LLPS-Ors-2334
ORC4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Origin of replication complex subunit 4 |
| Gene Name: | ORC4, LOC_Os01g49010, Os01g0683400, OsJ_03032, P0445E10.9 |
| Ensembl Gene: | Os01g0683400 |
| Ensembl Protein: | Os01t0683400-01 |
| Organism: | Oryza sativa |
| Taxa ID: | 39947 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Os01t0683400-01 | Os01t0683400-01 |
| UniProt | Q5N8Q4, ORC4_ORYSJ, A0A0P0V6N4, B9EYM5, Q7Y0X0 | |
| GeneBank | CM000138, AP003347, AP008207, AP014957, AK102997, AB110983 | BAD82152.1, BAC77041.1, BAF05802.1, BAG95826.1, EEE55188.1, BAS73726.1 |
| RefSeq | XM_015757442.1, XM_015757449.1 | XP_015612928.1, XP_015612935.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAAAAAASV ASQAQAVLRG RLCDQAVVHS ALRSSPDTNY SKLKYLVASS VSEACNNSVL 60 61 LLGPRGCGKA AVRFSFLVYS SAPLSAVFSD AGVVFDEMCQ WAIYDFTLWV VSAWTEVVDM 120 121 VLDDLKKDHP DAISVIRLNG MLHSDDNCAT KEIARQLCLE HQLSFSKMAS SDDNTEFMID 180 181 MLRECGLAHK TIIFVLEEFD LFAQGKQRLL YSLLDAMQSL TSQAVVIGVS CRLDADQLLE 240 241 KRVRSRFSHR KLLFVPSSVD SLQRLMEHLL ALPEDSPLPT KYVREYNARI TSIFNDKKFK 300 301 GILSSLTDAD ATTSHILRFL FRVVSYMDID SGLLSMQSFM NALSSMQRQP KMDSLQDLSI 360 361 LELYILVCMN RLEDKEKSSY NFITIMKEYK SVQDAYKTSD KYSHTVCFRA FEHLLDRELI 420 421 SFADNKGRNQ ALEYRPVKLL ISSRELAESL KLNTTCPAVL QKLLDRERYM 470 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCGG CGGCGGCGGC TGCGTCCGTG GCGAGTCAAG CGCAGGCCGT GCTCCGCGGC 60 61 AGGCTCTGCG ACCAGGCCGT CGTCCACTCC GCCCTCAGGT CCTCGCCGGA CACCAACTAC 120 121 AGTAAGCTGA AGTACCTCGT CGCCAGCTCC GTCTCCGAAG CCTGCAACAA CTCCGTCCTA 180 181 CTCCTCGGCC CCCGCGGCTG CGGAAAAGCC GCGGTGAGGT TTTCCTTCCT AGTATACTCT 240 241 TCTGCCCCAC TTTCAGCGGT TTTCTCGGAT GCGGGGGTGG TGTTCGACGA AATGTGCCAG 300 301 TGGGCGATCT ACGACTTTAC GCTATGGGTT GTTTCGGCAT GGACTGAGGT GGTCGACATG 360 361 GTTCTAGATG ATCTGAAGAA GGATCATCCT GATGCAATAT CAGTGATCAG GCTGAATGGG 420 421 ATGCTACATA GTGATGACAA CTGTGCCACG AAGGAAATTG CGAGGCAACT TTGTTTGGAA 480 481 CATCAGTTAT CATTTTCCAA AATGGCTTCT TCAGATGACA ACACGGAATT CATGATTGAC 540 541 ATGTTACGGG AGTGTGGACT AGCTCACAAG ACAATAATTT TTGTCCTAGA AGAGTTTGAC 600 601 CTCTTTGCTC AGGGGAAGCA GAGGTTACTC TATAGCTTAC TTGATGCAAT GCAATCTCTC 660 661 ACCTCACAAG CTGTTGTTAT TGGTGTGAGT TGCCGATTGG ATGCAGACCA ACTCCTAGAG 720 721 AAAAGGGTTA GATCCCGGTT CTCTCATAGG AAGCTTCTGT TTGTTCCTTC TTCAGTGGAT 780 781 AGTTTACAGA GGTTAATGGA GCACTTGCTA GCACTTCCTG AAGATTCTCC CTTACCAACA 840 841 AAGTATGTCA GGGAGTACAA TGCACGGATT ACTAGCATTT TCAATGACAA AAAGTTCAAA 900 901 GGAATTCTCA GCTCCCTCAC TGATGCTGAC GCAACAACAA GCCACATCCT TAGATTTCTT 