• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aon-2549
HTRA2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: HTRA2
Ensembl Gene: ENSANAG00000028173.1
Ensembl Protein: ENSANAP00000020776.1
Organism: Aotus nancymaae
Taxa ID: 37293
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPRGPLGSLT  TRVPRRPQFP  AFAGWGGGGL  PESWFRRALL  EDFKYQRALR  PTVRLLASWV  60
61    PPLSRAGEEA  AEAELMAALR  AGRGAGWILR  AWRALGGTRW  GKRPLLTPDL  RALLTSGTSD  120
121   PRARVTYGTP  SLRARLSVGV  PEPRVRLTSG  TSDPREQLTE  GTPDTRTQEA  SGNSGSRSRA  180
181   WLAVALGAGG  AVLLLLWGRG  RGPPAVLAEV  PGPPPTSPRS  QYNFIADVVE  KTAPAVVYIE  240
241   ILDRHPFSGR  EIPISNGSGF  VVAADGLIVT  NAHVVADRRK  VRVRLLSGDT  YEAIVTAVDP  300
301   VADIATLRIQ  TKDPLPTLPL  GCSSEVRQGE  FVVAMGSPFA  LQNTITSGIV  SSAQRPARDL  360
361   GLPQTNVEYI  QTDAAIDFGN  SGGPLVNLDG  EVIGVNTMKV  TAGISFAIPS  DRLREFLRRG  420
421   EQENSSCGIN  GSRHCYIGVM  MLTLTPSILA  ELQLRDPRFP  DVRYGVLIHK  VILGSPAHRA  480
481   GLRPGDVILA  IGDKVARSAE  DIYEAVRTQP  KMALRIRRGR  ETLTLYVTPE  ITE  533
Nucleotide CDS Sequence (FASTA)
1     ATGCCCCGCG  GCCCCTTGGG  CAGTCTCACA  ACTCGGGTCC  CGCGGAGACC  ACAATTCCCG  60
61    GCATTCGCGG  GATGGGGAGG  AGGCGGCCTC  CCGGAATCCT  GGTTCCGGCG  TGCACTTCTG  120
121   GAGGACTTCA  AGTACCAGCG  TGCCCTGCGT  CCTACTGTCC  GCTTGCTCGC  GTCCTGGGTG  180
181   CCGCCTCTGA  GTAGGGCGGG  CGAGGAGGCA  GCCGAGGCGG  AGCTGATGGC  TGCGCTGAGG  240
241   GCGGGGCGGG  GTGCAGGCTG  GATCCTCCGG  GCATGGCGGG  CTTTGGGGGG  TACTCGCTGG  300
301   GGGAAGAGAC  CCCTGTTGAC  CCCTGACCTC  CGGGCTCTGC  TGACGTCAGG  AACTTCTGAC  360
361   CCCCGGGCCC  GAGTGACTTA  TGGGACCCCC  AGTCTCCGGG  CCCGGTTGTC  TGTTGGGGTC  420
421   CCTGAACCCC  GAGTACGTCT  GACGTCTGGG  ACCTCGGATC  CCCGGGAACA  ACTGACTGAG  480
481   GGGACCCCAG  ATACAAGGAC  CCAGGAGGCC  TCTGGGAACT  CTGGAAGCCG  TTCGCGCGCG  540
541   TGGCTGGCGG  TGGCGCTGGG  CGCCGGGGGG  GCAGTGCTGT  TGTTGTTGTG  GGGCAGGGGT  600
601   CGGGGTCCTC  CGGCCGTCCT  CGCCGAAGTC  CCTGGCCCGC  CTCCCACCTC  TCCCCGGAGT  660
661   CAGTACAACT  TCATCGCAGA  TGTGGTGGAG  AAGACAGCAC  CTGCCGTTGT  CTATATCGAG  720
721   ATCCTGGATC  GGCACCCTTT  CTCGGGCCGC  GAAATCCCTA  TCTCGAACGG  CTCAGGTTTC  780
781   GTGGTGGCTG  CTGATGGGCT  CATTGTCACC  AACGCCCATG  TGGTGGCTGA  TCGGCGCAAA  840
841   GTCCGTGTGA  GACTGCTTAG  CGGCGACACA  TATGAGGCCA  TCGTCACAGC  TGTGGATCCC  900
901   GTGGCAGACA  TCGCAACGCT  GAGGATTCAG  ACTAAGGATC  CTCTCCCCAC  GTTGCCTCTT  960
961   GGATGCTCAT  CTGAGGTCCG  GCAAGGGGAG  TTTGTTGTTG  CCATGGGAAG  TCCCTTTGCA  1020
1021  CTGCAGAACA  CGATCACATC  CGGCATTGTT  AGCTCTGCTC  AGCGTCCAGC  CAGAGACCTG  1080
1081  GGACTCCCCC  AAACCAATGT  GGAATACATT  CAGACTGATG  CAGCTATTGA  TTTTGGAAAC  1140
1141  TCTGGAGGTC  CCCTGGTTAA  CCTGGATGGA  GAAGTGATTG  GAGTGAACAC  CATGAAGGTC  1200
1201  ACAGCTGGAA  TCTCCTTTGC  TATCCCTTCT  GATCGTCTTC  GAGAATTTCT  GCGTCGTGGG  1260
1261  GAACAGGAAA  ATTCCTCGTG  TGGAATCAAT  GGGTCCCGAC  ACTGCTACAT  TGGGGTGATG  1320
