• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Anp-1323
CCT7

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: T-complex protein 1 subunit eta
Gene Name: CCT7
Ensembl Gene: ENSAPLG00000014343.1
Ensembl Protein: ENSAPLP00000014219.1
Organism: Anas platyrhynchos
Taxa ID: 8839
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAPLT00000014994.1ENSAPLP00000014219.1
UniProtU3J3Z2, U3J3Z2_ANAPL
GeneBankADON01101227, ADON01101226

▼ SEQUENCE

Protein Sequence (FASTA)
1     PQPTPVILLK  EGTDTSQGIP  QLVSNINACQ  VIAEAVRTTL  GPRGMDKLIV  DDRGKATISN  60
61    DGATILKLLD  VVHPAAKTLV  DIAKSQDAEV  GDGTTSVTLL  AAEFLKQVKP  YVEEGLHPQI  120
121   IIRAFRTATQ  LAVNKIKDIA  VSVKKEDKDE  QRSLLEKCAA  TALSSKLISQ  SKDFFSKMVV  180
181   DAVMMLDDLL  QLKMIGIKKV  QGGALEDSQL  VAGVAFKKTF  SYAGFEMQPK  KYQAPKIALL  240
241   NVELELKAEK  DNAEVRVNTV  QDYQAIVDAE  WNILYDKLDK  IHKSGAKVVL  SKLPIGDVAT  300
301   QYFADRDMFC  AGRVPEEDLK  RTMMACGGSI  QTSVNALADD  VLGRCELFEE  TQIGGDRYNL  360
361   FTGCPKAKTC  TIILRGGAEQ  FMEETERSLH  DAIMIVRRAI  KNDSVVAGGG  AIEMELSKYL  420
421   RDYSRTIPGK  QQLLIGAYAK  ALEIIPRQLC  DNAGFDATNI  LNKLRAKHAQ  GGMWYGVDVN  480
481   NEDIANNFEA  CVWEPAIVRI  NALTAASEAA  CLIVSVDETI  KNPRSTVDAP  GATGQGGKRG  540
541   RLV  543
Nucleotide CDS Sequence (FASTA)
1     CCCCAGCCAA  CACCAGTTAT  CCTGCTGAAG  GAGGGCACCG  ACACCTCGCA  GGGGATCCCG  60
61    CAGCTCGTCA  GCAACATCAA  TGCCTGCCAG  GTGATCGCCG  AGGCCGTGCG  TACCACGCTG  120
121   GGGCCGCGGG  GCATGGACAA  ACTCATCGTG  GATGACCGGG  GCAAAGCCAC  CATCTCTAAC  180
181   GATGGCGCCA  CCATCCTAAA  GCTCCTGGAC  GTTGTCCACC  CGGCCGCGAA  GACGTTGGTG  240
241   GACATCGCCA  AGTCTCAGGA  TGCCGAGGTT  GGCGATGGCA  CCACGTCCGT  CACGCTGCTC  300
301   GCTGCCGAGT  TCCTGAAGCA  GGTGAAGCCC  TACGTGGAGG  AAGGCCTCCA  CCCTCAGATC  360
361   ATCATCCGTG  CCTTCCGCAC  CGCCACACAG  CTGGCTGTGA  ACAAGATCAA  AGACATCGCT  420
421   GTTTCCGTCA  AGAAGGAAGA  TAAAGACGAG  CAGAGAAGCC  TGCTGGAGAA  GTGTGCAGCC  480
481   ACAGCCCTGA  GCTCCAAGCT  GATCTCCCAG  AGCAAGGACT  TTTTTTCCAA  GATGGTGGTG  540
541   GATGCTGTCA  TGATGCTGGA  CGACTTGCTG  CAGCTCAAAA  TGATCGGGAT  AAAGAAGGTG  600
601   CAAGGAGGGG  CTCTGGAAGA  CTCGCAGCTG  GTGGCCGGAG  TTGCCTTTAA  GAAGACGTTT  660
661   TCCTACGCCG  GCTTTGAGAT  GCAGCCCAAG  AAGTACCAGG  CTCCCAAAAT  CGCCCTGCTG  720
721   AACGTGGAGC  TGGAGCTCAA  AGCGGAGAAA  GACAACGCCG  AAGTCAGAGT  GAACACTGTG  780
781   CAGGACTACC  AGGCCATCGT  GGACGCCGAA  TGGAACATTT  TGTACGACAA  GCTAGACAAA  840
841   ATTCACAAGT  CGGGAGCCAA  AGTCGTCCTG  TCCAAGCTTC  CCATCGGCGA  TGTGGCTACT  900
901   CAGTACTTCG  CGGACAGAGA  CATGTTCTGT  GCTGGCCGTG  TCCCGGAGGA  AGATCTCAAG  960
961   AGAACCATGA  TGGCCTGCGG  CGGATCCATT  CAGACCAGCG  TGAACGCCCT  GGCAGACGAC  1020
1021  GTGCTGGGCC  GATGCGAGCT  CTTTGAGGAG  ACTCAGATCG  GAGGAGATAG  GTATAACCTC  1080
1081  TTCACGGGCT  GCCCGAAAGC  CAAGACGTGC  ACGATAATCC  TGCGAGGAGG  CGCCGAGCAG  1140
