LLPS-Pug-0443
ADK1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Adenylate kinase; ATP-AMP transphosphorylase; ATP:AMP phosphotransferase; Adenylate kinase cytosolic and mitochondrial; Adenylate monophosphate kinase |
| Gene Name: | ADK1, PGTG_01071 |
| Ensembl Gene: | PGTG_01071 |
| Ensembl Protein: | EFP75740 |
| Organism: | Puccinia graminis |
| Taxa ID: | 418459 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Droplet, Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EFP75740 | EFP75740 |
| UniProt | E3JUL5, E3JUL5_PUCGT | |
| GeneBank | DS178264 | EFP75740.1 |
| RefSeq | XM_003320111.2 | XP_003320159.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQYTPFLLWL TPHVDGGDRP TTTTQQPAEP LGNSANLPAN MATTTTGGTR DSNLPPASLP 60 61 RDQQRQLDQH GGSISGSQAT EISYLKKLVS DLSLKIENLE KQAGSVVSET IKPSPAEQLR 120 121 LVLMGPPGSG KGTQAPRIKD KYCVCHLATG DMLRDQVSKG TPLGKEAKKI MDSGGLVSDE 180 181 IMVNMIKDQL ESNKDCAKGF ILDGFPRTIA QAEKLDEMLA NKKQNLDLAA ELVIDDNLLV 240 241 SRITGRLIHP ASGRSYHREF APPKSPMKDD ITGEPLIARS DDNADTLRKR LLGYHKQTDL 300 301 VAQYYKKRGI WVGVDAAQSQ LTVWNSLLDA FKNCHEKQKQ QGARK 345 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCAATACA CTCCCTTCCT TCTATGGCTT ACCCCCCACG TGGACGGAGG AGACAGACCA 60 61 ACAACCACAA CCCAACAACC AGCTGAACCA CTTGGGAACT CAGCAAACCT CCCAGCGAAC 120 121 ATGGCTACCA CGACTACCGG CGGAACCAGG GACTCTAACT TGCCCCCAGC TAGCTTGCCT 180 181 CGTGACCAAC AGCGTCAACT GGACCAACAT GGCGGGTCCA TCAGTGGCTC ACAAGCTACC 240 241 GAAATCAGCT ACCTCAAGAA ACTCGTCTCC GACTTGTCGT TGAAGATTGA AAACTTGGAA 300 301 AAACAAGCTG GCTCGGTTGT TTCGGAAACC ATTAAACCAT CGCCGGCAGA ACAACTTCGG 360 361 CTCGTTTTAA TGGGACCACC CGGCTCTGGT AAAGGAACCC AAGCGCCCAG GATCAAGGAC 420 421 AAATACTGTG TGTGTCATTT GGCGACTGGT GACATGCTAC GAGATCAAGT GTCCAAGGGC 480 481 ACTCCTCTCG GCAAAGAGGC GAAGAAGATC ATGGATAGCG GGGGCTTAGT GAGTGATGAG 540 541 ATCATGGTCA ACATGATCAA AGACCAACTC GAGAGCAACA AAGATTGTGC CAAAGGGTTC 600 601 ATCTTGGACG GGTTCCCTCG AACGATCGCT CAAGCTGAGA AATTGGACGA GATGTTGGCA 660 661 AATAAGAAGC AAAACTTGGA CTTGGCTGCC GAACTGGTGA TCGATGACAA CCTCCTGGTT 720 721 AGTCGAATTA CTGGCCGACT CATCCATCCA GCCAGTGGTC GATCTTACCA TCGAGAGTTT 780 781 GCTCCACCAA AGTCGCCGAT GAAAGATGAC ATCACTGGAG AACCGTTGAT CGCGCGCTCA 840 841 GACGACAATG CGGACACATT ACGAAAGCGG CTTCTAGGCT ACCACAAACA GACCGACCTG 900 901 GTGGCCCAAT ACTACAAGAA ACGCGGGATC TGGGTCGGCG TGGATGCCGC GCAAAGTCAG 960 961 CTTACCGTCT GGAATAGTCT CTTGGATGCG TTCAAGAATT GCCACGAGAA ACAGAAACAA 1020 1021 CAAGGTGCTC GAAAATAA 1038 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Mitochondrial intermembrane space | |
