LLPS-Pytr-0924
PTRG_01485
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 |
| Gene Name: | PTRG_01485 |
| Ensembl Gene: | PTRG_01485 |
| Ensembl Protein: | EDU40923 |
| Organism: | Pyrenophora triticirepentis |
| Taxa ID: | 426418 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EDU40923 | EDU40923 |
| UniProt | B2VWC3, B2VWC3_PYRTR | |
| GeneBank | DS231615 | EDU40923.1 |
| RefSeq | XM_001931783.1 | XP_001931818.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAVPTLEGAP VLSTPDTHIF EDPTPAVDTT NLPRLSDEQV ALTYEIERTV REIREGQWKR 60 61 IALQFPDHML TDAPRVYEHL SRGLKKERKG QNGIQDRSGQ SNGATTEEEL SAKLEKASIQ 120 121 ESEDIEERLF ILGDTSYGAC CVDEVAAEHV DADVVVHYGR SCLSPPSRLP VIYIFTERPL 180 181 DLEAVMATFR ETYADKEAKI ILMADIPYSH HIPTLYKCLC DDGYTHVHAT EIVHNPSSPL 240 241 PNRTIPATVT DTDEGLREYA LFHISDPPAS LLLTLSSRVA SIHIYPTTTT SPTPATASLA 300 301 STARTLSRRY ALLTSLSTTP IFGILINTLS VKNYMHILSH VQQQIATAGK KSYTFVVGKV 360 361 NAAKVANFSE VGGWVVIGCW ESSLIESSEF WRPMITPWEL GLALKRDEER VWTGAWEADF 420 421 QKVLDGEKGD VKETNGGDGA AAGTGAAQEH EQNQVDDDSE EESAPPEFDL RTGRYVSNAR 480 481 PMRSTQSAKV TNGQAVPSSS SALTKRANGD IAAVGGVASP GAEYLRSNRT WQGLGSDYQN 540 541 GEEDGSGEVT GGRAAKMEEG RSGIAKGYVV GEEGRIH 577 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCGTCC CGACCCTTGA AGGCGCTCCT GTGCTCTCTA CCCCCGATAC ACACATCTTC 60 61 GAAGACCCGA CACCCGCAGT AGACACGACC AATCTTCCCA GACTATCAGA TGAGCAGGTC 120 121 GCACTCACGT ACGAAATCGA ACGGACGGTT AGGGAAATTA GGGAGGGACA ATGGAAAAGG 180 181 ATCGCGCTGC AGTTTCCGGA TCACATGCTC ACGGATGCAC CGCGGGTATA TGAACACCTG 240 241 AGTCGAGGCC TAAAAAAAGA ACGTAAAGGA CAGAATGGGA TACAAGACAG GAGTGGTCAA 300 301 TCCAACGGGG CGACAACAGA AGAAGAGTTA AGCGCAAAAC TTGAGAAAGC CAGTATACAA 360 361 GAATCAGAGG ATATTGAAGA AAGGCTGTTC ATCCTAGGCG ATACATCATA TGGTGCATGC 420 421 TGCGTGGACG AAGTCGCTGC AGAGCATGTC GATGCAGACG TTGTGGTGCA CTATGGCCGT 480 481 TCATGTCTCT CGCCTCCCTC CAGACTTCCA GTCATATACA TATTCACAGA AAGACCACTA 540 541 GACCTAGAAG CGGTAATGGC AACATTCAGA GAGACATACG CAGACAAAGA GGCAAAGATT 600 601 ATACTCATGG CAGATATCCC CTATTCACAC CACATCCCTA CCCTCTACAA ATGCCTCTGC 660 661 GACGACGGCT ACACACACGT ACACGCAACG GAGATTGTCC ACAATCCATC TTCACCCCTA 720 721 CCAAACCGAA CGATACCAGC CACAGTAACG GATACCGACG AAGGTCTCCG CGAATACGCC 780 781 TTATTCCACA TATCCGACCC GCCCGCCTCT CTCCTCCTTA CCCTATCCTC GCGCGTCGCT 840 841 TCCATTCACA TCTACCCCAC GACAACCACC TCGCCCACAC CCGCAACAGC CTCGCTCGCC 900 901 AGCACCGCCC GTACCCTCAG CCGCCGCTAC GCCCTCCTAA CCTCACTCTC CACAACCCCC 960 961 ATCTTCGGCA