• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mod-1612
POLR1C

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: RNA polymerase I and III subunit C
Gene Name: POLR1C
Ensembl Gene: ENSMODG00000018964.3
Ensembl Protein: ENSMODP00000023660.3
Organism: Monodelphis domestica
Taxa ID: 13616
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Nucleolus, P-body, Stress granule, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSMODT00000024080.3ENSMODP00000023660.3
UniProtF7G057, F7G057_MONDO

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDENSLEFDM  IGIDAAIANA  FRRILLAEVP  TMAVEKVFVY  NNTSIVQDEI  LAHRLGLIPI  60
61    RADPRLFEYR  NQGDEDGTEI  DTLQFQLKVK  CTRNPQAAKD  SSDPNELYLN  HKVYTKHMTW  120
121   IPLGNQADVF  PEGTIRPVHD  DILIAQLRPG  QELDLLMHCV  KGIGKDHAKF  SPVATASYRL  180
181   LPDITLLQPI  EGEAAEELSQ  CFSPGVIQVQ  DVKGKKVATV  ANPRLDTFSR  EIFRHENLKK  240
241   LVRLARVRDH  YIFSVESTGV  LPPEVLVSEA  IKVLMGKCRR  FMDELDSVQM  D  291
Nucleotide CDS Sequence (FASTA)
1     ATGGATGAAA  ACTCGCTGGA  ATTTGACATG  ATTGGAATTG  ATGCTGCCAT  TGCTAACGCT  60
61    TTTCGGAGGA  TCTTGTTAGC  TGAGGTTCCA  ACCATGGCTG  TGGAAAAAGT  CTTTGTGTAC  120
121   AACAATACAT  CCATAGTGCA  GGATGAGATA  CTGGCCCATC  GTTTGGGTCT  CATTCCCATT  180
181   CGAGCTGATC  CCCGGCTTTT  TGAGTATCGG  AACCAAGGTG  ATGAAGATGG  TACTGAGATA  240
241   GACACTTTGC  AATTTCAGCT  GAAGGTCAAG  TGTACTCGTA  ATCCTCAAGC  TGCCAAAGAC  300
301   TCCTCTGACC  CCAATGAACT  TTATCTTAAT  CATAAAGTAT  ACACCAAACA  CATGACATGG  360
361   ATACCCCTGG  GAAACCAAGC  AGATGTTTTC  CCGGAAGGCA  CCATTCGTCC  TGTGCATGAT  420
421   GACATCCTCA  TTGCCCAGCT  ACGTCCTGGT  CAGGAGCTTG  ATCTACTGAT  GCATTGTGTC  480
481   AAAGGCATTG  GCAAAGATCA  TGCTAAGTTT  TCTCCTGTGG  CTACTGCTAG  TTACAGATTA  540
541   TTGCCAGATA  TTACTCTGTT  ACAGCCAATA  GAAGGGGAAG  CAGCTGAGGA  ACTGAGTCAA  600
601   TGCTTTTCAC  CTGGTGTCAT  TCAGGTGCAA  GATGTTAAAG  GAAAAAAAGT  AGCCACAGTT  660
661   GCCAACCCCC  GGCTGGATAC  CTTCAGTAGA  GAGATCTTTC  GGCATGAGAA  CCTTAAGAAA  720
721   CTGGTGAGGC  TGGCCCGAGT  ACGGGATCAC  TACATATTCT  CAGTGGAGTC  AACAGGTGTC  780
781   TTGCCCCCTG  AGGTCCTGGT  GAGTGAAGCC  ATCAAAGTCC  TAATGGGAAA  ATGTCGGCGC  840
841   TTCATGGATG  AATTGGATTC  AGTTCAGATG  GACTAA  876

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sah-1950Sarcophilus harrisii96.990.0 540
LLPS-Paa-2288Papio anubis92.10.0 566
LLPS-Mal-0572Mandrillus leucophaeus92.10.0 566
LLPS-Cea-1040Cercocebus atys92.10.0 566
LLPS-Maf-0562Macaca fascicularis91.750.0 565
LLPS-Ict-1899Ictidomys tridecemlineatus91.750.0 565
LLPS-Mam-3012Macaca mulatta91.750.0 565
LLPS-Orc-0384Oryctolagus cuniculus91.750.0 563
LLPS-Man-0396Macaca nemestrina91.750.0 565
LLPS-Ere-0166Erinaceus europaeus91.410.0 565
LLPS-Gog-0513Gorilla gorilla91.410.0 563
LLPS-Chs-2325Chlorocebus sabaeus91.410.0 564
LLPS-Nol-0421Nomascus leucogenys91.410.0 563
LLPS-Hos-2159Homo sapiens91.410.0 563
LLPS-Pat-0287Pan troglodytes91.410.0 563
LLPS-Pap-0728Pan paniscus91.410.0 563
LLPS-Mup-1468Mustela putorius furo91.070.0 561
LLPS-Aon-0025Aotus nancymaae91.070.0 563
LLPS-Poa-2772Pongo abelii91.070.0 561
LLPS-Rhb-1174Rhinopithecus bieti91.070.0 563
LLPS-Caj-1804Callithrix jacchus90.720.0 561
LLPS-Cas-0060Carlito syrichta90.380.0 558
