LLPS-Mam-0194
HTRA2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | HtrA serine peptidase 2 |
| Gene Name: | HTRA2, EGK_05477 |
| Ensembl Gene: | ENSMMUG00000002136.3 |
| Ensembl Protein: | ENSMMUP00000036442.2 |
| Organism: | Macaca mulatta |
| Taxa ID: | 9544 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMMUT00000043441.2 | ENSMMUP00000036442.2 |
| Ensembl | ENSMMUT00000003016.2 | ENSMMUP00000002848.2 |
| Ensembl | ENSMMUT00000003015.3 | ENSMMUP00000002847.2 |
| UniProt | F6UNR7, F6UNR7_MACMU, F6UNT9 | |
| GeneBank | JSUE03011238, JU475214, JU475212, JV045768, CM001265, JU475213 | , AFH32017.1, AFI35839.1, AFH32016.1, AFH32018.1, EHH22248.1 |
| RefSeq | NM_001258138.1 | NP_001245067.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAPRAGRGA GWSLRAWRAL GGIRWGRRPR LTPDLRALLT SGTSDPRARV TYGTPSLWAR 60 61 LCVGVPEPRA CLTSGTPGPR AQLTAVTPDT RTREASENSG TRSRAWLAVA LGAGGAVLLL 120 121 LWGGGRGPPA VLAAVPGPPP ASPRSQYNFI ADVVEKTAPA VVYIEILDRH PFLGREVPIS 180 181 NGSGFVVAAD GLIVTNAHVV ADRRRVRVRL LSGDTYEAVV TAVDPVADIA TLRIQTKEPL 240 241 PTLPLGRSAD VRQGEFVVAM GSPFALQNTI TSGIVSSAQR PARDLGLPQT NVEYIQTDAA 300 301 IDFGNSGGPL VNLDGEVIGV NTMKVTAGIS FAIPSDRLRE FLHRGEKKNS SSGISGSQRR 360 361 YIGVMMLTLS PSILAELQLR EPSFPDVQHG VLIHKVILGS PAHRAGLRPG DVILAIGGQM 420 421 VQNAEDVYEA VRTQSQLAVQ IRRGRETLTL YVTPEVTE 458 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGCGC CGAGGGCGGG GCGGGGTGCA GGCTGGAGCC TTCGGGCATG GCGGGCTTTG 60 61 GGGGGCATTC GCTGGGGGAG GAGACCCCGG TTGACCCCTG ACCTCCGGGC CCTGCTGACG 120 121 TCAGGAACTT CTGACCCCCG GGCCCGAGTG ACTTATGGGA CCCCCAGTCT CTGGGCCCGG 180 181 TTGTGTGTTG GGGTCCCTGA ACCCCGAGCA TGTCTGACGT CTGGGACCCC GGGTCCCCGG 240 241 GCACAACTGA CTGCGGTGAC CCCAGATACC AGGACCCGGG AGGCCTCAGA GAACTCTGGA 300 301 ACCCGTTCGC GCGCGTGGCT GGCTGTGGCA CTGGGCGCTG GGGGGGCAGT GCTGTTGTTG 360 361 TTGTGGGGCG GGGGTCGGGG TCCTCCGGCC GTCCTCGCCG CCGTCCCTGG CCCGCCGCCC 420 421 GCTTCTCCCC GGAGTCAGTA CAACTTCATC GCAGATGTGG TGGAGAAGAC AGCACCTGCC 480 481 GTGGTCTATA TCGAGATCCT GGACCGGCAC CCTTTCTTGG GCCGTGAAGT CCCTATCTCG 540 541 AACGGCTCAG GATTCGTGGT GGCTGCCGAT GGGCTCATTG TCACCAACGC CCATGTGGTG 600 601 GCTGATCGGC GCAGAGTCCG TGTGAGACTG CTTAGCGGCG ACACGTATGA GGCCGTGGTC 660 661 ACAGCTGTGG ATCCCGTGGC AGACATCGCA ACGCTGAGGA TTCAGACTAA GTTTGGGAAC 720 721 TCTGGAGGTC CCCTGGTTAA CCTGGATGGA GAGGTGATTG GAGTGAACAC CATGAAGGTC 780 781 ACAGCTGGAA TCTCCTTTGC CATCCCTTCT GATCGCCTTC GAGAGTTTCT GCATCGTGGG 840 841 GAAAAGAAGA ATTCCTCCTC TGGAATCAGT