• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pap-3013
PICALM

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: PICALM
Ensembl Gene: ENSPPAG00000036162.1
Ensembl Protein: ENSPPAP00000026359.1
Organism: Pan paniscus
Taxa ID: 9597
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSGQSLTDRI  TAAQHSVTGS  AVSKTVCKAT  THEIMGPKKK  HLDYLIQCTN  EMNVNIPQLA  60
61    DSLFERTTNS  SWVVVFKSLI  TTHHLMVYGN  ERFIQYLASR  NTLFNLSNFL  DKSGLQGYDM  120
121   STFIRRYSRY  LNEKAVSYRQ  VAFDFTKVKR  GADGVMRTMN  TEKLLKTVPI  IQNQMDALLD  180
181   FNVNSNELTN  GVINAAFMLL  FKDAIRLFAA  YNEGIINLLE  KYFDMKKNQC  KEGLDIYKKF  240
241   LTRMTRISEF  LKVAEQVGID  RGDIPDLSQA  PSSLLDALEQ  HLASLEGKKI  KDSTAASRAT  300
301   TLSNAVSSLA  STGLSLTKVD  EREKQAALEE  EQARLKALKE  QRLKELAKKP  HTSLTTAASP  360
361   VSTSAGGIMT  APAIDIFSTP  SSSNSTSKLP  NDLLDLQQPT  FHPSVHPMST  ASQVASTWGD  420
421   PFSATVDAVD  DAIPSLNPFL  TKSSGDVHLS  ISSDVSTFTT  RTPTHEMFVG  FTPSPVAQPH  480
481   PSAGLNVDFE  SVFGNKSTNV  IVDSGGFDEL  GGLLKPTVAS  QNQNLPVAKL  PPNKLVSDDL  540
541   DSSLANLVGN  LGIGNGTTKN  DVNWSQPGEK  KLTGGSNWQP  KVAPTTAWNA  ATMNGMHFPQ  600
601   YAPPVMAYPA  TTPTGMIGYG  IPPQMGSVPV  MTQPTLIYSQ  PVMRPPNPFG  PVSGAQFLKI  660
661   RHKYTLFFIP  LLH  673
Nucleotide CDS Sequence (FASTA)
1     ATGAATGTGA  ACATCCCACA  GTTGGCAGAC  AGTTTATTTG  AAAGAACTAC  TAATAGTAGT  60
61    TGGGTGGTGG  TCTTCAAATC  TCTCATTACA  ACTCATCATT  TGATGGTGTA  TGGAAATGAG  120
121   CGTTTTATTC  AGTATTTGGC  TTCAAGAAAC  ACGTTGTTTA  ACTTAAGCAA  TTTTTTGGAT  180
181   AAAAGTGGAT  TGCAAGGATA  TGACATGTCT  ACATTTATTA  GGCGGTATAG  TAGATATTTA  240
241   AATGAGAAAG  CAGTTTCATA  CAGACAAGTT  GCATTTGATT  TCACAAAAGT  GAAGAGAGGG  300
301   GCTGATGGAG  TTATGAGAAC  AATGAACACA  GAAAAACTCC  TAAAAACTGT  ACCAATTATT  360
361   CAGAATCAAA  TGGATGCACT  TCTTGATTTT  AATGTTAATA  GCAATGAACT  TACAAATGGG  420
421   GTAATAAATG  CTGCCTTCAT  GCTCCTGTTC  AAAGATGCCA  TTAGACTGTT  TGCAGCATAC  480
481   AATGAAGGAA  TTATTAATTT  GTTGGAAAAA  TATTTTGATA  TGAAAAAGAA  CCAATGCAAA  540
541   GAAGGTCTTG  ACATCTATAA  GAAGTTCCTA  ACTAGGATGA  CAAGAATCTC  AGAGTTCCTC  600
601   AAAGTTGCAG  AGCAAGTTGG  AATTGACAGA  GGTGATATAC  CAGACCTTTC  ACAGGCCCCT  660
661   AGCAGTCTTC  TTGATGCTTT  GGAACAACAT  TTAGCTTCCT  TGGAAGGAAA  GAAAATCAAA  720
721   GATTCTACAG  CTGCAAGCAG  GGCAACTACA  CTTTCCAATG  CAGTCTCTTC  CCTGGCAAGC  780
781   ACTGGTCTAT  CTCTGACCAA  AGTGGATGAA  AGGGAAAAGC  AGGCAGCATT  AGAGGAAGAA  840
841   CAGGCACGTT  TGAAAGCTTT  AAAGGAACAG  CGCCTAAAAG  AACTTGCAAA  GAAACCTCAT  900
901   ACCTCTTTAA  CAACTGCAGC  CTCTCCTGTA  TCCACCTCAG  CAGGAGGGAT  AATGACTGCA  960