LLPS-Cap-0472Cavia porcellus90.380.0 559
LLPS-Myl-0961Myotis lucifugus90.030.0 558
LLPS-Fud-1041Fukomys damarensis90.030.0 555
LLPS-Loa-0181Loxodonta africana89.730.0 552
LLPS-Dio-0379Dipodomys ordii89.690.0 556
LLPS-Caf-1355Canis familiaris89.690.0 557
LLPS-Fec-1689Felis catus89.690.0 556
LLPS-Urm-0152Ursus maritimus89.690.0 555
LLPS-Aim-2483Ailuropoda melanoleuca89.350.0 554
LLPS-Ova-0751Ovis aries89.350.0 554
LLPS-Mea-0280Mesocricetus auratus89.350.0 555
LLPS-Eqc-1243Equus caballus89.350.0 556
LLPS-Ran-1242Rattus norvegicus89.00.0 553
LLPS-Bot-0027Bos taurus89.00.0 553
LLPS-Sus-0094Sus scrofa89.00.0 552
LLPS-Mum-0072Mus musculus89.00.0 553
LLPS-Otg-1631Otolemur garnettii88.40.0 551
LLPS-Ora-0078Ornithorhynchus anatinus87.630.0 547
LLPS-Anp-0491Anas platyrhynchos85.660.0 527
LLPS-Pes-0148Pelodiscus sinensis85.570.0 534
LLPS-Fia-0926Ficedula albicollis84.720.0 525
LLPS-Gaga-0717Gallus gallus84.480.0 528
LLPS-Tag-0989Taeniopygia guttata84.140.0 526
LLPS-Anc-0838Anolis carolinensis81.752e-150 433
LLPS-Meg-0890Meleagris gallopavo80.072e-177 498
LLPS-Xet-0786Xenopus tropicalis78.083e-169 480
LLPS-Leo-0342Lepisosteus oculatus77.442e-156 449
LLPS-Scf-0423Scleropages formosus77.322e-173 491
LLPS-Asm-0135Astyanax mexicanus76.291e-171 486
LLPS-Icp-1707Ictalurus punctatus76.127e-170 482
LLPS-Dar-1172Danio rerio75.524e-168 478
LLPS-Orn-1493Oreochromis niloticus74.243e-161 461
LLPS-Scm-0841Scophthalmus maximus74.237e-165 469
LLPS-Pof-0330Poecilia formosa73.563e-164 468
LLPS-Xim-2365Xiphophorus maculatus73.229e-164 466
LLPS-Tar-0813Takifugu rubripes72.114e-162 462
LLPS-Orl-0725Oryzias latipes71.823e-159 455
LLPS-Ten-0112Tetraodon nigroviridis70.871e-60 195
LLPS-Gaa-0094Gasterosteus aculeatus66.882e-154 444
LLPS-Lac-0286Latimeria chalumnae65.641e-130 381
LLPS-Cii-0396Ciona intestinalis58.131e-121 359
LLPS-Drm-0991Drosophila melanogaster57.494e-119 352
LLPS-Abg-0941Absidia glauca56.947e-117 347
LLPS-Pug-0074Puccinia graminis54.299e-101 306
LLPS-Spr-0186Sporisorium reilianum53.062e-108 327
LLPS-Tum-0270Tuber melanosporum52.53e-95 293
LLPS-Usm-0914Ustilago maydis52.385e-106 321
LLPS-Scp-0341Schizosaccharomyces pombe51.697e-101 306
LLPS-Put-0184Puccinia triticina51.195e-97 297
LLPS-Thc-1546Theobroma cacao51.166e-90 279
LLPS-Mel-0232Melampsora laricipopulina51.041e-98 301
LLPS-Scj-0024Schizosaccharomyces japonicus50.881e-94 290
LLPS-Sol-0491Solanum lycopersicum50.832e-88 276
LLPS-Gor-0314Gossypium raimondii50.835e-92 282
LLPS-Crn-0311Cryptococcus neoformans50.72e-102 310
LLPS-Sot-0477Solanum tuberosum50.59e-89 276
LLPS-Nia-1512Nicotiana attenuata50.55e-88 275
LLPS-Arl-0327Arabidopsis lyrata50.341e-85 268
LLPS-Mae-0069Manihot esculenta50.179e-89 276
LLPS-Viv-1197Vitis vinifera50.01e-88 275
LLPS-Sem-1665Selaginella moellendorffii49.834e-87 271
LLPS-Asfu-0587Aspergillus fumigatus49.674e-93 287
LLPS-Amt-0638Amborella trichopoda49.577e-66 215
LLPS-Cae-0103Caenorhabditis elegans49.52e-98 300
LLPS-Asni-0319Aspergillus niger49.471e-91 283
LLPS-Glm-0244Glycine max49.332e-86 271
LLPS-Nef-0319Neosartorya fischeri49.337e-93 286
LLPS-Ast-0099Aspergillus terreus49.333e-90 280
LLPS-Asf-0377Aspergillus flavus49.161e-92 286
LLPS-Aso-0670Aspergillus oryzae49.161e-92 286
