• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mup-3584
MAPK8

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Mitogen-activated protein kinase
Gene Name: MAPK8
Ensembl Gene: ENSMPUG00000009129.1
Ensembl Protein: ENSMPUP00000009054.1
Organism: Mustela putorius furo
Taxa ID: 9669
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, Neuronal granule, P-body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSRSKRDSNF  YSVEIGDSTF  TVLKRYQNLK  PIGSGAQGIV  CAAYDAILER  NVAIKKLSRP  60
61    FQNQTHAKRA  YRELVLMKCV  NHKNIIGLLN  VFTPQKSLEE  FQDVYIVMEL  MDANLCQVIQ  120
121   MELDHERMSY  LLYQMLCGIK  HLHSAGIIHR  DLKPSNIVVK  SDCTLKILDF  GLARTAGTSF  180
181   MMTPYVVTRY  YRAPEVILGM  GYKENVDLWS  VGCIMGEMVC  HKILFPGRDY  IDQWNKVIEQ  240
241   LGTPCPEFMK  KLQPTVRTYV  ENRPKYAGYS  FEKLFPDVLF  PADSEHNKLK  ASQARDLLSK  300
301   MLVIDASKRI  SVDEALQHPY  INVWYDPSEA  EAPPPKIPDK  QLDEREHTIE  EWKELIYKEV  360
361   MDLEERTKNG  VIRGQPSPLA  QGTPNSRDHG  WESQMGH  397
Nucleotide CDS Sequence (FASTA)
1     ATGAGCAGAA  GCAAGCGTGA  CAGCAATTTT  TATAGTGTAG  AGATTGGAGA  TTCTACATTT  60
61    ACAGTCTTGA  AACGATATCA  GAATTTAAAA  CCTATAGGCT  CAGGAGCTCA  AGGAATAGTA  120
121   TGTGCAGCTT  ATGATGCCAT  TCTTGAAAGA  AATGTTGCAA  TCAAGAAGCT  AAGCCGGCCA  180
181   TTTCAGAACC  AGACTCATGC  TAAACGGGCT  TACAGAGAGC  TAGTTCTTAT  GAAATGTGTT  240
241   AATCACAAAA  ATATAATTGG  CCTTTTGAAT  GTTTTCACAC  CACAGAAATC  CCTAGAAGAA  300
301   TTTCAAGATG  TTTACATAGT  CATGGAGCTC  ATGGATGCAA  ATCTTTGCCA  AGTGATTCAG  360
361   ATGGAACTAG  ATCATGAGAG  AATGTCCTAC  CTTCTCTATC  AGATGCTGTG  TGGAATCAAG  420
421   CACCTTCACT  CTGCTGGAAT  TATTCATCGG  GACTTAAAGC  CCAGTAATAT  CGTGGTAAAA  480
481   TCAGACTGCA  CTTTGAAGAT  TCTTGACTTT  GGACTGGCCA  GGACTGCAGG  AACTAGTTTT  540
541   ATGATGACAC  CTTACGTAGT  GACTCGCTAC  TACAGAGCAC  CTGAGGTCAT  CCTAGGGATG  600
601   GGCTACAAAG  AAAACGTGGA  TTTATGGTCT  GTGGGGTGCA  TTATGGGAGA  AATGGTTTGC  660
661   CACAAAATCC  TCTTTCCAGG  AAGGGACTAT  ATTGATCAGT  GGAATAAAGT  TATTGAACAG  720
721   CTTGGAACAC  CATGCCCTGA  ATTCATGAAG  AAACTACAGC  CAACAGTAAG  GACTTATGTT  780
781   GAAAACAGAC  CTAAATATGC  TGGATATAGC  TTTGAGAAAC  TCTTCCCCGA  TGTACTTTTC  840
841   CCAGCTGACT  CAGAACACAA  CAAACTTAAA  GCCAGTCAGG  CAAGGGATTT  GTTATCCAAA  900
901   ATGCTGGTAA  TTGATGCATC  TAAAAGGATT  TCTGTAGATG  AAGCTCTCCA  GCACCCATAT  960
961   ATCAATGTCT  GGTATGATCC  TTCTGAAGCA  GAAGCTCCAC  CACCAAAGAT  ACCTGACAAG  1020
1021  CAGTTAGATG  AAAGGGAACA  TACAATAGAA  GAATGGAAAG  AGTTGATATA  CAAAGAAGTT  1080
1081  ATGGACTTGG  AGGAGAGAAC  CAAGAATGGA  GTTATAAGGG  GACAGCCCTC  TCCTTTAGCA  1140
1141  CAGGGGACCC  CTAACTCAAG  GGACCATGGG  TGGGAGTCTC  AAATGGGCCA  CTGA  1194

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mam-1700Macaca mulatta99.740.0 796
LLPS-Poa-0587Pongo abelii99.740.0 796
