LLPS-Mum-3125
Kpna7

▼ OVERVIEW

Status: Unreviewed
Protein Name: Importin subunit alpha-8; Karyopherin subunit alpha-7
Gene Name: Kpna7
Ensembl Gene: ENSMUSG00000038770.17
Ensembl Protein: ENSMUSP00000112155.3
Organism: Mus musculus
Taxa ID: 10090
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Functions in nuclear protein import.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MATSKAPKER  LKNYKYRGKE  MSLPRQQRIA  SSLQLRKTRK  DEQVLKRRNI  DLFSSDMVSQ  60
61    ALVKEVNFTL  DDIIQAVNSS  DPILHFRATR  AAREMISQEN  TPPLNLIIEA  GLIPKLVDFL  120
121   KATPHPKLQF  EAAWVLTNIA  SGTSEQTRAV  VKEGAIQPLI  ELLCSPHLTV  SEQAVWALGN  180
181   IADRKMPDTQ  VQIFTPSTRE  AKAGDCAEFR  DCVISNNAIP  HLINLISKGI  PITFLRNISW  240
241   TLSNLCRNKD  PYPSESAVRQ  MLPPLCQLLL  HRDNEILADT  CWALSYLTKG  GKEYIHHVVT  300
301   TGILPRLVEL  MTSSELSISI  PCLHTIGNIV  AGTDEQTQMA  IDAGMLKVLG  QVLKHPKTSI  360
361   QVLAAWTMSN  VAAGPRHQVE  QLLCNLLPIL  VDLLRNAELK  VQKEVVCTVI  NIATGASQDQ  420
421   LTLLAHSGIL  EPMLSLLSAP  DLEVVIIVLD  IISYLLQHID  NLQEKKRLYF  QIEKFGGFEK  480
481   IECLQHHHNI  SISNSALDII  EKYFCEDGDG  DSLPGPGLRV  520
Nucleotide CDS Sequence (FASTA)
1     ATGGCTACCT  CAAAGGCTCC  CAAAGAGAGG  CTGAAGAACT  ATAAGTACCG  AGGCAAAGAA  60
61    ATGTCATTGC  CACGACAACA  GAGGATTGCT  TCCAGTCTAC  AACTCCGGAA  GACCAGGAAA  120
121   GATGAGCAGG  TGCTAAAGAG  AAGAAATATC  GATCTGTTCT  CCAGTGACAT  GGTTTCTCAA  180
181   GCACTAGTCA  AAGAGGTCAA  CTTCACTCTG  GACGACATCA  TCCAAGCGGT  GAATAGTTCA  240
241   GATCCAATCC  TGCATTTTCG  GGCTACCCGG  GCTGCCAGGG  AAATGATCTC  GCAGGAAAAT  300
301   ACCCCTCCTC  TCAATTTGAT  TATTGAGGCC  GGGCTCATTC  CCAAGCTGGT  GGACTTCCTG  360
