• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orn-0180
cct7

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: T-complex protein 1 subunit eta
Gene Name: cct7
Ensembl Gene: ENSONIG00000013565.1
Ensembl Protein: ENSONIP00000017057.1
Organism: Oreochromis niloticus
Taxa ID: 8128
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSONIT00000017072.1ENSONIP00000017057.1
UniProtI3K7G2, I3K7G2_ORENI
GeneBankAERX01028352

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLSKSILGSD  AGGKLLERTA  KMMPTPVILL  KEGTDTSQGI  PQLISNINAC  QVIAEAVRTT  60
61    LGPRGMDKLM  VDSRGKATIS  NDGATILKLL  DVVHPAAKTL  VDIARSQDAE  VGDGTTSVTL  120
121   LAAEFLKQLK  SYVEEGLHPQ  TIIRAFRTAT  NLAVSKIKEI  AVSVKKDDKQ  EQRELLEKCA  180
181   ATALNSKLIA  GQKEFFSKMV  VDAVMSLEEL  MSLKMIGIKK  VQGGALEESQ  LVSGVAFKKT  240
241   FSYAGFEMQP  KRYENPKIAL  LNVELELKAE  KDNAEVRVKS  VEDYQAIVDA  EWNILYDKLE  300
301   KIYQSGAKVV  LSKLPIGDVA  TQFFADRDLF  CAGRVQEEDL  KRTMMACGGS  IQTSVGAMTD  360
361   DVLGQCELFE  EVQVGGERYN  FFKGCPKAKT  CTIILRGGAE  QFTEETERSL  HDAIMIVRRA  420
421   IKNDSVVAGG  GAIEMELSKY  LRDYSRTIPG  KQQLLIGAYA  KALEIIPRQL  CDNAGFDATN  480
481   ILNKLRAKHA  QGGMWYGVDI  NNEDIADNFV  ACVWEPSIVR  INALTAASEA  ACLILSVDET  540
541   IKNPRSTMDG  PPGGAGRGRG  RGRPHAH  567
Nucleotide CDS Sequence (FASTA)
1     ATGCTTTCGA  AAAGCATTCT  GGGATCCGAT  GCCGGTGGAA  AGCTTCTCGA  AAGAACTGCA  60
61    AAGATGATGC  CCACACCGGT  TATCCTGCTT  AAGGAGGGGA  CGGACACATC  TCAGGGCATT  120
121   CCCCAGCTCA  TCAGCAACAT  CAATGCCTGC  CAGGTGATTG  CTGAGGCTGT  CAGGACCACC  180
181   CTGGGGCCCA  GGGGGATGGA  CAAACTGATG  GTGGACAGCA  GAGGAAAGGC  CACAATCTCC  240
241   AACGATGGAG  CCACCATCCT  GAAACTGCTG  GATGTGGTTC  ACCCTGCGGC  CAAAACTCTG  300
301   GTGGACATCG  CTCGCTCCCA  GGACGCTGAG  GTTGGGGACG  GCACCACCTC  CGTCACCCTC  360
361   CTGGCTGCAG  AGTTCCTGAA  GCAGCTGAAG  TCGTATGTGG  AGGAGGGTCT  CCACCCGCAG  420
421   ACCATCATCA  GAGCGTTCCG  CACCGCCACC  AATCTCGCCG  TCAGCAAGAT  CAAGGAGATC  480
481   GCCGTCTCTG  TGAAAAAAGA  CGATAAGCAA  GAGCAGAGGG  AGCTTTTGGA  GAAATGTGCA  540
541   GCCACAGCTC  TAAACTCCAA  GCTGATCGCC  GGTCAGAAGG  AATTCTTCTC  CAAAATGGTT  600
601   GTGGATGCAG  TCATGTCACT  GGAGGAGCTC  ATGTCTCTGA  AAATGATCGG  TATCAAGAAG  660
661   GTCCAGGGAG  GAGCTCTGGA  GGAGTCCCAG  CTGGTCTCTG  GCGTTGCGTT  CAAGAAGACG  720
721   TTCTCCTACG  CCGGCTTTGA  GATGCAGCCC  AAACGCTACG  AAAATCCAAA  GATCGCTTTG  780
781   CTCAATGTGG  AGCTGGAGCT  GAAAGCCGAG  AAGGACAACG  CTGAAGTCCG  TGTGAAATCT  840
841   GTGGAGGACT  ACCAGGCCAT  CGTGGATGCA  GAGTGGAACA  TCTTATACGA  CAAGCTGGAG  900
901   AAGATCTATC  AGTCGGGAGC  CAAGGTGGTC  CTGTCAAAGT  TGCCCATCGG  TGATGTGGCC  960
961   ACCCAGTTCT  TCGCTGACAG  AGACCTGTTC  TGTGCTGGGC  GGGTTCAGGA  GGAAGACCTG  1020
