• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Asm-2490

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Casein kinase II subunit beta
Ensembl Gene: ENSAMXG00000011597.2
Ensembl Protein: ENSAMXP00000027372.1
Organism: Astyanax mexicanus
Taxa ID: 7994
LLPS Type: LLPS regulator


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nucleolus, PML nuclear body, Balbiani bodyPredicted from orthologs(View)

▼ FUNCTION


Plays a complex role in regulating the basal catalytic activity of the alpha subunit.

▼ SEQUENCE


Protein Sequence (FASTA)
1     MITVKMRVKR  MRRTAKKHES  TGNTTRQNTG  SELFLPSVLF  YLLLSSFPKM  SSSEEVSWIS  60
61    WFCGLRGNEF  FCEVDEDYIQ  DKFNLTGLNE  QVPHYRQALD  MILDLEPDEE  LEDNPNQSDL  120
121   IEQAAEMLYG  LIHARYILTN  RGIAQMLEKY  QQGDFGYCPR  VYCENQPMLP  IGLSDIPGEA  180
181   MVKLYCPKCM  DVYTPKSSRH  HHTDGAYFGT  GFPHMLFMVH  PEYRPKRPAN  QFVPRLYGFK  240
241   IHPMAYQLQL  QAASSFKSPV  KAIR  264
Nucleotide CDS Sequence (FASTA)
1     ATGAGCAGTT  CGGAGGAAGT  TTCGTGGATT  TCTTGGTTTT  GTGGTCTACG  AGGAAACGAG  60
61    TTCTTCTGTG  AGGTGGATGA  GGACTATATC  CAGGATAAGT  TTAACCTCAC  TGGACTCAAT  120
121   GAGCAGGTTC  CACATTACAG  ACAAGCTCTG  GACATGATTT  TGGATCTGGA  ACCTGATGAG  180
181   GAACTGGAAG  ACAACCCAAA  CCAGAGTGAC  CTGATAGAGC  AGGCTGCTGA  GATGCTCTAT  240
241   GGCCTGATTC  ATGCACGATA  CATTCTTACT  AATCGTGGCA  TTGCGCAGAT  GTTGGAGAAA  300
301   TACCAGCAGG  GAGACTTTGG  CTATTGCCCT  CGTGTTTACT  GTGAGAACCA  GCCAATGTTG  360
361   CCCATTGGTT  TGTCCGATAT  CCCTGGAGAA  GCTATGGTCA  AACTCTACTG  TCCTAAATGT  420
421   ATGGATGTGT  ACACACCGAA  GTCATCTAGG  CACCACCACA  CTGATGGGGC  CTACTTTGGA  480
481   ACAGGCTTTC  CCCATATGCT  CTTCATGGTT  CACCCTGAAT  ACCGGCCAAA  GAGGCCTGCA  540
541   AACCAGTTTG  TGCCCAGGCT  CTATGGCTTC  AAGATCCACC  CTATGGCATA  CCAGCTACAG  600
601   CTGCAGGCAG  CCTCTAGCTT  CAAGAGCCCT  GTCAAGGCCA  TCCGCTAA  648

▼ KEYWORD


ID
Family
Complete proteome
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Protein kinase CK2 complex
Molecular Function
Protein kinase regulator activity