1321  ATGCTGACCC  TGACTCCCAG  CATCCTTGCT  GAACTACAGC  TTCGAGATCC  AAGGTTTCCC  1380
1381  GATGTTCGGT  ATGGTGTACT  CATCCATAAA  GTCATCCTGG  GCTCCCCTGC  ACACCGGGCT  1440
1441  GGCCTGCGGC  CTGGTGATGT  GATTTTGGCC  ATTGGGGACA  AGGTGGCACG  TAGTGCTGAA  1500
1501  GATATTTATG  AAGCTGTTAG  AACCCAACCC  AAGATGGCAT  TGCGGATCCG  GCGGGGACGA  1560
1561  GAAACACTGA  CTTTATATGT  GACCCCTGAG  ATCACAGAAT  GA  1602

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caj-0778Callithrix jacchus98.630.0 796
LLPS-Mam-0194Macaca mulatta88.150.0 684
LLPS-Paa-0835Papio anubis88.150.0 683
LLPS-Cea-4113Cercocebus atys88.150.0 685
LLPS-Maf-4452Macaca fascicularis88.150.0 684
LLPS-Man-1869Macaca nemestrina87.930.0 681
LLPS-Pat-4341Pan troglodytes87.930.0 685
LLPS-Chs-4120Chlorocebus sabaeus87.930.0 682
LLPS-Poa-0459Pongo abelii87.70.0 679
LLPS-Aim-2959Ailuropoda melanoleuca86.790.0 665
LLPS-Mup-1850Mustela putorius furo86.490.0 751
LLPS-Orc-1396Oryctolagus cuniculus86.330.0 669
LLPS-Ict-1637Ictidomys tridecemlineatus86.10.0 666
LLPS-Myl-2506Myotis lucifugus85.190.0 642
LLPS-Sus-3159Sus scrofa84.740.0 641
LLPS-Loa-4232Loxodonta africana83.140.0 663
LLPS-Dar-1227Danio rerio68.444e-153 452
LLPS-Icp-1288Ictalurus punctatus68.033e-148 440
LLPS-Scm-1970Scophthalmus maximus67.52e-149 443
LLPS-Orl-0379Oryzias latipes67.52e-151 448
LLPS-Gaa-1142Gasterosteus aculeatus66.888e-151 442
LLPS-Scf-1516Scleropages formosus66.162e-150 444
LLPS-Pof-1234Poecilia formosa65.315e-143 427
LLPS-Asm-3041Astyanax mexicanus65.02e-146 436
LLPS-Orn-3530Oreochromis niloticus64.982e-148 436
LLPS-Xim-2820Xiphophorus maculatus64.699e-143 426
LLPS-Anc-2210Anolis carolinensis54.433e-109 341
LLPS-Dio-3744Dipodomys ordii53.52e-104 329
LLPS-Lac-2940Latimeria chalumnae53.485e-108 337
LLPS-Ere-0682Erinaceus europaeus53.358e-111 342
LLPS-Cas-2415Carlito syrichta53.164e-109 338
LLPS-Bot-3984Bos taurus53.163e-107 337
LLPS-Ova-4224Ovis aries53.164e-111 340
LLPS-Eqc-1188Equus caballus52.858e-106 334
LLPS-Nol-2246Nomascus leucogenys52.856e-107 335
LLPS-Fec-1631Felis catus52.851e-106 335
LLPS-Urm-3157Ursus maritimus52.854e-108 335
LLPS-Pap-3662Pan paniscus52.853e-106 333
LLPS-Hos-4345Homo sapiens52.852e-106 334
LLPS-Rhb-0233Rhinopithecus bieti52.856e-107 334
LLPS-Tut-0244Tursiops truncatus52.853e-110 338
LLPS-Mal-4372Mandrillus leucophaeus52.855e-108 335
LLPS-Fud-2564Fukomys damarensis52.857e-109 337
LLPS-Gog-3666Gorilla gorilla52.852e-106 334
LLPS-Ten-3752Tetraodon nigroviridis52.531e-103 327
LLPS-Caf-2677Canis familiaris52.532e-107 334
LLPS-Meg-2452Meleagris gallopavo52.531e-109 337
LLPS-Otg-1039Otolemur garnettii52.539e-107 335
LLPS-Ran-3533Rattus norvegicus52.531e-106 334
LLPS-Leo-3756Lepisosteus oculatus52.532e-107 336
LLPS-Mea-0588Mesocricetus auratus52.532e-106 333
LLPS-Mum-4803Mus musculus52.532e-106 334