GGGTCCCAGC GGCGCTACAT TGGGGTGATG 900 901 ATGCTGACCC TGAGTCCCAG GGCTGGTCTG CGGCCTGGTG ATGTGATTTT GGCCATTGGG 960 961 GGGCAGATGG TACAAAATGC TGAAGATGTT TATGAAGCTG TTCGAACCCA ATCCCAGCTG 1020 1021 GCAGTGCAGA TCCGGCGGGG ACGAGAAACA CTGACCTTAT ATGTGACCCC TGAGGTCACA 1080 1081 GAATGA 1086 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Maf-4452 | Macaca fascicularis | 100.0 | 0.0 | 790 |
| LLPS-Man-1869 | Macaca nemestrina | 99.78 | 0.0 | 786 |
| LLPS-Chs-4120 | Chlorocebus sabaeus | 99.78 | 0.0 | 788 |
| LLPS-Paa-0835 | Papio anubis | 99.34 | 0.0 | 785 |
| LLPS-Cea-4113 | Cercocebus atys | 99.34 | 0.0 | 783 |
| LLPS-Pat-4341 | Pan troglodytes | 99.13 | 0.0 | 781 |
| LLPS-Poa-0459 | Pongo abelii | 98.91 | 0.0 | 775 |
| LLPS-Mup-1850 | Mustela putorius furo | 92.29 | 0.0 | 708 |
| LLPS-Ict-1637 | Ictidomys tridecemlineatus | 91.48 | 0.0 | 702 |
| LLPS-Orc-1396 | Oryctolagus cuniculus | 91.27 | 0.0 | 699 |
| LLPS-Aim-2959 | Ailuropoda melanoleuca | 91.05 | 0.0 | 704 |
| LLPS-Sus-3159 | Sus scrofa | 88.65 | 0.0 | 676 |
| LLPS-Caj-0778 | Callithrix jacchus | 88.43 | 0.0 | 691 |
| LLPS-Aon-2549 | Aotus nancymaae | 88.33 | 0.0 | 678 |
| LLPS-Myl-2506 | Myotis lucifugus | 87.55 | 0.0 | 668 |
| LLPS-Loa-4232 | Loxodonta africana | 86.24 | 0.0 | 679 |
| LLPS-Dar-1227 | Danio rerio | 70.7 | 5e-151 | 444 |
| LLPS-Icp-1288 | Ictalurus punctatus | 69.52 | 5e-147 | 434 |
| LLPS-Orl-0379 | Oryzias latipes | 68.79 | 5e-147 | 434 |
| LLPS-Gaa-1142 | Gasterosteus aculeatus | 68.47 | 8e-149 | 434 |
| LLPS-Scm-1970 | Scophthalmus maximus | 67.83 | 2e-144 | 428 |
| LLPS-Scf-1516 | Scleropages formosus | 67.2 | 1e-144 | 426 |
| LLPS-Asm-3041 | Astyanax mexicanus | 66.24 | 7e-142 | 421 |
| LLPS-Pof-1234 | Poecilia formosa | 65.61 | 4e-138 | 411 |
| LLPS-Orn-3530 | Oreochromis niloticus | 65.61 | 5e-144 | 422 |
| LLPS-Xim-2820 | Xiphophorus maculatus | 64.65 | 7e-138 | 411 |
| LLPS-Leo-3756 | Lepisosteus oculatus | 55.48 | 3e-109 | 338 |
| LLPS-Ten-3752 | Tetraodon nigroviridis | 54.84 | 2e-105 | 329 |
| LLPS-Lac-2940 | Latimeria chalumnae | 54.52 | 4e-108 | 335 |
| LLPS-Bot-3984 | Bos taurus | 54.52 | 2e-106 | 333 |
| LLPS-Ova-4224 | Ovis aries | 54.52 | 4e-109 | 333 |
| LLPS-Tar-2039 | Takifugu rubripes | 54.31 | 4e-108 | 335 |
| LLPS-Eqc-1188 | Equus caballus | 54.19 | 5e-105 | 330 |
| LLPS-Nol-2246 | Nomascus leucogenys | 54.19 | 4e-106 | 330 |
| LLPS-Anc-2210 | Anolis carolinensis | 54.19 | 3e-107 | 333 |