961   CCAGCCATTG  ACATATTTTC  TACCCCTAGT  TCTTCTAACA  GCACATCAAA  GCTGCCCAAT  1020
1021  GATCTGCTTG  ATTTGCAGCA  GCCAACTTTT  CACCCATCTG  TACATCCTAT  GTCAACTGCT  1080
1081  TCTCAGGTAG  CAAGTACGTG  GGGAGGATTC  ACTCCTTCTC  CAGTTGCACA  GCCACACCCT  1140
1141  TCAGCTGGCC  TTAATGTTGA  CTTTGAATCT  GTGTTTGGAA  ATAAATCTAC  AAATGTTATT  1200
1201  GTAGATTCTG  GGGGCTTTGA  TGAACTAGGT  GGACTTCTCA  AACCAACAGT  GGCCTCTCAG  1260
1261  AACCAGAACC  TTCCTGTTGC  CAAACTCCCA  CCTAACAAGT  TAGTATCTGA  TGACTTGGAT  1320
1321  TCATCTTTAG  CCAACCTTGT  GGGCAATCTT  GGCATTGGAA  ATGGAACCAC  TAAGAATGAT  1380
1381  GTAAATTGGA  GTCAACCAGG  TGAAAAGAAG  TTAACTGGAG  GATCTAACTG  GCAACCAAAG  1440
1441  GTTGCACCAA  CAACCGCTTG  GAATGCTGCA  ACAATGGCAC  CCCCTGTAAT  GGCCTATCCT  1500
1501  GCTACTACAC  CAACAGGCAT  GATAGGATAT  GGAATTCCTC  CACAAATGGG  AAGTGTCCCT  1560
1561  GTAATGACGC  AACCAACCTT  AATATACAGC  CAGCCTGTCA  TGAGACCTCC  AAACCCCTTT  1620
1621  GGCCCTGTAT  CAGGAGCACA  GATACAGTTT  ATGTAA  1656

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pat-2942Pan troglodytes100.00.01366
LLPS-Mam-0942Macaca mulatta99.70.01361
LLPS-Paa-3335Papio anubis99.70.01361
LLPS-Maf-0457Macaca fascicularis99.70.01333
LLPS-Cea-3366Cercocebus atys99.70.01333
LLPS-Gog-1693Gorilla gorilla99.70.01361
LLPS-Mal-2009Mandrillus leucophaeus99.550.01358
LLPS-Man-4563Macaca nemestrina99.540.01329
LLPS-Poa-4124Pongo abelii99.390.01328
LLPS-Nol-3394Nomascus leucogenys99.390.01313
LLPS-Loa-4327Loxodonta africana99.240.01317
LLPS-Mup-2462Mustela putorius furo99.090.01319
LLPS-Orc-2355Oryctolagus cuniculus98.930.01319
LLPS-Ict-3626Ictidomys tridecemlineatus98.780.01318
LLPS-Fud-2005Fukomys damarensis98.780.01321
LLPS-Cap-3173Cavia porcellus98.630.01320
LLPS-Hos-1582Homo sapiens98.480.01302
LLPS-Ova-4083Ovis aries98.390.01244
LLPS-Caj-2264Callithrix jacchus98.390.01225
LLPS-Bot-1405Bos taurus98.330.01310
LLPS-Aon-2027Aotus nancymaae98.330.01301
LLPS-Eqc-0082Equus caballus98.170.01302
LLPS-Mum-3294Mus musculus97.720.01302
LLPS-Ran-1813Rattus norvegicus97.110.01286
LLPS-Caf-4089Canis familiaris96.820.01269
LLPS-Otg-0637Otolemur garnettii96.660.01269
LLPS-Myl-3376Myotis lucifugus96.20.01279
LLPS-Mea-4230Mesocricetus auratus95.380.01022
LLPS-Sus-4054Sus scrofa95.320.01305
LLPS-Fec-3109Felis catus95.030.01301
LLPS-Fia-0603Ficedula albicollis94.50.01259
LLPS-Tag-3417Taeniopygia guttata93.90.01257
LLPS-Dio-3960Dipodomys ordii93.250.01234
LLPS-Mod-3193Monodelphis domestica92.110.01245
LLPS-Rhb-3436Rhinopithecus bieti92.080.01222
LLPS-Sah-3538Sarcophilus harrisii91.920.01075
