• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Otg-1631
POLR1C

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: RNA polymerase I and III subunit C
Gene Name: POLR1C
Ensembl Gene: ENSOGAG00000016318.2
Ensembl Protein: ENSOGAP00000014607.2
Organism: Otolemur garnettii
Taxa ID: 30611
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Nucleolus, P-body, Stress granule, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSOGAT00000016322.2ENSOGAP00000014607.2
UniProtH0XF38, H0XF38_OTOGA
GeneBankAAQR03061215

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAVQAVEEM  RNRVVLGEFG  VRNVHTTDFP  GNYSGYDDAW  DQDRFEKNFR  VDVVHMDENT  60
61    LEFDMVGIDA  AIANAFRRIL  LAEVPTMAVE  KVLVYNNTSI  VQDEILAHRL  GLIPIHADPR  120
121   LFEYRNQGEG  DEEGTEIDTL  QFRLQVRCTR  NPHAAKDSSD  PNELYVNHKV  YTRHMMWVPL  180
181   GNQADLFPEG  TIRPVHDDIL  IAQLRPGQEI  DLLMHCVKGI  GKDHAKFSPV  ATASYRLLPD  240
241   ITLLKPVEGE  AAEELSQCFS  PGVIEVQEIQ  GKKVARVVNP  RLDTFSREIF  RHEKLKKIVQ  300
301   LARVRDHYIF  SVESTGVLPP  DVLVSEAIKI  LMGKCQRFLD  ELEAVQMD  348
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGCAG  TTCAGGCTGT  GGAGGAGATG  CGGAACCGCG  TGGTTCTAGG  GGAGTTCGGA  60
61    GTTCGCAATG  TTCATACCAC  AGACTTTCCT  GGAAACTATT  CCGGTTATGA  TGATGCCTGG  120
121   GACCAGGACC  GCTTCGAGAA  GAATTTTCGT  GTGGATGTGG  TACACATGGA  TGAAAACACA  180
181   TTGGAGTTTG  ACATGGTGGG  AATTGATGCA  GCCATTGCCA  ATGCTTTCCG  ACGGATCCTA  240
241   TTAGCTGAGG  TACCAACTAT  GGCTGTGGAA  AAGGTCCTGG  TATACAACAA  CACATCCATT  300
301   GTCCAGGATG  AAATCCTGGC  TCATCGCTTG  GGACTTATTC  CCATTCATGC  TGATCCCCGT  360
361   CTGTTTGAGT  ATCGGAACCA  AGGTGAGGGA  GATGAAGAAG  GCACAGAAAT  AGATACTCTG  420
421   CAGTTTCGTT  TGCAAGTCAG  GTGTACTAGG  AACCCCCATG  CTGCTAAAGA  CTCCTCAGAT  480
481   CCCAATGAAC  TCTATGTGAA  CCACAAAGTG  TATACCAGAC  ACATGATGTG  GGTCCCTCTG  540
541   GGGAACCAGG  CTGACCTTTT  CCCAGAGGGC  ACTATCCGAC  CAGTGCATGA  TGATATCCTC  600
601   ATTGCTCAGC  TGCGGCCTGG  CCAGGAGATT  GACCTGCTTA  TGCACTGTGT  CAAGGGGATT  660
661   GGCAAAGATC  ATGCCAAATT  TTCACCAGTG  GCAACAGCCA  GTTACAGGCT  CCTGCCAGAC  720
721   ATCACCCTGC  TTAAGCCTGT  GGAAGGGGAA  GCAGCTGAGG  AGTTAAGCCA  GTGCTTCTCA  780
781   CCTGGTGTTA  TTGAGGTGCA  GGAAATCCAA  GGCAAAAAGG  TGGCTAGAGT  TGTCAATCCC  840
841   CGGCTAGACA  CCTTCAGCAG  GGAAATTTTC  CGGCACGAGA  AGCTAAAAAA  GATTGTACAG  900
901   CTTGCCCGGG  TTCGGGACCA  TTATATCTTC  TCTGTTGAGT  CAACGGGTGT  GTTGCCACCG  960
961   GATGTGCTGG  TAAGCGAAGC  CATCAAAATA  CTCATGGGGA  AGTGCCAACG  ATTCTTGGAT  1020