1021  AAGAGGACCA  TGATGGCCTG  CGGAGGCTCC  ATCCAGACGT  CTGTAGGAGC  GATGACCGAC  1080
1081  GATGTGCTGG  GACAGTGTGA  GCTCTTTGAA  GAGGTCCAGG  TCGGAGGAGA  GAGGTACAAC  1140
1141  TTCTTTAAGG  GCTGCCCGAA  GGCAAAGACA  TGCACCATCA  TCCTGAGGGG  CGGGGCTGAG  1200
1201  CAGTTCACAG  AGGAGACGGA  GCGGTCGCTG  CACGATGCCA  TCATGATCGT  GCGCAGAGCC  1260
1261  ATCAAGAATG  ACTCTGTTGT  AGCGGGTGGA  GGTGCCATAG  AGATGGAGTT  GTCCAAGTAC  1320
1321  CTGCGGGACT  ACTCGAGGAC  CATCCCCGGA  AAACAGCAGC  TCCTGATTGG  AGCATACGCC  1380
1381  AAGGCCCTGG  AGATCATCCC  CAGACAGCTG  TGCGACAACG  CCGGCTTCGA  CGCCACAAAC  1440
1441  ATCCTGAACA  AACTGAGGGC  GAAACACGCA  CAGGGGGGCA  TGTGGTACGG  TGTGGACATC  1500
1501  AACAACGAGG  ACATCGCAGA  CAACTTTGTT  GCCTGTGTGT  GGGAGCCGTC  CATAGTGCGG  1560
1561  ATCAACGCCC  TGACGGCGGC  GTCAGAAGCA  GCTTGTCTCA  TCCTGTCGGT  CGACGAGACG  1620
1621  ATCAAGAACC  CCCGCAGCAC  TATGGATGGA  CCACCAGGTG  GCGCTGGCAG  GGGCCGAGGC  1680
1681  CGCGGGAGAC  CCCATGCTCA  CTAA  1704

▼ KEYWORD

ID
Family
ATP-binding
Chaperone
Complete proteome
Cytoplasm
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
ATP binding
Molecular Function
Unfolded protein binding
Biological Process
Protein folding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ten-1365Tetraodon nigroviridis95.640.01046
LLPS-Tar-0639Takifugu rubripes95.590.01048
LLPS-Pof-2329Poecilia formosa95.420.01050
LLPS-Xim-2361Xiphophorus maculatus95.420.01049
LLPS-Orl-0835Oryzias latipes95.070.01073
LLPS-Gaa-2195Gasterosteus aculeatus93.980.01039
LLPS-Dar-0087Danio rerio92.990.01026
LLPS-Scm-0588Scophthalmus maximus92.950.01032
LLPS-Scf-1583Scleropages formosus92.80.01024
LLPS-Asm-0781Astyanax mexicanus92.790.01034
LLPS-Meg-0725Meleagris gallopavo92.235e-139 410
LLPS-Icp-2112Ictalurus punctatus91.210.01013
LLPS-Gaga-2529Gallus gallus90.720.01003
LLPS-Leo-0283Lepisosteus oculatus90.490.01029
LLPS-Xet-0421Xenopus tropicalis90.130.0 993
LLPS-Anp-1323Anas platyrhynchos89.920.0 988
LLPS-Loa-0954Loxodonta africana89.770.0 987
LLPS-Mea-0516Mesocricetus auratus89.390.0 986
LLPS-Mum-0459Mus musculus89.390.0 988
LLPS-Ran-1934Rattus norvegicus89.390.0 986
LLPS-Mod-0404Monodelphis domestica89.250.0 985
LLPS-Cap-2497Cavia porcellus89.20.0 984
LLPS-Cas-1265Carlito syrichta89.20.0 980
LLPS-Sus-0956Sus scrofa89.20.0 986
LLPS-Fud-1165Fukomys damarensis89.20.0 986
LLPS-Bot-0510Bos taurus89.20.0 984
LLPS-Ova-1511Ovis aries89.20.0 984
LLPS-Mup-0899Mustela putorius furo89.20.0 986
LLPS-Fec-1556Felis catus89.020.0 985
LLPS-Urm-1446Ursus maritimus89.020.0 984
LLPS-Hos-0161Homo sapiens89.020.0 982
LLPS-Rhb-0986Rhinopithecus bieti89.020.0 982
LLPS-Mam-3441Macaca mulatta89.020.0 982
LLPS-Maf-2745Macaca fascicularis89.020.0 982
LLPS-Gog-2529Gorilla gorilla89.020.0 982
LLPS-Mal-0519Mandrillus leucophaeus89.020.0 983
