• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Poa-0297
CSNK2B

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Casein kinase II subunit beta
Gene Name: CSNK2B
Ensembl Gene: ENSPPYG00000016448.2
Ensembl Protein: ENSPPYP00000018392.2
Organism: Pongo abelii
Taxa ID: 9601
LLPS Type: LLPS regulator


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nucleolus, PML nuclear body, Balbiani bodyPredicted from orthologs(View)

▼ FUNCTION


Plays a complex role in regulating the basal catalytic activity of the alpha subunit.

▼ SEQUENCE


Protein Sequence (FASTA)
1     MSSSEEVSWI  SWFCGLRGNE  FFCEVDEDYI  QDKFNLTGLN  EQVPHYRQAL  DMILDLEPDE  60
61    ELEDNPNQSD  LIEQAAEMLY  GLIHARYILT  NRGIAQMLEK  YQQGDFGYCP  RVYCENQPML  120
121   PIGLSDIPGE  AMVKLYCPKC  MDVYTPKSSR  HHHTDGAYFG  TGFPHMLFMV  HPEYRPKRPA  180
181   NQFVPRLYGF  KIHPMAYQLQ  LQAASNFKSP  VKTIR  215
Nucleotide CDS Sequence (FASTA)
1     ATGAGCAGCT  CAGAGGAGGT  GTCCTGGATT  TCCTGGTTTT  GTGGGCTCCG  TGGCAATGAA  60
61    TTCTTCTGTG  AAGTGGATGA  AGACTACATC  CAGGACAAAT  TTAATCTTAC  TGGACTCAAT  120
121   GAGCAGGTCC  CTCACTATCG  ACAAGCTCTA  GACATGATCT  TGGACCTGGA  GCCTGATGAA  180
181   GAACTGGAAG  ACAACCCCAA  CCAGAGTGAC  CTGATTGAGC  AGGCAGCCGA  GATGCTTTAT  240
241   GGATTGATCC  ACGCCCGCTA  CATCCTTACC  AACCGTGGCA  TCGCCCAGAT  GTTGGAAAAG  300
301   TACCAGCAAG  GAGACTTTGG  TTACTGTCCT  CGTGTGTACT  GTGAGAACCA  GCCAATGCTT  360
361   CCCATTGGCC  TTTCAGACAT  CCCAGGTGAA  GCCATGGTGA  AGCTCTACTG  CCCCAAGTGC  420
421   ATGGATGTGT  ACACACCCAA  GTCATCAAGA  CACCATCACA  CGGATGGCGC  CTACTTCGGC  480
481   ACTGGTTTCC  CTCACATGCT  CTTCATGGTG  CATCCCGAGT  ACCGGCCCAA  GAGACCTGCC  540
541   AACCAGTTTG  TGCCCAGGCT  CTACGGTTTC  AAGATCCATC  CGATGGCCTA  CCAGCTGCAG  600
601   CTCCAAGCCG  CCAGCAACTT  CAAGAGCCCA  GTCAAGACGA  TTCGCTGA  648

▼ KEYWORD


ID
Family
Complete proteome
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
PcG protein complex
Cellular Component
Plasma membrane
Cellular Component
Protein kinase CK2 complex
Molecular Function
Chromatin binding
Molecular Function
Identical protein binding
Molecular Function
Protein domain specific binding
Molecular Function
Protein kinase regulator activity
Molecular Function
Protein serine/threonine kinase activity
Molecular Function
Signaling receptor binding
Molecular Function
Transcription factor binding
Biological Process
Adiponectin-activated signaling pathway
Biological Process
Endothelial tube morphogenesis
Biological Process
Negative regulation of blood vessel endothelial cell migration
Biological Process
Peptidyl-threonine phosphorylation
Biological Process
Positive regulation of activin receptor signaling pathway
Biological Process
Positive regulation of pathway-restricted SMAD protein phosphorylation