TCCTCATCAA CACCCTCTCC GTCAAAAACT ACATGCACAT CCTCTCGCAC 1020 1021 GTACAACAGC AAATCGCGAC TGCAGGCAAA AAGAGCTATA CGTTCGTCGT GGGCAAAGTC 1080 1081 AACGCGGCAA AGGTGGCAAA CTTCAGTGAA GTGGGCGGCT GGGTGGTGAT TGGATGTTGG 1140 1141 GAAAGTAGTT TGATTGAAAG TAGTGAGTTT TGGCGGCCGA TGATTACGCC GTGGGAACTC 1200 1201 GGTTTGGCGC TTAAGAGAGA TGAGGAGAGG GTGTGGACGG GGGCTTGGGA GGCGGATTTC 1260 1261 CAAAAAGTTT TAGATGGTGA GAAGGGGGAT GTGAAGGAAA CGAATGGTGG TGATGGTGCT 1320 1321 GCAGCGGGTA CCGGAGCCGC TCAGGAACAT GAGCAAAACC AGGTCGATGA TGACTCTGAA 1380 1381 GAGGAATCCG CTCCTCCGGA ATTCGACTTG AGGACTGGTC GCTACGTATC GAACGCACGA 1440 1441 CCTATGCGCT CGACTCAGTC GGCCAAGGTT ACCAATGGTC AGGCAGTACC GTCGTCTAGT 1500 1501 TCTGCATTAA CAAAACGTGC CAATGGCGAT ATAGCGGCAG TGGGTGGCGT AGCTTCACCA 1560 1561 GGTGCCGAGT ACCTACGCTC CAACAGGACA TGGCAGGGTC TGGGGAGCGA CTACCAAAAT 1620 1621 GGCGAAGAGG ACGGTAGTGG CGAAGTGACA GGGGGTAGAG CGGCAAAGAT GGAAGAGGGG 1680 1681 AGGAGTGGGA TTGCGAAGGG TTATGTTGTT GGTGAAGAGG GGAGGATACA CTAG 1734 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | Transferase activity | |
Biological Process | Peptidyl-diphthamide biosynthetic process from peptidyl-histidine |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pyt-1139 | Pyrenophora teres | 92.03 | 0.0 | 942 |
| LLPS-Phn-0827 | Phaeosphaeria nodorum | 71.82 | 0.0 | 737 |
| LLPS-Lem-1576 | Leptosphaeria maculans | 67.18 | 0.0 | 649 |
| LLPS-Nef-0599 | Neosartorya fischeri | 55.17 | 0.0 | 530 |
| LLPS-Asfu-1063 | Aspergillus fumigatus | 55.0 | 0.0 | 533 |
| LLPS-Aso-1385 | Aspergillus oryzae | 55.0 | 6e-180 | 528 |
| LLPS-Asf-0877 | Aspergillus flavus | 55.0 | 6e-180 | 528 |
| LLPS-Asc-0946 | Aspergillus clavatus | 54.87 | 0.0 | 537 |
| LLPS-Dos-1553 | Dothistroma septosporum | 54.55 | 1e-175 | 517 |
| LLPS-Asn-0368 | Aspergillus nidulans | 54.03 | 2e-175 | 516 |
| LLPS-Ast-0364 | Aspergillus terreus | 52.68 | 7e-55 | 198 |
| LLPS-Asni-0116 | Aspergillus niger | 52.41 | 7e-168 | 495 |
| LLPS-Scs-0187 | Sclerotinia sclerotiorum | 51.9 | 2e-163 | 485 |
| LLPS-Zyt-0637 | Zymoseptoria tritici | 51.38 | 2e-154 | 462 |
| LLPS-Blg-1343 | Blumeria graminis | 47.02 | 3e-105 | 339 |
| LLPS-Trr-0186 | Trichoderma reesei | 46.79 | 1e-138 | 421 |
| LLPS-Nec-0330 | Neurospora crassa | 46.52 | 3e-136 | 416 |
| LLPS-Trv-1062 | Trichoderma virens | 46.05 | 4e-135 | 411 |
| LLPS-Ved-0269 | Verticillium dahliae | 45.83 | 2e-128 | 395 |
| LLPS-Gag-1099 | Gaeumannomyces graminis | 45.25 | 9e-125 | 386 |
