DrLLPS - Data resource of LLPS

LLPS-Chs-1589

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Histone H4
Ensembl Gene:	ENSCSAG00000019238.1
Ensembl Protein:	ENSCSAP00000018748.1
Organism:	Chlorocebus sabaeus
Taxa ID:	60711
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Chromatin, Nucleolus, Chromatoid body	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Mus musculus	LLPS-Mum-0813	P62806	Client	Chromatin	100.00	3e-51	163
Rattus norvegicus	LLPS-Ran-0020	P62804	Client	Chromatoid body	100.00	3e-51	163
Arabidopsis thaliana	LLPS-Art-0418	P59259	Client	Nucleolus	97.56	1e-50	161
Oreochromis niloticus	LLPS-Orn-0302	P62796	Client	Nucleolus	100.00	3e-51	163

▼ FUNCTION

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSCSAT00000019328.1	ENSCSAP00000018748.1
UniProt		A0A0D9SD09, A0A0D9SD09_CHLSB
GeneBank	AQIB01128542
RefSeq	XM_007973426.1, XM_007973463.1, XM_007973475.1, XM_007973476.1, XM_008019821.1, XM_008019822.1	XP_007971617.1, XP_007971654.1, XP_007971666.1, XP_007971667.1, XP_008018012.1, XP_008018013.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK 60 61 VFLENVIRDA VTYTEHAKRK TVTAMDVVYA LKRQGRTLYG FGG 103
Nucleotide CDS Sequence (FASTA)
1 ATGTCTGGGC GCGGTAAAGG CGGCAAGGGG CTGGGTAAGG GAGGCGCCAA GCGCCACCGG 60 61 AAGGTGTTGC GGGACAATAT CCAAGGCATT ACAAAGCCCG CGATTCGCCG TCTCGCCCGA 120 121 CGTGGGGGCG TCAAGCGCAT CTCTGGTCTC ATTTACGAGG AGACCCGGGG AGTCCTCAAA 180 181 GTCTTCCTGG AGAACGTGAT CCGCGACGCG GTGACTTACA CGGAGCACGC CAAGCGCAAG 240 241 ACCGTCACGG CCATGGATGT GGTGTACGCG CTGAAACGCC AGGGTCGCAC CCTCTATGGT 300 301 TTCGGCGGC 309

▼ KEYWORD

ID	Family
KW-0158	Chromosome
KW-0181	Complete proteome
KW-0238	DNA-binding
KW-0544	Nucleosome core
KW-0539	Nucleus
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0000786	Cellular Component	Nucleosome
GO:0005634	Cellular Component	Nucleus
GO:0003677	Molecular Function	DNA binding
GO:0046982	Molecular Function	Protein heterodimerization activity
GO:0006352	Biological Process	DNA-templated transcription, initiation
GO:0006334	Biological Process	Nucleosome assembly

