• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mua-0905
PFK

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: ATP-dependent 6-phosphofructokinase
Gene Name: PFK
Ensembl Gene: GSMUA_Achr1G21680_001
Ensembl Protein: GSMUA_Achr1P21680_001
Organism: Musa acuminata
Taxa ID: 214687
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblGSMUA_Achr1T21680_001GSMUA_Achr1P21680_001
UniProtM0S1X6, M0S1X6_MUSAM

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTNPRPIVVK  PEIDFNDPDW  KKKFLEDFDK  RFNLPHLRDV  LDIQPRPTTF  SLKTRGTLEV  60
61    GNGAAREDWN  GFVSDDDRAL  LKVIKFASPT  SAGAESIDPD  CSWVEQWVHR  AGPRKQIYYE  120
121   PREVKAAIVT  CGGLCPGLND  VIRQIVLTLE  KYGVKNIVGI  PYGFRGFSDE  GLSEVPLSRQ  180
181   VVQNINLTGG  SFLGVSRGGP  STSDIVDNIQ  AKRIDMLFVL  GGDGTHAGAL  AIHNECRLRK  240
241   LKVSIVCVAK  TIDNDILLMD  KTFGFDTAVE  EAQRAINSAY  IEARSAYHGI  GLVKLMGRSS  300
301   GFIAMHASLS  SGQIDICLIP  EAPFKLEGPN  GVLVHLEYLL  KTKGNAVICV  AEGAGQEYLK  360
361   KSNTTDASGN  VVLSDIGVHV  QQQIKRHFKD  VGIPADVKYI  DPTYMIRACR  ANASDAILCT  420
421   VLGQNAVHGA  FAGFSGITTG  ICNTHFVYFP  VTEVIASTRY  VDPNSRMWHR  CLTSTGQPDF  480
481   E  481
Nucleotide CDS Sequence (FASTA)
1     ATGACAAATC  CTAGACCAAT  TGTTGTTAAA  CCAGAAATTG  ACTTTAATGA  TCCAGACTGG  60
61    AAAAAAAAAT  TCCTAGAGGA  TTTTGATAAG  CGGTTCAATT  TACCACATTT  GAGGGATGTT  120
121   CTGGATATTC  AGCCAAGGCC  AACTACATTC  TCACTCAAAA  CCAGAGGTAC  TTTAGAAGTT  180
181   GGTAATGGTG  CAGCAAGAGA  AGATTGGAAT  GGCTTTGTGA  GTGATGATGA  TAGAGCACTT  240
241   CTGAAGGTTA  TAAAATTTGC  TTCCCCAACT  TCTGCTGGTG  CTGAGAGCAT  TGACCCTGAT  300
301   TGCAGCTGGG  TAGAACAATG  GGTGCACCGT  GCTGGACCAC  GTAAGCAAAT  ATACTATGAA  360
361   CCGAGGGAGG  TAAAAGCTGC  AATTGTTACT  TGTGGAGGGC  TTTGTCCTGG  TCTCAATGAT  420
421   GTAATTAGGC  AGATAGTGCT  CACACTTGAA  AAATATGGGG  TAAAAAATAT  TGTTGGAATT  480
481   CCATATGGTT  TCCGTGGATT  TTCTGATGAG  GGATTATCTG  AAGTGCCGCT  TTCGCGTCAA  540
541   GTGGTTCAAA  ATATTAACCT  CACTGGTGGA  AGTTTTCTAG  GAGTATCCCG  AGGAGGTCCC  600
601   AGCACCAGTG  ATATAGTTGA  TAACATCCAG  GCCAAGAGAA  TTGATATGCT  TTTTGTACTG  660
661   GGCGGAGATG  GGACACATGC  AGGGGCACTT  GCCATACATA  ATGAGTGCCG  CTTGAGAAAA  720
721   TTGAAAGTAT  CAATTGTCTG  TGTTGCAAAA  ACTATTGACA  ATGACATACT  ACTAATGGAC  780
781   AAAACATTTG  GTTTTGACAC  TGCTGTAGAG  GAAGCTCAGC  GGGCAATCAA  TTCCGCATAT  840
841   ATTGAGGCTC  GTAGTGCTTA  CCATGGCATT  GGATTGGTCA  AATTGATGGG  AAGAAGCAGT  900