| LLPS-Cas-2415 | Carlito syrichta | 54.19 | 1e-106 | 329 |
| LLPS-Fec-1631 | Felis catus | 54.19 | 8e-106 | 330 |
| LLPS-Hos-4345 | Homo sapiens | 54.19 | 1e-105 | 329 |
| LLPS-Pap-3662 | Pan paniscus | 54.19 | 4e-105 | 328 |
| LLPS-Rhb-0233 | Rhinopithecus bieti | 54.19 | 9e-106 | 328 |
| LLPS-Fia-2910 | Ficedula albicollis | 54.19 | 2e-109 | 336 |
| LLPS-Tut-0244 | Tursiops truncatus | 54.19 | 3e-108 | 330 |
| LLPS-Mal-4372 | Mandrillus leucophaeus | 54.19 | 2e-107 | 331 |
| LLPS-Fud-2564 | Fukomys damarensis | 54.19 | 3e-107 | 330 |
| LLPS-Gog-3666 | Gorilla gorilla | 54.19 | 1e-105 | 329 |
| LLPS-Tag-1592 | Taeniopygia guttata | 53.87 | 3e-108 | 335 |
| LLPS-Urm-3157 | Ursus maritimus | 53.87 | 6e-106 | 327 |
| LLPS-Otg-1039 | Otolemur garnettii | 53.87 | 9e-106 | 330 |
| LLPS-Ran-3533 | Rattus norvegicus | 53.87 | 1e-105 | 329 |
| LLPS-Mum-4803 | Mus musculus | 53.87 | 1e-105 | 329 |
| LLPS-Mea-0588 | Mesocricetus auratus | 53.87 | 1e-105 | 329 |
| LLPS-Ere-0682 | Erinaceus europaeus | 53.7 | 3e-110 | 337 |
| LLPS-Caf-2677 | Canis familiaris | 53.55 | 6e-105 | 325 |
| LLPS-Anp-1913 | Anas platyrhynchos | 53.55 | 2e-108 | 331 |
| LLPS-Meg-2452 | Meleagris gallopavo | 53.55 | 2e-108 | 331 |
| LLPS-Dio-3744 | Dipodomys ordii | 53.53 | 3e-104 | 326 |
| LLPS-Xet-2904 | Xenopus tropicalis | 53.35 | 1e-108 | 337 |
| LLPS-Ora-2961 | Ornithorhynchus anatinus | 53.02 | 3e-72 | 234 |
| LLPS-Gaga-3711 | Gallus gallus | 53.0 | 2e-112 | 346 |
| LLPS-Mod-0576 | Monodelphis domestica | 52.37 | 9e-111 | 342 |
| LLPS-Pes-0040 | Pelodiscus sinensis | 52.26 | 2e-103 | 318 |
| LLPS-Drm-2089 | Drosophila melanogaster | 51.72 | 3e-93 | 295 |
| LLPS-Sah-4018 | Sarcophilus harrisii | 51.61 | 1e-100 | 316 |
| LLPS-Cap-1026 | Cavia porcellus | 50.8 | 4e-100 | 310 |
| LLPS-Cis-1974 | Ciona savignyi | 48.72 | 2e-88 | 282 |
| LLPS-Cii-1496 | Ciona intestinalis | 47.78 | 3e-86 | 274 |
| LLPS-Art-0669 | Arabidopsis thaliana | 44.06 | 2e-65 | 223 |
| LLPS-Brn-2354 | Brassica napus | 44.03 | 3e-64 | 219 |
| LLPS-Bro-2953 | Brassica oleracea | 43.89 | 1e-64 | 221 |
| LLPS-Tru-1528 | Triticum urartu | 43.85 | 6e-57 | 199 |
| LLPS-Arl-0636 | Arabidopsis lyrata | 43.85 | 6e-65 | 221 |
| LLPS-Gas-0249 | Galdieria sulphuraria | 43.69 | 1e-60 | 216 |
| LLPS-Orbr-1508 | Oryza brachyantha | 43.6 | 2e-62 | 214 |
| LLPS-Brd-0616 | Brachypodium distachyon | 43.6 | 9e-61 | 210 |
| LLPS-Hov-1233 | Hordeum vulgare | 43.6 | 5e-60 | 207 |