▼ KEGG

csab:103221971

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Dar-0749	Danio rerio	100.0	3e-51	163
LLPS-Meg-0377	Meleagris gallopavo	100.0	3e-51	163
LLPS-Hos-1834	Homo sapiens	100.0	3e-51	163
LLPS-Pat-2482	Pan troglodytes	100.0	3e-51	163
LLPS-Pof-0887	Poecilia formosa	100.0	3e-51	163
LLPS-Urm-1433	Ursus maritimus	100.0	3e-51	163
LLPS-Pap-0724	Pan paniscus	100.0	3e-51	163
LLPS-Scm-1600	Scophthalmus maximus	100.0	3e-51	163
LLPS-Fec-0807	Felis catus	100.0	3e-51	163
LLPS-Mod-0671	Monodelphis domestica	100.0	3e-51	163
LLPS-Lac-0577	Latimeria chalumnae	100.0	3e-51	163
LLPS-Man-1523	Macaca nemestrina	100.0	3e-51	163
LLPS-Anp-1907	Anas platyrhynchos	100.0	3e-51	163
LLPS-Loa-1489	Loxodonta africana	100.0	3e-51	163
LLPS-Otg-0041	Otolemur garnettii	100.0	3e-51	163
LLPS-Pes-0421	Pelodiscus sinensis	100.0	3e-51	163
LLPS-Orc-0467	Oryctolagus cuniculus	100.0	3e-51	163
LLPS-Fia-1551	Ficedula albicollis	100.0	3e-51	163
LLPS-Orn-0302	Oreochromis niloticus	100.0	3e-51	163
LLPS-Rhb-1128	Rhinopithecus bieti	100.0	3e-51	163
LLPS-Poa-0232	Pongo abelii	100.0	3e-51	163
LLPS-Ten-1565	Tetraodon nigroviridis	100.0	3e-51	163
LLPS-Caf-0576	Canis familiaris	100.0	3e-51	163
LLPS-Cap-0578	Cavia porcellus	100.0	3e-51	163
LLPS-Eqc-0619	Equus caballus	100.0	3e-51	163
LLPS-Mam-1622	Macaca mulatta	100.0	3e-51	163
LLPS-Gaga-0704	Gallus gallus	100.0	3e-51	163
LLPS-Xet-0331	Xenopus tropicalis	100.0	3e-51	163
LLPS-Cas-0991	Carlito syrichta	100.0	3e-51	163
LLPS-Anc-0833	Anolis carolinensis	100.0	3e-51	163
LLPS-Nol-1078	Nomascus leucogenys	100.0	3e-51	163
LLPS-Ict-0419	Ictidomys tridecemlineatus	100.0	3e-51	163
LLPS-Tag-1576	Taeniopygia guttata	100.0	3e-51	163
LLPS-Tru-0025	Triticum urartu	100.0	3e-51	163
LLPS-Maf-2295	Macaca fascicularis	100.0	3e-51	163
LLPS-Mum-0813	Mus musculus	100.0	3e-51	163
LLPS-Mea-2792	Mesocricetus auratus	100.0	3e-51	163
LLPS-Ora-0027	Ornithorhynchus anatinus	100.0	3e-51	163
LLPS-Orl-0563	Oryzias latipes	100.0	3e-51	163
LLPS-Sus-0102	Sus scrofa	100.0	3e-51	163
LLPS-Cea-2108	Cercocebus atys	100.0	3e-51	163
LLPS-Sah-1507	Sarcophilus harrisii	100.0	3e-51	163
LLPS-Aon-0281	Aotus nancymaae	100.0	3e-51	163
LLPS-Gog-1638	Gorilla gorilla	100.0	3e-51	163
LLPS-Asm-0373	Astyanax mexicanus	100.0	3e-51	163
LLPS-Fud-1065	Fukomys damarensis	100.0	3e-51	163
LLPS-Caj-0194	Callithrix jacchus	100.0	3e-51	163
LLPS-Xim-1327	Xiphophorus maculatus	100.0	3e-51	163
LLPS-Drm-0331	Drosophila melanogaster	100.0	4e-51	163
LLPS-Tut-0897	Tursiops truncatus	100.0	3e-51	163
LLPS-Tar-0618	Takifugu rubripes	100.0	3e-51	163
LLPS-Dio-1050	Dipodomys ordii	100.0	3e-51	163
LLPS-Gaa-1421	Gasterosteus aculeatus	100.0	3e-51	163
LLPS-Scf-0750	Scleropages formosus	100.0	3e-51	163