901   GGGTTTATAG  CCATGCATGC  ATCACTTTCT  AGTGGTCAAA  TTGACATTTG  TTTGATTCCC  960
961   GAGGCACCTT  TTAAATTGGA  GGGGCCAAAT  GGAGTCTTAG  TGCATCTCGA  GTATCTGCTG  1020
1021  AAAACAAAGG  GAAATGCTGT  AATTTGTGTT  GCTGAAGGAG  CAGGACAAGA  ATACCTAAAG  1080
1081  AAGTCGAATA  CAACAGATGC  ATCAGGGAAT  GTGGTTCTCA  GTGATATTGG  AGTTCATGTT  1140
1141  CAGCAGCAGA  TCAAAAGACA  TTTCAAGGAT  GTAGGCATTC  CAGCAGATGT  GAAATACATT  1200
1201  GATCCAACCT  ATATGATCCG  AGCTTGCCGT  GCCAATGCGT  CTGATGCAAT  CCTCTGCACT  1260
1261  GTCCTAGGCC  AGAATGCTGT  ACATGGTGCA  TTTGCTGGGT  TCAGTGGCAT  CACAACAGGT  1320
1321  ATATGCAATA  CACATTTTGT  CTACTTTCCT  GTTACAGAGG  TCATTGCATC  TACCAGGTAT  1380
1381  GTAGACCCGA  ACAGTAGGAT  GTGGCACCGA  TGCCTGACAT  CCACTGGCCA  ACCTGACTTC  1440
1441  GAATGA  1446

▼ KEYWORD

ID
Family
Allosteric enzyme
ATP-binding
Complete proteome
Cytoplasm
Glycolysis
Kinase
Magnesium
Metal-binding
Nucleotide-binding
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
6-phosphofructokinase activity
Molecular Function
ATP binding
Molecular Function
Metal ion binding
Biological Process
Fructose 6-phosphate metabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Amt-2312Amborella trichopoda78.220.0 785
LLPS-Viv-1241Vitis vinifera78.090.0 778
LLPS-Thc-1815Theobroma cacao74.580.0 751
LLPS-Gor-2670Gossypium raimondii74.360.0 751
LLPS-Via-2288Vigna angularis73.990.0 736
LLPS-Mae-2393Manihot esculenta73.840.0 747
LLPS-Phv-2182Phaseolus vulgaris73.730.0 741
LLPS-Glm-1540Glycine max73.730.0 742
LLPS-Pot-1922Populus trichocarpa73.570.0 749
LLPS-Sol-0908Solanum lycopersicum73.380.0 750
LLPS-Met-1419Medicago truncatula73.360.0 739
LLPS-Nia-2098Nicotiana attenuata73.310.0 735
LLPS-Arl-2328Arabidopsis lyrata72.610.0 734
LLPS-Dac-2317Daucus carota72.540.0 691
LLPS-Sot-2248Solanum tuberosum72.540.0 741
LLPS-Art-3039Arabidopsis thaliana72.40.0 731
LLPS-Prp-0243Prunus persica72.30.0 745
LLPS-Coc-0112Corchorus capsularis72.250.0 738
LLPS-Brn-2698Brassica napus71.340.0 726
LLPS-Bro-0453Brassica oleracea71.130.0 724
LLPS-Vir-2113Vigna radiata70.990.0 736
LLPS-Brr-2891Brassica rapa69.30.0 691
LLPS-Php-0236Physcomitrella patens68.260.0 659
LLPS-Sem-1118Selaginella moellendorffii62.639e-171 496
LLPS-Osl-1292Ostreococcus lucimarinus55.939e-148 437
LLPS-Lep-1767Leersia perrieri53.854e-129 392
LLPS-Ors-1378Oryza sativa53.584e-128 390