| LLPS-Amt-2078 | Amborella trichopoda | 43.3 | 1e-58 | 206 |
| LLPS-Nia-0645 | Nicotiana attenuata | 43.24 | 2e-60 | 209 |
| LLPS-Prp-1026 | Prunus persica | 43.01 | 1e-63 | 218 |
| LLPS-Ori-2145 | Oryza indica | 42.91 | 1e-60 | 211 |
| LLPS-Sei-0101 | Setaria italica | 42.37 | 3e-64 | 220 |
| LLPS-Mua-0105 | Musa acuminata | 42.28 | 4e-56 | 198 |
| LLPS-Tra-2570 | Triticum aestivum | 42.21 | 1e-58 | 204 |
| LLPS-Php-0632 | Physcomitrella patens | 42.16 | 2e-61 | 213 |
| LLPS-Mae-2375 | Manihot esculenta | 42.01 | 2e-62 | 215 |
| LLPS-Gor-2654 | Gossypium raimondii | 41.87 | 5e-60 | 208 |
| LLPS-Thc-1153 | Theobroma cacao | 41.69 | 5e-62 | 214 |
| LLPS-Sem-0232 | Selaginella moellendorffii | 41.64 | 3e-57 | 199 |
| LLPS-Cym-0280 | Cyanidioschyzon merolae | 41.5 | 6e-52 | 188 |
| LLPS-Phv-0334 | Phaseolus vulgaris | 41.38 | 1e-61 | 213 |
| LLPS-Cus-1635 | Cucumis sativus | 41.38 | 2e-60 | 209 |
| LLPS-Hea-2172 | Helianthus annuus | 41.38 | 1e-61 | 213 |
| LLPS-Dac-1661 | Daucus carota | 41.07 | 2e-56 | 199 |
| LLPS-Sob-2348 | Sorghum bicolor | 40.99 | 1e-61 | 213 |
| LLPS-Coc-0569 | Corchorus capsularis | 40.75 | 1e-60 | 210 |
| LLPS-Pot-0779 | Populus trichocarpa | 40.75 | 1e-61 | 213 |
| LLPS-Zem-2564 | Zea mays | 40.68 | 3e-61 | 212 |
| LLPS-Glm-2224 | Glycine max | 40.44 | 2e-61 | 212 |
| LLPS-Met-0753 | Medicago truncatula | 40.31 | 2e-59 | 207 |
| LLPS-Lep-1560 | Leersia perrieri | 38.75 | 7e-43 | 162 |
| LLPS-Via-2173 | Vigna angularis | 38.75 | 3e-54 | 193 |
| LLPS-Viv-0424 | Vitis vinifera | 38.36 | 3e-53 | 190 |
| LLPS-Vir-1847 | Vigna radiata | 38.34 | 1e-42 | 162 |
| LLPS-Orp-0662 | Oryza punctata | 38.06 | 5e-46 | 171 |
| LLPS-Ors-1389 | Oryza sativa | 37.98 | 2e-46 | 172 |
| LLPS-Orb-0828 | Oryza barthii | 37.63 | 3e-46 | 171 |
| LLPS-Osl-0871 | Ostreococcus lucimarinus | 37.01 | 3e-33 | 132 |
| LLPS-Orm-0204 | Oryza meridionalis | 36.23 | 2e-17 | 83.6 |
| LLPS-Orr-1436 | Oryza rufipogon | 35.4 | 1e-36 | 144 |
| LLPS-Orgl-2291 | Oryza glumaepatula | 35.4 | 1e-36 | 145 |
| LLPS-Orni-2338 | Oryza nivara | 35.4 | 2e-36 | 144 |
| LLPS-Org-2208 | Oryza glaberrima | 35.05 | 7e-36 | 142 |
| LLPS-Chc-0872 | Chondrus crispus | 33.72 | 1e-41 | 159 |
| LLPS-Chr-1693 | Chlamydomonas reinhardtii | 30.5 | 4e-09 | 63.2 |
| LLPS-Sot-1456 | Solanum tuberosum | 28.3 | 4e-06 | 53.1 |
| LLPS-Sol-1512 | Solanum lycopersicum | 27.63 | 4e-06 | 53.1 |
| LLPS-Brr-0208 | Brassica rapa | 27.38 | 3e-08 | 60.1 |