LLPS-Bot-0405	Bos taurus	100.0	3e-51	163
LLPS-Ran-0020	Rattus norvegicus	100.0	3e-51	163
LLPS-Ere-0135	Erinaceus europaeus	100.0	3e-51	163
LLPS-Paa-2406	Papio anubis	100.0	3e-51	163
LLPS-Mal-0719	Mandrillus leucophaeus	100.0	3e-51	163
LLPS-Mup-0089	Mustela putorius furo	100.0	3e-51	163
LLPS-Aim-0221	Ailuropoda melanoleuca	100.0	3e-51	163
LLPS-Ova-2058	Ovis aries	100.0	2e-51	164
LLPS-Myl-0177	Myotis lucifugus	100.0	3e-51	163
LLPS-Osl-0587	Ostreococcus lucimarinus	98.78	1e-50	162
LLPS-Cis-1193	Ciona savignyi	98.78	7e-51	166
LLPS-Cae-0458	Caenorhabditis elegans	98.78	1e-50	161
LLPS-Icp-2614	Ictalurus punctatus	98.78	2e-50	161
LLPS-Viv-0467	Vitis vinifera	97.56	1e-50	162
LLPS-Ors-0700	Oryza sativa	97.56	1e-50	162
LLPS-Brr-1059	Brassica rapa	97.56	1e-50	162
LLPS-Gor-0062	Gossypium raimondii	97.56	4e-51	165
LLPS-Art-0418	Arabidopsis thaliana	97.56	1e-50	162
LLPS-Pot-0544	Populus trichocarpa	97.56	1e-50	162
LLPS-Orp-0480	Oryza punctata	97.56	1e-50	162
LLPS-Sob-0572	Sorghum bicolor	97.56	4e-51	166
LLPS-Orbr-0086	Oryza brachyantha	97.56	1e-50	162
LLPS-Phv-0839	Phaseolus vulgaris	97.56	1e-50	164
LLPS-Mae-1045	Manihot esculenta	97.56	1e-50	162
LLPS-Amt-0348	Amborella trichopoda	97.56	1e-50	162
LLPS-Nia-1183	Nicotiana attenuata	97.56	1e-50	162
LLPS-Coc-0352	Corchorus capsularis	97.56	1e-50	162
LLPS-Orm-0397	Oryza meridionalis	97.56	1e-50	162
LLPS-Orr-0298	Oryza rufipogon	97.56	1e-50	162
LLPS-Prp-0437	Prunus persica	97.56	1e-50	162
LLPS-Bro-0448	Brassica oleracea	97.56	1e-50	162
LLPS-Org-0221	Oryza glaberrima	97.56	1e-50	162
LLPS-Zem-0328	Zea mays	97.56	1e-50	162
LLPS-Glm-0119	Glycine max	97.56	1e-50	162
LLPS-Sol-1228	Solanum lycopersicum	97.56	1e-50	162
LLPS-Brn-0121	Brassica napus	97.56	1e-50	162
LLPS-Orb-0513	Oryza barthii	97.56	1e-50	162
LLPS-Ori-0776	Oryza indica	97.56	1e-50	162
LLPS-Hea-1065	Helianthus annuus	97.56	2e-51	166
LLPS-Php-0013	Physcomitrella patens	97.56	1e-50	162
LLPS-Mua-0622	Musa acuminata	97.56	1e-50	162
LLPS-Orni-0640	Oryza nivara	97.56	1e-50	162
LLPS-Thc-0226	Theobroma cacao	97.56	1e-50	163
LLPS-Dac-0265	Daucus carota	97.56	1e-50	162
LLPS-Via-0106	Vigna angularis	97.56	1e-50	162
LLPS-Orgl-0437	Oryza glumaepatula	97.56	1e-50	162
LLPS-Lep-0362	Leersia perrieri	97.56	1e-50	162
LLPS-Sot-1228	Solanum tuberosum	97.56	1e-50	162
LLPS-Hov-0272	Hordeum vulgare	97.56	5e-51	165
LLPS-Met-1109	Medicago truncatula	97.56	1e-50	162
LLPS-Cus-1036	Cucumis sativus	97.56	1e-50	162
LLPS-Sei-0527	Setaria italica	97.56	6e-51	163
LLPS-Tra-0677	Triticum aestivum	97.56	1e-50	162
LLPS-Brd-0624	Brachypodium distachyon	97.56	1e-50	164
LLPS-Vir-0658	Vigna radiata	97.56	1e-50	162
LLPS-Sem-0538	Selaginella moellendorffii	97.53	5e-50	160
LLPS-Arl-1462	Arabidopsis lyrata	97.44	2e-47	153
