• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pes-2762
RBFOX1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: RNA binding protein fox-1 homolog
Gene Name: RBFOX1
Ensembl Gene: ENSPSIG00000006523.1
Ensembl Protein: ENSPSIP00000007059.1
Organism: Pelodiscus sinensis
Taxa ID: 13735
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, Stress granulePredicted from orthologs(View)

▼ FUNCTION

RNA-binding protein that regulates alternative splicing events.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEDKGSRMVQ  QGNQEATAPP  DTMAQPYASA  QFAPPQNGIP  AEYTAPHPHP  APDYTGQTTV  60
61    PEHTLNMYPP  AQTHTEQSAA  DTNAQTVSGT  ATQTDDAAQT  DGQQQTQSSE  NTENKSQPKR  120
121   LHVSNIPFRF  RDPDLRQMFG  QFGKILDVEI  IFNERGSKGF  GFVTFENSAD  ADRAREKLHG  180
181   TVVEGRKIEV  NNATARVMTN  KKTVNPYTNG  WKLNPVVGAV  YSPEFYAGRV  LLCQANQEGS  240
241   PVYSAPSSLV  YTSTMPGFPY  PAATAAAAYR  GAHLRGRGRT  VYNTFRAAAP  PPPIPAYGGV  300
301   VYQDGFYGAD  IYGGYAAYRY  AQPATATAAA  YSDSYGRVYA  ADPYHHTLAP  AATYGVGAVN  360
361   AFAPLTDAKT  RSHADDVGLV  LSSLQASIYR  GGYSRFAPY  399
Nucleotide CDS Sequence (FASTA)
1     ATGGAGGATA  AAGGGAGCAG  GATGGTACAG  CAGGGTAATC  AGGAAGCTAC  AGCACCTCCT  60
61    GACACTATGG  CGCAGCCTTA  TGCCTCAGCC  CAGTTCGCTC  CACCTCAGAA  TGGGATCCCG  120
121   GCAGAATACA  CAGCCCCACA  CCCTCATCCA  GCTCCAGACT  ACACAGGCCA  GACCACAGTT  180
181   CCAGAGCACA  CGTTAAACAT  GTACCCTCCT  GCTCAGACAC  ACACCGAACA  GAGTGCAGCT  240
241   GACACAAATG  CACAAACTGT  CTCCGGCACA  GCCACACAGA  CAGATGATGC  AGCACAGACT  300
301   GACGGCCAGC  AACAGACACA  ATCCTCTGAA  AATACAGAAA  ACAAATCACA  GCCGAAACGG  360
361   CTGCATGTCT  CAAATATACC  CTTCAGATTT  CGAGATCCGG  ATCTGAGACA  AATGTTTGGA  420
421   CAATTTGGTA  AAATCTTAGA  TGTTGAAATT  ATTTTTAATG  AGCGAGGCTC  AAAGGGATTT  480
481   GGTTTCGTAA  CTTTCGAAAA  TAGTGCTGAT  GCGGACAGGG  CGAGGGAGAA  ATTACACGGC  540
541   ACCGTGGTAG  AGGGCCGTAA  AATCGAGGTA  AATAACGCGA  CAGCACGTGT  AATGACAAAT  600
601   AAAAAGACTG  TCAACCCTTA  TACAAATGGC  TGGAAATTAA  ATCCAGTTGT  CGGTGCAGTT  660
661   TATAGTCCAG  AATTCTATGC  AGGCAGGGTG  CTGCTGTGCC  AGGCAAACCA  GGAGGGATCT  720
721   CCCGTGTACA  GTGCCCCCAG  TTCACTAGTA  TACACATCCA  CAATGCCAGG  CTTCCCTTAC  780
781   CCTGCTGCAA  CTGCAGCTGC  TGCTTACAGA  GGTGCACATC  TAAGAGGTCG  AGGTCGCACA  840
841   GTGTACAACA  CGTTTCGTGC  AGCAGCCCCC  CCTCCTCCAA  TTCCAGCCTA  TGGCGGTGTT  900
901   GTTTACCAGG  ATGGATTTTA  TGGTGCAGAC  ATTTATGGTG  GTTATGCTGC  CTACCGGTAT  960
961   GCCCAGCCTG  CCACTGCCAC  TGCCGCTGCC  TACAGTGACA  GTTACGGACG  AGTTTATGCT  1020
1021  GCAGACCCCT  ACCACCACAC  ACTTGCTCCA  GCAGCCACCT  ACGGCGTTGG  TGCCGTGAAT  1080
1081  GCTTTTGCAC  CCTTGACTGA  TGCCAAGACT  AGGAGCCATG  CTGATGATGT  CGGTCTCGTT  1140
1141  CTTTCTTCAT  TACAGGCTAG  TATATACCGA  GGGGGATACA  GCCGTTTTGC  TCCATACTAA  1200

▼ KEYWORD

ID
Family
Complete proteome
mRNA processing
mRNA splicing
Nucleus
Reference proteome
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Molecular Function
RNA binding
Biological Process
MRNA processing
Biological Process
Neuromuscular process controlling balance
Biological Process
Regulation of alternative mRNA splicing, via spliceosome
Biological Process
Regulation of skeletal muscle cell differentiation
Biological Process
RNA splicing