960 961 TTCAGAGTGG TGTCATACAT GGACATAGAT TCTGGACTTC TGTCAATGCA AAGCTTCATG 1020 1021 AATGCGCTAT CTTCGATGCA GAGGCAGCCT AAGATGGACA GTTTGCAAGA TCTCTCCATT 1080 1081 TTGGAACTAT ACATTCTTGT ATGCATGAAC AGGCTAGAAG ATAAGGAGAA AAGTTCATAC 1140 1141 AACTTTATCA CTATTATGAA AGAGTACAAA TCTGTGCAGG ATGCCTACAA AACGTCGGAC 1200 1201 AAATATTCAC ACACTGTTTG TTTTAGAGCT TTTGAGCATC TTTTGGATCG CGAGTTGATT 1260 1261 AGCTTTGCAG ACAACAAAGG GAGAAATCAG GCGCTTGAAT ATCGTCCTGT CAAACTTCTG 1320 1321 ATATCTTCAC GTGAGCTTGC TGAGTCCCTC AAGTTGAACA CGACCTGCCC TGCTGTTTTG 1380 1381 CAGAAGCTTC TTGACCGTGA AAGATACATG TAA 1413 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nuclear origin of replication recognition complex | |
Molecular Function | ATP binding | |
Molecular Function | DNA replication origin binding | |
Biological Process | DNA replication initiation | |
Biological Process | Response to sucrose |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Org-2096 | Oryza glaberrima | 100.0 | 0.0 | 902 |
| LLPS-Orm-0364 | Oryza meridionalis | 90.29 | 0.0 | 808 |
| LLPS-Orgl-1862 | Oryza glumaepatula | 89.85 | 0.0 | 806 |
| LLPS-Hov-1227 | Hordeum vulgare | 88.92 | 0.0 | 625 |
| LLPS-Orp-1564 | Oryza punctata | 88.3 | 0.0 | 786 |
| LLPS-Orni-0496 | Oryza nivara | 84.33 | 0.0 | 743 |
| LLPS-Orbr-1711 | Oryza brachyantha | 83.66 | 0.0 | 757 |
| LLPS-Orb-0835 | Oryza barthii | 80.35 | 0.0 | 693 |
| LLPS-Orr-2114 | Oryza rufipogon | 80.35 | 0.0 | 693 |
| LLPS-Tra-1053 | Triticum aestivum | 79.69 | 0.0 | 715 |
| LLPS-Ori-1934 | Oryza indica | 79.69 | 0.0 | 688 |
| LLPS-Brd-0755 | Brachypodium distachyon | 78.15 | 0.0 | 695 |
| LLPS-Sei-0444 | Setaria italica | 77.92 | 0.0 | 707 |
| LLPS-Sob-2517 | Sorghum bicolor | 77.26 | 0.0 | 703 |
| LLPS-Hea-1679 | Helianthus annuus | 68.52 | 3e-16 | 84.7 |
| LLPS-Dac-0695 | Daucus carota | 67.92 | 1e-14 | 80.9 |
| LLPS-Zem-2305 | Zea mays | 66.13 | 0.0 | 615 |
| LLPS-Cus-0275 | Cucumis sativus | 62.91 | 2e-156 | 458 |
| LLPS-Mua-2394 | Musa acuminata | 62.39 | 0.0 | 565 |
| LLPS-Met-1079 | Medicago truncatula | 62.24 | 8e-154 | 451 |
| LLPS-Vir-1994 | Vigna radiata | 60.74 | 8e-145 | 431 |
| LLPS-Coc-0688 | Corchorus capsularis | 59.71 | 2e-105 | 321 |
| LLPS-Viv-0381 | Vitis vinifera | 59.02 | 0.0 | 524 |
| LLPS-Prp-0795 | Prunus persica | 58.31 | 0.0 | 531 |
| LLPS-Nia-2139 | Nicotiana attenuata | 58.13 | 0.0 | 530 |
| LLPS-Thc-0030 | Theobroma cacao | 58.0 | 3e-179 | 516 |
| LLPS-Gor-0994 | Gossypium raimondii | 57.91 | 0.0 | 521 |
| LLPS-Sot-0450 | Solanum tuberosum | 57.81 | 0.0 | 522 |