LLPS-Ora-2458Ornithorhynchus anatinus91.120.01170
LLPS-Gaga-3918Gallus gallus87.980.01155
LLPS-Pes-3319Pelodiscus sinensis86.620.01050
LLPS-Anc-2492Anolis carolinensis85.130.01190
LLPS-Leo-2864Lepisosteus oculatus80.150.01058
LLPS-Dar-0130Danio rerio75.850.01036
LLPS-Asm-2670Astyanax mexicanus75.420.01050
LLPS-Icp-0240Ictalurus punctatus74.080.0 976
LLPS-Gaa-2435Gasterosteus aculeatus73.014e-152 470
LLPS-Pof-2381Poecilia formosa71.670.0 972
LLPS-Orl-1955Oryzias latipes71.250.0 968
LLPS-Scm-1263Scophthalmus maximus70.650.0 953
LLPS-Orn-3889Oreochromis niloticus70.610.0 882
LLPS-Tar-1162Takifugu rubripes68.180.0 836
LLPS-Aim-3012Ailuropoda melanoleuca66.673e-117 358
LLPS-Anp-3041Anas platyrhynchos63.591e-173 526
LLPS-Ten-2722Tetraodon nigroviridis61.720.0 744
LLPS-Scf-2951Scleropages formosus60.910.0 769
LLPS-Meg-2548Meleagris gallopavo60.890.0 686
LLPS-Xet-3287Xenopus tropicalis60.660.0 733
LLPS-Xim-1211Xiphophorus maculatus60.060.0 745
LLPS-Lac-0847Latimeria chalumnae57.480.0 551
LLPS-Tum-0269Tuber melanosporum34.884e-36 148
LLPS-Asc-1499Aspergillus clavatus33.336e-30 129
LLPS-Scc-1035Schizosaccharomyces cryophilus32.212e-30 130
LLPS-Abg-1372Absidia glauca32.126e-32 133
LLPS-Scj-0527Schizosaccharomyces japonicus32.093e-32 135
LLPS-Nef-1082Neosartorya fischeri32.061e-30 131
LLPS-Aso-0728Aspergillus oryzae32.062e-29 128
LLPS-Asf-0129Aspergillus flavus32.062e-29 128
LLPS-Ast-1257Aspergillus terreus31.952e-29 127
LLPS-Lem-1299Leptosphaeria maculans31.872e-34 144
LLPS-Asfu-0374Aspergillus fumigatus31.684e-30 129
LLPS-Gag-1174Gaeumannomyces graminis31.583e-27 121
LLPS-Mao-0400Magnaporthe oryzae31.392e-30 130
LLPS-Fuo-1434Fusarium oxysporum31.27e-30 129
LLPS-Trv-1613Trichoderma virens31.29e-29 125
LLPS-Cog-1060Colletotrichum gloeosporioides31.27e-29 126
LLPS-Fus-1335Fusarium solani31.21e-29 128
LLPS-Fuv-1487Fusarium verticillioides31.25e-30 129
LLPS-Map-0833Magnaporthe poae31.23e-26 117
LLPS-Cogr-1441Colletotrichum graminicola30.832e-28 125
LLPS-Miv-0166Microbotryum violaceum30.711e-26 120
LLPS-Asn-1220Aspergillus nidulans30.681e-27 122
LLPS-Nec-0230Neurospora crassa30.671e-30 132
LLPS-Beb-0785Beauveria bassiana30.456e-28 123
LLPS-Crn-1163Cryptococcus neoformans30.362e-31 135
LLPS-Coo-0149Colletotrichum orbiculare30.341e-27 122
LLPS-Blg-0117Blumeria graminis30.242e-30 130
LLPS-Asni-0749Aspergillus niger30.239e-30 129
LLPS-Asg-1372Ashbya gossypii30.123e-33 137
LLPS-Phn-1282Phaeosphaeria nodorum29.72e-29 128
LLPS-Trr-0458Trichoderma reesei29.394e-29 126
LLPS-Mel-0806Melampsora laricipopulina29.345e-23 107