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tag-3364Taeniopygia guttata99.490.0 612
LLPS-Fia-2567Ficedula albicollis99.328e-171 488
LLPS-Anp-0972Anas platyrhynchos98.980.0 615
LLPS-Mod-0355Monodelphis domestica97.161e-156 453
LLPS-Myl-3001Myotis lucifugus96.92e-156 450
LLPS-Ora-1277Ornithorhynchus anatinus96.718e-172 493
LLPS-Mup-1397Mustela putorius furo95.588e-162 468
LLPS-Mam-2759Macaca mulatta95.241e-161 470
LLPS-Poa-3525Pongo abelii95.244e-161 466
LLPS-Rhb-0494Rhinopithecus bieti95.229e-161 466
LLPS-Chs-4273Chlorocebus sabaeus95.072e-169 486
LLPS-Urm-2927Ursus maritimus95.065e-149 434
LLPS-Cas-2920Carlito syrichta94.886e-160 464
LLPS-Gaga-0477Gallus gallus94.360.0 602
LLPS-Man-3685Macaca nemestrina94.38e-161 472
LLPS-Maf-3015Macaca fascicularis94.38e-161 472
LLPS-Sus-3601Sus scrofa94.224e-159 462
LLPS-Orc-1820Oryctolagus cuniculus94.012e-131 384
LLPS-Fec-0511Felis catus93.965e-161 473
LLPS-Hos-0644Homo sapiens93.966e-160 470
LLPS-Pap-2117Pan paniscus93.964e-160 470
LLPS-Pat-1058Pan troglodytes93.966e-160 470
LLPS-Cea-3459Cercocebus atys93.965e-160 470
LLPS-Gog-3482Gorilla gorilla93.964e-160 469
LLPS-Paa-0841Papio anubis93.965e-160 470
LLPS-Mal-1269Mandrillus leucophaeus93.965e-161 468
LLPS-Loa-2123Loxodonta africana93.812e-154 446
LLPS-Otg-4680Otolemur garnettii93.640.0 582
LLPS-Nol-3855Nomascus leucogenys93.621e-159 469
LLPS-Aon-1049Aotus nancymaae93.622e-159 469
LLPS-Ran-3727Rattus norvegicus93.350.0 574
LLPS-Sah-4060Sarcophilus harrisii93.30.0 563
LLPS-Caj-0033Callithrix jacchus93.291e-158 466
LLPS-Aim-0985Ailuropoda melanoleuca92.792e-133 390
LLPS-Caf-4600Canis familiaris92.560.0 579
LLPS-Eqc-4000Equus caballus92.090.0 584
LLPS-Fud-1323Fukomys damarensis92.050.0 578
LLPS-Meg-0224Meleagris gallopavo91.963e-156 450
LLPS-Tut-0015Tursiops truncatus91.790.0 574
LLPS-Bot-1548Bos taurus91.750.0 598
LLPS-Cap-4455Cavia porcellus91.540.0 575
LLPS-Ict-4554Ictidomys tridecemlineatus91.540.0 574
LLPS-Scf-1703Scleropages formosus91.186e-32 128
LLPS-Mum-4742Mus musculus90.820.0 568
LLPS-Leo-2342Lepisosteus oculatus90.050.0 536
LLPS-Anc-1625Anolis carolinensis89.140.0 533
LLPS-Dio-2026Dipodomys ordii83.591e-177 509
LLPS-Dar-0980Danio rerio83.03e-171 491
LLPS-Icp-3902Ictalurus punctatus79.545e-145 424
LLPS-Ova-2375Ovis aries79.427e-119 352
LLPS-Tar-1018Takifugu rubripes76.722e-148 433
LLPS-Scm-2815Scophthalmus maximus76.476e-148 433
LLPS-Orn-2894Oreochromis niloticus69.422e-126 377
LLPS-Gaa-1024Gasterosteus aculeatus68.591e-61 209
LLPS-Cae-2013Caenorhabditis elegans65.482e-30 125
LLPS-Asm-3896Astyanax mexicanus65.385e-100 309
LLPS-Ten-0840Tetraodon nigroviridis62.061e-137 406
LLPS-Mea-0106Mesocricetus auratus58.451e-107 328
LLPS-Pof-1427Poecilia formosa56.593e-72 239
LLPS-Xet-2681Xenopus tropicalis56.21e-128 383
LLPS-Orl-2845Oryzias latipes54.092e-71 238
LLPS-Xim-0110Xiphophorus maculatus53.588e-73 241
LLPS-Lac-0757Latimeria chalumnae53.522e-90 284
LLPS-Ere-0206Erinaceus europaeus45.03e-0960.8
LLPS-Tru-1540Triticum urartu41.674e-0959.3
LLPS-Tra-3046Triticum aestivum41.672e-0960.8
LLPS-Lep-1092Leersia perrieri40.515e-0962.4
LLPS-Dac-1385Daucus carota40.246e-1063.2
LLPS-Sob-1001Sorghum bicolor39.243e-0961.6
LLPS-Prp-2015Prunus persica39.241e-0963.2
LLPS-Brd-0209Brachypodium distachyon39.245e-0961.2
LLPS-Drm-0962Drosophila melanogaster38.896e-1065.1
LLPS-Sot-0829Solanum tuberosum38.19e-0960.1
LLPS-Amt-1984Amborella trichopoda32.327e-1063.5