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Xim-0324Xiphophorus maculatus100.03e-149 423
LLPS-Scf-0973Scleropages formosus100.03e-149 423
LLPS-Paa-0909Papio anubis100.02e-70 225
LLPS-Mal-1916Mandrillus leucophaeus100.02e-70 225
LLPS-Chs-1992Chlorocebus sabaeus100.01e-124 361
LLPS-Maf-1038Macaca fascicularis100.02e-70 225
LLPS-Leo-1838Lepisosteus oculatus100.03e-110 322
LLPS-Cea-2703Cercocebus atys100.02e-70 225
LLPS-Orl-1786Oryzias latipes100.03e-149 423
LLPS-Gog-1496Gorilla gorilla100.01e-70 226
LLPS-Icp-1099Ictalurus punctatus100.03e-149 423
LLPS-Mam-0475Macaca mulatta100.02e-70 225
LLPS-Ict-0597Ictidomys tridecemlineatus100.02e-72 229
LLPS-Lac-1794Latimeria chalumnae100.01e-73 228
LLPS-Dar-0003Danio rerio100.03e-149 423
LLPS-Pof-2039Poecilia formosa100.03e-149 423
LLPS-Pat-3436Pan troglodytes100.01e-70 226
LLPS-Pap-2408Pan paniscus100.09e-71 226
LLPS-Man-1942Macaca nemestrina100.02e-70 225
LLPS-Orn-1108Oreochromis niloticus100.03e-149 423
LLPS-Rhb-0880Rhinopithecus bieti100.02e-70 225
LLPS-Caf-1335Canis familiaris99.471e-126 369
LLPS-Sus-2440Sus scrofa99.199e-71 226
LLPS-Eqc-1200Equus caballus99.196e-71 227
LLPS-Tar-2952Takifugu rubripes99.078e-147 417
LLPS-Bot-0043Bos taurus99.075e-148 420
LLPS-Dio-2339Dipodomys ordii99.075e-148 420
LLPS-Gaa-1381Gasterosteus aculeatus99.073e-148 421
LLPS-Ran-1994Rattus norvegicus99.075e-148 420
LLPS-Aim-2801Ailuropoda melanoleuca99.073e-149 424
LLPS-Mup-3142Mustela putorius furo99.075e-148 420
LLPS-Ova-1294Ovis aries99.073e-149 424
LLPS-Myl-0924Myotis lucifugus99.073e-149 424
LLPS-Mea-1144Mesocricetus auratus99.075e-148 420
LLPS-Aon-1344Aotus nancymaae99.072e-149 424
LLPS-Sah-1271Sarcophilus harrisii99.073e-149 424
LLPS-Caj-0659Callithrix jacchus99.077e-149 423
LLPS-Poa-0297Pongo abelii99.075e-148 420
LLPS-Cas-1491Carlito syrichta99.073e-149 424
LLPS-Anc-3113Anolis carolinensis99.074e-148 421
LLPS-Fec-1105Felis catus99.075e-149 423
LLPS-Mod-1103Monodelphis domestica99.076e-149 422
LLPS-Scm-0017Scophthalmus maximus99.076e-150 429
LLPS-Hos-3167Homo sapiens99.073e-149 424
LLPS-Urm-0591Ursus maritimus99.077e-148 421
LLPS-Loa-4069Loxodonta africana99.074e-149 424
LLPS-Otg-0419Otolemur garnettii99.075e-148 420
LLPS-Orc-0011Oryctolagus cuniculus99.075e-148 420
LLPS-Xet-1175Xenopus tropicalis98.431e-126 365
LLPS-Mum-2470Mus musculus97.671e-72 229
LLPS-Ten-0144Tetraodon nigroviridis96.284e-142 405
LLPS-Pes-0539Pelodiscus sinensis94.523e-137 393
LLPS-Fud-1642Fukomys damarensis94.241e-124 359
LLPS-Gaga-1273Gallus gallus93.331e-1060.1
LLPS-Nol-0197Nomascus leucogenys91.677e-132 379
LLPS-Cii-0578Ciona intestinalis91.044e-134 385
LLPS-Cap-2211Cavia porcellus90.072e-72 228
LLPS-Cis-0533Ciona savignyi89.152e-129 373
LLPS-Drm-0476Drosophila melanogaster88.374e-134 385
LLPS-Cae-1351Caenorhabditis elegans81.06e-114 334
LLPS-Sot-0721Solanum tuberosum63.956e-60 199
LLPS-Sei-2488Setaria italica63.952e-58 194
LLPS-Via-0095Vigna angularis63.276e-60 197
LLPS-Mel-0528Melampsora laricipopulina61.995e-68 218
LLPS-Crn-0628Cryptococcus neoformans61.052e-68 219
LLPS-Sol-1181Solanum lycopersicum60.941e-80 251
LLPS-Scp-0922Schizosaccharomyces pombe60.753e-76 238
LLPS-Mua-0157Musa acuminata60.421e-79 250
LLPS-Viv-1788Vitis vinifera60.264e-59 196
LLPS-Brn-1752Brassica napus60.111e-78 246
LLPS-Brd-0809Brachypodium distachyon59.92e-79 248
LLPS-Met-0476Medicago truncatula59.94e-80 249
LLPS-Hov-0116Hordeum vulgare59.95e-80 249
LLPS-Chr-0492Chlamydomonas reinhardtii59.693e-78 245
LLPS-Spr-1076Sporisorium reilianum59.662e-68 223
LLPS-Orgl-0175Oryza glumaepatula59.382e-77 243
LLPS-Lep-0486Leersia perrieri59.385e-78 244