LLPS-Coc-0546Corchorus capsularis49.163e-86 270
LLPS-Scc-0753Schizosaccharomyces cryophilus49.152e-96 295
LLPS-Art-1854Arabidopsis thaliana49.151e-80 255
LLPS-Sac-0408Saccharomyces cerevisiae48.751e-95 292
LLPS-Via-1077Vigna angularis48.332e-84 265
LLPS-Asc-0155Aspergillus clavatus48.332e-91 283
LLPS-Php-0183Physcomitrella patens48.187e-92 283
LLPS-Asn-0130Aspergillus nidulans47.833e-92 285
LLPS-Vir-0430Vigna radiata47.674e-83 262
LLPS-Mua-1653Musa acuminata47.653e-83 261
LLPS-Lep-0216Leersia perrieri47.645e-77 246
LLPS-Brn-0268Brassica napus47.69e-81 256
LLPS-Coo-0821Colletotrichum orbiculare47.563e-92 285
LLPS-Asg-0057Ashbya gossypii47.55e-91 281
LLPS-Cus-0001Cucumis sativus47.454e-81 257
LLPS-Pytr-0600Pyrenophora triticirepentis47.441e-88 276
LLPS-Phn-0236Phaeosphaeria nodorum47.256e-89 276
LLPS-Chc-0227Chondrus crispus47.144e-78 249
LLPS-Hov-0047Hordeum vulgare47.121e-77 248
LLPS-Cogr-1107Colletotrichum graminicola47.069e-91 281
LLPS-Gas-0006Galdieria sulphuraria46.964e-68 220
LLPS-Pot-0647Populus trichocarpa46.951e-87 274
LLPS-Brr-0686Brassica rapa46.895e-82 259
LLPS-Tra-1682Triticum aestivum46.782e-78 248
LLPS-Zem-0476Zea mays46.782e-78 249
LLPS-Nec-1035Neurospora crassa46.673e-88 275
LLPS-Phv-0517Phaseolus vulgaris46.677e-82 258
LLPS-Brd-0536Brachypodium distachyon46.62e-77 246
LLPS-Fus-0797Fusarium solani46.552e-78 249
LLPS-Bro-0336Brassica oleracea46.516e-81 256
LLPS-Orp-0434Oryza punctata46.513e-75 241
LLPS-Kop-0270Komagataella pastoris46.43e-88 273
LLPS-Lem-1225Leptosphaeria maculans46.285e-85 266
LLPS-Sob-0988Sorghum bicolor45.935e-80 253
LLPS-Hea-1070Helianthus annuus45.811e-82 260
LLPS-Cog-0270Colletotrichum gloeosporioides45.758e-87 271
LLPS-Scs-0086Sclerotinia sclerotiorum45.699e-86 269
LLPS-Ved-0373Verticillium dahliae45.672e-83 262
LLPS-Miv-0052Microbotryum violaceum45.551e-82 259
LLPS-Orbr-0191Oryza brachyantha45.516e-75 240
LLPS-Tru-0886Triticum urartu45.452e-72 245
LLPS-Prp-1946Prunus persica45.253e-82 260
LLPS-Map-0655Magnaporthe poae45.122e-80 255
LLPS-Ori-0111Oryza indica45.122e-73 236
LLPS-Blg-0148Blumeria graminis45.082e-78 249
LLPS-Zyt-0168Zymoseptoria tritici44.838e-82 261
LLPS-Pyt-0261Pyrenophora teres44.797e-86 269
LLPS-Orgl-1779Oryza glumaepatula44.631e-71 235
LLPS-Orni-0930Oryza nivara44.638e-73 235
LLPS-Orb-0910Oryza barthii44.638e-73 235
LLPS-Org-0040Oryza glaberrima44.639e-73 235
LLPS-Orr-0273Oryza rufipogon44.638e-73 235
LLPS-Ors-0914Oryza sativa44.636e-73 235
LLPS-Fuv-0112Fusarium verticillioides44.481e-75 242
LLPS-Fuo-0562Fusarium oxysporum44.486e-76 243
LLPS-Beb-0575Beauveria bassiana44.372e-78 250
LLPS-Mao-0872Magnaporthe oryzae44.162e-83 262
LLPS-Gag-0275Gaeumannomyces graminis44.114e-80 254
LLPS-Trr-0337Trichoderma reesei43.882e-75 242
LLPS-Sei-0057Setaria italica43.831e-76 244
LLPS-Dos-0046Dothistroma septosporum43.564e-80 254
LLPS-Trv-0347Trichoderma virens43.544e-75 241
LLPS-Yal-0044Yarrowia lipolytica43.452e-71 230
LLPS-Met-1180Medicago truncatula42.323e-77 247
LLPS-Dac-0023Daucus carota40.835e-59 196
LLPS-Osl-0622Ostreococcus lucimarinus39.553e-69 225
LLPS-Chr-0173Chlamydomonas reinhardtii36.873e-59 200
LLPS-Cym-0628Cyanidioschyzon merolae31.232e-39 147