• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cap-2497
Cct7

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: T-complex protein 1 subunit eta
Gene Name: Cct7
Ensembl Gene: ENSCPOG00000019869.2
Ensembl Protein: ENSCPOP00000017806.2
Organism: Cavia porcellus
Taxa ID: 10141
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MMPTPVILLK  EGTDSSQGIP  QLVSNISACQ  VIAEAVRTTL  GPRGMDKLIV  DGRGKATISN  60
61    DGATILKLLD  VVHPAAKTLV  DIAKSQDAEV  GDGTTSVTLL  AAEFLKQVKP  YVEEGLHPQI  120
121   IIRAFRTATQ  LAINKIKEIA  VTVKKQDKVE  QRKLLEKCAM  TALSSKLISQ  QKAFFAKMVV  180
181   DAVMMLDDLL  QLKMIGIKKV  QGGALEESQL  VAGVAFKKTF  SYAGFEMQPK  KYNNPMIALL  240
241   NVELELKAEK  DNAEIRVHTV  EDYQAIVDAE  WNILYDKLEK  IYNSGAKVVL  SKLPIGDVAT  300
301   QYFADRDMFC  AGRVPEEDLK  RTMMACGGSI  QTSVNALSAD  VLGRCQLFEE  TQIGGERYNF  360
361   FTGCPKAKTC  TFILRGGAEQ  FMEETERSLH  DAIMIVRRAI  KNDSVVAGGG  AIEMELSKYL  420
421   RDYSRTIPGK  QQLLIGAYAK  ALEIIPRQLC  DNAGFDATNI  LNKLRARHAQ  GGMWYGVDIN  480
481   NEDITDNFEA  FVWEPAMVRI  NALTAASEAA  CLIVSVDETI  KNPRSTVDAP  PAAGRGRGRG  540
541   RLP  543
Nucleotide CDS Sequence (FASTA)
1     ATGATGCCCA  CACCAGTTAT  ACTGTTGAAA  GAGGGAACTG  ACAGTTCCCA  AGGCATCCCT  60
61    CAGCTTGTGA  GTAACATCAG  TGCCTGCCAG  GTGATTGCCG  AGGCTGTAAG  AACCACCCTA  120
121   GGTCCCCGTG  GCATGGACAA  GCTTATTGTG  GATGGCCGAG  GCAAGGCAAC  AATTTCTAAT  180
181   GATGGGGCCA  CAATTTTGAA  ACTTCTTGAT  GTCGTCCATC  CTGCAGCAAA  GACTTTAGTG  240
241   GACATTGCCA  AATCCCAAGA  TGCTGAGGCA  ATTAACAAGA  TCAAAGAGAT  TGCTGTAACT  300
301   GTGAAGAAGC  AAGATAAAGT  GGAGCAGAGG  AAACTGCTGG  AGAAGTGTGC  CATGACAGCT  360
361   CTGAGCTCCA  AGCTGATATC  CCAGCAGAAA  GCCTTCTTTG  CTAAGATGGT  GGTTGATGCT  420
421   GTGATGATGC  TTGATGATTT  GCTGCAGCTT  AAAATGATTG  GAATCAAGAA  GGTACAGGGT  480
481   GGAGCCCTAG  AGGAGTCTCA  GCTGGTGGCC  GGTGTGGCAT  TCAAGAAGAC  TTTCTCTTAC  540
541   GCTGGGTTTG  AAATGCAACC  TAAAAAGTAT  AATAACCCCA  TGATCGCCTT  ATTAAATGTT  600
601   GAACTTGAGC  TGAAAGCTGA  GAAAGACAAT  GCTGAAATCA  GAGTCCATAC  AGTGGAGGAT  660
661   TATCAGGCAA  TTGTTGATGC  TGAGTGGAAC  ATTCTCTATG  ACAAGTTAGA  GAAGATCTAC  720
721   AATTCTGGAG  CCAAAGTTGT  TTTATCCAAA  CTCCCTATTG  GGGATGTAGC  CACCCAGTAC  780
781   TTTGCTGATA  GAGACATGTT  CTGTGCCGGG  CGGGTACCTG  AGGAAGATTT  GAAGAGGACA  840
841   ATGATGGCCT  GTGGAGGTTC  GATCCAGACC  AGTGTGAATG  CTCTATCAGC  AGATGTGCTG  900
901   GGCCGCTGCC  AGCTATTTGA  AGAAACCCAG  ATTGGAGGTG  AAAGGTACAA  TTTCTTCACT  960
961   GGTTGCCCCA  AGGCCAAGAC  TTGCACCTTC  ATCCTCCGTG  GCGGTGCTGA  GCAGTTTATG  1020
1021  GAGGAGACAG  AGCGGTCTCT  GCATGACGCC  ATCATGATCG  TCAGACGGGC  CATCAAGAAT  1080
