• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ict-3626
PICALM

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: PICALM
Ensembl Gene: ENSSTOG00000008689.3
Ensembl Protein: ENSSTOP00000007792.3
Organism: Ictidomys tridecemlineatus
Taxa ID: 43179
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSGQSLTDRI  TAAQHSVTGS  AVSKTVCKAT  THEIMGPKKK  HLDYLIQCTN  EMNVNIPQLA  60
61    DSLFERTTNS  SWVVVFKSLI  TTHHLMVYGN  ERFIQYLASR  NTLFNLSNFL  DKSGLQGYDM  120
121   STFIRRYSRY  LNEKAVSYRQ  VAFDFTKVKR  GADGVMRTMN  TEKLLKTVPI  IQNQMDALLD  180
181   FNVNSNELTN  GVINAAFMLL  FKDAIRLFAA  YNEGIINLLE  KYFDMKKNQC  KEGLDIYKKF  240
241   LTRMTRISEF  LKVAEQVGID  RGDIPDLSQA  PSSLLDALEQ  HLASLEGKKI  KDSTAASRAT  300
301   TLSNAVSSLA  STGLSLTKVD  EREKQAALEE  EQARLKALKE  QRLKELAKKP  HTSLTTAASP  360
361   VSTSAGGIMT  APAIDIFSTP  SSSNSTSKLP  NDLLDLQQPT  FHPSVHPMSS  TSQVASTWGD  420
421   PFSATLDAVD  DAIPSLNPFL  TKSSGDVHLP  ISSDVSTFTT  RTPTHEMFVG  FTPSPVAQSH  480
481   PSAGLNVDFE  SVFGNKSTNV  IVDSGGFDEL  GGLLKPTVAS  QNQSLPVAKL  PPNKLVSDDL  540
541   DSSLANLVGN  LGIGNGTTKN  DVNWSQPGEK  KLTGGSNWQP  KVAPTTAWNA  ATMNGMHFPQ  600
601   YAPPVMAYPA  TTPTGMLGYG  IPPQMGSVPV  MTQPTLIYSQ  PVMRPPNPFG  PVSGAQIQFM  660
Nucleotide CDS Sequence (FASTA)
1     ATGTCTGGCC  AGAGCCTGAC  GGACCGAATC  ACCGCCGCCC  AGCACAGTGT  CACCGGCTCC  60
61    GCGGTGTCCA  AGACAGTATG  CAAGGCCACG  ACCCACGAGA  TCATGGGCCC  CAAGAAAAAG  120
121   CACCTGGACT  ACTTAATTCA  GTGCACAAAT  GAGATGAATG  TGAACATCCC  ACAGTTGGCA  180
181   GACAGTTTAT  TTGAAAGAAC  TACTAACAGT  AGTTGGGTGG  TGGTCTTCAA  ATCTCTCATT  240
241   ACAACTCACC  ATCTGATGGT  GTATGGAAAT  GAGCGTTTTA  TTCAGTATTT  GGCATCCAGG  300
301   AACACATTGT  TTAACTTAAG  CAATTTTTTG  GATAAAAGTG  GATTACAAGG  ATATGACATG  360
361   TCTACATTCA  TTAGGCGGTA  TAGTAGATAT  TTAAATGAAA  AAGCAGTTTC  ATACAGACAA  420
421   GTTGCATTTG  ATTTCACAAA  AGTGAAGAGA  GGGGCTGATG  GAGTTATGAG  AACAATGAAC  480
481   ACAGAAAAAC  TCTTAAAAAC  TGTACCAATT  ATTCAAAATC  AAATGGATGC  ACTCCTTGAT  540
541   TTTAATGTTA  ATAGCAATGA  ACTTACAAAT  GGGGTAATAA  ATGCTGCCTT  CATGCTCCTG  600
601   TTCAAAGATG  CCATTAGACT  ATTTGCAGCA  TACAATGAAG  GAATTATTAA  TCTGTTGGAA  660
661   AAATATTTTG  ATATGAAAAA  GAACCAGTGC  AAAGAAGGTC  TTGACATCTA  TAAGAAGTTC  720
721   TTAACTAGGA  TGACAAGAAT  CTCAGAGTTT  CTCAAAGTTG  CAGAGCAAGT  TGGAATTGAC  780
781   AGAGGTGATA  TACCAGACCT  TTCACAGGCC  CCCAGTAGTC  TTCTTGATGC  TTTGGAACAA  840
841   CATTTAGCTT  CCTTGGAAGG  AAAGAAAATC  AAAGATTCTA  CAGCTGCAAG  CAGGGCCACA  900
901   ACACTTTCCA  ATGCAGTCTC  TTCTCTGGCA  AGCACTGGCC  TATCTCTGAC  CAAAGTGGAT  960
961   GAAAGGGAAA  AGCAAGCAGC  ATTAGAGGAA  GAACAGGCAC  GTTTAAAAGC  TTTAAAGGAG  1020