| LLPS-Pot-1534 | Populus trichocarpa | 57.6 | 2e-177 | 511 |
| LLPS-Bro-2044 | Brassica oleracea | 56.47 | 0.0 | 523 |
| LLPS-Brn-1010 | Brassica napus | 56.1 | 2e-178 | 514 |
| LLPS-Via-1169 | Vigna angularis | 55.78 | 3e-172 | 498 |
| LLPS-Phv-1462 | Phaseolus vulgaris | 55.56 | 1e-170 | 494 |
| LLPS-Mae-0549 | Manihot esculenta | 55.36 | 9e-176 | 507 |
| LLPS-Amt-1290 | Amborella trichopoda | 54.91 | 5e-153 | 449 |
| LLPS-Arl-1682 | Arabidopsis lyrata | 54.65 | 2e-171 | 498 |
| LLPS-Glm-0146 | Glycine max | 54.44 | 2e-163 | 475 |
| LLPS-Tru-1259 | Triticum urartu | 53.52 | 4e-130 | 388 |
| LLPS-Brr-2296 | Brassica rapa | 51.09 | 1e-158 | 463 |
| LLPS-Sol-0622 | Solanum lycopersicum | 50.23 | 1e-124 | 395 |
| LLPS-Php-1886 | Physcomitrella patens | 43.17 | 6e-115 | 352 |
| LLPS-Chr-1128 | Chlamydomonas reinhardtii | 41.94 | 7e-20 | 96.7 |
| LLPS-Coo-0802 | Colletotrichum orbiculare | 39.29 | 6e-18 | 90.9 |
| LLPS-Dos-1339 | Dothistroma septosporum | 39.07 | 3e-18 | 89.7 |
| LLPS-Beb-1255 | Beauveria bassiana | 37.8 | 5e-18 | 91.3 |
| LLPS-Scj-1129 | Schizosaccharomyces japonicus | 35.26 | 8e-22 | 102 |
| LLPS-Icp-2131 | Ictalurus punctatus | 33.23 | 3e-41 | 157 |
| LLPS-Asm-4055 | Astyanax mexicanus | 32.32 | 8e-39 | 151 |
| LLPS-Zyt-1527 | Zymoseptoria tritici | 32.3 | 2e-23 | 107 |
| LLPS-Ora-3016 | Ornithorhynchus anatinus | 32.22 | 3e-38 | 149 |
| LLPS-Asni-1602 | Aspergillus niger | 31.91 | 1e-21 | 102 |
| LLPS-Gaa-3488 | Gasterosteus aculeatus | 31.64 | 6e-38 | 148 |
| LLPS-Asn-1277 | Aspergillus nidulans | 31.49 | 2e-20 | 99.0 |
| LLPS-Cii-2211 | Ciona intestinalis | 31.4 | 8e-40 | 153 |
| LLPS-Ict-1881 | Ictidomys tridecemlineatus | 31.1 | 3e-38 | 149 |
| LLPS-Scc-1116 | Schizosaccharomyces cryophilus | 31.07 | 5e-15 | 82.0 |
| LLPS-Nef-1026 | Neosartorya fischeri | 31.03 | 3e-21 | 100 |
| LLPS-Mao-1501 | Magnaporthe oryzae | 30.94 | 4e-21 | 100 |
| LLPS-Lac-3445 | Latimeria chalumnae | 30.63 | 3e-39 | 150 |
| LLPS-Crn-1250 | Cryptococcus neoformans | 30.5 | 2e-10 | 67.4 |
| LLPS-Asc-1560 | Aspergillus clavatus | 30.21 | 3e-21 | 100 |
| LLPS-Asfu-1407 | Aspergillus fumigatus | 30.21 | 2e-21 | 101 |
| LLPS-Ast-0576 | Aspergillus terreus | 30.21 | 2e-20 | 98.6 |
| LLPS-Ved-1543 | Verticillium dahliae | 30.11 | 5e-25 | 112 |
| LLPS-Cea-0028 | Cercocebus atys | 30.1 | 1e-25 | 111 |
| LLPS-Gag-0117 | Gaeumannomyces graminis | 30.09 | 8e-21 | 99.8 |
| LLPS-Dar-3607 | Danio rerio | 30.07 | 1e-47 | 176 |
| LLPS-Pytr-1194 | Pyrenophora triticirepentis | 29.96 | 5e-18 | 90.9 |
