• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Php-0588
PHYPA_027572

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Peptidyl-prolyl cis-trans isomerase
Gene Name: PHYPA_027572
Ensembl Gene: Pp3c23_2850
Ensembl Protein: Pp3c23_2850V3.7
Organism: Physcomitrella patens
Taxa ID: 3218
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
LLPS-Drm-0080@Drosophila melanogaster@Q9W227@Others@Stress granule@61.33@2e-71@226N/A

▼ FUNCTION


PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

▼ SEQUENCE


Protein Sequence (FASTA)
Nucleotide CDS Sequence (FASTA)
1     ATGAATCTTC  TCGTTCCTGA  TTCGTTAGGA  GCCCCGAGCA  ATGTGGTGTC  GCAAGTTTCT  60
61    TCTCTAAGGA  CCAGTGTGGA  AACGAGTGCG  AGCTCTGTGA  GCCCTGTGGT  TATACGTGGC  120
121   AGGAGACATG  CGACCTTAGG  ATTGTCACAC  AGTGGCTTCG  GAGCCACCTT  CCAGCAATCG  180
181   TGCACACATT  CGGCATCAAA  TATGTGCAGG  AATCAGGTCA  ACGTCAGGGC  GGCACAGGTG  240
241   CCCTCAGAAG  TGACGACTCA  AGATAAGGTG  ACTAAGAAAT  GCTTTTTCGA  CATCGAAATT  300
301   GACGACAAGC  CGTGTGGTCG  CATCATTTTT  GGGCTCTTCG  GTGACACAGT  CCCTGATACC  360
361   GTCGAAAACT  TCCGTTGTCT  TTGCACAGGT  GAGAGGCGTT  TTGGTTACAA  GGGATCGGCG  420
421   TTCCACCGTG  TAATCAAAGA  CTTTATGATC  CAGGGTGGTG  ATTTTGACCA  AGGCAATGGC  480
481   ACTGGTGGAT  ATAGTATTTA  CGGCAATACC  TTTAAGGATG  AGAACTTCAA  ATTGAGGCAT  540
541   ACTGGAGAGG  GAGTTTTGAG  CATGGCAAAT  CGTGGGCCTG  ATACTAATGG  AAGCCAGTTT  600
601   TTCATCTGTA  CTGCAGAGAC  CTCATGGCTA  GATGGCCGTC  ATGTTGTATT  TGGACAAGTG  660
661   ATTGAAGGTA  TGGATGTAGT  GAAGGCAATT  GAAGGGCAAG  ATGTTGACCC  TAACGATAGA  720
721   CCCATGAAGA  AGTGTGTTAT  TGTTGAGAGT  GGTGAATTGT  AG  762

▼ KEYWORD


ID
Family
Complete proteome
Isomerase
Reference proteome
Rotamase

▼ GENE ONTOLOGY


ID
Classification
Description
Molecular Function
Peptidyl-prolyl cis-trans isomerase activity
Molecular Function
Protein folding

