LLPS-Fec-1857
MAPK8
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitogen-activated protein kinase |
| Gene Name: | MAPK8 |
| Ensembl Gene: | ENSFCAG00000003342.5 |
| Ensembl Protein: | ENSFCAP00000029265.1 |
| Organism: | Felis catus |
| Taxa ID: | 9685 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Neuronal granule, P-body, Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSFCAT00000033707.2 | ENSFCAP00000029265.1 |
| Ensembl | ENSFCAT00000056577.1 | ENSFCAP00000043495.1 |
| Ensembl | ENSFCAT00000041895.2 | ENSFCAP00000038654.1 |
| Ensembl | ENSFCAT00000003342.5 | ENSFCAP00000003081.5 |
| Ensembl | ENSFCAT00000054734.1 | ENSFCAP00000045859.1 |
| UniProt | A0A2I2V255, A0A2I2V255_FELCA | |
| GeneBank | AANG04000273 | |
| RefSeq | XM_003994155.4, XM_006937958.3 | XP_003994204.1, XP_006938020.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSRSKRDSNF YSVEIGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAILER NVAIKKLSRP 60 61 FQNQTHAKRA YRELVLMKCV NHKNIIGLLN VFTPQKSLEE FQDVYIVMEL MDANLCQVIQ 120 121 MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTAGTSF 180 181 MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGEMIK GGVLFPGTDH IDQWNKVIEQ 240 241 LGTPCPEFMK KLQPTVRTYV ENRPKYAGYS FEKLFPDVLF PADSEHNKLK ASQARDLLSK 300 301 MLVIDASKRI SVDEALQHPY INVWYDPSEA EAPPPKIPDK QLDEREHTIE EWKELIYKEV 360 361 MDLEERTKNG VIRGQPSPLG AAVINGSQHP SSSSSVNDVS SMSTDPTLAS DTDSSLEASA 420 421 GPLGCCR 427 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGCAGAA GCAAGCGTGA CAGCAATTTT TATAGTGTAG AGATTGGAGA TTCTACATTT 60 61 ACAGTTTTGA AACGATATCA GAATTTAAAA CCTATAGGCT CAGGAGCTCA AGGAATAGTA 120 121 TGTGCAGCTT ATGATGCCAT TCTGGAAAGA AATGTTGCAA TCAAGAAGCT GAGCCGGCCG 180 181 TTTCAGAATC AGACTCATGC TAAACGGGCT TACAGAGAGC TAGTTCTAAT GAAATGTGTT 240 241 AATCACAAAA ATATAATTGG CCTTTTGAAT GTTTTCACAC CACAGAAATC CCTAGAAGAA 300 301 TTTCAAGATG TTTACATAGT CATGGAGCTC ATGGATGCAA ATCTTTGCCA AGTGATTCAG 360 361 ATGGAACTAG ATCATGAAAG AATGTCCTAC CTTCTCTATC AGATGCTGTG TGGAATCAAG 420 421 CACCTTCACT CTGCTGGAAT TATTCATCGG GACTTAAAGC CCAGTAATAT AGTGGTAAAA 480 481 TCAGACTGCA CTTTGAAGAT TCTTGACTTT GGACTGGCCA GGACTGCAGG AACTAGTTTT 540 541 ATGATGACGC CTTACGTAGT GACTCGCTAC TACAGAGCAC CTGAGGTCAT CCTAGGGATG 600 601 GGCTACAAAG AAAACGCTGA CTCGGAACAC AACAAACTTA AAGCCAGTCA GGCAAGGGAC 660 661 TTGTTATCCA AAATGCTGGT AATTGATGCA TCTAAAAGGA TCTCTGTAGA TGAAGCCCTC 720 721 CAGCATCCAT ATATCAATGT CTGGTATGAT CCTTCTGAAG CAGAAGCTCC ACCACCCAAG 780 781 ATACCTGACA AGCAATTAGA TGAAAGGGAA CATACAATAG AAGAGTGGAA AGAGTTGATA 840 841 TACAAAGAAG TTATGGACTT GGAGGAGAGA ACCAAGAATG GAGTTATACG GGGGCAGCCC 900 901 TCTCCTTTAG CACAGGTGCA GCAGTGA 927 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Eqc-1347 | Equus caballus | 100.0 | 0.0 | 851 |
| LLPS-Nol-2848 | Nomascus leucogenys | 99.77 | 0.0 | 850 |
| LLPS-Pat-1543 | Pan troglodytes | 99.77 | 0.0 | 850 |
| LLPS-Pap-2454 | Pan paniscus | 99.77 | 0.0 | 850 |
| LLPS-Man-2362 | Macaca nemestrina | 99.77 | 0.0 | 850 |
| LLPS-Maf-1240 | Macaca fascicularis | 99.77 | 0.0 | 850 |
| LLPS-Gog-1946 | Gorilla gorilla | 99.77 | 0.0 | 850 |
| LLPS-Aon-1530 | Aotus nancymaae | 99.74 | 0.0 | 793 |
| LLPS-Fud-2168 | Fukomys damarensis | 99.53 | 0.0 | 845 |
| LLPS-Mod-2184 | Monodelphis domestica | 99.47 | 0.0 | 794 |