LLPS-Gaga-3711Gallus gallus52.321e-112 349
LLPS-Anp-1913Anas platyrhynchos52.222e-108 334
LLPS-Fia-2910Ficedula albicollis52.222e-109 338
LLPS-Tar-2039Takifugu rubripes52.043e-105 331
LLPS-Tag-1592Taeniopygia guttata51.93e-107 335
LLPS-Pes-0040Pelodiscus sinensis51.581e-107 332
LLPS-Sah-4018Sarcophilus harrisii51.277e-101 319
LLPS-Xet-2904Xenopus tropicalis51.11e-106 334
LLPS-Mod-0576Monodelphis domestica50.931e-109 342
LLPS-Cap-1026Cavia porcellus50.482e-100 314
LLPS-Ora-2961Ornithorhynchus anatinus50.232e-65 218
LLPS-Drm-2089Drosophila melanogaster49.552e-94 301
LLPS-Cis-1974Ciona savignyi47.02e-87 282
LLPS-Cii-1496Ciona intestinalis46.714e-86 276
LLPS-Ori-2145Oryza indica44.483e-62 217
LLPS-Prp-1026Prunus persica44.415e-65 223
LLPS-Nia-0645Nicotiana attenuata44.02e-60 212
LLPS-Orbr-1508Oryza brachyantha43.797e-63 218
LLPS-Tru-1528Triticum urartu43.468e-57 201
LLPS-Sob-2348Sorghum bicolor43.34e-66 227
LLPS-Sei-0101Setaria italica43.32e-66 228
LLPS-Gas-0249Galdieria sulphuraria43.162e-60 218
LLPS-Tra-2570Triticum aestivum43.19e-59 207
LLPS-Hov-1233Hordeum vulgare43.13e-60 210
LLPS-Arl-0636Arabidopsis lyrata43.082e-66 228
LLPS-Zem-2564Zea mays42.991e-65 225
LLPS-Amt-2078Amborella trichopoda42.998e-62 217
LLPS-Brd-0616Brachypodium distachyon42.952e-62 217
LLPS-Mua-0105Musa acuminata42.954e-58 205
LLPS-Cym-0280Cyanidioschyzon merolae42.916e-55 198
LLPS-Php-0632Physcomitrella patens42.724e-62 217
LLPS-Art-0669Arabidopsis thaliana42.631e-67 231
LLPS-Mae-2375Manihot esculenta42.635e-65 224
LLPS-Gor-2654Gossypium raimondii42.218e-61 213
LLPS-Sem-0232Selaginella moellendorffii42.28e-60 207
LLPS-Brn-2354Brassica napus42.121e-65 226
LLPS-Cus-1635Cucumis sativus42.111e-62 217
LLPS-Phv-0334Phaseolus vulgaris41.886e-62 216
LLPS-Bro-2953Brassica oleracea41.828e-67 229
LLPS-Thc-1153Theobroma cacao41.432e-62 217
LLPS-Coc-0569Corchorus capsularis41.079e-63 218
LLPS-Pot-0779Populus trichocarpa40.794e-65 224
LLPS-Hea-2172Helianthus annuus40.791e-63 219
LLPS-Dac-1661Daucus carota40.752e-56 201
LLPS-Glm-2224Glycine max40.444e-61 213
LLPS-Lep-1560Leersia perrieri39.791e-44 169
LLPS-Ors-1389Oryza sativa39.582e-48 179
LLPS-Met-0753Medicago truncatula39.182e-60 211
LLPS-Orp-0662Oryza punctata39.16e-48 177
LLPS-Orb-0828Oryza barthii39.024e-48 178
LLPS-Viv-0424Vitis vinifera38.992e-57 203
LLPS-Via-2173Vigna angularis38.512e-55 197
LLPS-Osl-0871Ostreococcus lucimarinus37.885e-37 143
LLPS-Vir-1847Vigna radiata36.869e-46 172
LLPS-Orr-1436Oryza rufipogon36.432e-38 151
LLPS-Org-2208Oryza glaberrima36.438e-38 149
LLPS-Orgl-2291Oryza glumaepatula36.432e-38 151
LLPS-Orni-2338Oryza nivara36.433e-38 151
LLPS-Orm-0204Oryza meridionalis36.236e-1474.3
LLPS-Chc-0872Chondrus crispus33.829e-47 174
LLPS-Chr-1693Chlamydomonas reinhardtii29.395e-0963.2
LLPS-Sot-1456Solanum tuberosum27.224e-0653.9
LLPS-Sol-1512Solanum lycopersicum26.693e-0654.3