| LLPS-Ten-2830 | Tetraodon nigroviridis | 29.91 | 2e-42 | 161 |
| LLPS-Miv-1381 | Microbotryum violaceum | 29.82 | 5e-13 | 75.9 |
| LLPS-Pes-1405 | Pelodiscus sinensis | 29.79 | 3e-37 | 146 |
| LLPS-Cis-1935 | Ciona savignyi | 29.71 | 4e-38 | 149 |
| LLPS-Abg-1770 | Absidia glauca | 29.65 | 2e-30 | 125 |
| LLPS-Xim-3036 | Xiphophorus maculatus | 29.62 | 1e-41 | 159 |
| LLPS-Pyt-1415 | Pyrenophora teres | 29.54 | 1e-17 | 89.7 |
| LLPS-Leo-3351 | Lepisosteus oculatus | 29.49 | 1e-45 | 170 |
| LLPS-Kop-0640 | Komagataella pastoris | 29.47 | 3e-16 | 85.5 |
| LLPS-Yal-0609 | Yarrowia lipolytica | 29.28 | 1e-14 | 80.1 |
| LLPS-Scm-3348 | Scophthalmus maximus | 29.24 | 1e-29 | 124 |
| LLPS-Pof-1529 | Poecilia formosa | 29.18 | 5e-44 | 166 |
| LLPS-Anp-0728 | Anas platyrhynchos | 28.95 | 8e-41 | 156 |
| LLPS-Tar-2482 | Takifugu rubripes | 28.87 | 5e-32 | 132 |
| LLPS-Ova-4311 | Ovis aries | 28.86 | 1e-41 | 160 |
| LLPS-Phn-1104 | Phaeosphaeria nodorum | 28.81 | 2e-18 | 92.4 |
| LLPS-Gaga-1908 | Gallus gallus | 28.79 | 6e-41 | 158 |
| LLPS-Map-1177 | Magnaporthe poae | 28.76 | 6e-20 | 97.4 |
| LLPS-Lem-1441 | Leptosphaeria maculans | 28.75 | 3e-18 | 92.0 |
| LLPS-Xet-0988 | Xenopus tropicalis | 28.74 | 3e-33 | 134 |
| LLPS-Meg-3214 | Meleagris gallopavo | 28.67 | 2e-40 | 155 |
| LLPS-Bot-3067 | Bos taurus | 28.64 | 6e-41 | 157 |
| LLPS-Mea-2812 | Mesocricetus auratus | 28.64 | 4e-43 | 163 |
| LLPS-Nec-1288 | Neurospora crassa | 28.57 | 3e-19 | 95.1 |
| LLPS-Fia-0673 | Ficedula albicollis | 28.57 | 1e-31 | 129 |
| LLPS-Orl-1768 | Oryzias latipes | 28.51 | 1e-38 | 150 |
| LLPS-Orn-3268 | Oreochromis niloticus | 28.48 | 2e-39 | 152 |
| LLPS-Cas-2142 | Carlito syrichta | 28.41 | 3e-39 | 152 |
| LLPS-Fud-2489 | Fukomys damarensis | 28.35 | 3e-38 | 149 |
| LLPS-Scf-2197 | Scleropages formosus | 28.29 | 2e-41 | 158 |
| LLPS-Asf-1018 | Aspergillus flavus | 28.23 | 1e-21 | 102 |
| LLPS-Tag-0684 | Taeniopygia guttata | 28.19 | 7e-39 | 150 |
| LLPS-Mod-4101 | Monodelphis domestica | 28.12 | 4e-39 | 152 |
| LLPS-Spr-1172 | Sporisorium reilianum | 28.1 | 1e-16 | 86.7 |
| LLPS-Aso-1100 | Aspergillus oryzae | 28.09 | 3e-22 | 103 |
| LLPS-Dio-3883 | Dipodomys ordii | 28.03 | 1e-38 | 150 |
| LLPS-Usm-0663 | Ustilago maydis | 27.94 | 2e-18 | 92.8 |
| LLPS-Scp-1546 | Schizosaccharomyces pombe | 27.93 | 1e-20 | 99.4 |
| LLPS-Drm-2291 | Drosophila melanogaster | 27.88 | 3e-37 | 147 |
| LLPS-Myl-2207 | Myotis lucifugus | 27.8 | 3e-39 | 152 |
| LLPS-Anc-0548 | Anolis carolinensis | 27.8 | 1e-40 | 156 |