LLPS-Sah-0212Sarcophilus harrisii88.990.0 972
LLPS-Chs-0449Chlorocebus sabaeus88.990.0 979
LLPS-Caf-1536Canis familiaris88.970.0 980
LLPS-Myl-1008Myotis lucifugus88.970.0 976
LLPS-Dio-1092Dipodomys ordii88.890.0 969
LLPS-Poa-2456Pongo abelii88.830.0 976
LLPS-Nol-1984Nomascus leucogenys88.830.0 981
LLPS-Caj-0081Callithrix jacchus88.830.0 980
LLPS-Eqc-0891Equus caballus88.640.0 980
LLPS-Aon-0456Aotus nancymaae88.640.0 979
LLPS-Man-1535Macaca nemestrina88.560.0 984
LLPS-Aim-0350Ailuropoda melanoleuca88.450.0 980
LLPS-Otg-0642Otolemur garnettii88.430.0 975
LLPS-Pap-1498Pan paniscus88.260.0 973
LLPS-Pat-0038Pan troglodytes88.260.0 973
LLPS-Paa-1628Papio anubis88.260.0 972
LLPS-Fia-0070Ficedula albicollis88.180.0 818
LLPS-Ict-0195Ictidomys tridecemlineatus88.070.0 968
LLPS-Cea-0475Cercocebus atys87.950.0 810
LLPS-Orc-1254Oryctolagus cuniculus87.880.0 970
LLPS-Anc-1227Anolis carolinensis87.810.0 895
LLPS-Lac-0944Latimeria chalumnae85.80.0 924
LLPS-Pes-1667Pelodiscus sinensis85.610.0 942
LLPS-Cii-1637Ciona intestinalis81.030.0 883
LLPS-Cis-0017Ciona savignyi80.570.0 868
LLPS-Drm-0709Drosophila melanogaster75.950.0 824
LLPS-Abg-1654Absidia glauca70.970.0 772
LLPS-Ors-0659Oryza sativa69.329e-135 402
LLPS-Php-0465Physcomitrella patens68.880.0 741
LLPS-Gor-0050Gossypium raimondii68.30.0 746
LLPS-Orgl-1297Oryza glumaepatula68.22e-158 465
LLPS-Coc-1473Corchorus capsularis68.110.0 737
LLPS-Pot-1567Populus trichocarpa67.920.0 765
LLPS-Art-0817Arabidopsis thaliana67.920.0 745
LLPS-Bro-2432Brassica oleracea67.920.0 739
LLPS-Sol-0162Solanum lycopersicum67.80.0 746
LLPS-Glm-1360Glycine max67.80.0 757
LLPS-Sem-0094Selaginella moellendorffii67.740.0 719
LLPS-Brr-1670Brassica rapa67.610.0 734
LLPS-Phv-0247Phaseolus vulgaris67.610.0 754
LLPS-Sot-0979Solanum tuberosum67.610.0 744
LLPS-Via-0456Vigna angularis67.610.0 756
LLPS-Crn-0886Cryptococcus neoformans67.550.0 751
LLPS-Thc-0521Theobroma cacao67.550.0 739
LLPS-Arl-0485Arabidopsis lyrata67.550.0 743
LLPS-Usm-0014Ustilago maydis67.480.0 739
LLPS-Nia-1786Nicotiana attenuata67.360.0 742
LLPS-Brn-0942Brassica napus67.360.0 673
LLPS-Spr-0152Sporisorium reilianum67.290.0 737
LLPS-Viv-0999Vitis vinifera67.230.0 741
LLPS-Mae-0234Manihot esculenta67.170.0 736
LLPS-Dac-0407Daucus carota67.170.0 739
LLPS-Met-0289Medicago truncatula67.170.0 756
LLPS-Tum-0533Tuber melanosporum67.050.0 736
LLPS-Vir-1446Vigna radiata66.920.0 751
LLPS-Mua-0680Musa acuminata66.860.0 741
LLPS-Scp-0202Schizosaccharomyces pombe66.860.0 724
LLPS-Kop-0150Komagataella pastoris66.860.0 716
LLPS-Amt-0862Amborella trichopoda66.790.0 734
LLPS-Prp-0260Prunus persica66.790.0 733
LLPS-Cus-1518Cucumis sativus66.790.0 738
LLPS-Hea-2362Helianthus annuus66.60.0 733
