cyanidioschyzon merolae77.260.0 720
LLPS-Glm-0124Glycine max77.030.0 711
LLPS-Hea-1368Helianthus annuus77.030.0 707
LLPS-Put-0261Puccinia triticina76.990.0 733
LLPS-Thc-1793Theobroma cacao76.890.0 726
LLPS-Sei-0820Setaria italica76.80.0 710
LLPS-Gor-2507Gossypium raimondii76.690.0 730
LLPS-Via-0233Vigna angularis76.690.0 728
LLPS-Vir-1095Vigna radiata76.690.0 728
LLPS-Ved-0320Verticillium dahliae76.610.0 746
LLPS-Amt-0656Amborella trichopoda76.470.0 724
LLPS-Coc-0924Corchorus capsularis76.470.0 726
LLPS-Mae-0899Manihot esculenta76.460.0 726
LLPS-Gas-0616Galdieria sulphuraria76.40.0 706
LLPS-Prp-1348Prunus persica76.350.0 706
LLPS-Sem-2250Selaginella moellendorffii76.350.0 708
LLPS-Tru-0952Triticum urartu76.150.0 713
LLPS-Met-0003Medicago truncatula76.090.0 719
LLPS-Viv-0600Vitis vinifera76.030.0 722
LLPS-Hov-0940Hordeum vulgare76.030.0 716
LLPS-Tra-2512Triticum aestivum76.030.0 715
LLPS-Php-2463Physcomitrella patens75.90.0 703
LLPS-Phv-1536Phaseolus vulgaris75.820.0 724
LLPS-Pot-1005Populus trichocarpa75.710.0 719
LLPS-Nia-1021Nicotiana attenuata75.60.0 719
LLPS-Map-0651Magnaporthe poae75.380.0 735
LLPS-Brr-0762Brassica rapa75.270.0 714
LLPS-Bro-0690Brassica oleracea75.270.0 712
LLPS-Brn-1469Brassica napus75.270.0 712
LLPS-Dac-0254Daucus carota75.270.0 709
LLPS-Sol-0761Solanum lycopersicum75.160.0 719
LLPS-Gag-1009Gaeumannomyces graminis75.160.0 742
LLPS-Mao-0072Magnaporthe oryzae75.160.0 736
LLPS-Art-1043Arabidopsis thaliana75.050.0 711
LLPS-Sot-1266Solanum tuberosum75.00.0 716