| LLPS-Cogr-1487 | Colletotrichum graminicola | 44.98 | 2e-123 | 380 |
| LLPS-Coo-0080 | Colletotrichum orbiculare | 44.92 | 3e-120 | 372 |
| LLPS-Fus-1606 | Fusarium solani | 44.86 | 5e-132 | 404 |
| LLPS-Scf-3766 | Scleropages formosus | 44.44 | 2e-19 | 95.5 |
| LLPS-Beb-1538 | Beauveria bassiana | 44.17 | 2e-118 | 366 |
| LLPS-Fuo-1118 | Fusarium oxysporum | 43.66 | 1e-127 | 392 |
| LLPS-Tum-1244 | Tuber melanosporum | 43.22 | 9e-98 | 316 |
| LLPS-Fuv-0696 | Fusarium verticillioides | 43.03 | 7e-129 | 395 |
| LLPS-Mao-1631 | Magnaporthe oryzae | 42.39 | 5e-121 | 377 |
| LLPS-Sol-1792 | Solanum lycopersicum | 40.87 | 2e-14 | 80.9 |
| LLPS-Php-1706 | Physcomitrella patens | 40.19 | 9e-12 | 71.6 |
| LLPS-Mua-0698 | Musa acuminata | 40.0 | 2e-13 | 77.0 |
| LLPS-Usm-1450 | Ustilago maydis | 39.06 | 7e-17 | 88.6 |
| LLPS-Mae-0311 | Manihot esculenta | 37.93 | 1e-13 | 77.4 |
| LLPS-Miv-0461 | Microbotryum violaceum | 37.78 | 3e-18 | 92.4 |
| LLPS-Viv-2303 | Vitis vinifera | 37.43 | 6e-15 | 81.6 |
| LLPS-Pot-1118 | Populus trichocarpa | 37.4 | 1e-13 | 77.8 |
| LLPS-Cis-0954 | Ciona savignyi | 36.75 | 1e-13 | 75.5 |
| LLPS-Thc-1828 | Theobroma cacao | 36.29 | 1e-13 | 78.2 |
| LLPS-Spr-0685 | Sporisorium reilianum | 35.94 | 3e-13 | 76.6 |
| LLPS-Nia-1497 | Nicotiana attenuata | 35.62 | 3e-16 | 85.9 |
| LLPS-Gor-1434 | Gossypium raimondii | 35.48 | 9e-14 | 78.2 |
| LLPS-Sem-0619 | Selaginella moellendorffii | 35.37 | 2e-28 | 121 |
| LLPS-Dio-3973 | Dipodomys ordii | 34.27 | 5e-15 | 82.0 |
| LLPS-Asg-1200 | Ashbya gossypii | 33.86 | 2e-62 | 222 |
| LLPS-Icp-0832 | Ictalurus punctatus | 33.83 | 5e-45 | 171 |
| LLPS-Sei-1497 | Setaria italica | 33.72 | 2e-16 | 86.7 |
| LLPS-Dar-0561 | Danio rerio | 33.66 | 1e-46 | 176 |
| LLPS-Scp-1309 | Schizosaccharomyces pombe | 33.4 | 6e-53 | 194 |
| LLPS-Mod-3331 | Monodelphis domestica | 33.33 | 7e-13 | 75.1 |
| LLPS-Zem-2444 | Zea mays | 33.33 | 1e-16 | 87.0 |
| LLPS-Scc-1609 | Schizosaccharomyces cryophilus | 33.21 | 4e-55 | 200 |
| LLPS-Leo-2643 | Lepisosteus oculatus | 33.01 | 1e-45 | 173 |
| LLPS-Asm-2796 | Astyanax mexicanus | 32.92 | 1e-44 | 170 |
| LLPS-Pug-0683 | Puccinia graminis | 32.85 | 5e-12 | 72.8 |
| LLPS-Xim-2984 | Xiphophorus maculatus | 32.77 | 2e-43 | 167 |
| LLPS-Scj-1418 | Schizosaccharomyces japonicus | 32.65 | 3e-45 | 172 |
| LLPS-Brd-0002 | Brachypodium distachyon | 32.56 | 4e-11 | 69.7 |