LLPS-Sob-0399Sorghum bicolor66.480.0 737
LLPS-Sei-0952Setaria italica66.480.0 734
LLPS-Hov-0251Hordeum vulgare66.410.0 726
LLPS-Brd-0145Brachypodium distachyon66.350.0 731
LLPS-Lep-0839Leersia perrieri66.290.0 734
LLPS-Gas-0082Galdieria sulphuraria66.220.0 737
LLPS-Zem-0364Zea mays66.160.0 733
LLPS-Orbr-1216Oryza brachyantha66.10.0 734
LLPS-Org-0250Oryza glaberrima66.10.0 735
LLPS-Orb-1303Oryza barthii66.10.0 735
LLPS-Orni-0180Oryza nivara66.10.0 735
LLPS-Tra-1559Triticum aestivum66.10.0 726
LLPS-Pyt-0096Pyrenophora teres66.034e-177 513
LLPS-Orp-0708Oryza punctata65.910.0 731
LLPS-Yal-0963Yarrowia lipolytica65.580.0 711
LLPS-Ori-0589Oryza indica65.530.0 718
LLPS-Cae-0128Caenorhabditis elegans65.520.0 733
LLPS-Miv-0637Microbotryum violaceum65.470.0 741
LLPS-Scj-0383Schizosaccharomyces japonicus65.330.0 707
LLPS-Scc-0195Schizosaccharomyces cryophilus64.940.0 709
LLPS-Trv-0614Trichoderma virens64.570.0 699
LLPS-Mel-0617Melampsora laricipopulina64.390.0 712
LLPS-Asg-0536Ashbya gossypii64.310.0 704
LLPS-Sac-0914Saccharomyces cerevisiae64.310.0 700
LLPS-Trr-0426Trichoderma reesei64.190.0 696
LLPS-Pytr-0739Pyrenophora triticirepentis64.00.0 698
LLPS-Pug-1212Puccinia graminis63.930.0 707
LLPS-Beb-0657Beauveria bassiana63.810.0 687
LLPS-Dos-0002Dothistroma septosporum63.810.0 695
LLPS-Phn-0686Phaeosphaeria nodorum63.710.0 665
LLPS-Lem-0969Leptosphaeria maculans63.620.0 697
LLPS-Cogr-0742Colletotrichum graminicola63.430.0 695
LLPS-Coo-0535Colletotrichum orbiculare63.430.0 693
LLPS-Nec-0828Neurospora crassa63.430.0 694
LLPS-Chr-1190Chlamydomonas reinhardtii63.360.0 704
LLPS-Tru-0299Triticum urartu63.340.0 713
LLPS-Orr-0478Oryza rufipogon63.260.0 679
LLPS-Fus-0529Fusarium solani63.240.0 686
LLPS-Zyt-0650Zymoseptoria tritici63.240.0 689
LLPS-Cog-0906Colletotrichum gloeosporioides63.160.0 677
LLPS-Asfu-0896Aspergillus fumigatus63.020.0 689
LLPS-Gag-0651Gaeumannomyces graminis62.930.0 681
LLPS-Blg-0584Blumeria graminis62.860.0 685
LLPS-Map-0658Magnaporthe poae62.740.0 679
LLPS-Asn-0240Aspergillus nidulans62.710.0 694
LLPS-Fuo-0351Fusarium oxysporum62.670.0 677
LLPS-Fuv-0266Fusarium verticillioides62.670.0 677
LLPS-Nef-0010Neosartorya fischeri62.640.0 689
LLPS-Mao-0271Magnaporthe oryzae62.550.0 682
LLPS-Osl-1149Ostreococcus lucimarinus62.380.0 704
LLPS-Ast-0346Aspergillus terreus62.340.0 687
LLPS-Ved-1206Verticillium dahliae62.240.0 678
LLPS-Aso-0067Aspergillus oryzae62.150.0 687
LLPS-Asf-0211Aspergillus flavus62.150.0 687
LLPS-Asni-1171Aspergillus niger61.920.0 677
LLPS-Asc-0127Aspergillus clavatus61.890.0 682
LLPS-Put-0626Puccinia triticina59.540.0 632
LLPS-Cym-0579Cyanidioschyzon merolae59.110.0 624
LLPS-Chc-0591Chondrus crispus55.30.0 596
LLPS-Ora-0269Ornithorhynchus anatinus36.543e-96 310