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Amt-0172Amborella trichopoda72.226e-74 232
LLPS-Orp-1471Oryza punctata71.595e-75 235
LLPS-Viv-0670Vitis vinifera71.262e-72 229
LLPS-Brn-1922Brassica napus71.181e-71 227
LLPS-Brr-1719Brassica rapa71.189e-72 227
LLPS-Hea-0660Helianthus annuus71.041e-73 231
LLPS-Dac-1320Daucus carota70.883e-71 231
LLPS-Sol-1671Solanum lycopersicum70.02e-69 220
LLPS-Orl-0008Oryzias latipes69.781e-57 187
LLPS-Lep-0403Leersia perrieri69.445e-74 233
LLPS-Prp-0394Prunus persica69.42e-73 231
LLPS-Sot-1150Solanum tuberosum69.367e-69 219
LLPS-Mao-0281Magnaporthe oryzae69.092e-69 219
LLPS-Orbr-0936Oryza brachyantha68.893e-74 233
LLPS-Nia-0534Nicotiana attenuata68.851e-71 226
LLPS-Art-2194Arabidopsis thaliana68.681e-72 229
LLPS-Glm-1023Glycine max68.248e-71 224
LLPS-Mae-0912Manihot esculenta68.132e-71 226
LLPS-Gor-1345Gossypium raimondii68.131e-70 224
LLPS-Sei-0570Setaria italica67.655e-71 224
LLPS-Scf-1161Scleropages formosus67.273e-64 206
LLPS-Osl-0446Ostreococcus lucimarinus67.278e-65 207
LLPS-Miv-0079Microbotryum violaceum67.272e-64 206
LLPS-Eqc-1894Equus caballus67.071e-63 204
LLPS-Sob-1549Sorghum bicolor67.076e-70 222
LLPS-Orc-1727Oryctolagus cuniculus67.072e-64 207
LLPS-Tra-0980Triticum aestivum67.016e-77 240
LLPS-Tru-0418Triticum urartu66.845e-75 235
LLPS-Asni-0113Aspergillus niger66.673e-64 208
LLPS-Asn-1099Aspergillus nidulans66.675e-65 208
LLPS-Coc-0576Corchorus capsularis66.671e-74 234
LLPS-Trr-0248Trichoderma reesei66.285e-69 218
LLPS-Ten-0793Tetraodon nigroviridis66.261e-61 200
LLPS-Met-1797Medicago truncatula66.156e-72 227
LLPS-Thc-0674Theobroma cacao66.091e-70 224
LLPS-Asfu-0365Aspergillus fumigatus66.062e-64 206
LLPS-Beb-0820Beauveria bassiana66.062e-67 214
LLPS-Org-0878Oryza glaberrima66.014e-76 238
LLPS-Orm-0428Oryza meridionalis66.018e-76 237
LLPS-Hov-1158Hordeum vulgare65.991e-73 233
LLPS-Chr-1108Chlamydomonas reinhardtii65.852e-65 208
LLPS-Brd-1141Brachypodium distachyon65.82e-73 231
LLPS-Sem-1722Selaginella moellendorffii65.785e-74 232
LLPS-Orgl-0115Oryza glumaepatula65.524e-76 238
LLPS-Orni-1471Oryza nivara65.524e-76 238
LLPS-Ori-0875Oryza indica65.524e-76 238
LLPS-Orb-1009Oryza barthii65.524e-76 238
LLPS-Orr-0141Oryza rufipogon65.524e-76 238
LLPS-Ors-1785Oryza sativa65.524e-76 238
LLPS-Drm-0080Drosophila melanogaster65.452e-61 199
LLPS-Icp-0124Ictalurus punctatus65.452e-64 207
LLPS-Asc-0176Aspergillus clavatus65.454e-64 206
LLPS-Orn-1516Oreochromis niloticus65.457e-62 200
LLPS-Lac-2284Latimeria chalumnae65.415e-59 192
LLPS-Bro-1086Brassica oleracea65.285e-72 228
LLPS-Nol-4125Nomascus leucogenys65.243e-63 204
LLPS-Trv-0867Trichoderma virens65.125e-68 218
LLPS-Tar-1918Takifugu rubripes65.032e-59 194
LLPS-Ere-0526Erinaceus europaeus65.04e-60 194
LLPS-Ran-0437Rattus norvegicus64.858e-64 205
LLPS-Mea-1016Mesocricetus auratus64.855e-64 206
LLPS-Mum-0639Mus musculus64.857e-65 208
LLPS-Anc-0740Anolis carolinensis64.788e-58 189
LLPS-Cus-1207Cucumis sativus64.675e-70 222
LLPS-Abg-1657Absidia glauca64.633e-59 195
LLPS-Xim-0806Xiphophorus maculatus64.69e-60 193
LLPS-Cii-0915Ciona intestinalis64.62e-57 187
LLPS-Pes-1052Pelodiscus sinensis64.68e-62 199
LLPS-Dar-2822Danio rerio64.152e-55 183
LLPS-Cis-0544Ciona savignyi64.077e-59 192
LLPS-Spr-0473Sporisorium reilianum64.076e-65 208
LLPS-Xet-0495Xenopus tropicalis63.984e-57 187
LLPS-Caf-3165Canis familiaris63.982e-60 196
LLPS-Pof-0486Poecilia formosa63.981e-59 192