361   AAGGCGACAC  CTCACCCCAA  GCTGCAGTTC  GAGGCCGCAT  GGGTGCTCAC  CAACATTGCC  420
421   TCAGGAACTT  CAGAGCAGAC  CCGAGCTGTT  GTGAAAGAGG  GTGCCATTCA  GCCCCTGATT  480
481   GAACTCCTCT  GTTCCCCACA  CCTGACAGTG  TCTGAGCAGG  CAGTGTGGGC  CCTTGGGAAT  540
541   ATCGCTGGAG  ACTGTGCAGA  ATTCAGAGAC  TGTGTCATCT  CCAATAATGC  CATCCCACAC  600
601   CTGATCAACC  TTATTTCAAA  AGGCATACCA  ATCACATTTC  TTCGGAACAT  CTCATGGACT  660
661   TTGTCCAACT  TATGCCGAAA  CAAAGATCCA  TATCCCAGTG  AGAGCGCCGT  GCGGCAGATG  720
721   CTACCTCCCC  TCTGTCAACT  CCTGCTGCAT  CGTGATAATG  AGATCCTCGC  AGATACCTGC  780
781   TGGGCCCTGT  CCTACCTGAC  CAAGGGTGGC  AAAGAGTATA  TCCATCATGT  GGTGACCACT  840
841   GGCATCCTGC  CCAGGCTTGT  AGAGCTTATG  ACCAGCTCGG  AACTCAGCAT  CTCGATACCT  900
901   TGTCTCCACA  CTATAGGCAA  CATTGTGGCA  GGAACAGATG  AACAGACCCA  GATGGCTATC  960
961   GATGCTGGCA  TGCTGAAGGT  GTTGGGCCAG  GTCCTGAAGC  ACCCGAAGAC  CTCCATCCAG  1020
1021  GTGCTGGCTG  CCTGGACCAT  GAGCAACGTG  GCCGCTGGGC  CCAGACACCA  AGTGGAGCAG  1080
1081  CTTTTGTGTA  ACTTGCTGCC  TATTTTGGTA  GACCTACTAA  GGAATGCAGA  ATTAAAAGTC  1140
1141  CAGAAGGAGG  TTGTGTGCAC  TGTGATTAAC  ATTGCAACAG  GAGCCTCTCA  GGACCAGCTG  1200
1201  ACTCTGCTTG  CCCACTCGGG  AATCTTGGAG  CCAATGCTGA  GTCTGCTCTC  CGCCCCAGAC  1260
1261  TTGGAGGTGG  TCATCATCGT  CCTAGACATC  ATTTCTTATC  TCCTCCAGCA  TATAGACAAT  1320
1321  CTACAAGAGA  AGAAAAGGCT  GTATTTTCAG  ATAGAAAAAT  TTGGTGGCTT  TGAAAAAATT  1380
1381  GAGTGTTTAC  AGCACCACCA  CAACATTTCC  ATCAGCAATA  GCGCCCTGGA  CATCATCGAG  1440
1441  AAATACTTCT  GTGAGGATGG  AGATGGTGAC  AGTTTGCCCG  GGCCTGGGCT  GAGAGTGTGA  1500