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Dio-2339Dipodomys ordii100.01e-148 420
LLPS-Bot-0043Bos taurus100.01e-148 420
LLPS-Mal-1916Mandrillus leucophaeus100.04e-70 223
LLPS-Paa-0909Papio anubis100.04e-70 223
LLPS-Ova-1294Ovis aries100.03e-149 422
LLPS-Myl-0924Myotis lucifugus100.04e-149 422
LLPS-Aim-2801Ailuropoda melanoleuca100.02e-149 422
LLPS-Mup-3142Mustela putorius furo100.01e-148 420
LLPS-Ran-1994Rattus norvegicus100.01e-148 420
LLPS-Aon-1344Aotus nancymaae100.04e-149 421
LLPS-Cea-2703Cercocebus atys100.04e-70 223
LLPS-Sah-1271Sarcophilus harrisii100.03e-149 422
LLPS-Maf-1038Macaca fascicularis100.04e-70 223
LLPS-Mea-1144Mesocricetus auratus100.01e-148 420
LLPS-Chs-1992Chlorocebus sabaeus100.05e-124 357
LLPS-Caj-0659Callithrix jacchus100.04e-149 421
LLPS-Gog-1496Gorilla gorilla100.02e-70 223
LLPS-Mam-0475Macaca mulatta100.04e-70 223
LLPS-Anc-3113Anolis carolinensis100.03e-148 419
LLPS-Ict-0597Ictidomys tridecemlineatus100.06e-72 226
LLPS-Cas-1491Carlito syrichta100.03e-149 422
LLPS-Gaga-1273Gallus gallus100.02e-1263.9
LLPS-Man-1942Macaca nemestrina100.04e-70 223
LLPS-Loa-4069Loxodonta africana100.04e-149 422
LLPS-Hos-3167Homo sapiens100.05e-149 421
LLPS-Pap-2408Pan paniscus100.02e-70 223
LLPS-Urm-0591Ursus maritimus100.07e-148 419
LLPS-Pat-3436Pan troglodytes100.03e-70 223
LLPS-Fec-1105Felis catus100.07e-149 421
LLPS-Mod-1103Monodelphis domestica100.05e-149 421
LLPS-Lac-1794Latimeria chalumnae100.03e-73 225
LLPS-Orc-0011Oryctolagus cuniculus100.01e-148 420
LLPS-Rhb-0880Rhinopithecus bieti100.04e-70 223
LLPS-Otg-0419Otolemur garnettii100.01e-148 420
LLPS-Gaa-1381Gasterosteus aculeatus99.537e-148 417
LLPS-Orl-2477Oryzias latipes99.536e-148 418
LLPS-Scm-0017Scophthalmus maximus99.535e-149 425
LLPS-Xet-1175Xenopus tropicalis99.481e-127 365
LLPS-Caf-1335Canis familiaris99.477e-126 365
LLPS-Sus-2440Sus scrofa99.192e-70 223
LLPS-Eqc-1200Equus caballus99.191e-70 224
LLPS-Scf-0973Scleropages formosus99.073e-147 416
LLPS-Xim-0324Xiphophorus maculatus99.073e-147 416
LLPS-Asm-2490Astyanax mexicanus99.074e-148 420
LLPS-Icp-1099Ictalurus punctatus99.073e-147 416
LLPS-Dar-0003Danio rerio99.073e-147 416
LLPS-Pof-2039Poecilia formosa99.073e-147 416
LLPS-Orn-2534Oreochromis niloticus99.073e-147 416
LLPS-Leo-1838Lepisosteus oculatus98.689e-109 316
LLPS-Tar-2952Takifugu rubripes98.146e-145 410
LLPS-Mum-2470Mus musculus97.674e-72 226
LLPS-Cap-2211Cavia porcellus96.887e-72 225
LLPS-Ten-0144Tetraodon nigroviridis95.814e-141 400
LLPS-Pes-0539Pelodiscus sinensis95.433e-138 393
LLPS-Fud-1642Fukomys damarensis95.292e-125 360
LLPS-Nol-0197Nomascus leucogenys92.565e-132 378
LLPS-Cii-0578Ciona intestinalis91.048e-134 382
LLPS-Cis-0533Ciona savignyi89.154e-129 370
LLPS-Drm-0476Drosophila melanogaster88.377e-134 383
LLPS-Cae-1351Caenorhabditis elegans81.01e-113 332
LLPS-Sot-0721Solanum tuberosum63.951e-59 196
LLPS-Sei-2488Setaria italica63.953e-58 192
LLPS-Via-0095Vigna angularis63.271e-59 194
LLPS-Met-1186Medicago truncatula63.271e-59 196
LLPS-Mel-0528Melampsora laricipopulina61.995e-68 216
LLPS-Crn-0628Cryptococcus neoformans61.051e-68 218
LLPS-Sol-1181Solanum lycopersicum60.942e-80 248
LLPS-Mua-0157Musa acuminata60.422e-79 247
LLPS-Viv-1788Vitis vinifera60.266e-59 194
LLPS-Brn-1752Brassica napus60.113e-78 243
LLPS-Hov-0116Hordeum vulgare59.91e-79 246
LLPS-Brd-0809Brachypodium distachyon59.95e-79 245
LLPS-Chr-0492Chlamydomonas reinhardtii59.697e-78 242
LLPS-Spr-1076Sporisorium reilianum59.662e-68 221
LLPS-Lep-0486Leersia perrieri59.388e-78 242
LLPS-Orgl-0175Oryza glumaepatula59.384e-77 240
LLPS-Cus-1687Cucumis sativus59.383e-76 238