LLPS-Dos-0440Dothistroma septosporum63.959e-64 205
LLPS-Cogr-1295Colletotrichum graminicola63.955e-66 211
LLPS-Gaga-0501Gallus gallus63.521e-55 184
LLPS-Tag-0742Taeniopygia guttata63.521e-56 186
LLPS-Pytr-0447Pyrenophora triticirepentis63.411e-59 194
LLPS-Nec-0156Neurospora crassa63.373e-64 209
LLPS-Pyt-0239Pyrenophora teres63.373e-61 201
LLPS-Fuv-0142Fusarium verticillioides63.374e-65 209
LLPS-Ved-0524Verticillium dahliae63.373e-68 216
LLPS-Fia-0545Ficedula albicollis63.352e-59 194
LLPS-Paa-0312Papio anubis63.031e-61 200
LLPS-Mal-0201Mandrillus leucophaeus63.031e-61 200
LLPS-Gog-2899Gorilla gorilla63.031e-61 200
LLPS-Fud-2014Fukomys damarensis63.033e-62 201
LLPS-Maf-0916Macaca fascicularis63.031e-61 200
LLPS-Cea-0842Cercocebus atys63.031e-61 200
LLPS-Poa-0314Pongo abelii63.031e-61 200
LLPS-Mam-0097Macaca mulatta63.031e-61 200
LLPS-Rhb-2617Rhinopithecus bieti63.031e-61 200
LLPS-Hos-1474Homo sapiens63.031e-61 200
LLPS-Man-0745Macaca nemestrina63.031e-61 200
LLPS-Coo-0029Colletotrichum orbiculare62.792e-65 211
LLPS-Fuo-0689Fusarium oxysporum62.795e-65 209
LLPS-Cog-0486Colletotrichum gloeosporioides62.794e-65 210
LLPS-Chc-0337Chondrus crispus62.735e-56 183
LLPS-Ova-1363Ovis aries62.423e-60 196
LLPS-Bot-0109Bos taurus62.424e-60 196
LLPS-Cae-1813Caenorhabditis elegans62.429e-58 189
LLPS-Caj-0187Callithrix jacchus62.422e-61 199
LLPS-Ora-0696Ornithorhynchus anatinus62.425e-60 196
LLPS-Aon-1503Aotus nancymaae62.422e-61 199
LLPS-Cap-0334Cavia porcellus62.423e-61 199
LLPS-Otg-0284Otolemur garnettii62.421e-61 199
LLPS-Map-0157Magnaporthe poae62.372e-64 206
LLPS-Crn-0500Cryptococcus neoformans62.353e-59 197
LLPS-Via-0309Vigna angularis62.323e-70 223
LLPS-Sus-0323Sus scrofa62.261e-55 184
LLPS-Asm-0622Astyanax mexicanus62.154e-62 201
LLPS-Sah-0750Sarcophilus harrisii62.113e-58 189
LLPS-Tut-0947Tursiops truncatus61.882e-63 204
LLPS-Mup-0614Mustela putorius furo61.827e-60 195
LLPS-Aim-2390Ailuropoda melanoleuca61.821e-59 194
LLPS-Myl-2435Myotis lucifugus61.826e-60 195
LLPS-Fec-1924Felis catus61.822e-59 194
LLPS-Pat-4900Pan troglodytes61.593e-56 184
LLPS-Pap-3143Pan paniscus61.593e-56 184
LLPS-Cas-0022Carlito syrichta61.355e-59 192
LLPS-Phn-0241Phaeosphaeria nodorum61.313e-56 184
LLPS-Vir-0720Vigna radiata61.279e-58 190
LLPS-Mua-0819Musa acuminata61.217e-74 232
LLPS-Gaa-1762Gasterosteus aculeatus61.082e-59 194
LLPS-Fus-0079Fusarium solani61.051e-61 199
LLPS-Aso-0029Aspergillus oryzae60.994e-64 205
LLPS-Loa-0074Loxodonta africana60.926e-61 197
LLPS-Arl-0543Arabidopsis lyrata60.872e-59 194
LLPS-Zem-0760Zea mays60.878e-78 242
LLPS-Pot-1560Populus trichocarpa60.873e-68 218
LLPS-Scj-0218Schizosaccharomyces japonicus60.612e-58 191
LLPS-Phv-1358Phaseolus vulgaris60.586e-70 223
LLPS-Scs-0057Sclerotinia sclerotiorum60.472e-58 194
LLPS-Leo-0202Lepisosteus oculatus60.452e-61 199
LLPS-Dio-1234Dipodomys ordii60.344e-61 198
LLPS-Chs-0554Chlorocebus sabaeus60.344e-61 198
LLPS-Ict-0460Ictidomys tridecemlineatus60.342e-61 199
LLPS-Mod-1772Monodelphis domestica60.343e-60 196
LLPS-Urm-0027Ursus maritimus60.122e-60 197
LLPS-Usm-0289Ustilago maydis60.05e-60 195
LLPS-Zyt-0030Zymoseptoria tritici59.443e-59 192
LLPS-Scp-0530Schizosaccharomyces pombe59.393e-57 188
LLPS-Gag-0423Gaeumannomyces graminis58.915e-64 205
LLPS-Ast-0094Aspergillus terreus58.011e-55 184
LLPS-Yal-0625Yarrowia lipolytica57.81e-55 184
LLPS-Mel-0792Melampsora laricipopulina57.785e-56 185