• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Put-0792
PTTG_03773

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Histone H4
Gene Name: PTTG_03773, PTTG_03776, PTTG_04742, PTTG_06581, PTTG_07651, PTTG_09137
Ensembl Gene: PTTG_03773
Ensembl Protein: PTTG_03773P0
Organism: Puccinia triticina
Taxa ID: 630390
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSGRGKSGGK  GLGKGGAKRH  RKILRDNIQG  ITKPAIRRLA  RRGGVKRISG  LIYEETRGVL  60
61    KIFLENVIRD  SVTYTEHAKR  KTVTSLDVVY  ALKRQGRTLY  GFGA  104
Nucleotide CDS Sequence (FASTA)
1     ATGTCTGGAC  GCGGAAAGAG  CGGCGGAAAG  GGCCTCGGCA  AGGGCGGTGC  CAAACGTCAC  60
61    CGCAAGATCT  TGCGGGACAA  CATCCAAGGT  ATCACCAAGC  CGGCCATCCG  AAGACTTGCC  120
121   CGTCGAGGAG  GAGTCAAGCG  AATCTCCGGG  CTGATCTACG  AAGAGACCCG  CGGGGTGCTG  180
181   AAAATCTTTC  TCGAGAATGT  CATCCGGGAC  TCCGTCACCT  ACACCGAGCA  CGCCAAGCGG  240
241   AAAACGGTCA  CCTCGCTCGA  TGTCGTCTAT  GCCCTCAAGC  GACAGGGCCG  GACACTCTAC  300
301   GGCTTCGGAG  CA  312

▼ KEYWORD

ID
Family
Chromosome
Complete proteome
DNA-binding
Nucleosome core
Nucleus
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleosome
Cellular Component
Nucleus
Molecular Function
DNA binding
Molecular Function
Protein heterodimerization activity
Biological Process
Nucleosome assembly

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pug-0813Puccinia graminis100.03e-51 163
LLPS-Mel-0312Melampsora laricipopulina100.03e-51 163
LLPS-Crn-0310Cryptococcus neoformans98.786e-51 162
LLPS-Miv-0214Microbotryum violaceum98.771e-49 160
LLPS-Spr-0266Sporisorium reilianum96.342e-49 159
LLPS-Usm-0755Ustilago maydis96.342e-49 159
LLPS-Abg-0180Absidia glauca96.341e-49 159
LLPS-Cis-0294Ciona savignyi95.065e-49 161
LLPS-Sac-1159Saccharomyces cerevisiae93.93e-47 153
LLPS-Asfu-0406Aspergillus fumigatus93.832e-47 154
LLPS-Gor-0062Gossypium raimondii93.839e-49 159
LLPS-Phv-0839Phaseolus vulgaris93.833e-48 158
LLPS-Sob-0572Sorghum bicolor93.837e-49 160
LLPS-Lem-0600Leptosphaeria maculans93.836e-47 156
LLPS-Kop-0192Komagataella pastoris93.834e-47 152
LLPS-Brd-0624Brachypodium distachyon93.832e-48 159
LLPS-Hov-0272Hordeum vulgare93.837e-49 159
LLPS-Sem-0538Selaginella moellendorffii93.834e-48 155
LLPS-Hea-1065Helianthus annuus93.837e-49 160
LLPS-Arl-1462Arabidopsis lyrata93.595e-46 150
LLPS-Prp-0437Prunus persica92.682e-48 156
LLPS-Fuo-0964Fusarium oxysporum92.684e-47 153
LLPS-Trv-0271Trichoderma virens92.685e-47 152
LLPS-Mam-1622Macaca mulatta92.687e-49 157
LLPS-Pytr-0504Pyrenophora triticirepentis92.682e-47 154
LLPS-Eqc-0619Equus caballus92.687e-49 157
LLPS-Cap-0578Cavia porcellus92.687e-49 157
LLPS-Orm-0397Oryza meridionalis92.682e-48 156
LLPS-Orr-0298Oryza rufipogon92.682e-48 156
LLPS-Poa-0232Pongo abelii92.687e-49 157
LLPS-Ten-1565Tetraodon nigroviridis92.687e-49 157
LLPS-Caf-0576Canis familiaris92.687e-49 157
LLPS-Coc-0352Corchorus capsularis92.682e-48 156
LLPS-Tru-0020Triticum urartu92.682e-48 156