Molecular Function | Adenylate kinase activity | |
Molecular Function | ATP binding | |
Biological Process | ADP biosynthetic process | |
Biological Process | AMP metabolic process | |
Biological Process | ATP metabolic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Put-0539 | Puccinia triticina | 90.85 | 0.0 | 602 |
| LLPS-Mel-1114 | Melampsora laricipopulina | 76.22 | 2e-166 | 474 |
| LLPS-Aso-1040 | Aspergillus oryzae | 72.43 | 1e-110 | 328 |
| LLPS-Asg-1224 | Ashbya gossypii | 68.84 | 4e-106 | 319 |
| LLPS-Yal-1440 | Yarrowia lipolytica | 68.72 | 1e-102 | 308 |
| LLPS-Asf-1041 | Aspergillus flavus | 67.06 | 6e-116 | 343 |
| LLPS-Miv-1051 | Microbotryum violaceum | 66.54 | 1e-123 | 363 |
| LLPS-Ast-0054 | Aspergillus terreus | 66.53 | 1e-116 | 345 |
| LLPS-Nef-0344 | Neosartorya fischeri | 66.53 | 6e-116 | 343 |
| LLPS-Asfu-1253 | Aspergillus fumigatus | 66.13 | 2e-115 | 342 |
| LLPS-Tum-0155 | Tuber melanosporum | 66.11 | 1e-81 | 254 |
| LLPS-Pyt-0219 | Pyrenophora teres | 65.99 | 3e-111 | 332 |
| LLPS-Asc-1349 | Aspergillus clavatus | 65.74 | 8e-116 | 343 |
| LLPS-Asn-0756 | Aspergillus nidulans | 65.48 | 3e-115 | 342 |
| LLPS-Asni-0903 | Aspergillus niger | 65.48 | 1e-115 | 343 |
| LLPS-Sac-0495 | Saccharomyces cerevisiae | 65.28 | 8e-100 | 301 |
| LLPS-Scp-0879 | Schizosaccharomyces pombe | 64.76 | 2e-96 | 292 |
| LLPS-Phn-0119 | Phaeosphaeria nodorum | 64.54 | 4e-108 | 324 |
| LLPS-Spr-0325 | Sporisorium reilianum | 64.21 | 1e-124 | 367 |
| LLPS-Scj-0014 | Schizosaccharomyces japonicus | 64.06 | 6e-98 | 296 |
| LLPS-Usm-0321 | Ustilago maydis | 63.73 | 3e-123 | 363 |
| LLPS-Lem-1164 | Leptosphaeria maculans | 63.64 | 2e-108 | 325 |
| LLPS-Crn-1273 | Cryptococcus neoformans | 63.4 | 5e-112 | 334 |
| LLPS-Abg-0576 | Absidia glauca | 62.99 | 2e-110 | 329 |
| LLPS-Kop-0574 | Komagataella pastoris | 62.7 | 2e-109 | 327 |
| LLPS-Scc-1065 | Schizosaccharomyces cryophilus | 62.15 | 1e-88 | 272 |
| LLPS-Fus-0783 | Fusarium solani | 61.75 | 1e-107 | 322 |
| LLPS-Scs-0397 | Sclerotinia sclerotiorum | 61.72 | 3e-110 | 330 |
| LLPS-Fuo-1051 | Fusarium oxysporum | 61.35 | 1e-107 | 322 |
| LLPS-Fuv-0733 | Fusarium verticillioides | 60.96 | 2e-106 | 319 |
| LLPS-Trr-1570 | Trichoderma reesei | 60.71 | 1e-108 | 325 |
| LLPS-Blg-0914 | Blumeria graminis | 60.63 | 4e-109 | 327 |
| LLPS-Ved-0811 | Verticillium dahliae | 60.56 | 2e-109 | 327 |
| LLPS-Hea-0536 | Helianthus annuus | 60.41 | 4e-79 | 249 |
| LLPS-Cogr-0943 | Colletotrichum graminicola | 60.39 | 6e-106 | 318 |