1141  TTCATGGAGG  AGACGGAACG  GTCCCTGCAC  GATGCCATCA  TGATAGTGCG  GAGAGCCATC  1200
1201  AAGAATGACT  CGGTGGTTGC  CGGCGGTGGC  GCGATAGAGA  TGGAGCTCTC  CAAATACCTC  1260
1261  CGCGACTACT  CCAGGACCAT  TCCGGGCAAG  CAGCAGCTGC  TGATAGGAGC  TTACGCTAAA  1320
1321  GCCCTTGAGA  TCATTCCCCG  GCAACTCTGT  GACAACGCCG  GCTTCGATGC  CACCAACATC  1380
1381  CTGAACAAGC  TGCGAGCCAA  GCACGCACAG  GGCGGCATGT  GGTACGGCGT  GGACGTCAAC  1440
1441  AACGAGGACA  TCGCCAACAA  CTTCGAGGCC  TGCGTGTGGG  AGCCGGCCAT  CGTGCGCATC  1500
1501  AACGCGCTGA  CGGCCGCCTC  CGAGGCCGCC  TGCCTCATCG  TGTCCGTCGA  CGAGACCATC  1560
1561  AAAAATCCCC  GCTCCACCGT  GGACGCCCCG  GGGGCGACGG  GGCAGGGGGG  GAAAAGGGGA  1620
1621  CGTTTGGTT  1629

▼ KEYWORD

ID
Family
ATP-binding
Chaperone
Complete proteome
Cytoplasm
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cell body
Cellular Component
Chaperonin-containing T-complex
Cellular Component
Microtubule
Molecular Function
ATP binding
Molecular Function
Identical protein binding
Molecular Function
Unfolded protein binding
Biological Process
Binding of sperm to zona pellucida
Biological Process
Positive regulation of establishment of protein localization to telomere
Biological Process
Positive regulation of telomere maintenance via telomerase
Biological Process
Protein folding
Biological Process
Protein stabilization
Biological Process
Toxin transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gaga-2529Gallus gallus98.670.01069
LLPS-Meg-0725Meleagris gallopavo96.623e-144 422
LLPS-Fia-0070Ficedula albicollis96.370.0 883
LLPS-Loa-0954Loxodonta africana94.110.01020
LLPS-Mam-3441Macaca mulatta93.920.01019
LLPS-Cas-1265Carlito syrichta93.920.01015
LLPS-Man-1535Macaca nemestrina93.920.01019
LLPS-Rhb-0986Rhinopithecus bieti93.920.01019
LLPS-Mup-0899Mustela putorius furo93.920.01022
LLPS-Maf-2745Macaca fascicularis93.920.01019
LLPS-Chs-0449Chlorocebus sabaeus93.920.01019
LLPS-Gog-2529Gorilla gorilla93.920.01019
LLPS-Hos-0161Homo sapiens93.770.01025
LLPS-Caf-1536Canis familiaris93.730.01019
LLPS-Poa-2456Pongo abelii93.730.01014
LLPS-Nol-1984Nomascus leucogenys93.730.01019
LLPS-Fec-1556Felis catus93.730.01021
LLPS-Mal-0519Mandrillus leucophaeus93.730.01017
LLPS-Aon-0456Aotus nancymaae93.730.01016
LLPS-Bot-0510Bos taurus93.580.01024
LLPS-Ova-1511Ovis aries93.580.01024
LLPS-Sus-0956Sus scrofa93.540.01017
LLPS-Urm-1446Ursus maritimus93.40.01023
LLPS-Myl-1008Myotis lucifugus93.40.01022
LLPS-Paa-1628Papio anubis93.330.01013
LLPS-Cap-2497Cavia porcellus93.210.01020
LLPS-Aim-0350Ailuropoda melanoleuca93.210.01023
LLPS-Pap-1498Pan paniscus93.190.01018
LLPS-Pat-0038Pan troglodytes93.190.01018
LLPS-Mea-0516Mesocricetus auratus93.180.01018
LLPS-Cea-0475Cercocebus atys93.180.0 852
LLPS-Eqc-0891Equus caballus93.160.01014
LLPS-Mod-0404Monodelphis domestica93.160.01007