1021  GAACTTGAAG  CAGTTCAGAT  GGACTGA  1047

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-0094Sus scrofa93.680.0 653
LLPS-Paa-2288Papio anubis93.10.0 665
LLPS-Cea-1040Cercocebus atys93.10.0 665
LLPS-Mal-0572Mandrillus leucophaeus92.820.0 662
LLPS-Chs-2325Chlorocebus sabaeus92.820.0 665
LLPS-Maf-0562Macaca fascicularis92.820.0 664
LLPS-Mam-3012Macaca mulatta92.820.0 664
LLPS-Man-0396Macaca nemestrina92.820.0 664
LLPS-Orc-0384Oryctolagus cuniculus92.820.0 666
LLPS-Myl-0961Myotis lucifugus92.530.0 664
LLPS-Gog-0513Gorilla gorilla92.530.0 664
LLPS-Cap-0472Cavia porcellus92.530.0 664
LLPS-Hos-2159Homo sapiens92.530.0 664
LLPS-Pap-0728Pan paniscus92.530.0 664
LLPS-Pat-0287Pan troglodytes92.530.0 664
LLPS-Bot-0027Bos taurus92.240.0 662
LLPS-Ova-0751Ovis aries92.240.0 661
LLPS-Ere-0166Erinaceus europaeus92.240.0 663
LLPS-Fud-1041Fukomys damarensis92.240.0 660
LLPS-Poa-2772Pongo abelii92.240.0 663
LLPS-Ict-1899Ictidomys tridecemlineatus92.240.0 661
LLPS-Cas-0060Carlito syrichta92.240.0 661
LLPS-Rhb-1174Rhinopithecus bieti92.240.0 663
LLPS-Eqc-1243Equus caballus91.950.0 662
LLPS-Aon-0025Aotus nancymaae91.670.0 662
LLPS-Mea-0280Mesocricetus auratus91.670.0 652
LLPS-Caf-1355Canis familiaris91.670.0 660
LLPS-Dio-0379Dipodomys ordii91.380.0 657
LLPS-Mup-1468Mustela putorius furo91.380.0 656
LLPS-Ran-1242Rattus norvegicus91.380.0 650
LLPS-Caj-1804Callithrix jacchus91.380.0 659
LLPS-Fec-1689Felis catus91.380.0 656
LLPS-Urm-0152Ursus maritimus91.090.0 656
LLPS-Aim-2483Ailuropoda melanoleuca90.80.0 653
LLPS-Mum-0072Mus musculus90.80.0 646
LLPS-Nol-0421Nomascus leucogenys90.230.0 644
LLPS-Loa-0181Loxodonta africana90.10.0 560
LLPS-Mod-1612Monodelphis domestica86.010.0 527
LLPS-Ora-0078Ornithorhynchus anatinus81.610.0 597
LLPS-Anc-0838Anolis carolinensis81.550.0 515
LLPS-Tag-0989Taeniopygia guttata80.240.0 561
LLPS-Pes-0148Pelodiscus sinensis79.890.0 592
LLPS-Fia-0926Ficedula albicollis79.690.0 542
LLPS-Gaga-0717Gallus gallus79.60.0 578
LLPS-Anp-0491Anas platyrhynchos79.142e-171 486
LLPS-Sah-1950Sarcophilus harrisii78.160.0 549
LLPS-Xet-0786Xenopus tropicalis75.930.0 541
LLPS-Leo-0342Lepisosteus oculatus75.626e-176 501
LLPS-Meg-0890Meleagris gallopavo75.091e-159 456
LLPS-Scf-0423Scleropages formosus73.780.0 541
LLPS-Asm-0135Astyanax mexicanus73.20.0 531
LLPS-Icp-1707Ictalurus punctatus72.060.0 532
LLPS-Orn-1493Oreochromis niloticus71.920.0 535
LLPS-Xim-2365Xiphophorus maculatus71.630.0 535