| LLPS-Beb-1240 | Beauveria bassiana | 60.32 | 3e-107 | 321 |
| LLPS-Nec-0794 | Neurospora crassa | 60.23 | 2e-105 | 317 |
| LLPS-Fia-0159 | Ficedula albicollis | 60.1 | 1e-80 | 251 |
| LLPS-Pytr-1383 | Pyrenophora triticirepentis | 60.0 | 2e-98 | 299 |
| LLPS-Dos-0898 | Dothistroma septosporum | 60.0 | 1e-101 | 308 |
| LLPS-Trv-0307 | Trichoderma virens | 59.92 | 6e-106 | 318 |
| LLPS-Prp-1204 | Prunus persica | 59.9 | 4e-78 | 246 |
| LLPS-Mae-0067 | Manihot esculenta | 59.69 | 2e-76 | 242 |
| LLPS-Scf-1036 | Scleropages formosus | 59.62 | 5e-85 | 264 |
| LLPS-Tag-2993 | Taeniopygia guttata | 59.6 | 3e-79 | 248 |
| LLPS-Tut-1792 | Tursiops truncatus | 59.52 | 2e-65 | 211 |
| LLPS-Sot-0077 | Solanum tuberosum | 59.39 | 5e-77 | 243 |
| LLPS-Lep-2363 | Leersia perrieri | 59.39 | 5e-78 | 246 |
| LLPS-Sei-0689 | Setaria italica | 59.39 | 3e-79 | 249 |
| LLPS-Drm-1487 | Drosophila melanogaster | 59.36 | 2e-89 | 275 |
| LLPS-Coc-2071 | Corchorus capsularis | 59.3 | 4e-80 | 251 |
| LLPS-Sus-4451 | Sus scrofa | 59.15 | 2e-87 | 270 |
| LLPS-Coo-0474 | Colletotrichum orbiculare | 59.13 | 2e-103 | 312 |
| LLPS-Cog-0477 | Colletotrichum gloeosporioides | 59.13 | 3e-102 | 309 |
| LLPS-Orl-3543 | Oryzias latipes | 59.09 | 2e-89 | 275 |
| LLPS-Ora-3426 | Ornithorhynchus anatinus | 59.09 | 5e-78 | 245 |
| LLPS-Tar-0250 | Takifugu rubripes | 59.09 | 9e-89 | 273 |
| LLPS-Scm-2399 | Scophthalmus maximus | 59.09 | 8e-90 | 276 |
| LLPS-Meg-1031 | Meleagris gallopavo | 59.09 | 1e-78 | 247 |
| LLPS-Gaga-0344 | Gallus gallus | 59.09 | 1e-75 | 245 |
| LLPS-Gor-2434 | Gossypium raimondii | 59.0 | 2e-78 | 247 |
| LLPS-Map-0357 | Magnaporthe poae | 58.98 | 2e-104 | 315 |
| LLPS-Pot-1410 | Populus trichocarpa | 58.95 | 4e-75 | 239 |
| LLPS-Nia-1810 | Nicotiana attenuata | 58.88 | 7e-78 | 246 |
| LLPS-Pes-2208 | Pelodiscus sinensis | 58.88 | 4e-75 | 239 |
| LLPS-Orp-1205 | Oryza punctata | 58.79 | 2e-78 | 247 |
| LLPS-Orm-1071 | Oryza meridionalis | 58.79 | 6e-78 | 246 |
| LLPS-Zyt-0167 | Zymoseptoria tritici | 58.73 | 3e-99 | 301 |
| LLPS-Leo-0075 | Lepisosteus oculatus | 58.6 | 2e-87 | 270 |
| LLPS-Pof-1741 | Poecilia formosa | 58.57 | 4e-85 | 264 |
| LLPS-Sah-1401 | Sarcophilus harrisii | 58.29 | 8e-77 | 241 |
| LLPS-Ori-1133 | Oryza indica | 58.29 | 1e-77 | 245 |
| LLPS-Brn-1839 | Brassica napus | 58.29 | 2e-80 | 252 |
| LLPS-Orb-0077 | Oryza barthii | 58.29 | 1e-77 | 245 |
| LLPS-Orni-1021 | Oryza nivara | 58.29 | 1e-77 | 245 |
| LLPS-Orgl-0879 | Oryza glumaepatula | 58.29 | 1e-77 | 245 |
| LLPS-Ors-0513 | Oryza sativa | 58.29 | 1e-77 | 245 |