1021  CAGCGCCTAA  AAGAACTTGC  AAAGAAACCT  CATACCTCTT  TAACAACTGC  AGCCTCTCCT  1080
1081  GTGTCCACCT  CAGCAGGGGG  AATAATGACT  GCACCAGCCA  TTGACATATT  TTCTACTCCT  1140
1141  AGTTCTTCTA  ACAGCACATC  AAAGCTGCCA  AATGACCTGC  TTGATTTGCA  GCAGCCAACT  1200
1201  TTTCATCCAT  CTGTACATCC  TATGTCAAGT  ACTTCTCAGG  TAGCAAGTAC  ATGGGGAGAT  1260
1261  CCTTTCTCTG  CTACTTTAGA  TGCTGTTGAT  GATGCCATTC  CAAGCTTAAA  TCCTTTCCTC  1320
1321  ACAAAAAGTA  GTGGTGATGT  TCACCTTCCC  ATTTCTTCAG  ATGTATCCAC  TTTTACTACT  1380
1381  AGGACACCTA  CTCATGAAAT  GTTTGTTGGA  TTCACTCCTT  CTCCAGTTGC  ACAGTCACAT  1440
1441  CCTTCAGCTG  GCCTTAATGT  TGACTTTGAA  TCTGTGTTTG  GAAATAAATC  CACAAATGTT  1500
1501  ATTGTAGATT  CCGGGGGCTT  TGATGAACTA  GGTGGACTTC  TCAAACCAAC  AGTGGCCTCT  1560
1561  CAGAACCAGA  GTCTTCCTGT  TGCCAAGCTC  CCACCTAACA  AGTTGGTGTC  TGATGACTTG  1620
1621  GATTCATCTT  TAGCCAACCT  TGTGGGTAAT  CTTGGCATTG  GAAATGGAAC  CACTAAGAAT  1680
1681  GATGTAAATT  GGAGTCAGCC  AGGTGAAAAG  AAATTGACTG  GAGGATCTAA  CTGGCAACCA  1740
1741  AAGGTTGCAC  CAACAACTGC  TTGGAATGCT  GCAACAATGG  CACCTCCTGT  AATGGCCTAT  1800
1801  CCTGCTACTA  CACCAACAGG  CATGCTAGGA  TATGGCATTC  CACCTCAAAT  GGGAAGTGTA  1860
1861  CCTGTAATGA  CACAACCAAC  CTTAATATAC  AGCCAGCCTG  TCATGAGACC  ACCAAACCCC  1920
1921  TTCGGCCCTG  TATCAGGAGC  ACAGATACAG  TTTATGTAA  1959

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-2005Fukomys damarensis98.940.01330
LLPS-Mal-2009Mandrillus leucophaeus98.930.01320
LLPS-Paa-3335Papio anubis98.930.01320
LLPS-Cea-3366Cercocebus atys98.930.01321
LLPS-Maf-0457Macaca fascicularis98.930.01321
LLPS-Mam-0942Macaca mulatta98.930.01320
LLPS-Mup-2462Mustela putorius furo98.790.01326
LLPS-Cap-3173Cavia porcellus98.790.01328
LLPS-Man-4563Macaca nemestrina98.780.01318
LLPS-Pat-2942Pan troglodytes98.780.01318
LLPS-Pap-3013Pan paniscus98.780.01318
LLPS-Gog-1693Gorilla gorilla98.630.01315
LLPS-Poa-4124Pongo abelii98.630.01316
LLPS-Loa-4327Loxodonta africana98.630.01316
LLPS-Nol-3394Nomascus leucogenys98.620.01302
LLPS-Orc-2355Oryctolagus cuniculus98.480.01318
LLPS-Ova-4083Ovis aries98.080.01248
LLPS-Mum-3294Mus musculus97.880.01313
LLPS-Bot-1405Bos taurus97.870.01308
LLPS-Eqc-0082Equus caballus97.870.01300
LLPS-Caj-2264Callithrix jacchus97.580.01217
LLPS-Hos-1582Homo sapiens97.580.01299
LLPS-Ran-1813Rattus norvegicus97.270.01297
LLPS-Aon-2027Aotus nancymaae97.270.01293
LLPS-Otg-0637Otolemur garnettii96.530.01277
LLPS-Caf-4089Canis familiaris96.510.01267
LLPS-Myl-3376Myotis lucifugus96.040.01280
LLPS-Mea-4230Mesocricetus auratus95.40.01030
LLPS-Sus-4054Sus scrofa95.340.01313
LLPS-Fec-3109Felis catus95.180.01305
LLPS-Fia-0603Ficedula albicollis94.040.01254
LLPS-Tag-3417Taeniopygia guttata93.180.01259