| LLPS-Meg-1938 | Meleagris gallopavo | 99.3 | 0.0 | 847 |
| LLPS-Dio-2076 | Dipodomys ordii | 99.3 | 0.0 | 845 |
| LLPS-Orc-2570 | Oryctolagus cuniculus | 99.06 | 0.0 | 841 |
| LLPS-Mum-4526 | Mus musculus | 99.06 | 0.0 | 852 |
| LLPS-Ova-3892 | Ovis aries | 98.83 | 0.0 | 844 |
| LLPS-Aim-3341 | Ailuropoda melanoleuca | 98.13 | 0.0 | 835 |
| LLPS-Otg-1816 | Otolemur garnettii | 97.89 | 0.0 | 834 |
| LLPS-Paa-0139 | Papio anubis | 97.89 | 0.0 | 834 |
| LLPS-Mal-0743 | Mandrillus leucophaeus | 97.89 | 0.0 | 834 |
| LLPS-Myl-3011 | Myotis lucifugus | 97.89 | 0.0 | 838 |
| LLPS-Sus-3897 | Sus scrofa | 97.89 | 0.0 | 834 |
| LLPS-Ict-2905 | Ictidomys tridecemlineatus | 97.66 | 0.0 | 832 |
| LLPS-Hos-1461 | Homo sapiens | 97.66 | 0.0 | 833 |
| LLPS-Mea-1725 | Mesocricetus auratus | 97.66 | 0.0 | 837 |
| LLPS-Caj-3307 | Callithrix jacchus | 97.66 | 0.0 | 834 |
| LLPS-Cap-2762 | Cavia porcellus | 97.63 | 0.0 | 775 |
| LLPS-Mam-1700 | Macaca mulatta | 97.42 | 0.0 | 825 |
| LLPS-Poa-0587 | Pongo abelii | 97.37 | 0.0 | 777 |
| LLPS-Anp-0236 | Anas platyrhynchos | 97.2 | 0.0 | 827 |
| LLPS-Loa-0067 | Loxodonta africana | 97.2 | 0.0 | 830 |
| LLPS-Pes-0269 | Pelodiscus sinensis | 97.2 | 0.0 | 827 |
| LLPS-Gaga-1674 | Gallus gallus | 97.19 | 0.0 | 830 |
| LLPS-Tag-0246 | Taeniopygia guttata | 97.19 | 0.0 | 830 |
| LLPS-Sah-2646 | Sarcophilus harrisii | 96.97 | 0.0 | 822 |
| LLPS-Mup-3584 | Mustela putorius furo | 96.37 | 0.0 | 778 |
| LLPS-Anc-1487 | Anolis carolinensis | 95.32 | 0.0 | 825 |
| LLPS-Ran-0046 | Rattus norvegicus | 94.85 | 0.0 | 811 |
| LLPS-Lac-1682 | Latimeria chalumnae | 93.21 | 0.0 | 805 |
| LLPS-Ora-3489 | Ornithorhynchus anatinus | 91.36 | 0.0 | 743 |
| LLPS-Bot-3844 | Bos taurus | 90.87 | 0.0 | 790 |
| LLPS-Urm-0196 | Ursus maritimus | 90.63 | 0.0 | 789 |
| LLPS-Fia-2071 | Ficedula albicollis | 90.16 | 0.0 | 783 |
| LLPS-Xim-0084 | Xiphophorus maculatus | 90.03 | 0.0 | 732 |
| LLPS-Tar-0961 | Takifugu rubripes | 90.03 | 0.0 | 731 |
| LLPS-Caf-4240 | Canis familiaris | 89.7 | 0.0 | 780 |
| LLPS-Cas-3988 | Carlito syrichta | 89.7 | 0.0 | 780 |
| LLPS-Rhb-2527 | Rhinopithecus bieti | 89.7 | 0.0 | 781 |
| LLPS-Chs-3688 | Chlorocebus sabaeus | 89.7 | 0.0 | 781 |
| LLPS-Cea-3887 | Cercocebus atys | 89.7 | 0.0 | 780 |
| LLPS-Leo-3460 | Lepisosteus oculatus | 88.58 | 0.0 | 769 |
| LLPS-Dar-3841 | Danio rerio | 87.36 | 0.0 | 767 |
| LLPS-Scf-3946 | Scleropages formosus | 87.16 | 0.0 | 766 |
| LLPS-Asm-2019 | Astyanax mexicanus | 86.65 | 0.0 | 764 |
| LLPS-Cis-1640 | Ciona savignyi | 79.59 | 4e-109 | 336 |
| LLPS-Pof-1810 | Poecilia formosa | 50.7 | 4e-110 | 336 |
| LLPS-Orn-0239 | Oreochromis niloticus | 50.7 | 3e-118 | 356 |
| LLPS-Cae-1703 | Caenorhabditis elegans | 50.41 | 5e-120 | 362 |
| LLPS-Ten-0041 | Tetraodon nigroviridis | 50.28 | 6e-118 | 356 |
| LLPS-Scm-3750 | Scophthalmus maximus | 50.14 | 3e-117 | 354 |
| LLPS-Orl-1411 | Oryzias latipes | 50.0 | 2e-112 | 342 |
| LLPS-Icp-3182 | Ictalurus punctatus | 50.0 | 2e-112 | 342 |
| LLPS-Gaa-2747 | Gasterosteus aculeatus | 49.18 | 5e-111 | 338 |
| LLPS-Xet-2512 | Xenopus tropicalis | 48.48 | 2e-110 | 336 |
| LLPS-Drm-0463 | Drosophila melanogaster | 46.56 | 9e-108 | 330 |
| LLPS-Tut-1878 | Tursiops truncatus | 46.3 | 2e-107 | 329 |