| LLPS-Gaga-2757 | Gallus gallus | 32.36 | 3e-35 | 143 |
| LLPS-Orn-3416 | Oreochromis niloticus | 32.3 | 1e-42 | 164 |
| LLPS-Cap-0221 | Cavia porcellus | 32.02 | 2e-13 | 77.0 |
| LLPS-Sah-3930 | Sarcophilus harrisii | 31.97 | 5e-08 | 59.7 |
| LLPS-Pof-1351 | Poecilia formosa | 31.96 | 6e-44 | 168 |
| LLPS-Cus-1352 | Cucumis sativus | 31.77 | 1e-14 | 80.9 |
| LLPS-Hos-3998 | Homo sapiens | 31.46 | 6e-14 | 78.6 |
| LLPS-Man-4283 | Macaca nemestrina | 31.46 | 2e-14 | 80.1 |
| LLPS-Brn-1708 | Brassica napus | 31.4 | 3e-14 | 76.6 |
| LLPS-Arl-1705 | Arabidopsis lyrata | 31.4 | 1e-13 | 77.8 |
| LLPS-Orc-3570 | Oryctolagus cuniculus | 31.37 | 9e-15 | 81.3 |
| LLPS-Sac-0075 | Saccharomyces cerevisiae | 31.18 | 2e-54 | 198 |
| LLPS-Gaa-2826 | Gasterosteus aculeatus | 31.08 | 2e-38 | 151 |
| LLPS-Eqc-3547 | Equus caballus | 31.0 | 9e-15 | 81.3 |
| LLPS-Kop-0345 | Komagataella pastoris | 30.93 | 9e-49 | 183 |
| LLPS-Ten-0773 | Tetraodon nigroviridis | 30.85 | 3e-49 | 183 |
| LLPS-Art-2774 | Arabidopsis thaliana | 30.81 | 2e-13 | 77.0 |
| LLPS-Brr-2179 | Brassica rapa | 30.64 | 4e-35 | 142 |
| LLPS-Met-2521 | Medicago truncatula | 30.51 | 7e-13 | 75.5 |
| LLPS-Mam-0937 | Macaca mulatta | 30.5 | 1e-14 | 80.9 |
| LLPS-Chs-1280 | Chlorocebus sabaeus | 30.5 | 5e-14 | 79.0 |
| LLPS-Maf-2172 | Macaca fascicularis | 30.5 | 4e-14 | 79.3 |
| LLPS-Paa-1927 | Papio anubis | 30.5 | 4e-14 | 79.0 |
| LLPS-Lac-0294 | Latimeria chalumnae | 30.46 | 3e-47 | 178 |
| LLPS-Anc-0850 | Anolis carolinensis | 30.35 | 3e-39 | 154 |
| LLPS-Scm-1688 | Scophthalmus maximus | 30.33 | 1e-47 | 179 |
| LLPS-Via-2088 | Vigna angularis | 30.26 | 1e-16 | 85.1 |
| LLPS-Tar-2626 | Takifugu rubripes | 30.19 | 2e-38 | 152 |
| LLPS-Fia-0245 | Ficedula albicollis | 30.09 | 5e-47 | 177 |
| LLPS-Meg-1473 | Meleagris gallopavo | 29.7 | 6e-43 | 165 |
| LLPS-Bot-3778 | Bos taurus | 29.17 | 4e-21 | 100 |
| LLPS-Yal-0186 | Yarrowia lipolytica | 29.01 | 6e-40 | 156 |
| LLPS-Xet-1269 | Xenopus tropicalis | 28.87 | 8e-36 | 144 |
| LLPS-Sot-2068 | Solanum tuberosum | 28.84 | 9e-30 | 126 |
| LLPS-Orl-1427 | Oryzias latipes | 28.81 | 2e-45 | 172 |
| LLPS-Fud-1009 | Fukomys damarensis | 28.8 | 2e-22 | 104 |
| LLPS-Ova-1333 | Ovis aries | 28.61 | 5e-21 | 100 |
| LLPS-Ori-0422 | Oryza indica | 28.57 | 2e-17 | 88.6 |
| LLPS-Orb-1611 | Oryza barthii | 28.57 | 2e-17 | 88.6 |
| LLPS-Hea-2105 | Helianthus annuus | 28.57 | 1e-30 | 129 |
| LLPS-Coc-1734 | Corchorus capsularis | 28.44 | 8e-15 | 81.3 |