LLPS-Scp-1346Schizosaccharomyces pombe29.293e-30 130
LLPS-Pytr-1131Pyrenophora triticirepentis29.211e-30 131
LLPS-Pyt-0692Pyrenophora teres29.213e-30 130
LLPS-Put-1316Puccinia triticina29.143e-25 115
LLPS-Nia-1260Nicotiana attenuata29.094e-29 126
LLPS-Sem-0050Selaginella moellendorffii29.061e-34 142
LLPS-Ved-1364Verticillium dahliae29.06e-29 126
LLPS-Coc-1717Corchorus capsularis28.841e-27 122
LLPS-Pug-1159Puccinia graminis28.811e-24 113
LLPS-Brd-0976Brachypodium distachyon28.788e-30 128
LLPS-Dos-1422Dothistroma septosporum28.683e-26 118
LLPS-Arl-2181Arabidopsis lyrata28.672e-28 124
LLPS-Kop-1418Komagataella pastoris28.622e-28 125
LLPS-Php-1000Physcomitrella patens28.372e-35 145
LLPS-Sot-0084Solanum tuberosum28.262e-30 130
LLPS-Gor-1782Gossypium raimondii27.943e-30 130
LLPS-Pot-2378Populus trichocarpa27.948e-31 131
LLPS-Mae-2369Manihot esculenta27.947e-32 134
LLPS-Mua-0442Musa acuminata27.941e-31 134
LLPS-Orr-1546Oryza rufipogon27.94e-27 120
LLPS-Bro-2339Brassica oleracea27.98e-30 130
LLPS-Orb-1510Oryza barthii27.94e-27 120
LLPS-Brn-3267Brassica napus27.96e-30 130
LLPS-Orni-1658Oryza nivara27.94e-27 120
LLPS-Brr-2414Brassica rapa27.89e-30 129
LLPS-Prp-1317Prunus persica27.571e-30 131
LLPS-Art-2406Arabidopsis thaliana27.574e-29 127
LLPS-Cus-0339Cucumis sativus27.572e-30 130
LLPS-Glm-0500Glycine max27.572e-30 130
LLPS-Thc-0368Theobroma cacao27.572e-30 130
LLPS-Viv-2316Vitis vinifera27.473e-30 129
LLPS-Phv-0396Phaseolus vulgaris27.479e-29 125
LLPS-Sac-1118Saccharomyces cerevisiae27.417e-24 110
LLPS-Usm-1312Ustilago maydis27.255e-26 118
LLPS-Via-1561Vigna angularis27.212e-30 130
LLPS-Sol-2447Solanum lycopersicum27.219e-28 121
LLPS-Hea-0987Helianthus annuus27.122e-26 119
LLPS-Ori-1672Oryza indica27.114e-26 117
LLPS-Spr-0666Sporisorium reilianum27.031e-25 117
LLPS-Dac-2353Daucus carota26.846e-29 125
LLPS-Tru-1369Triticum urartu26.797e-24 110
LLPS-Amt-0415Amborella trichopoda26.742e-28 124
LLPS-Sob-1864Sorghum bicolor26.241e-28 125
LLPS-Sei-1750Setaria italica26.19e-29 126
LLPS-Vir-0680Vigna radiata25.742e-25 115
LLPS-Tra-2854Triticum aestivum25.363e-27 120
LLPS-Osl-1473Ostreococcus lucimarinus25.32e-20 100
LLPS-Met-1076Medicago truncatula25.091e-26 118
LLPS-Orm-1671Oryza meridionalis25.05e-27 120
LLPS-Orp-0348Oryza punctata25.03e-27 120
LLPS-Hov-1139Hordeum vulgare25.03e-27 121
LLPS-Org-0097Oryza glaberrima24.915e-26 117
LLPS-Ors-0177Oryza sativa24.915e-26 117
LLPS-Orbr-2287Oryza brachyantha24.916e-27 120
LLPS-Zem-2098Zea mays24.633e-27 120
LLPS-Lep-0628Leersia perrieri24.549e-27 119
LLPS-Gas-1310Galdieria sulphuraria24.181e-27 122