DrLLPS - Data resource of LLPS

LLPS-Mal-0322
ATM

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Serine-protein kinase ATM
Gene Name:	ATM
Ensembl Gene:	ENSMLEG00000035852.1
Ensembl Protein:	ENSMLEP00000023775.1
Organism:	Mandrillus leucophaeus
Taxa ID:	9568
LLPS Type:	Others

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
DNA damage foci, Nucleolus, Centrosome/Spindle pole body	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Mus musculus	LLPS-Mum-0950	Q62388	Client	Nucleolus	80.36	0.0	4918
Homo sapiens	LLPS-Hos-0566	Q13315	Client	DNA damage foci, Nucleolus, Centrosome/Spindle pole body	94.48	0.0	5780

▼ FUNCTION

Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Plays a role in replication-dependent histone mRNA degradation. Binds DNA ends. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSMLET00000047295.1	ENSMLEP00000023775.1
Ensembl	ENSMLET00000047281.1	ENSMLEP00000023761.1
UniProt		A0A2K5Z7G4, A0A2K5Z7G4_MANLE

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSLALNDLLI CCRQLEHDRA TERKKEVEKF KRLIRDPETI IHLDRHSDSK QGKYLNWDAV 60 61 FRFLQKYIHK ETECLRIAKP NVSASTQASR QKKMQEISSL VKYFIKCANR RAPRLKCQEL 120 121 LNYIMDTVKD SSSGAVYGAD YSNILLKDIL SVRKYWCEIS QQQWLELFSV YFGLYLKPSQ 180 181 DVHRVLVARI IHAVTKGCCS QTDGLNSKFL DFFSKAIQCA RQEKSSPGLN HILAALTIFL 240 241 KTLAVNFRIR VCELGDEILP TLLYIWTQHR LNDSLKEVII ELFQLQIYIH HPKGAKTREK 300 301 GAYESTKWKS ILYNLYDLLV NEISHIGSRG KYSSGFRNIA VKENLIELMA DICHQVQKKI 360 361 ELGWEVIKDH LQKSQNDFDL VPWLQIATQL ISKYPASLPN CELSPLLMIL SQLLPQQRHG 420 421 ERTPYVLRCL TEVALCQDKR SNLESSQKSD LLKLWNKIWC ITFRGISSEQ IQAENFGLLG 480 481 AIIQSSLVEV DREFWKLFTG SACRPSCPAV CCLTLALTTS LVPGTVKMGI EQNMCEVNRS 540 541 FSLKESIMKW LLFYQLEGDL ENSTEVPPIL HSNFPHLVLE KILVSLTMKN CKAAMNFFQS 600 601 VPECEHHRKD KEELSFSEVE ELFLQTTFDK MDFLTIVREC GIEKHQSSIG FSVHQNLKES 660 661 LDCYLLGLSE QLLNNYSSES LMQCAGESIT LFKNKTNEEF RIGSLRNMMH LFTRCLSNCT 720 721 KKSPNKIASG FFLRLLTSKL MNDIADICKS FASLIKKPFD RGEVESMEED TNGNLMEVED 780 781 QSSMNLFNDY PDSSVSDANE PGESQSTIGA INPLAEEYLS KQDLLFLDML KFLCLCVTTA 840 841 QTNTVSFRAA DIRRKLLMLI DSSTLDPTKS LHLHMYLMLL KELPGEEYPL PMEDVVELLK 900 901 PLSNVCSLYR RDQDVCKTIL NHVLHIVKNL GQSNMDSENT RDAQGQFLTV IGAFWHLTKE 960 961 RKYTFSVRMA LVNCLKTLLE ADPYSKWAIL NVMGKDFPVN EVFTQFLADN HHRVRMLAAE 