LLPS-Pof-0330Poecilia formosa71.060.0 537
LLPS-Ten-0112Tetraodon nigroviridis70.875e-60 196
LLPS-Scm-0841Scophthalmus maximus70.20.0 534
LLPS-Orl-0725Oryzias latipes70.033e-180 511
LLPS-Dar-1172Danio rerio69.160.0 530
LLPS-Tar-0813Takifugu rubripes68.680.0 514
LLPS-Gaa-0094Gasterosteus aculeatus65.725e-171 488
LLPS-Lac-0286Latimeria chalumnae62.578e-133 389
LLPS-Cii-0396Ciona intestinalis53.891e-132 389
LLPS-Drm-0991Drosophila melanogaster51.751e-114 343
LLPS-Abg-0941Absidia glauca51.664e-123 365
LLPS-Pug-0074Puccinia graminis50.162e-105 320
LLPS-Scp-0341Schizosaccharomyces pombe50.05e-114 342
LLPS-Tum-0270Tuber melanosporum50.03e-104 318
LLPS-Crn-0311Cryptococcus neoformans48.794e-104 317
LLPS-Gor-0314Gossypium raimondii48.21e-83 263
LLPS-Mel-0232Melampsora laricipopulina48.192e-105 321
LLPS-Scj-0024Schizosaccharomyces japonicus47.296e-103 314
LLPS-Spr-0186Sporisorium reilianum47.112e-103 317
LLPS-Put-0184Puccinia triticina47.099e-99 304
LLPS-Usm-0914Ustilago maydis46.825e-103 316
LLPS-Coo-0821Colletotrichum orbiculare46.763e-104 318
LLPS-Cogr-1107Colletotrichum graminicola46.761e-103 317
LLPS-Scc-0753Schizosaccharomyces cryophilus46.653e-107 325
LLPS-Sem-0327Selaginella moellendorffii46.612e-92 287
LLPS-Thc-1546Theobroma cacao46.613e-91 285
LLPS-Cae-0103Caenorhabditis elegans46.187e-98 301
LLPS-Kop-0270Komagataella pastoris46.044e-95 293
LLPS-Sac-0408Saccharomyces cerevisiae46.042e-100 307
LLPS-Gas-0006Galdieria sulphuraria45.795e-68 222
LLPS-Art-2556Arabidopsis thaliana45.634e-89 279
LLPS-Glm-0244Glycine max45.612e-85 270
LLPS-Arl-0327Arabidopsis lyrata45.565e-87 274
LLPS-Phn-0236Phaeosphaeria nodorum45.485e-90 281
LLPS-Aso-0670Aspergillus oryzae45.451e-96 298
LLPS-Asf-0377Aspergillus flavus45.451e-96 298
LLPS-Asg-0057Ashbya gossypii45.439e-96 296
LLPS-Orp-0434Oryza punctata45.373e-77 248
LLPS-Map-0655Magnaporthe poae45.074e-91 284
LLPS-Cog-0270Colletotrichum gloeosporioides45.074e-99 305
LLPS-Coc-0546Corchorus capsularis45.041e-87 275
LLPS-Fus-0797Fusarium solani45.037e-87 273
LLPS-Asn-0130Aspergillus nidulans44.873e-99 305
LLPS-Ast-0099Aspergillus terreus44.854e-96 297
LLPS-Mae-0069Manihot esculenta44.853e-90 282
LLPS-Lep-0216Leersia perrieri44.753e-77 248
LLPS-Nec-1035Neurospora crassa44.662e-96 298
LLPS-Asni-0319Aspergillus niger44.514e-96 296
LLPS-Trr-0337Trichoderma reesei44.443e-85 269
LLPS-Cus-0001Cucumis sativus44.322e-84 268
LLPS-Chc-0260Chondrus crispus44.265e-24 101
LLPS-Pot-0647Populus trichocarpa44.254e-90 282
