• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Nol-2848
MAPK8

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Mitogen-activated protein kinase
Gene Name: MAPK8
Ensembl Gene: ENSNLEG00000033138.1
Ensembl Protein: ENSNLEP00000039564.1
Organism: Nomascus leucogenys
Taxa ID: 61853
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, Neuronal granule, P-body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSRSKRDNNF  YSVEIGDSTF  TVLKRYQNLK  PIGSGAQGIV  CAAYDAILER  NVAIKKLSRP  60
61    FQNQTHAKRA  YRELVLMKCV  NHKNIIGLLN  VFTPQKSLEE  FQDVYIVMEL  MDANLCQVIQ  120
121   MELDHERMSY  LLYQMLCGIK  HLHSAGIIHR  DLKPSNIVVK  SDCTLKILDF  GLARTAGTSF  180
181   MMTPYVVTRY  YRAPEVILGM  GYKENVDIWS  VGCIMGEMIK  GGVLFPGTDH  IDQWNKVIEQ  240
241   LGTPCPEFMK  KLQPTVRTYV  ENRPKYAGYS  FEKLFPDVLF  PADSEHNKLK  ASQARDLLSK  300
301   MLVIDASKRI  SVDEALQHPY  INVWYDPSEA  EAPPPKIPDK  QLDEREHTIE  EWKELIYKEV  360
361   MDLEERTKNG  VIRGQPSPLG  AAVINGSQHP  SSSSSVNDVS  SMSTDPTLAS  DTDSSLEASA  420
421   GPLGCCR  427
Nucleotide CDS Sequence (FASTA)
1     ATGAGCAGAA  GCAAGCGTGA  CAACAATTTT  TATAGTGTAG  AGATTGGAGA  TTCTACATTC  60
61    ACAGTCCTGA  AACGATATCA  GAATTTAAAA  CCTATAGGCT  CAGGAGCTCA  AGGAATAGTA  120
121   TGCGCAGCTT  ATGATGCCAT  TCTTGAAAGA  AATGTTGCAA  TCAAGAAGCT  AAGCCGACCA  180
181   TTTCAGAATC  AGACTCATGC  CAAGCGGGCC  TACAGAGAGC  TAGTTCTTAT  GAAATGTGTT  240
241   AATCACAAAA  ATATAATTGG  CCTTTTGAAT  GTTTTCACAC  CACAGAAATC  CCTAGAAGAA  300
301   TTTCAAGATG  TTTACATAGT  CATGGAGCTC  ATGGATGCAA  ATCTTTGCCA  AGTGATTCAG  360
361   ATGGAGCTAG  ATCATGAAAG  AATGTCCTAC  CTTCTCTATC  AGATGCTGTG  TGGAATCAAG  420
421   CACCTTCATT  CTGCTGGAAT  TATTCATCGG  GACTTAAAGC  CCAGTAATAT  AGTAGTAAAA  480
481   TCTGACTGCA  CTTTGAAGAT  TCTTGACTTC  GGTCTGGCCA  GGACTGCAGG  AACGAGTTTT  540
541   ATGATGACGC  CTTACGTAGT  GACTCGCTAC  TACAGAGCAC  CCGAGGTCAT  CCTCGGCATG  600
601   GGCTACAAGG  AAAACGCTGA  CTCGGAACAC  AACAAACTTA  AAGCCAGTCA  GGCAAGGGAT  660
661   TTGTTATCCA  AAATGCTGGT  AATAGATGCA  TCTAAAAGGA  TCTCTGTAGA  TGAAGCTCTC  720
721   CAACACCCGT  ACATCAATGT  CTGGTATGAT  CCTTCTGAAG  CAGAAGCTCC  ACCACCAAAG  780
781   ATCCCTGACA  AGCAGTTAGA  TGAAAGAGAA  CACACAATAG  AAGAGTGGAA  AGAACTGATA  840
841   TATAAGGAAG  TTATGGACTT  GGAGGAGAGA  ACCAAGAATG  GAGTTATACG  GGGGCAGCCC  900
901   TCTCCTTTAG  GTTGGTTACA  ATATAAGCTT  GGTTAA  936

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gog-1946Gorilla gorilla100.00.0 852
LLPS-Aon-1530Aotus nancymaae100.00.0 795
LLPS-Maf-1240Macaca fascicularis100.00.0 852
LLPS-Man-2362Macaca nemestrina100.00.0 852
LLPS-Pat-1543Pan troglodytes100.00.0 852
LLPS-Pap-2454Pan paniscus100.00.0 852