1081  GATTCAGTGG  TGGCTGGTGG  TGGGGCCATC  GAGATGGAGC  TCTCTAAGTA  CCTGCGGGAT  1140
1141  TACTCAAGGA  CTATCCCAGG  AAAACAGCAG  CTACTGATTG  GAGCATATGC  CAAGGCCTTG  1200
1201  GAGATTATCC  CACGTCAGCT  ATGTGACAAT  GCTGGCTTTG  ATGCCACAAA  CATCTTGAAC  1260
1261  AAACTGCGGG  CTCGGCATGC  CCAGGGGGGC  ATGTGGTATG  GGGTGGACAT  CAACAATGAG  1320
1321  GACATTACTG  ACAACTTTGA  AGCCTTTGTG  TGGGAGCCAG  CTATGGTGCG  GATCAATGCC  1380
1381  CTCACAGCAG  CCTCTGAGGC  TGCATGCCTT  ATCGTGTCTG  TGGATGAGAC  CATCAAGAAC  1440
1441  CCTCGCTCCA  CTGTGGATGC  TCCTCCAGCA  GCTGGCCGGG  GCAGGGGCCG  GGGCCGCCTT  1500
1501  CCTTGA  1506

▼ KEYWORD

ID
Family
ATP-binding
Chaperone
Complete proteome
Cytoplasm
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
ATP binding
Molecular Function
Unfolded protein binding
Biological Process
Protein folding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-1165Fukomys damarensis99.250.01090
LLPS-Fec-1556Felis catus98.310.01083
LLPS-Mup-0899Mustela putorius furo98.310.01082
LLPS-Cas-1265Carlito syrichta98.120.01073
LLPS-Mam-3441Macaca mulatta98.120.01078
LLPS-Rhb-0986Rhinopithecus bieti98.120.01078
LLPS-Man-1535Macaca nemestrina98.120.01077
LLPS-Sus-0956Sus scrofa98.120.01080
LLPS-Maf-2745Macaca fascicularis98.120.01078
LLPS-Chs-0449Chlorocebus sabaeus98.120.01076
LLPS-Gog-2529Gorilla gorilla98.110.01069
LLPS-Hos-0161Homo sapiens97.940.01076
LLPS-Ova-1511Ovis aries97.940.01079
LLPS-Bot-0510Bos taurus97.940.01079
LLPS-Caj-0081Callithrix jacchus97.940.01077
LLPS-Otg-0642Otolemur garnettii97.930.01076
LLPS-Nol-1984Nomascus leucogenys97.920.01068
LLPS-Poa-2456Pongo abelii97.920.01063
LLPS-Mal-0519Mandrillus leucophaeus97.920.01066
LLPS-Caf-1536Canis familiaris97.910.01067
LLPS-Urm-1446Ursus maritimus97.750.01079
LLPS-Eqc-0891Equus caballus97.540.01068
LLPS-Orc-1254Oryctolagus cuniculus97.540.01063
LLPS-Loa-0954Loxodonta africana97.540.01063
LLPS-Aon-0456Aotus nancymaae97.540.01063
LLPS-Cea-0475Cercocebus atys97.50.0 891
LLPS-Aim-0350Ailuropoda melanoleuca97.370.01076
LLPS-Paa-1628Papio anubis97.350.01061
LLPS-Ict-0195Ictidomys tridecemlineatus97.190.01066
LLPS-Pat-0038Pan troglodytes97.190.01068
LLPS-Pap-1498Pan paniscus97.190.01068
LLPS-Dio-1092Dipodomys ordii97.150.01059
LLPS-Ran-1934Rattus norvegicus96.820.01063
LLPS-Mum-0459Mus musculus96.620.01059
LLPS-Mea-0516Mesocricetus auratus96.60.01059
LLPS-Myl-1008Myotis lucifugus96.230.01058
LLPS-Mod-0404Monodelphis domestica96.020.01045
LLPS-Sah-0212Sarcophilus harrisii95.640.01038
LLPS-Gaga-2529Gallus gallus93.950.01028
LLPS-Meg-0725Meleagris gallopavo93.722e-140 412
LLPS-Anp-1323Anas platyrhynchos93.210.01020