| LLPS-Brr-2743 | Brassica rapa | 58.29 | 6e-80 | 251 |
| LLPS-Orr-0252 | Oryza rufipogon | 58.29 | 1e-77 | 245 |
| LLPS-Org-0580 | Oryza glaberrima | 58.29 | 1e-77 | 245 |
| LLPS-Bro-0599 | Brassica oleracea | 58.29 | 3e-80 | 251 |
| LLPS-Eqc-2123 | Equus caballus | 58.22 | 5e-87 | 269 |
| LLPS-Cap-3175 | Cavia porcellus | 58.22 | 3e-86 | 267 |
| LLPS-Nol-4007 | Nomascus leucogenys | 58.18 | 4e-88 | 272 |
| LLPS-Xim-0690 | Xiphophorus maculatus | 58.1 | 7e-84 | 261 |
| LLPS-Osl-0221 | Ostreococcus lucimarinus | 58.06 | 7e-72 | 230 |
| LLPS-Tra-2488 | Triticum aestivum | 57.87 | 1e-76 | 242 |
| LLPS-Orbr-1883 | Oryza brachyantha | 57.87 | 6e-76 | 241 |
| LLPS-Mup-0248 | Mustela putorius furo | 57.75 | 9e-85 | 263 |
| LLPS-Chc-1063 | Chondrus crispus | 57.75 | 5e-64 | 208 |
| LLPS-Cea-0935 | Cercocebus atys | 57.73 | 2e-87 | 271 |
| LLPS-Chs-1931 | Chlorocebus sabaeus | 57.73 | 2e-87 | 270 |
| LLPS-Maf-2081 | Macaca fascicularis | 57.73 | 1e-87 | 270 |
| LLPS-Gog-1595 | Gorilla gorilla | 57.73 | 2e-87 | 270 |
| LLPS-Gaa-0312 | Gasterosteus aculeatus | 57.73 | 2e-87 | 270 |
| LLPS-Dio-1985 | Dipodomys ordii | 57.73 | 6e-88 | 271 |
| LLPS-Paa-4319 | Papio anubis | 57.73 | 2e-87 | 271 |
| LLPS-Mal-1177 | Mandrillus leucophaeus | 57.73 | 2e-87 | 270 |
| LLPS-Pap-3346 | Pan paniscus | 57.73 | 1e-87 | 270 |
| LLPS-Pat-2561 | Pan troglodytes | 57.73 | 1e-87 | 270 |
| LLPS-Hos-0656 | Homo sapiens | 57.73 | 2e-87 | 270 |
| LLPS-Orc-0029 | Oryctolagus cuniculus | 57.73 | 8e-88 | 271 |
| LLPS-Mam-0615 | Macaca mulatta | 57.73 | 2e-87 | 271 |
| LLPS-Poa-2939 | Pongo abelii | 57.73 | 2e-87 | 270 |
| LLPS-Myl-1326 | Myotis lucifugus | 57.53 | 5e-87 | 269 |
| LLPS-Tru-0420 | Triticum urartu | 57.51 | 9e-73 | 233 |
| LLPS-Brd-1286 | Brachypodium distachyon | 57.36 | 1e-76 | 242 |
| LLPS-Xet-2166 | Xenopus tropicalis | 57.34 | 4e-86 | 266 |
| LLPS-Amt-1607 | Amborella trichopoda | 57.29 | 2e-75 | 239 |
| LLPS-Dar-2427 | Danio rerio | 57.28 | 2e-85 | 265 |
| LLPS-Mum-3370 | Mus musculus | 57.27 | 5e-88 | 271 |
| LLPS-Fud-1820 | Fukomys damarensis | 57.27 | 3e-87 | 270 |
| LLPS-Man-0088 | Macaca nemestrina | 57.27 | 4e-87 | 269 |
| LLPS-Gag-1143 | Gaeumannomyces graminis | 57.25 | 2e-103 | 312 |
| LLPS-Ova-0681 | Ovis aries | 57.14 | 2e-79 | 249 |
| LLPS-Bot-3815 | Bos taurus | 57.08 | 3e-86 | 267 |
| LLPS-Aim-3342 | Ailuropoda melanoleuca | 57.08 | 1e-86 | 268 |
| LLPS-Fec-1439 | Felis catus | 57.08 | 3e-86 | 267 |
| LLPS-Urm-2137 | Ursus maritimus | 57.08 | 8e-87 | 268 |
| LLPS-Caf-1162 | Canis familiaris | 57.08 | 3e-86 | 267 |