| LLPS-Fec-0510 | Felis catus | 27.8 | 4e-39 | 152 |
| LLPS-Tut-2064 | Tursiops truncatus | 27.74 | 4e-40 | 154 |
| LLPS-Ran-4743 | Rattus norvegicus | 27.74 | 5e-38 | 149 |
| LLPS-Sus-1848 | Sus scrofa | 27.74 | 6e-39 | 151 |
| LLPS-Asg-1501 | Ashbya gossypii | 27.65 | 1e-12 | 73.9 |
| LLPS-Mup-3691 | Mustela putorius furo | 27.58 | 1e-39 | 153 |
| LLPS-Mal-0902 | Mandrillus leucophaeus | 27.58 | 4e-39 | 152 |
| LLPS-Paa-2941 | Papio anubis | 27.58 | 3e-39 | 152 |
| LLPS-Chs-4728 | Chlorocebus sabaeus | 27.58 | 2e-39 | 152 |
| LLPS-Gog-0563 | Gorilla gorilla | 27.58 | 1e-39 | 153 |
| LLPS-Eqc-2657 | Equus caballus | 27.58 | 5e-40 | 154 |
| LLPS-Nol-1167 | Nomascus leucogenys | 27.58 | 1e-39 | 153 |
| LLPS-Hos-4182 | Homo sapiens | 27.58 | 2e-39 | 152 |
| LLPS-Urm-3198 | Ursus maritimus | 27.58 | 2e-39 | 152 |
| LLPS-Pap-1707 | Pan paniscus | 27.58 | 2e-39 | 152 |
| LLPS-Gas-0364 | Galdieria sulphuraria | 27.54 | 1e-21 | 101 |
| LLPS-Aim-3147 | Ailuropoda melanoleuca | 27.35 | 9e-39 | 150 |
| LLPS-Sah-1207 | Sarcophilus harrisii | 27.35 | 2e-40 | 155 |
| LLPS-Aon-2259 | Aotus nancymaae | 27.35 | 2e-38 | 149 |
| LLPS-Maf-1136 | Macaca fascicularis | 27.35 | 5e-39 | 151 |
| LLPS-Caj-4451 | Callithrix jacchus | 27.35 | 7e-38 | 148 |
| LLPS-Mam-2816 | Macaca mulatta | 27.35 | 5e-39 | 151 |
| LLPS-Man-0838 | Macaca nemestrina | 27.35 | 5e-39 | 151 |
| LLPS-Pat-3153 | Pan troglodytes | 27.35 | 8e-39 | 150 |
| LLPS-Orc-3149 | Oryctolagus cuniculus | 27.35 | 2e-39 | 153 |
| LLPS-Otg-2483 | Otolemur garnettii | 27.35 | 6e-40 | 154 |
| LLPS-Poa-3891 | Pongo abelii | 27.13 | 6e-39 | 151 |
| LLPS-Mum-0895 | Mus musculus | 27.07 | 4e-38 | 149 |
| LLPS-Cogr-1657 | Colletotrichum graminicola | 27.03 | 6e-22 | 103 |
| LLPS-Loa-3065 | Loxodonta africana | 27.03 | 1e-39 | 153 |
| LLPS-Caf-3287 | Canis familiaris | 26.93 | 1e-38 | 150 |
| LLPS-Cap-4545 | Cavia porcellus | 26.74 | 3e-35 | 140 |
| LLPS-Rhb-4249 | Rhinopithecus bieti | 26.74 | 2e-37 | 147 |
| LLPS-Tum-1616 | Tuber melanosporum | 26.33 | 1e-15 | 82.8 |
| LLPS-Trr-0297 | Trichoderma reesei | 26.19 | 1e-24 | 111 |
| LLPS-Cog-0931 | Colletotrichum gloeosporioides | 25.72 | 3e-21 | 101 |
| LLPS-Trv-1590 | Trichoderma virens | 25.17 | 6e-22 | 102 |
| LLPS-Fuv-0439 | Fusarium verticillioides | 25.11 | 3e-24 | 109 |
| LLPS-Fuo-1009 | Fusarium oxysporum | 25.11 | 3e-23 | 107 |
| LLPS-Sac-0983 | Saccharomyces cerevisiae | 25.08 | 5e-07 | 56.2 |
| LLPS-Blg-1531 | Blumeria graminis | 25.0 | 7e-22 | 103 |
| LLPS-Fus-1556 | Fusarium solani | 24.51 | 8e-23 | 105 |