LLPS-Dio-3960Dipodomys ordii92.660.01234
LLPS-Mod-3193Monodelphis domestica91.810.01244
LLPS-Sah-3538Sarcophilus harrisii91.620.01080
LLPS-Ora-2458Ornithorhynchus anatinus91.470.01181
LLPS-Rhb-3436Rhinopithecus bieti91.150.01180
LLPS-Gaga-3918Gallus gallus88.030.01161
LLPS-Pes-3319Pelodiscus sinensis86.360.01052
LLPS-Anc-2492Anolis carolinensis85.610.01199
LLPS-Leo-2864Lepisosteus oculatus79.940.01065
LLPS-Dar-0130Danio rerio76.960.01037
LLPS-Asm-2670Astyanax mexicanus75.140.01046
LLPS-Icp-0240Ictalurus punctatus74.230.0 976
LLPS-Gaa-2435Gasterosteus aculeatus73.011e-152 471
LLPS-Pof-2381Poecilia formosa71.530.0 973
LLPS-Orn-3889Oreochromis niloticus70.780.0 889
LLPS-Orl-1955Oryzias latipes70.330.0 958
LLPS-Scm-1263Scophthalmus maximus69.120.0 939
LLPS-Tar-1162Takifugu rubripes67.670.0 841
LLPS-Aim-3012Ailuropoda melanoleuca66.671e-117 359
LLPS-Anp-3041Anas platyrhynchos63.364e-174 526
LLPS-Ten-2722Tetraodon nigroviridis61.80.0 754
LLPS-Scf-2951Scleropages formosus61.090.0 779
LLPS-Meg-2548Meleagris gallopavo61.080.0 695
LLPS-Xet-3287Xenopus tropicalis60.840.0 740
LLPS-Xim-1211Xiphophorus maculatus60.120.0 749
LLPS-Lac-0847Latimeria chalumnae57.920.0 553
LLPS-Tum-0269Tuber melanosporum34.882e-36 149
LLPS-Asc-1499Aspergillus clavatus33.334e-30 129
LLPS-Abg-1372Absidia glauca32.354e-32 133
LLPS-Scc-1035Schizosaccharomyces cryophilus32.212e-30 130
LLPS-Scj-0527Schizosaccharomyces japonicus32.092e-32 136
LLPS-Aso-0728Aspergillus oryzae32.061e-29 128
LLPS-Asf-0129Aspergillus flavus32.061e-29 128
LLPS-Nef-1082Neosartorya fischeri32.068e-31 132
LLPS-Ast-1257Aspergillus terreus31.951e-29 128
LLPS-Lem-1299Leptosphaeria maculans31.879e-35 144
LLPS-Asfu-0374Aspergillus fumigatus31.683e-30 130
LLPS-Gag-1174Gaeumannomyces graminis31.582e-27 122
LLPS-Mao-0400Magnaporthe oryzae31.391e-30 131
LLPS-Fuv-1487Fusarium verticillioides31.23e-30 130
LLPS-Map-0833Magnaporthe poae31.22e-26 117
LLPS-Trv-1613Trichoderma virens31.25e-29 126
LLPS-Fuo-1434Fusarium oxysporum31.24e-30 130
LLPS-Fus-1335Fusarium solani31.27e-30 129
LLPS-Cog-1060Colletotrichum gloeosporioides31.25e-29 127
LLPS-Cogr-1441Colletotrichum graminicola30.838e-29 126
LLPS-Miv-0166Microbotryum violaceum30.716e-27 120
LLPS-Asn-1220Aspergillus nidulans30.681e-27 122
LLPS-Nec-0230Neurospora crassa30.676e-31 132
LLPS-Beb-0785Beauveria bassiana30.455e-28 124
LLPS-Crn-1163Cryptococcus neoformans30.361e-31 135
LLPS-Coo-0149Colletotrichum orbiculare30.348e-28 123
LLPS-Blg-0117Blumeria graminis30.242e-30 130
LLPS-Asni-0749Aspergillus niger30.237e-30 129
LLPS-Asg-1372Ashbya gossypii30.122e-33 137
LLPS-Phn-1282Phaeosphaeria nodorum29.78e-30 129