LLPS-Abg-0180	Absidia glauca	96.34	5e-50	160
LLPS-Chr-0974	Chlamydomonas reinhardtii	95.12	7e-49	157
LLPS-Gas-0315	Galdieria sulphuraria	95.12	1e-48	157
LLPS-Crn-0310	Cryptococcus neoformans	93.9	4e-49	157
LLPS-Leo-2073	Lepisosteus oculatus	93.9	2e-47	153
LLPS-Cym-0453	Cyanidioschyzon merolae	93.9	3e-48	155
LLPS-Pug-0813	Puccinia graminis	92.68	7e-49	157
LLPS-Put-0792	Puccinia triticina	92.68	7e-49	157
LLPS-Mel-0312	Melampsora laricipopulina	92.68	7e-49	157
LLPS-Chc-0082	Chondrus crispus	92.68	1e-47	154
LLPS-Miv-0214	Microbotryum violaceum	92.59	2e-48	157
LLPS-Ast-0386	Aspergillus terreus	91.46	1e-47	154
LLPS-Cog-0657	Colletotrichum gloeosporioides	91.46	4e-47	153
LLPS-Trr-0900	Trichoderma reesei	91.46	4e-47	153
LLPS-Nef-0419	Neosartorya fischeri	91.46	1e-47	154
LLPS-Fus-0272	Fusarium solani	91.46	2e-47	153
LLPS-Pytr-0504	Pyrenophora triticirepentis	91.46	7e-48	154
LLPS-Trv-0271	Trichoderma virens	91.46	4e-47	153
LLPS-Fuo-0964	Fusarium oxysporum	91.46	3e-47	153
LLPS-Ved-0497	Verticillium dahliae	91.46	4e-47	153
LLPS-Dos-0092	Dothistroma septosporum	91.46	3e-47	153
LLPS-Asfu-0406	Aspergillus fumigatus	91.46	8e-48	155
LLPS-Phn-0096	Phaeosphaeria nodorum	91.46	7e-48	154
LLPS-Cogr-0604	Colletotrichum graminicola	91.46	4e-47	153
LLPS-Gag-0133	Gaeumannomyces graminis	91.46	4e-47	153
LLPS-Fuv-0256	Fusarium verticillioides	91.46	3e-47	153
LLPS-Asc-0569	Aspergillus clavatus	91.46	1e-47	154
LLPS-Scs-0272	Sclerotinia sclerotiorum	91.46	3e-47	153
LLPS-Asni-0398	Aspergillus niger	91.46	1e-47	154
LLPS-Asn-0905	Aspergillus nidulans	91.46	9e-48	154
LLPS-Coo-0359	Colletotrichum orbiculare	91.46	4e-47	153
LLPS-Map-0042	Magnaporthe poae	91.46	4e-47	153
LLPS-Mao-0970	Magnaporthe oryzae	91.46	4e-47	153
LLPS-Kop-0192	Komagataella pastoris	91.46	2e-47	154
LLPS-Pyt-0724	Pyrenophora teres	91.46	7e-48	154
LLPS-Lem-0600	Leptosphaeria maculans	91.46	2e-47	157
LLPS-Blg-0369	Blumeria graminis	91.46	3e-47	153
LLPS-Aso-0946	Aspergillus oryzae	91.46	9e-48	154
LLPS-Asf-0231	Aspergillus flavus	91.46	9e-48	154
LLPS-Nec-1129	Neurospora crassa	91.46	3e-47	153
LLPS-Zyt-0179	Zymoseptoria tritici	91.46	3e-47	153
LLPS-Tum-0275	Tuber melanosporum	91.46	3e-47	153
LLPS-Beb-0083	Beauveria bassiana	90.24	2e-46	151
LLPS-Usm-0755	Ustilago maydis	90.24	2e-47	153
LLPS-Spr-0266	Sporisorium reilianum	90.24	2e-47	153
LLPS-Yal-0244	Yarrowia lipolytica	90.24	2e-46	151
LLPS-Asg-0515	Ashbya gossypii	90.24	1e-46	151
LLPS-Sac-1159	Saccharomyces cerevisiae	90.24	7e-47	152
LLPS-Scp-0833	Schizosaccharomyces pombe	89.02	2e-47	153
LLPS-Scj-0275	Schizosaccharomyces japonicus	89.02	3e-47	153
LLPS-Scc-0325	Schizosaccharomyces cryophilus	87.8	1e-46	151

LLPS-Chs-1589

Protein Sequence

Nucleotide Sequence