LLPS-Cogr-0604Colletotrichum graminicola92.685e-47 152
LLPS-Phn-0096Phaeosphaeria nodorum92.682e-47 154
LLPS-Tag-1576Taeniopygia guttata92.687e-49 157
LLPS-Ict-0419Ictidomys tridecemlineatus92.687e-49 157
LLPS-Org-0221Oryza glaberrima92.682e-48 156
LLPS-Anc-0833Anolis carolinensis92.687e-49 157
LLPS-Nol-1078Nomascus leucogenys92.687e-49 157
LLPS-Zem-0328Zea mays92.682e-48 156
LLPS-Bro-0448Brassica oleracea92.682e-48 156
LLPS-Dos-0092Dothistroma septosporum92.684e-47 153
LLPS-Gaga-0704Gallus gallus92.687e-49 157
LLPS-Xet-0331Xenopus tropicalis92.687e-49 157
LLPS-Cas-0991Carlito syrichta92.687e-49 157
LLPS-Ved-0497Verticillium dahliae92.685e-47 152
LLPS-Pot-0544Populus trichocarpa92.682e-48 156
LLPS-Anp-1907Anas platyrhynchos92.687e-49 157
LLPS-Orp-0480Oryza punctata92.682e-48 156
LLPS-Loa-1489Loxodonta africana92.687e-49 157
LLPS-Ast-0386Aspergillus terreus92.683e-47 153
LLPS-Man-1523Macaca nemestrina92.687e-49 157
LLPS-Lac-0577Latimeria chalumnae92.687e-49 157
LLPS-Art-0418Arabidopsis thaliana92.682e-48 156
LLPS-Scm-1600Scophthalmus maximus92.687e-49 157
LLPS-Fec-0807Felis catus92.687e-49 157
LLPS-Mod-0671Monodelphis domestica92.687e-49 157
LLPS-Ors-0700Oryza sativa92.682e-48 156
LLPS-Brr-1059Brassica rapa92.682e-48 156
LLPS-Pat-2482Pan troglodytes92.687e-49 157
LLPS-Pof-0887Poecilia formosa92.687e-49 157
LLPS-Urm-1433Ursus maritimus92.687e-49 157
LLPS-Pap-0724Pan paniscus92.687e-49 157
LLPS-Viv-0467Vitis vinifera92.682e-48 156
LLPS-Dar-0749Danio rerio92.687e-49 157
LLPS-Hos-1834Homo sapiens92.687e-49 157
LLPS-Meg-0377Meleagris gallopavo92.687e-49 157
LLPS-Nia-1183Nicotiana attenuata92.682e-48 156
LLPS-Orn-0302Oreochromis niloticus92.687e-49 157
LLPS-Rhb-1128Rhinopithecus bieti92.687e-49 157
LLPS-Fus-0272Fusarium solani92.683e-47 152
LLPS-Nef-0419Neosartorya fischeri92.683e-47 153
LLPS-Fia-1551Ficedula albicollis92.687e-49 157
LLPS-Amt-0348Amborella trichopoda92.682e-48 156
LLPS-Mae-1045Manihot esculenta92.682e-48 156
LLPS-Orc-0467Oryctolagus cuniculus92.687e-49 157
LLPS-Trr-0900Trichoderma reesei92.685e-47 152
LLPS-Orbr-0086Oryza brachyantha92.682e-48 156
LLPS-Pes-0421Pelodiscus sinensis92.685e-49 157
LLPS-Cog-0657Colletotrichum gloeosporioides92.685e-47 152
LLPS-Otg-0041Otolemur garnettii92.687e-49 157
LLPS-Bot-0405Bos taurus92.687e-49 157
LLPS-Scf-0750Scleropages formosus92.687e-49 157
LLPS-Sot-1228Solanum tuberosum92.682e-48 156
LLPS-Blg-0369Blumeria graminis92.684e-47 153
LLPS-Aso-0946Aspergillus oryzae92.682e-47 153
LLPS-Dio-1050Dipodomys ordii92.687e-49 157
LLPS-Gaa-1421Gasterosteus aculeatus92.687e-49 157
LLPS-Lep-0362Leersia perrieri92.682e-48 156
LLPS-Orgl-0437Oryza glumaepatula92.682e-48 156
LLPS-Tut-0897Tursiops truncatus92.687e-49 157
LLPS-Tar-0618Takifugu rubripes92.687e-49 157
LLPS-Drm-0331Drosophila melanogaster92.688e-49 157
LLPS-Xim-1327Xiphophorus maculatus92.687e-49 157
LLPS-Via-0106Vigna angularis92.682e-48 156
LLPS-Pyt-0724Pyrenophora teres92.682e-47 154
LLPS-Tum-0275Tuber melanosporum92.684e-47 153