LLPS-Fud-1165Fukomys damarensis93.020.01020
LLPS-Otg-0642Otolemur garnettii92.830.01015
LLPS-Caj-0081Callithrix jacchus92.760.01028
LLPS-Sah-0212Sarcophilus harrisii92.610.01002
LLPS-Ict-0195Ictidomys tridecemlineatus92.550.01022
LLPS-Orc-1254Oryctolagus cuniculus92.020.01000
LLPS-Ran-1934Rattus norvegicus91.870.01025
LLPS-Dio-1092Dipodomys ordii91.60.01011
LLPS-Xet-0421Xenopus tropicalis91.590.01018
LLPS-Anc-1227Anolis carolinensis91.350.0 939
LLPS-Mum-0459Mus musculus91.130.01019
LLPS-Dar-0087Danio rerio91.050.01000
LLPS-Asm-0781Astyanax mexicanus90.960.0 987
LLPS-Pes-1667Pelodiscus sinensis90.750.0 991
LLPS-Leo-0283Lepisosteus oculatus90.510.0 995
LLPS-Scf-1583Scleropages formosus90.110.0 990
LLPS-Orn-0180Oreochromis niloticus89.920.0 988
LLPS-Icp-2112Ictalurus punctatus89.620.0 991
LLPS-Ten-1365Tetraodon nigroviridis89.450.0 990
LLPS-Orl-0835Oryzias latipes89.370.0 978
LLPS-Gaa-2195Gasterosteus aculeatus89.350.0 981
LLPS-Xim-2361Xiphophorus maculatus89.160.0 980
LLPS-Tar-0639Takifugu rubripes88.990.0 984
LLPS-Pof-2329Poecilia formosa88.970.0 980
LLPS-Scm-0588Scophthalmus maximus88.610.0 974
LLPS-Lac-0944Latimeria chalumnae86.820.0 943
LLPS-Cii-1637Ciona intestinalis80.380.0 875
LLPS-Cis-0017Ciona savignyi78.560.0 862
LLPS-Drm-0709Drosophila melanogaster77.10.0 839
LLPS-Abg-1654Absidia glauca70.530.0 757
LLPS-Ors-0659Oryza sativa69.324e-136 404
LLPS-Gor-0050Gossypium raimondii69.070.0 745
LLPS-Glm-1360Glycine max69.070.0 761
LLPS-Php-0534Physcomitrella patens69.070.0 744
LLPS-Crn-0886Cryptococcus neoformans68.950.0 752
LLPS-Coc-1473Corchorus capsularis68.880.0 736
LLPS-Sem-0094Selaginella moellendorffii68.880.0 720
LLPS-Orgl-1297Oryza glumaepatula68.818e-161 470
LLPS-Bro-2432Brassica oleracea68.690.0 739
LLPS-Art-0817Arabidopsis thaliana68.690.0 743
LLPS-Via-0456Vigna angularis68.690.0 758
LLPS-Sol-0162Solanum lycopersicum68.690.0 744
LLPS-Brr-1670Brassica rapa68.50.0 737
LLPS-Phv-0247Phaseolus vulgaris68.50.0 755
LLPS-Nia-1786Nicotiana attenuata68.50.0 742
LLPS-Sot-0979Solanum tuberosum68.50.0 743
LLPS-Met-0289Medicago truncatula68.50.0 757
LLPS-Arl-0485Arabidopsis lyrata68.50.0 742
LLPS-Thc-0521Theobroma cacao68.50.0 741
LLPS-Dac-0407Daucus carota68.50.0 743
LLPS-Mua-0680Musa acuminata68.190.0 744
LLPS-Viv-0999Vitis vinifera68.180.0 742
LLPS-Prp-0260Prunus persica68.120.0 739
LLPS-Pot-1567Populus trichocarpa68.120.0 761
LLPS-Vir-1446Vigna radiata67.980.0 753
LLPS-Brn-0942Brassica napus67.980.0 677
LLPS-Hea-2362Helianthus annuus67.930.0 734
LLPS-Brd-0145Brachypodium distachyon67.810.0 734
LLPS-Org-0250Oryza glaberrima67.430.0 738
LLPS-Orp-0708Oryza punctata67.430.0 737
LLPS-Sei-0952Setaria italica67.430.0 734
LLPS-Orb-1303Oryza barthii67.430.0 738
LLPS-Orni-0180Oryza nivara67.430.0 738
LLPS-Usm-0014Ustilago maydis67.340.0 747