▼ KEYWORD

ID
Family
Alternative splicing
Complete proteome
Nucleus
Protein transport
Reference proteome
Repeat
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Molecular Function
Nuclear import signal receptor activity
Molecular Function
Protein transporter activity
Biological Process
Protein import into nucleus

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ran-2474Rattus norvegicus78.30.0 765
LLPS-Otg-3447Otolemur garnettii62.130.0 607
LLPS-Caf-3994Canis familiaris61.930.0 599
LLPS-Aim-3687Ailuropoda melanoleuca61.740.0 602
LLPS-Orc-0773Oryctolagus cuniculus61.140.0 574
LLPS-Nol-0568Nomascus leucogenys60.90.0 582
LLPS-Poa-4407Pongo abelii60.710.0 583
LLPS-Ere-0808Erinaceus europaeus60.72e-146 432
LLPS-Pat-4163Pan troglodytes60.510.0 582
LLPS-Pap-4025Pan paniscus60.510.0 583
LLPS-Hos-2361Homo sapiens60.510.0 583
LLPS-Gog-3228Gorilla gorilla60.510.0 582
LLPS-Rhb-2481Rhinopithecus bieti60.430.0 562
LLPS-Fec-2329Felis catus60.360.0 587
LLPS-Chs-1470Chlorocebus sabaeus60.290.0 530
LLPS-Mam-1702Macaca mulatta60.240.0 555
LLPS-Paa-2594Papio anubis60.240.0 558
LLPS-Mup-4384Mustela putorius furo60.160.0 590
LLPS-Eqc-2506Equus caballus60.120.0 580
LLPS-Maf-0665Macaca fascicularis60.040.0 554
LLPS-Man-1010Macaca nemestrina59.840.0 552
LLPS-Mal-0629Mandrillus leucophaeus59.840.0 552
LLPS-Cea-4244Cercocebus atys59.840.0 553
LLPS-Fud-2280Fukomys damarensis59.170.0 562
LLPS-Aon-3740Aotus nancymaae58.940.0 569
LLPS-Caj-3833Callithrix jacchus58.550.0 565
LLPS-Loa-1233Loxodonta africana58.380.0 550
LLPS-Cap-3774Cavia porcellus58.010.0 563
LLPS-Myl-1791Myotis lucifugus57.790.0 550
LLPS-Bot-4100Bos taurus57.790.0 561
LLPS-Ova-3872Ovis aries57.70.0 550
LLPS-Sus-4246Sus scrofa57.590.0 548
LLPS-Dio-2669Dipodomys ordii57.570.0 555
LLPS-Ict-1397Ictidomys tridecemlineatus55.230.0 531
LLPS-Urm-2440Ursus maritimus53.163e-165 484
LLPS-Ora-1990Ornithorhynchus anatinus52.789e-176 512
LLPS-Mod-3035Monodelphis domestica51.282e-172 504
LLPS-Lac-0280Latimeria chalumnae48.731e-151 451
LLPS-Leo-1361Lepisosteus oculatus48.613e-143 430
LLPS-Icp-0460Ictalurus punctatus48.064e-132 400
LLPS-Cas-0743Carlito syrichta47.974e-133 402
LLPS-Scf-1898Scleropages formosus46.051e-141 427
LLPS-Ten-0697Tetraodon nigroviridis46.03e-142 427
LLPS-Gaga-1383Gallus gallus45.547e-144 432
LLPS-Anp-0346Anas platyrhynchos45.541e-141 426
LLPS-Meg-2119Meleagris gallopavo45.542e-144 433
LLPS-Anc-1579Anolis carolinensis45.352e-141 425
LLPS-Tag-1745Taeniopygia guttata45.216e-143 429
LLPS-Pes-0806Pelodiscus sinensis45.153e-141 425
LLPS-Asm-1298Astyanax mexicanus44.972e-139 420
LLPS-Fia-1452Ficedula albicollis44.814e-141 426
LLPS-Sah-0458Sarcophilus harrisii44.818e-140 421
LLPS-Dar-0438Danio rerio44.755e-144 432
LLPS-Xim-0268Xiphophorus maculatus44.699e-136 410
LLPS-Orl-2043Oryzias latipes44.41e-137 416
LLPS-Pof-3741Poecilia formosa44.295e-136 411
LLPS-Xet-1957Xenopus tropicalis44.072e-139 421
LLPS-Tar-0586Takifugu rubripes43.315e-137 414
LLPS-Orn-3891Oreochromis niloticus43.39e-134 405
LLPS-Scm-1340Scophthalmus maximus43.145e-135 409
LLPS-Gaa-0738Gasterosteus aculeatus42.831e-135 410
LLPS-Tut-0366Tursiops truncatus41.032e-112 350
LLPS-Drm-0244Drosophila melanogaster39.294e-101 321
LLPS-Mea-2049Mesocricetus auratus38.973e-101 321
LLPS-Cii-1592Ciona intestinalis38.942e-108 340
LLPS-Nia-0168Nicotiana attenuata38.582e-99 317
LLPS-Sot-0788Solanum tuberosum38.096e-99 316
LLPS-Brn-0214Brassica napus37.913e-99 317
LLPS-Arl-1579Arabidopsis lyrata37.785e-100 318
LLPS-Art-0129Arabidopsis thaliana37.13e-99 317
LLPS-Gas-0099Galdieria sulphuraria36.781e-101 322
LLPS-Cae-0053Caenorhabditis elegans36.712e-100 319
LLPS-Ast-0980Aspergillus terreus36.141e-99 318