LLPS-Fud-2168Fukomys damarensis99.770.0 847
LLPS-Fec-1857Felis catus99.770.0 850
LLPS-Eqc-1347Equus caballus99.770.0 850
LLPS-Dio-2076Dipodomys ordii99.530.0 847
LLPS-Meg-1938Meleagris gallopavo99.530.0 849
LLPS-Mum-4526Mus musculus99.30.0 853
LLPS-Orc-2570Oryctolagus cuniculus99.30.0 842
LLPS-Mod-2184Monodelphis domestica99.210.0 793
LLPS-Ova-3892Ovis aries98.590.0 843
LLPS-Paa-0139Papio anubis98.130.0 836
LLPS-Mal-0743Mandrillus leucophaeus98.130.0 836
LLPS-Otg-1816Otolemur garnettii98.130.0 836
LLPS-Caj-3307Callithrix jacchus97.890.0 836
LLPS-Mea-1725Mesocricetus auratus97.890.0 838
LLPS-Aim-3341Ailuropoda melanoleuca97.890.0 834
LLPS-Hos-1461Homo sapiens97.890.0 835
LLPS-Ict-2905Ictidomys tridecemlineatus97.890.0 834
LLPS-Cap-2762Cavia porcellus97.890.0 778
LLPS-Sus-3897Sus scrofa97.660.0 833
LLPS-Myl-3011Myotis lucifugus97.660.0 837
LLPS-Mam-1700Macaca mulatta97.660.0 827
LLPS-Poa-0587Pongo abelii97.630.0 779
LLPS-Anp-0236Anas platyrhynchos97.440.0 830
LLPS-Tag-0246Taeniopygia guttata97.420.0 832
LLPS-Gaga-1674Gallus gallus97.420.0 832
LLPS-Pes-0269Pelodiscus sinensis96.970.0 825
LLPS-Loa-0067Loxodonta africana96.960.0 829
LLPS-Sah-2646Sarcophilus harrisii96.740.0 821
LLPS-Mup-3584Mustela putorius furo96.110.0 776
LLPS-Anc-1487Anolis carolinensis95.550.0 827
LLPS-Ran-0046Rattus norvegicus95.080.0 812
LLPS-Lac-1682Latimeria chalumnae93.440.0 807
LLPS-Ora-3489Ornithorhynchus anatinus91.620.0 744
LLPS-Bot-3844Bos taurus91.10.0 792
LLPS-Urm-0196Ursus maritimus90.870.0 791
LLPS-Fia-2071Ficedula albicollis90.40.0 785
LLPS-Tar-0961Takifugu rubripes90.290.0 733
LLPS-Xim-0084Xiphophorus maculatus90.290.0 734
LLPS-Cea-3887Cercocebus atys89.930.0 781
LLPS-Chs-3688Chlorocebus sabaeus89.930.0 782
LLPS-Rhb-2527Rhinopithecus bieti89.930.0 783
LLPS-Cas-3988Carlito syrichta89.930.0 781
LLPS-Caf-4240Canis familiaris89.930.0 782
LLPS-Leo-3460Lepisosteus oculatus88.810.0 771
LLPS-Dar-3841Danio rerio87.590.0 769
LLPS-Scf-3946Scleropages formosus87.390.0 769
LLPS-Asm-2019Astyanax mexicanus86.650.0 764
LLPS-Cis-1640Ciona savignyi80.839e-109 335
LLPS-Cae-1703Caenorhabditis elegans51.281e-119 361
LLPS-Orn-0239Oreochromis niloticus50.73e-118 356
LLPS-Pof-1810Poecilia formosa50.74e-110 335
LLPS-Ten-0041Tetraodon nigroviridis50.286e-118 356
LLPS-Scm-3750Scophthalmus maximus50.143e-117 354
LLPS-Icp-3182Ictalurus punctatus50.05e-112 340
LLPS-Orl-1411Oryzias latipes50.03e-112 341
LLPS-Gaa-2747Gasterosteus aculeatus49.187e-111 338
LLPS-Xet-2512Xenopus tropicalis48.482e-110 336
LLPS-Drm-0463Drosophila melanogaster46.562e-107 328
LLPS-Tut-1878Tursiops truncatus46.171e-107 329