LLPS-Trr-0458Trichoderma reesei29.393e-29 127
LLPS-Mel-0806Melampsora laricipopulina29.344e-23 107
LLPS-Scp-1346Schizosaccharomyces pombe29.293e-30 130
LLPS-Pyt-0692Pyrenophora teres29.211e-30 131
LLPS-Pytr-1131Pyrenophora triticirepentis29.217e-31 132
LLPS-Put-1316Puccinia triticina29.142e-25 116
LLPS-Nia-1260Nicotiana attenuata29.093e-29 127
LLPS-Sem-0050Selaginella moellendorffii29.068e-35 143
LLPS-Ved-1364Verticillium dahliae29.04e-29 127
LLPS-Coc-1717Corchorus capsularis28.847e-28 122
LLPS-Pug-1159Puccinia graminis28.811e-24 114
LLPS-Brd-0976Brachypodium distachyon28.787e-30 129
LLPS-Dos-1422Dothistroma septosporum28.682e-26 119
LLPS-Arl-2181Arabidopsis lyrata28.672e-28 124
LLPS-Kop-1418Komagataella pastoris28.621e-28 125
LLPS-Php-1000Physcomitrella patens28.372e-35 145
LLPS-Sot-0084Solanum tuberosum28.262e-30 130
LLPS-Mua-0442Musa acuminata27.948e-32 134
LLPS-Pot-2378Populus trichocarpa27.947e-31 131
LLPS-Gor-1782Gossypium raimondii27.942e-30 130
LLPS-Mae-2369Manihot esculenta27.945e-32 135
LLPS-Brn-3267Brassica napus27.95e-30 130
LLPS-Orb-1510Oryza barthii27.92e-27 121
LLPS-Orni-1658Oryza nivara27.93e-27 120
LLPS-Orr-1546Oryza rufipogon27.93e-27 121
LLPS-Bro-2339Brassica oleracea27.96e-30 130
LLPS-Brr-2414Brassica rapa27.86e-30 130
LLPS-Cus-0339Cucumis sativus27.571e-30 131
LLPS-Glm-0500Glycine max27.571e-30 130
LLPS-Thc-0368Theobroma cacao27.572e-30 130
LLPS-Prp-1317Prunus persica27.578e-31 131
LLPS-Viv-2316Vitis vinifera27.573e-30 130
LLPS-Art-2406Arabidopsis thaliana27.573e-29 127
LLPS-Phv-0396Phaseolus vulgaris27.478e-29 125
LLPS-Sac-1118Saccharomyces cerevisiae27.413e-24 111
LLPS-Usm-1312Ustilago maydis27.252e-26 119
LLPS-Via-1561Vigna angularis27.212e-30 130
LLPS-Sol-2447Solanum lycopersicum27.217e-28 122
LLPS-Hea-0987Helianthus annuus27.121e-26 119
LLPS-Ori-1672Oryza indica27.113e-26 117
LLPS-Spr-0666Sporisorium reilianum27.037e-26 117
LLPS-Dac-2353Daucus carota26.844e-29 126
LLPS-Tru-1369Triticum urartu26.795e-24 110
LLPS-Amt-0415Amborella trichopoda26.741e-28 124
LLPS-Sob-1864Sorghum bicolor26.248e-29 125
LLPS-Sei-1750Setaria italica26.18e-29 126
LLPS-Vir-0680Vigna radiata25.742e-25 115
LLPS-Tra-2854Triticum aestivum25.362e-27 121
LLPS-Osl-1473Ostreococcus lucimarinus25.32e-20 100
LLPS-Met-1076Medicago truncatula25.091e-26 119
LLPS-Hov-1139Hordeum vulgare25.03e-27 121
LLPS-Orm-1671Oryza meridionalis25.03e-27 120
LLPS-Orp-0348Oryza punctata25.02e-27 121
LLPS-Org-0097Oryza glaberrima24.914e-26 117
LLPS-Ors-0177Oryza sativa24.914e-26 117
LLPS-Orbr-2287Oryza brachyantha24.914e-27 120
LLPS-Zem-2098Zea mays24.632e-27 121
LLPS-Lep-0628Leersia perrieri24.548e-27 119
LLPS-Gas-1310Galdieria sulphuraria24.186e-28 123