| LLPS-Osl-0801 | Ostreococcus lucimarinus | 28.41 | 2e-14 | 80.1 |
| LLPS-Mel-0675 | Melampsora laricipopulina | 28.3 | 3e-32 | 134 |
| LLPS-Caf-4085 | Canis familiaris | 28.05 | 5e-21 | 100 |
| LLPS-Aim-0972 | Ailuropoda melanoleuca | 28.01 | 3e-22 | 103 |
| LLPS-Ict-1602 | Ictidomys tridecemlineatus | 27.97 | 1e-22 | 105 |
| LLPS-Cas-0090 | Carlito syrichta | 27.89 | 3e-20 | 98.2 |
| LLPS-Bro-2350 | Brassica oleracea | 27.85 | 6e-36 | 144 |
| LLPS-Drm-1318 | Drosophila melanogaster | 27.84 | 5e-18 | 91.3 |
| LLPS-Dac-1362 | Daucus carota | 27.8 | 8e-29 | 124 |
| LLPS-Urm-3757 | Ursus maritimus | 27.75 | 7e-22 | 103 |
| LLPS-Aon-4212 | Aotus nancymaae | 27.75 | 4e-20 | 97.8 |
| LLPS-Mum-4880 | Mus musculus | 27.65 | 4e-21 | 100 |
| LLPS-Orni-1639 | Oryza nivara | 27.62 | 3e-36 | 145 |
| LLPS-Caj-0475 | Callithrix jacchus | 27.59 | 4e-19 | 94.7 |
| LLPS-Pat-4479 | Pan troglodytes | 27.44 | 1e-20 | 99.8 |
| LLPS-Pap-3878 | Pan paniscus | 27.44 | 1e-20 | 99.4 |
| LLPS-Mup-0808 | Mustela putorius furo | 27.39 | 3e-22 | 104 |
| LLPS-Ors-2217 | Oryza sativa | 27.27 | 4e-36 | 145 |
| LLPS-Orr-2081 | Oryza rufipogon | 27.27 | 2e-36 | 146 |
| LLPS-Org-1287 | Oryza glaberrima | 27.27 | 7e-36 | 144 |
| LLPS-Orgl-2338 | Oryza glumaepatula | 27.27 | 9e-36 | 144 |
| LLPS-Orm-1943 | Oryza meridionalis | 27.2 | 5e-31 | 130 |
| LLPS-Sob-1805 | Sorghum bicolor | 27.07 | 4e-34 | 139 |
| LLPS-Prp-0629 | Prunus persica | 26.75 | 4e-29 | 124 |
| LLPS-Otg-2153 | Otolemur garnettii | 26.67 | 2e-20 | 99.0 |
| LLPS-Lep-0056 | Leersia perrieri | 26.53 | 2e-31 | 131 |
| LLPS-Cii-1999 | Ciona intestinalis | 26.5 | 3e-24 | 110 |
| LLPS-Hov-1546 | Hordeum vulgare | 26.49 | 5e-36 | 145 |
| LLPS-Ran-1178 | Rattus norvegicus | 26.44 | 9e-23 | 105 |
| LLPS-Tru-1737 | Triticum urartu | 26.43 | 6e-33 | 137 |
| LLPS-Mea-3913 | Mesocricetus auratus | 26.3 | 3e-20 | 98.2 |
| LLPS-Loa-0721 | Loxodonta africana | 26.23 | 2e-21 | 102 |
| LLPS-Nol-4502 | Nomascus leucogenys | 26.0 | 5e-21 | 100 |
| LLPS-Gog-1212 | Gorilla gorilla | 25.96 | 1e-20 | 99.4 |
| LLPS-Mal-4161 | Mandrillus leucophaeus | 25.96 | 6e-21 | 100 |
| LLPS-Fec-4522 | Felis catus | 25.82 | 5e-23 | 106 |
| LLPS-Orp-1942 | Oryza punctata | 25.73 | 2e-31 | 131 |
| LLPS-Crn-1196 | Cryptococcus neoformans | 25.64 | 1e-28 | 123 |
| LLPS-Phv-2437 | Phaseolus vulgaris | 25.31 | 5e-30 | 127 |
| LLPS-Glm-0398 | Glycine max | 24.81 | 1e-26 | 118 |