LLPS-Cus-1518Cucumis sativus67.340.0 748
LLPS-Sob-0399Sorghum bicolor67.240.0 736
LLPS-Lep-0839Leersia perrieri67.240.0 736
LLPS-Miv-0637Microbotryum violaceum67.170.0 746
LLPS-Zem-0364Zea mays67.050.0 733
LLPS-Orbr-1216Oryza brachyantha67.050.0 734
LLPS-Tra-1559Triticum aestivum67.050.0 723
LLPS-Spr-0152Sporisorium reilianum66.970.0 744
LLPS-Hov-0251Hordeum vulgare66.920.0 732
LLPS-Mae-0234Manihot esculenta66.910.0 740
LLPS-Ori-0589Oryza indica66.860.0 721
LLPS-Tum-0533Tuber melanosporum66.670.0 731
LLPS-Pyt-0096Pyrenophora teres66.585e-178 514
LLPS-Amt-0862Amborella trichopoda66.110.0 736
LLPS-Gas-0082Galdieria sulphuraria65.960.0 734
LLPS-Scp-0202Schizosaccharomyces pombe65.870.0 731
LLPS-Kop-0150Komagataella pastoris65.830.0 704
LLPS-Scc-0195Schizosaccharomyces cryophilus64.750.0 713
LLPS-Cae-0128Caenorhabditis elegans64.540.0 729
LLPS-Orr-0478Oryza rufipogon64.380.0 683
LLPS-Mel-0617Melampsora laricipopulina64.370.0 717
LLPS-Tru-0299Triticum urartu64.230.0 711
LLPS-Pug-1212Puccinia graminis64.230.0 716
LLPS-Yal-0963Yarrowia lipolytica64.230.0 711
LLPS-Chr-1190Chlamydomonas reinhardtii64.070.0 705
LLPS-Trr-0426Trichoderma reesei63.990.0 702
LLPS-Asg-0536Ashbya gossypii63.770.0 708
LLPS-Scj-0383Schizosaccharomyces japonicus63.720.0 706
LLPS-Trv-0614Trichoderma virens63.430.0 697
LLPS-Pytr-0739Pyrenophora triticirepentis63.310.0 694
LLPS-Osl-1149Ostreococcus lucimarinus63.120.0 692
LLPS-Blg-0584Blumeria graminis63.040.0 690
LLPS-Lem-0969Leptosphaeria maculans62.930.0 694
LLPS-Beb-0657Beauveria bassiana62.830.0 688
LLPS-Zyt-0650Zymoseptoria tritici62.80.0 693
LLPS-Sac-0914Saccharomyces cerevisiae62.730.0 699
LLPS-Coo-0535Colletotrichum orbiculare62.690.0 697
LLPS-Cog-0906Colletotrichum gloeosporioides62.650.0 675
LLPS-Phn-0686Phaeosphaeria nodorum62.620.0 654
LLPS-Dos-0002Dothistroma septosporum62.590.0 699
LLPS-Cogr-0742Colletotrichum graminicola62.310.0 694
LLPS-Nec-0828Neurospora crassa62.310.0 691
LLPS-Fus-0529Fusarium solani61.940.0 681
LLPS-Ast-0346Aspergillus terreus61.930.0 683
LLPS-Fuo-0351Fusarium oxysporum61.750.0 678
LLPS-Fuv-0266Fusarium verticillioides61.750.0 679
LLPS-Gag-0651Gaeumannomyces graminis61.710.0 683
LLPS-Ved-1206Verticillium dahliae61.670.0 681
LLPS-Mao-0271Magnaporthe oryzae61.640.0 681
LLPS-Asn-0240Aspergillus nidulans61.60.0 687
LLPS-Asc-0127Aspergillus clavatus61.290.0 674
LLPS-Map-0658Magnaporthe poae61.270.0 678
LLPS-Aso-0067Aspergillus oryzae61.040.0 682
LLPS-Asf-0211Aspergillus flavus61.040.0 682
LLPS-Asni-1171Aspergillus niger60.960.0 667
LLPS-Asfu-0896Aspergillus fumigatus60.780.0 672
LLPS-Nef-0010Neosartorya fischeri60.780.0 676
LLPS-Put-0626Puccinia triticina59.510.0 637
LLPS-Cym-0579Cyanidioschyzon merolae59.110.0 628
LLPS-Chc-0591Chondrus crispus55.660.0 595
LLPS-Orm-0219Oryza meridionalis38.126e-99 317