LLPS-Sot-0477Solanum tuberosum44.141e-93 291
LLPS-Sol-0491Solanum lycopersicum44.145e-93 290
LLPS-Viv-1197Vitis vinifera44.146e-91 284
LLPS-Pytr-0600Pyrenophora triticirepentis44.125e-93 289
LLPS-Miv-0052Microbotryum violaceum44.112e-88 276
LLPS-Php-0183Physcomitrella patens44.17e-92 286
LLPS-Blg-0148Blumeria graminis44.084e-85 269
LLPS-Asfu-0587Aspergillus fumigatus44.041e-100 309
LLPS-Yal-0044Yarrowia lipolytica44.016e-85 267
LLPS-Via-1077Vigna angularis43.911e-81 260
LLPS-Fuv-0112Fusarium verticillioides43.911e-85 271
LLPS-Mua-1653Musa acuminata43.919e-86 270
LLPS-Fuo-0562Fusarium oxysporum43.911e-85 270
LLPS-Ved-0373Verticillium dahliae43.792e-94 293
LLPS-Nef-0319Neosartorya fischeri43.771e-99 306
LLPS-Scs-0086Sclerotinia sclerotiorum43.722e-92 288
LLPS-Nia-1512Nicotiana attenuata43.62e-90 283
LLPS-Pyt-0261Pyrenophora teres43.583e-91 285
LLPS-Trv-0347Trichoderma virens43.552e-83 264
LLPS-Lem-1225Leptosphaeria maculans43.499e-95 294
LLPS-Asc-0155Aspergillus clavatus43.492e-98 303
LLPS-Vir-0430Vigna radiata43.342e-80 257
LLPS-Brn-0268Brassica napus43.134e-84 266
LLPS-Orbr-0191Oryza brachyantha42.667e-79 253
LLPS-Amt-0638Amborella trichopoda42.522e-64 213
LLPS-Brr-0686Brassica rapa42.511e-83 266
LLPS-Beb-0575Beauveria bassiana42.462e-83 265
LLPS-Gag-0275Gaeumannomyces graminis42.372e-88 277
LLPS-Tru-0886Triticum urartu42.31e-70 243
LLPS-Bro-0488Brassica oleracea42.251e-82 263
LLPS-Phv-0517Phaseolus vulgaris41.84e-81 259
LLPS-Prp-1946Prunus persica41.731e-82 263
LLPS-Dos-0046Dothistroma septosporum41.739e-83 263
LLPS-Met-1180Medicago truncatula41.712e-81 260
LLPS-Orgl-1779Oryza glumaepatula41.679e-73 240
LLPS-Orb-0910Oryza barthii41.675e-74 240
LLPS-Orni-0930Oryza nivara41.675e-74 240
LLPS-Orr-0273Oryza rufipogon41.675e-74 240
LLPS-Org-0040Oryza glaberrima41.673e-75 243
LLPS-Ors-0914Oryza sativa41.672e-75 244
LLPS-Zyt-0168Zymoseptoria tritici41.625e-88 279
LLPS-Hea-1070Helianthus annuus41.54e-84 266
LLPS-Mao-0872Magnaporthe oryzae41.278e-89 278
LLPS-Sei-0057Setaria italica41.01e-81 260
LLPS-Hov-0047Hordeum vulgare40.965e-77 249
LLPS-Zem-0476Zea mays40.832e-79 254
LLPS-Tra-1682Triticum aestivum40.689e-78 249
LLPS-Ori-0111Oryza indica40.613e-76 246
LLPS-Sob-0988Sorghum bicolor40.286e-80 255
LLPS-Brd-0536Brachypodium distachyon40.061e-75 244
LLPS-Dac-0023Daucus carota37.864e-56 190
LLPS-Osl-0622Ostreococcus lucimarinus37.52e-71 233
LLPS-Chr-0173Chlamydomonas reinhardtii36.761e-62 211
LLPS-Cym-0628Cyanidioschyzon merolae31.254e-38 145