LLPS-Mup-0089Mustela putorius furo92.687e-49 157
LLPS-Aim-0221Ailuropoda melanoleuca92.687e-49 157
LLPS-Myl-0177Myotis lucifugus92.687e-49 157
LLPS-Ova-2058Ovis aries92.686e-49 157
LLPS-Zyt-0179Zymoseptoria tritici92.684e-47 153
LLPS-Mal-0719Mandrillus leucophaeus92.687e-49 157
LLPS-Paa-2406Papio anubis92.687e-49 157
LLPS-Vir-0658Vigna radiata92.682e-48 156
LLPS-Asf-0231Aspergillus flavus92.682e-47 153
LLPS-Nec-1129Neurospora crassa92.684e-47 153
LLPS-Ere-0135Erinaceus europaeus92.687e-49 157
LLPS-Tra-0677Triticum aestivum92.682e-48 156
LLPS-Cus-1036Cucumis sativus92.682e-48 156
LLPS-Sei-0527Setaria italica92.681e-48 157
LLPS-Ran-0020Rattus norvegicus92.687e-49 157
LLPS-Met-1109Medicago truncatula92.682e-48 156
LLPS-Cea-2108Cercocebus atys92.687e-49 157
LLPS-Sah-1507Sarcophilus harrisii92.687e-49 157
LLPS-Aon-0281Aotus nancymaae92.687e-49 157
LLPS-Ori-0776Oryza indica92.682e-48 156
LLPS-Sus-0102Sus scrofa92.687e-49 157
LLPS-Brn-0121Brassica napus92.682e-48 156
LLPS-Orb-0513Oryza barthii92.682e-48 156
LLPS-Orl-0563Oryzias latipes92.687e-49 157
LLPS-Scs-0272Sclerotinia sclerotiorum92.684e-47 153
LLPS-Chs-1589Chlorocebus sabaeus92.687e-49 157
LLPS-Ora-0027Ornithorhynchus anatinus92.687e-49 157
LLPS-Asc-0569Aspergillus clavatus92.683e-47 153
LLPS-Glm-0119Glycine max92.682e-48 156
LLPS-Mea-2792Mesocricetus auratus92.687e-49 157
LLPS-Sol-1228Solanum lycopersicum92.682e-48 156
LLPS-Fuv-0256Fusarium verticillioides92.684e-47 153
LLPS-Maf-2295Macaca fascicularis92.687e-49 157
LLPS-Gag-0133Gaeumannomyces graminis92.685e-47 152
LLPS-Mum-0813Mus musculus92.687e-49 157
LLPS-Mao-0970Magnaporthe oryzae92.685e-47 152
LLPS-Icp-2614Ictalurus punctatus92.681e-48 156
LLPS-Dac-0265Daucus carota92.682e-48 156
LLPS-Map-0042Magnaporthe poae92.685e-47 152
LLPS-Caj-0194Callithrix jacchus92.687e-49 157
LLPS-Thc-0226Theobroma cacao92.682e-48 157
LLPS-Asm-0373Astyanax mexicanus92.687e-49 157
LLPS-Fud-1065Fukomys damarensis92.687e-49 157
LLPS-Orni-0640Oryza nivara92.682e-48 156
LLPS-Mua-0622Musa acuminata92.682e-48 156
LLPS-Asn-0905Aspergillus nidulans92.682e-47 153
LLPS-Asni-0398Aspergillus niger92.683e-47 153
LLPS-Coo-0359Colletotrichum orbiculare92.685e-47 152
LLPS-Php-0013Physcomitrella patens92.682e-48 156
LLPS-Gog-1638Gorilla gorilla92.687e-49 157
LLPS-Yal-0244Yarrowia lipolytica92.597e-46 149
LLPS-Osl-0587Ostreococcus lucimarinus91.462e-48 156
LLPS-Beb-0083Beauveria bassiana91.462e-46 150
LLPS-Chr-0974Chlamydomonas reinhardtii91.463e-47 153
LLPS-Cae-0458Caenorhabditis elegans91.463e-48 155
LLPS-Asg-0515Ashbya gossypii91.463e-46 150
LLPS-Scp-0833Schizosaccharomyces pombe91.364e-47 153
LLPS-Scj-0275Schizosaccharomyces japonicus91.365e-47 152
LLPS-Scc-0325Schizosaccharomyces cryophilus90.122e-46 150
LLPS-Chc-0082Chondrus crispus89.027e-47 152
LLPS-Cym-0453Cyanidioschyzon merolae89.024e-46 150
LLPS-Gas-0315Galdieria sulphuraria87.83e-46 150
LLPS-Leo-2073Lepisosteus oculatus87.658e-45 147