LLPS-Tra-2335Triticum aestivum59.383e-78 244
LLPS-Cus-1687Cucumis sativus59.381e-76 241
LLPS-Ori-2369Oryza indica59.382e-77 243
LLPS-Orb-1155Oryza barthii59.381e-77 241
LLPS-Dac-1600Daucus carota59.382e-77 243
LLPS-Orni-0683Oryza nivara59.382e-77 243
LLPS-Coc-1045Corchorus capsularis59.381e-78 246
LLPS-Orm-1873Oryza meridionalis59.389e-78 243
LLPS-Orr-1002Oryza rufipogon59.382e-77 243
LLPS-Org-2247Oryza glaberrima59.381e-76 241
LLPS-Ors-2058Oryza sativa59.382e-77 243
LLPS-Orp-1492Oryza punctata59.384e-78 244
LLPS-Sob-0770Sorghum bicolor59.381e-78 245
LLPS-Orbr-2280Oryza brachyantha59.383e-78 243
LLPS-Bro-0911Brassica oleracea59.262e-78 245
LLPS-Brr-1025Brassica rapa59.262e-78 245
LLPS-Sem-2119Selaginella moellendorffii59.185e-79 244
LLPS-Arl-1099Arabidopsis lyrata59.041e-75 238
LLPS-Glm-1737Glycine max58.852e-80 251
LLPS-Zem-0985Zea mays58.854e-77 241
LLPS-Phv-0807Phaseolus vulgaris58.852e-80 251
LLPS-Nia-0138Nicotiana attenuata58.765e-79 247
LLPS-Scc-0544Schizosaccharomyces cryophilus58.736e-75 234
LLPS-Thc-1120Theobroma cacao58.333e-77 242
LLPS-Gor-0581Gossypium raimondii58.332e-77 243
LLPS-Art-2613Arabidopsis thaliana58.331e-76 241
LLPS-Mae-1261Manihot esculenta58.333e-77 242
LLPS-Pot-1964Populus trichocarpa58.198e-68 218
LLPS-Php-0535Physcomitrella patens57.958e-79 247
LLPS-Prp-0407Prunus persica57.811e-76 241
LLPS-Scj-0397Schizosaccharomyces japonicus57.538e-72 227
LLPS-Amt-1690Amborella trichopoda57.292e-76 238
LLPS-Osl-0367Ostreococcus lucimarinus57.229e-69 218
LLPS-Hea-0040Helianthus annuus56.774e-77 241
LLPS-Cym-0512Cyanidioschyzon merolae55.781e-73 234
LLPS-Usm-0397Ustilago maydis54.842e-67 221
LLPS-Aso-0202Aspergillus oryzae54.792e-70 223
LLPS-Tru-0435Triticum urartu53.652e-62 207
LLPS-Abg-0108Absidia glauca53.47e-77 239
LLPS-Asf-0184Aspergillus flavus53.331e-69 223
LLPS-Ved-0231Verticillium dahliae53.339e-38 139
LLPS-Tum-1506Tuber melanosporum53.196e-65 214
LLPS-Asn-1141Aspergillus nidulans52.586e-69 220
LLPS-Pyt-0984Pyrenophora teres52.362e-60 208
LLPS-Lem-0642Leptosphaeria maculans52.312e-66 214
LLPS-Pytr-0902Pyrenophora triticirepentis52.313e-67 216
LLPS-Dos-0743Dothistroma septosporum52.061e-67 217
LLPS-Zyt-0633Zymoseptoria tritici51.551e-68 219
LLPS-Nec-0256Neurospora crassa51.555e-67 216
LLPS-Cog-0752Colletotrichum gloeosporioides51.551e-62 219
LLPS-Mao-0323Magnaporthe oryzae51.539e-69 220
LLPS-Cogr-0621Colletotrichum graminicola51.289e-66 212
LLPS-Gas-1027Galdieria sulphuraria51.275e-69 220
LLPS-Asfu-1223Aspergillus fumigatus51.065e-62 203
LLPS-Nef-0893Neosartorya fischeri51.064e-62 204
LLPS-Blg-1204Blumeria graminis51.032e-66 214
LLPS-Trr-0082Trichoderma reesei51.031e-66 214
LLPS-Asni-0968Aspergillus niger50.734e-68 218
LLPS-Ast-0718Aspergillus terreus50.738e-69 220
LLPS-Coo-0103Colletotrichum orbiculare50.528e-66 212
LLPS-Trv-0565Trichoderma virens50.521e-61 216
LLPS-Gag-0525Gaeumannomyces graminis50.511e-66 215
LLPS-Map-0282Magnaporthe poae50.515e-67 216
LLPS-Beb-0339Beauveria bassiana50.517e-67 214
LLPS-Fus-1051Fusarium solani50.519e-67 214
LLPS-Asc-0967Aspergillus clavatus50.251e-61 202
LLPS-Yal-0281Yarrowia lipolytica49.742e-61 201
LLPS-Phn-0190Phaeosphaeria nodorum48.781e-64 209
LLPS-Put-0896Puccinia triticina48.71e-67 217
LLPS-Miv-0382Microbotryum violaceum48.185e-65 210
LLPS-Sac-1548Saccharomyces cerevisiae47.526e-58 192
LLPS-Pug-0139Puccinia graminis46.862e-67 217
LLPS-Kop-1199Komagataella pastoris46.78e-46 160
LLPS-Fuv-0323Fusarium verticillioides45.594e-48 169
LLPS-Fuo-0535Fusarium oxysporum45.594e-48 169
LLPS-Asg-0379Ashbya gossypii45.193e-60 197
LLPS-Ora-1118Ornithorhynchus anatinus44.632e-27 108