LLPS-Fia-0070Ficedula albicollis91.420.0 847
LLPS-Anc-1227Anolis carolinensis90.970.0 920
LLPS-Xet-0421Xenopus tropicalis90.410.01002
LLPS-Asm-0781Astyanax mexicanus90.040.0 984
LLPS-Leo-0283Lepisosteus oculatus89.850.0 997
LLPS-Scf-1583Scleropages formosus89.770.0 991
LLPS-Orl-0835Oryzias latipes89.220.0 987
LLPS-Orn-0180Oreochromis niloticus89.20.0 984
LLPS-Dar-0087Danio rerio89.20.0 989
LLPS-Icp-2112Ictalurus punctatus88.910.0 986
LLPS-Pes-1667Pelodiscus sinensis88.850.0 971
LLPS-Ten-1365Tetraodon nigroviridis88.70.0 985
LLPS-Pof-2329Poecilia formosa88.450.0 980
LLPS-Xim-2361Xiphophorus maculatus88.450.0 982
LLPS-Tar-0639Takifugu rubripes88.210.0 972
LLPS-Scm-0588Scophthalmus maximus87.880.0 970
LLPS-Gaa-2195Gasterosteus aculeatus87.690.0 968
LLPS-Lac-0944Latimeria chalumnae86.280.0 933
LLPS-Cii-1637Ciona intestinalis80.840.0 873
LLPS-Cis-0017Ciona savignyi79.10.0 857
LLPS-Drm-0709Drosophila melanogaster76.530.0 829
LLPS-Abg-0702Absidia glauca70.830.0 766
LLPS-Crn-0886Cryptococcus neoformans68.820.0 758
LLPS-Ors-0659Oryza sativa68.184e-134 399
LLPS-Bro-2432Brassica oleracea67.990.0 734
LLPS-Sem-0094Selaginella moellendorffii67.990.0 716
LLPS-Usm-0014Ustilago maydis67.920.0 746
LLPS-Gor-0050Gossypium raimondii67.80.0 732
LLPS-Art-0817Arabidopsis thaliana67.80.0 733
LLPS-Arl-0485Arabidopsis lyrata67.80.0 734
LLPS-Via-0456Vigna angularis67.80.0 752
LLPS-Brn-0942Brassica napus67.770.0 671
LLPS-Coc-1473Corchorus capsularis67.610.0 723
LLPS-Brr-1670Brassica rapa67.610.0 729
LLPS-Glm-1360Glycine max67.610.0 747
LLPS-Orgl-1297Oryza glumaepatula67.581e-156 460
LLPS-Spr-0152Sporisorium reilianum67.540.0 743
LLPS-Phv-0247Phaseolus vulgaris67.420.0 746
LLPS-Sot-0979Solanum tuberosum67.420.0 732
LLPS-Sol-0162Solanum lycopersicum67.420.0 732
LLPS-Viv-0999Vitis vinifera67.30.0 733
LLPS-Mae-0234Manihot esculenta67.230.0 727
LLPS-Nia-1786Nicotiana attenuata67.230.0 730
LLPS-Thc-0521Theobroma cacao67.230.0 728
LLPS-Dac-0407Daucus carota67.230.0 731
LLPS-Php-0534Physcomitrella patens67.170.0 730
LLPS-Pot-1567Populus trichocarpa67.050.0 750
LLPS-Met-0289Medicago truncatula67.050.0 743
LLPS-Mua-0680Musa acuminata66.920.0 733
LLPS-Prp-0260Prunus persica66.860.0 725
LLPS-Cus-1518Cucumis sativus66.860.0 730
LLPS-Vir-1446Vigna radiata66.730.0 743
LLPS-Hea-2470Helianthus annuus66.670.0 726
LLPS-Tum-0533Tuber melanosporum66.540.0 736
LLPS-Amt-0862Amborella trichopoda66.480.0 725
LLPS-Hov-0251Hordeum vulgare66.410.0 715
LLPS-Zem-0364Zea mays66.350.0 727
LLPS-Brd-0145Brachypodium distachyon66.350.0 722
LLPS-Tra-1559Triticum aestivum66.350.0 716