LLPS-Orr-0831Oryza rufipogon53.584e-128 390
LLPS-Org-1039Oryza glaberrima53.584e-128 390
LLPS-Tru-0487Triticum urartu53.585e-129 392
LLPS-Orb-1034Oryza barthii53.584e-128 390
LLPS-Ori-0655Oryza indica53.584e-128 390
LLPS-Orni-0591Oryza nivara53.584e-128 390
LLPS-Hov-2159Hordeum vulgare53.584e-129 392
LLPS-Orgl-0692Oryza glumaepatula53.321e-127 388
LLPS-Tra-1810Triticum aestivum53.321e-128 391
LLPS-Orp-1330Oryza punctata53.192e-124 381
LLPS-Orbr-0719Oryza brachyantha52.86e-125 384
LLPS-Sob-1961Sorghum bicolor52.82e-124 380
LLPS-Zem-2480Zea mays52.86e-125 382
LLPS-Sei-1924Setaria italica52.537e-123 379
LLPS-Cus-1362Cucumis sativus52.388e-131 394
LLPS-Hea-1248Helianthus annuus52.121e-127 387
LLPS-Orm-1308Oryza meridionalis51.62e-123 380
LLPS-Brd-1915Brachypodium distachyon51.332e-120 378
LLPS-Gas-1104Galdieria sulphuraria51.22e-133 403
LLPS-Chc-1089Chondrus crispus50.132e-121 373
LLPS-Cym-0836Cyanidioschyzon merolae43.982e-126 384
LLPS-Put-0611Puccinia triticina30.299e-0755.8
LLPS-Xim-4111Xiphophorus maculatus27.875e-1066.2
LLPS-Cae-0984Caenorhabditis elegans27.662e-1170.5
LLPS-Scm-0523Scophthalmus maximus27.552e-1479.7
LLPS-Gaa-2531Gasterosteus aculeatus27.554e-1582.4
LLPS-Dar-1019Danio rerio27.521e-0965.1
LLPS-Pof-3822Poecilia formosa27.469e-1065.1
LLPS-Orn-2342Oreochromis niloticus27.41e-0758.2
LLPS-Caj-4305Callithrix jacchus27.391e-0653.5
LLPS-Urm-3158Ursus maritimus27.352e-0860.8
LLPS-Asf-1112Aspergillus flavus27.01e-1274.3
LLPS-Sah-2879Sarcophilus harrisii26.949e-1065.5
LLPS-Aso-1342Aspergillus oryzae26.731e-1274.3
LLPS-Gog-2307Gorilla gorilla26.691e-0862.0
LLPS-Maf-3368Macaca fascicularis26.552e-0758.2
LLPS-Paa-2942Papio anubis26.551e-0758.5
LLPS-Abg-0238Absidia glauca26.493e-1273.2
LLPS-Cog-0759Colletotrichum gloeosporioides26.454e-0653.5
LLPS-Asm-2203Astyanax mexicanus26.411e-0862.0
LLPS-Ast-0349Aspergillus terreus26.38e-1271.6
LLPS-Orl-3989Oryzias latipes26.292e-0654.7
LLPS-Sac-0201Saccharomyces cerevisiae26.269e-1581.3
LLPS-Fud-4456Fukomys damarensis26.252e-0963.9
LLPS-Kop-1480Komagataella pastoris26.191e-1584.3
LLPS-Leo-1200Lepisosteus oculatus26.144e-1169.7
LLPS-Mal-2659Mandrillus leucophaeus26.118e-0755.8
LLPS-Scc-0468Schizosaccharomyces cryophilus26.094e-0860.1
LLPS-Meg-1133Meleagris gallopavo26.035e-0859.7
LLPS-Pes-2933Pelodiscus sinensis26.021e-0964.7
LLPS-Dio-4205Dipodomys ordii25.838e-1168.6