| LLPS-Zem-1836 | Zea mays | 57.08 | 6e-80 | 251 |
| LLPS-Cus-0610 | Cucumis sativus | 57.0 | 6e-76 | 241 |
| LLPS-Icp-2830 | Ictalurus punctatus | 56.96 | 1e-85 | 265 |
| LLPS-Sob-1462 | Sorghum bicolor | 56.87 | 7e-79 | 248 |
| LLPS-Aon-1751 | Aotus nancymaae | 56.82 | 8e-87 | 268 |
| LLPS-Caj-3609 | Callithrix jacchus | 56.82 | 1e-86 | 268 |
| LLPS-Ran-2593 | Rattus norvegicus | 56.82 | 4e-87 | 269 |
| LLPS-Otg-4610 | Otolemur garnettii | 56.82 | 4e-87 | 269 |
| LLPS-Ict-3594 | Ictidomys tridecemlineatus | 56.82 | 6e-87 | 268 |
| LLPS-Gas-0935 | Galdieria sulphuraria | 56.8 | 3e-90 | 278 |
| LLPS-Sol-1626 | Solanum lycopersicum | 56.78 | 4e-76 | 241 |
| LLPS-Glm-1627 | Glycine max | 56.78 | 2e-74 | 237 |
| LLPS-Met-1477 | Medicago truncatula | 56.78 | 5e-75 | 238 |
| LLPS-Mod-2951 | Monodelphis domestica | 56.71 | 1e-87 | 271 |
| LLPS-Sem-1976 | Selaginella moellendorffii | 56.59 | 1e-73 | 234 |
| LLPS-Cae-1365 | Caenorhabditis elegans | 56.44 | 5e-83 | 259 |
| LLPS-Ten-1852 | Tetraodon nigroviridis | 56.36 | 9e-86 | 266 |
| LLPS-Cas-0912 | Carlito syrichta | 56.36 | 2e-86 | 267 |
| LLPS-Loa-1137 | Loxodonta africana | 56.33 | 4e-89 | 275 |
| LLPS-Viv-1785 | Vitis vinifera | 56.28 | 1e-74 | 238 |
| LLPS-Phv-1102 | Phaseolus vulgaris | 56.28 | 1e-74 | 237 |
| LLPS-Chr-1589 | Chlamydomonas reinhardtii | 56.16 | 3e-79 | 249 |
| LLPS-Ere-0880 | Erinaceus europaeus | 56.0 | 3e-86 | 267 |
| LLPS-Cym-0813 | Cyanidioschyzon merolae | 55.88 | 4e-75 | 239 |
| LLPS-Rhb-3620 | Rhinopithecus bieti | 55.61 | 6e-80 | 251 |
| LLPS-Lac-3641 | Latimeria chalumnae | 55.56 | 4e-75 | 238 |
| LLPS-Mao-0306 | Magnaporthe oryzae | 55.51 | 4e-102 | 309 |
| LLPS-Vir-0508 | Vigna radiata | 55.26 | 2e-66 | 214 |
| LLPS-Asm-0168 | Astyanax mexicanus | 55.22 | 1e-82 | 258 |
| LLPS-Mua-1517 | Musa acuminata | 55.19 | 6e-77 | 243 |
| LLPS-Arl-1016 | Arabidopsis lyrata | 55.19 | 1e-79 | 250 |
| LLPS-Cii-0778 | Ciona intestinalis | 55.09 | 1e-80 | 252 |
| LLPS-Art-2486 | Arabidopsis thaliana | 54.72 | 2e-78 | 247 |
| LLPS-Anc-2421 | Anolis carolinensis | 54.3 | 7e-52 | 175 |
| LLPS-Thc-2053 | Theobroma cacao | 54.21 | 9e-75 | 238 |
| LLPS-Cis-0678 | Ciona savignyi | 52.69 | 3e-59 | 197 |
| LLPS-Php-2000 | Physcomitrella patens | 52.04 | 5e-77 | 243 |
| LLPS-Via-1422 | Vigna angularis | 49.35 | 3e-68 | 222 |
| LLPS-Hov-1716 | Hordeum vulgare | 46.76 | 7e-78 | 248 |
| LLPS-Mea-3170 | Mesocricetus auratus | 45.31 | 3e-49 | 171 |
| LLPS-Orn-3711 | Oreochromis niloticus | 41.74 | 1e-44 | 159 |