LLPS-Miv-0637Microbotryum violaceum66.220.0 743
LLPS-Sob-0399Sorghum bicolor66.160.0 724
LLPS-Sei-0952Setaria italica66.160.0 721
LLPS-Orbr-1216Oryza brachyantha65.970.0 722
LLPS-Kop-0150Komagataella pastoris65.90.0 710
LLPS-Org-0250Oryza glaberrima65.780.0 722
LLPS-Orp-0708Oryza punctata65.780.0 718
LLPS-Lep-0839Leersia perrieri65.780.0 720
LLPS-Orni-0180Oryza nivara65.780.0 722
LLPS-Orb-1303Oryza barthii65.780.0 722
LLPS-Chc-0591Chondrus crispus65.744e-113 352
LLPS-Scp-0202Schizosaccharomyces pombe65.730.0 719
LLPS-Pyt-0096Pyrenophora teres65.51e-177 514
LLPS-Gas-0082Galdieria sulphuraria65.270.0 736
LLPS-Ori-0589Oryza indica65.210.0 705
LLPS-Cae-0128Caenorhabditis elegans64.950.0 729
LLPS-Mel-0617Melampsora laricipopulina64.770.0 716
LLPS-Scj-0383Schizosaccharomyces japonicus64.720.0 709
LLPS-Scc-0195Schizosaccharomyces cryophilus64.560.0 705
LLPS-Asg-0536Ashbya gossypii64.50.0 704
LLPS-Pug-1212Puccinia graminis64.120.0 711
LLPS-Sac-0914Saccharomyces cerevisiae64.120.0 699
LLPS-Yal-0963Yarrowia lipolytica64.040.0 712
LLPS-Tru-0299Triticum urartu63.570.0 704
LLPS-Chr-1190Chlamydomonas reinhardtii63.50.0 708
LLPS-Dos-0002Dothistroma septosporum63.450.0 700
LLPS-Beb-0657Beauveria bassiana63.410.0 689
LLPS-Trv-0614Trichoderma virens63.010.0 697
LLPS-Trr-0426Trichoderma reesei63.010.0 695
LLPS-Zyt-0650Zymoseptoria tritici62.970.0 696
LLPS-Blg-0584Blumeria graminis62.780.0 694
LLPS-Cog-0906Colletotrichum gloeosporioides62.770.0 677
LLPS-Orr-0478Oryza rufipogon62.740.0 666
LLPS-Pytr-0739Pyrenophora triticirepentis62.520.0 689
LLPS-Cogr-0742Colletotrichum graminicola62.410.0 694
LLPS-Nec-0828Neurospora crassa62.220.0 691
LLPS-Osl-1149Ostreococcus lucimarinus62.070.0 686
LLPS-Phn-0686Phaeosphaeria nodorum61.950.0 654
LLPS-Fus-0529Fusarium solani61.90.0 683
LLPS-Lem-0969Leptosphaeria maculans61.770.0 686
LLPS-Asfu-0896Aspergillus fumigatus61.730.0 678
LLPS-Mao-0271Magnaporthe oryzae61.730.0 681
LLPS-Coo-0535Colletotrichum orbiculare61.710.0 690
LLPS-Fuo-0351Fusarium oxysporum61.520.0 680
LLPS-Fuv-0266Fusarium verticillioides61.520.0 680
LLPS-Ved-1206Verticillium dahliae61.420.0 677
LLPS-Asn-0240Aspergillus nidulans61.420.0 686
LLPS-Nef-0010Neosartorya fischeri61.350.0 677
LLPS-Ast-0346Aspergillus terreus61.180.0 683
LLPS-Gag-0651Gaeumannomyces graminis61.160.0 676
LLPS-Asf-0211Aspergillus flavus61.050.0 682
LLPS-Aso-0067Aspergillus oryzae61.050.0 682
LLPS-Asc-0127Aspergillus clavatus60.60.0 672
LLPS-Map-0658Magnaporthe poae60.410.0 672
LLPS-Asni-1171Aspergillus niger60.30.0 671
LLPS-Put-0626Puccinia triticina59.350.0 629
LLPS-Cym-0579Cyanidioschyzon merolae59.110.0 625