LLPS-Cap-2762Cavia porcellus99.470.0 791
LLPS-Sah-2646Sarcophilus harrisii98.180.0 787
LLPS-Aim-3341Ailuropoda melanoleuca97.940.0 797
LLPS-Myl-3011Myotis lucifugus97.940.0 799
LLPS-Ict-2905Ictidomys tridecemlineatus97.690.0 795
LLPS-Loa-0067Loxodonta africana97.690.0 793
LLPS-Hos-1461Homo sapiens97.690.0 795
LLPS-Otg-1816Otolemur garnettii97.690.0 795
LLPS-Paa-0139Papio anubis97.690.0 795
LLPS-Mal-0743Mandrillus leucophaeus97.690.0 795
LLPS-Sus-3897Sus scrofa97.690.0 795
LLPS-Mea-1725Mesocricetus auratus97.690.0 797
LLPS-Caj-3307Callithrix jacchus97.690.0 795
LLPS-Mod-2184Monodelphis domestica97.640.0 780
LLPS-Tag-0246Taeniopygia guttata97.430.0 794
LLPS-Gaga-1674Gallus gallus97.430.0 794
LLPS-Ova-3892Ovis aries97.370.0 777
LLPS-Aon-1530Aotus nancymaae97.370.0 773
LLPS-Pes-0269Pelodiscus sinensis97.190.0 791
LLPS-Anp-0236Anas platyrhynchos96.930.0 790
LLPS-Dio-2076Dipodomys ordii96.610.0 775
LLPS-Fud-2168Fukomys damarensis96.610.0 775
LLPS-Orc-2570Oryctolagus cuniculus96.340.0 774
LLPS-Eqc-1347Equus caballus95.890.0 780
LLPS-Fec-1857Felis catus95.890.0 780
LLPS-Nol-2848Nomascus leucogenys95.630.0 779
LLPS-Man-2362Macaca nemestrina95.630.0 779
LLPS-Pat-1543Pan troglodytes95.630.0 779
LLPS-Pap-2454Pan paniscus95.630.0 779
LLPS-Maf-1240Macaca fascicularis95.630.0 779
LLPS-Mum-4526Mus musculus95.630.0 780
LLPS-Gog-1946Gorilla gorilla95.630.0 779
LLPS-Meg-1938Meleagris gallopavo95.370.0 778
LLPS-Ran-0046Rattus norvegicus94.340.0 767
LLPS-Anc-1487Anolis carolinensis93.770.0 759
LLPS-Fia-2071Ficedula albicollis92.860.0 744
LLPS-Ora-3489Ornithorhynchus anatinus92.860.0 744
LLPS-Caf-4240Canis familiaris92.330.0 741
LLPS-Cas-3988Carlito syrichta92.330.0 741
LLPS-Rhb-2527Rhinopithecus bieti92.330.0 741
LLPS-Cea-3887Cercocebus atys92.330.0 741
LLPS-Chs-3688Chlorocebus sabaeus92.330.0 742
LLPS-Tar-0961Takifugu rubripes91.80.0 736
LLPS-Xim-0084Xiphophorus maculatus91.80.0 737
LLPS-Leo-3460Lepisosteus oculatus91.320.0 732
LLPS-Bot-3844Bos taurus90.740.0 732
LLPS-Urm-0196Ursus maritimus90.480.0 731
LLPS-Dar-3841Danio rerio89.90.0 731
LLPS-Lac-1682Latimeria chalumnae89.720.0 743
LLPS-Scf-3946Scleropages formosus89.660.0 730
LLPS-Asm-2019Astyanax mexicanus84.720.0 700
LLPS-Cis-1640Ciona savignyi78.03e-109 335
LLPS-Orn-0239Oreochromis niloticus49.866e-116 349
LLPS-Cae-1703Caenorhabditis elegans49.861e-120 362
LLPS-Scm-3750Scophthalmus maximus49.582e-115 348
LLPS-Pof-3734Poecilia formosa49.588e-116 349
LLPS-Icp-1119Ictalurus punctatus49.445e-107 328
LLPS-Ten-0041Tetraodon nigroviridis49.32e-115 349
LLPS-Orl-1411Oryzias latipes48.931e-109 333
LLPS-Xet-2512Xenopus tropicalis48.25e-109 332
LLPS-Gaa-3459Gasterosteus aculeatus48.033e-111 337
LLPS-Tut-1878Tursiops truncatus46.247e-105 321
LLPS-Drm-0463Drosophila melanogaster45.451e-104 321