LLPS-Usm-1259Ustilago maydis25.821e-0862.0
LLPS-Caf-0713Canis familiaris25.713e-1067.0
LLPS-Ora-0863Ornithorhynchus anatinus25.711e-0758.5
LLPS-Poa-3391Pongo abelii25.678e-0755.8
LLPS-Anc-2842Anolis carolinensis25.69e-1065.5
LLPS-Tar-3767Takifugu rubripes25.596e-1375.5
LLPS-Bot-3173Bos taurus25.587e-1168.9
LLPS-Map-0973Magnaporthe poae25.532e-0861.2
LLPS-Pytr-1140Pyrenophora triticirepentis25.57e-0652.8
LLPS-Mam-0948Macaca mulatta25.451e-0758.2
LLPS-Cas-1179Carlito syrichta25.311e-0964.7
LLPS-Aon-4656Aotus nancymaae25.315e-0963.2
LLPS-Asni-0090Aspergillus niger25.283e-1169.7
LLPS-Asc-0084Aspergillus clavatus25.272e-1273.9
LLPS-Ten-2750Tetraodon nigroviridis25.213e-1169.7
LLPS-Myl-3619Myotis lucifugus25.22e-0964.3
LLPS-Asg-0716Ashbya gossypii25.196e-0962.8
LLPS-Icp-2024Ictalurus punctatus25.145e-1272.4
LLPS-Eqc-1916Equus caballus25.085e-0653.1
LLPS-Gaga-2424Gallus gallus25.077e-1168.9
LLPS-Man-4011Macaca nemestrina25.04e-1272.8
LLPS-Chs-4099Chlorocebus sabaeus25.05e-1272.4
LLPS-Asn-1372Aspergillus nidulans24.921e-1170.9
LLPS-Nef-1245Neosartorya fischeri24.915e-1169.3
LLPS-Pat-4530Pan troglodytes24.91e-0861.6
LLPS-Hos-4968Homo sapiens24.91e-0861.6
LLPS-Fec-0079Felis catus24.97e-1065.9
LLPS-Aim-0056Ailuropoda melanoleuca24.861e-1068.2
LLPS-Mel-1375Melampsora laricipopulina24.849e-0858.9
LLPS-Pap-2887Pan paniscus24.722e-1170.9
LLPS-Scf-2914Scleropages formosus24.726e-1169.3
LLPS-Spr-0794Sporisorium reilianum24.672e-1067.4
LLPS-Ict-3662Ictidomys tridecemlineatus24.593e-1067.0
LLPS-Lem-1131Leptosphaeria maculans24.465e-1169.7
LLPS-Dos-0945Dothistroma septosporum24.435e-0859.7
LLPS-Fia-1639Ficedula albicollis24.424e-1066.6
LLPS-Cap-2401Cavia porcellus24.313e-1067.0
LLPS-Mea-3354Mesocricetus auratus24.311e-0964.7
LLPS-Mum-4455Mus musculus24.316e-1065.9
LLPS-Ran-2738Rattus norvegicus24.313e-1066.6
LLPS-Ova-1289Ovis aries24.316e-1065.9
LLPS-Mup-0465Mustela putorius furo24.319e-1065.5
LLPS-Otg-4170Otolemur garnettii24.041e-0862.0
LLPS-Nol-1703Nomascus leucogenys24.043e-1067.0
LLPS-Cea-1426Cercocebus atys24.047e-1065.5
LLPS-Sus-4399Sus scrofa24.041e-0861.6
LLPS-Loa-1417Loxodonta africana23.833e-0653.9
LLPS-Rhb-4328Rhinopithecus bieti23.778e-1065.5
LLPS-Orc-3475Oryctolagus cuniculus23.768e-1065.5
LLPS-Asfu-1419Aspergillus fumigatus23.657e-1168.9
LLPS-Phn-1026Phaeosphaeria nodorum23.43e-0963.5
LLPS-Xet-2537Xenopus tropicalis23.352e-0964.7