LLPS-Tra-2335Triticum aestivum59.387e-78 241
LLPS-Orb-1155Oryza barthii59.381e-77 239
LLPS-Ori-2369Oryza indica59.384e-77 240
LLPS-Orni-0228Oryza nivara59.386e-79 244
LLPS-Dac-1600Daucus carota59.387e-77 239
LLPS-Coc-1045Corchorus capsularis59.385e-78 242
LLPS-Orm-1873Oryza meridionalis59.382e-77 241
LLPS-Orr-1002Oryza rufipogon59.384e-77 240
LLPS-Org-1029Oryza glaberrima59.388e-79 244
LLPS-Orp-2264Oryza punctata59.384e-79 245
LLPS-Ors-2058Oryza sativa59.384e-77 240
LLPS-Sob-0770Sorghum bicolor59.383e-78 243
LLPS-Orbr-2280Oryza brachyantha59.384e-78 240
LLPS-Bro-0911Brassica oleracea59.265e-78 242
LLPS-Brr-1025Brassica rapa59.264e-78 242
LLPS-Sem-2119Selaginella moellendorffii59.185e-79 242
LLPS-Arl-1099Arabidopsis lyrata59.044e-75 234
LLPS-Glm-1737Glycine max58.857e-80 247
LLPS-Zem-0985Zea mays58.858e-77 239
LLPS-Phv-0807Phaseolus vulgaris58.855e-80 248
LLPS-Nia-0138Nicotiana attenuata58.769e-79 244
LLPS-Scp-0922Schizosaccharomyces pombe58.463e-76 236
LLPS-Thc-1120Theobroma cacao58.339e-77 239
LLPS-Art-2613Arabidopsis thaliana58.333e-76 238
LLPS-Gor-0581Gossypium raimondii58.335e-77 240
LLPS-Mae-1261Manihot esculenta58.338e-77 239
LLPS-Pot-1964Populus trichocarpa58.191e-67 216
LLPS-Php-0535Physcomitrella patens57.951e-78 244
LLPS-Prp-0407Prunus persica57.812e-76 238
LLPS-Scj-0397Schizosaccharomyces japonicus57.537e-72 225
LLPS-Amt-1690Amborella trichopoda57.292e-76 236
LLPS-Osl-0367Ostreococcus lucimarinus57.226e-69 217
LLPS-Hea-0040Helianthus annuus56.778e-77 239
LLPS-Cym-0512Cyanidioschyzon merolae56.062e-73 232
LLPS-Scc-0544Schizosaccharomyces cryophilus55.773e-75 234
LLPS-Usm-1169Ustilago maydis55.114e-60 198
LLPS-Tru-0435Triticum urartu53.656e-62 204
LLPS-Abg-0108Absidia glauca53.44e-77 238
LLPS-Asf-0184Aspergillus flavus53.337e-70 222
LLPS-Ved-0231Verticillium dahliae53.335e-38 138
LLPS-Tum-1506Tuber melanosporum53.195e-65 212
LLPS-Asn-1141Aspergillus nidulans52.582e-69 219
LLPS-Ast-0718Aspergillus terreus52.585e-69 219
LLPS-Pyt-0984Pyrenophora teres52.367e-61 207
LLPS-Lem-0642Leptosphaeria maculans52.319e-67 213
LLPS-Pytr-0902Pyrenophora triticirepentis52.311e-67 214
LLPS-Asni-0968Aspergillus niger52.063e-68 217
LLPS-Dos-0743Dothistroma septosporum52.065e-68 216
LLPS-Aso-0202Aspergillus oryzae51.941e-70 222
LLPS-Nec-0256Neurospora crassa51.552e-67 215
LLPS-Zyt-0633Zymoseptoria tritici51.556e-69 218
LLPS-Cog-0752Colletotrichum gloeosporioides51.556e-63 218
LLPS-Mao-0323Magnaporthe oryzae51.535e-69 219
LLPS-Phn-0190Phaeosphaeria nodorum51.311e-64 206
LLPS-Cogr-0621Colletotrichum graminicola51.287e-66 210
LLPS-Gas-1027Galdieria sulphuraria51.272e-69 219
LLPS-Asfu-1223Aspergillus fumigatus51.062e-62 203
LLPS-Nef-0893Neosartorya fischeri51.062e-62 203
LLPS-Blg-1204Blumeria graminis51.039e-67 213
LLPS-Trr-0082Trichoderma reesei51.035e-67 213
LLPS-Coo-0103Colletotrichum orbiculare50.524e-66 211
LLPS-Trv-0565Trichoderma virens50.528e-62 214
LLPS-Gag-0525Gaeumannomyces graminis50.514e-67 214
LLPS-Map-0282Magnaporthe poae50.512e-67 215
LLPS-Beb-0339Beauveria bassiana50.514e-67 213
LLPS-Fus-1051Fusarium solani50.514e-67 214
LLPS-Asc-0967Aspergillus clavatus50.254e-61 199
LLPS-Yal-0281Yarrowia lipolytica49.742e-61 200
LLPS-Put-0896Puccinia triticina48.77e-68 216
LLPS-Sac-1548Saccharomyces cerevisiae47.524e-58 191
LLPS-Miv-0382Microbotryum violaceum47.274e-65 208
LLPS-Pug-0139Puccinia graminis46.866e-68 216
LLPS-Kop-1199Komagataella pastoris46.77e-46 159
LLPS-Fuv-0323Fusarium verticillioides45.594e-48 167
LLPS-Fuo-0535Fusarium oxysporum45.594e-48 167
LLPS-Asg-0379Ashbya gossypii45.191e-60 197
LLPS-Ora-1118Ornithorhynchus anatinus43.82e-27 107