1020 1021 SINRLFQDTK GDSSTLLKAL PLRLQQTAFE NAYLKAQEGM REMSHSAENP EPLDEIYNRK 1080 1081 SVLLMLIAVV LSCSPICEKQ ALFALCKSVK ENGLEPHLVK KVLEKVSETF GYRCLEDFMA 1140 1141 SHLDYLVLEW LNLQDTEYNL SSFPFILLNY TNIEDFYRSC YKVLVPHLVI RSHFDEVKSI 1200 1201 ANQIQQDWKS LLTDCFPKIL VNILPYFAYE GTGDSGMAQQ RETATKVYDM LKSENLLGKQ 1260 1261 IDHLFISNLP EIVVELLMTL HEPANSSASQ STDLCDFSGL VLNSWPQVIP PCWPIKVLGL 1320 1321 QDSYQKILLA ICEQAAETNN VYKKHRILKI YHLFVSLLLK DIKSGLGGAW AFVLRDVIYT 1380 1381 LIHYINQRPS RIMDVSLRSF SLCCDLLSQV CQTAVTYCKD ALENHLHVIV GTLIPLVDEQ 1440 1441 VEVQKQVLDL LKYLVIDNKD NENLYLTIKL LDPFPDHVVF KDLRIAQQKI KYSRGPFSLL 1500 1501 EEINHFLSVS VYDALPLTRL EGLKDLRRQL ELHKDQMMDI MRASQDNPQD GIMVKLVVNL 1560 1561 LQLSKMAINH TGEKEVLEAV GSCLGEVGPI DFSTIAIQHS KDASYTKALK LFEGKELQWT 1620 1621 FIMLTYLNNT LVEDCVKVRS AAVTCLKNIL ATKTGHSFWE IYKMTTDPML AYLQPFRTSR 1680 1681 KKFLEVPRFD KENPFEGLDD INLWIPLSEN HDIWIKTLTC AFLDSGGTKC EILQLLKPMC 1740 1741 EVKTDFCQTV LPYLIHDILL QDTNESWRNL LSTHVQGFFT SCLRHFSQTS RSTTPANLDS 1800 1801 ESEHFFRCCL DKKSQRTMLG VVDYMRRQKR PSSGTIFDDA FWLDLNYLEV AKVAQSCAAH 1860 1861 FTALLYAEIY ADKKSMDDQE KRSLAFEEGS QSTTISSLSE KSKEETGISL QDLLLEIYRS 1920 1921 IGEPDSLYGC GGGKMLQPIT RLRTYEHEAM WGKALVTYDL ETAISSSTRQ AGIIQALQNL 1980 1981 GLCHILSVYL KGLDYENKDW CPELQELHYQ AAWRNMQWDH CTYVSKEIEG TSYHESLYNA 2040 2041 LQSLRDREFS TFYESLKYAR VKEVEELCKR SLESVYSLYP TLSRLQAIGE LESIGELFSK 2100 2101 SVTHRQLSEV YIKWQKHSQL LKDSDFSFQE PIMALRTVIL EILMEKEIDN SQRECIKEIL 2160 2161 TKHLVELSIL ARTFKNTQLP ERAIFQIKQY NSVSCGVSEW QLEEAQVFWA KKEQSLALSI 2220 2221 LKQMIKKLDA SCAANNPSLK LIYTECLRVC GNWLAETCLE NPAVIMQTYL EKAVEVAGNY 2280 2281 DGESNDELRN GKMKAFLSLA RFSDTQYQRI ENYMKSSEFE NKQALLKRAK EEVGLLREHK 2340 2341 IQTNRYTVKV QRELELDELA LRALKEDRKR FLCKAVENYV NCLLSGEEHD MWVFRLCSLW 2400 2401 LENSGVSEVN GMMKRDGMKI PSYKFLPLMY QLAARMGTKM MGGLGFHEVL NNLISRISMD 2460 2461 HPHHTLFIIL ALANANRDEF LTKPEVARRS RITKNAPKQS SQLDEDRTEA ANRIICTIRS 2520 2521 RRPQMVRSVE ALCDAYIILA NLDATQWKTQ RKGINIPADQ PITKLKNLED VVVPTMEIKV 2580 2581 DHTGEYGNLV TIQSFKAEFR LAGGVNLPKI IDCVGSDGKE RRQLVKGRDD LRQDAVMQQV 2640 2641 FQMCNTLLQR NTETRKRKLT ICTYKVVPLS QRSGVLEWCT GTIPIGEFLV NNEDGAHKRY 2700 2701 RPNDFSAFQC QKKMMEVQKK SFEDKYEVFM DVCQNFQPVF RYFCMEKFLD PAIWFEKRLA 2760 2761 YTRSVATSSI VGYILGLGDR HVQNILINEQ SAELVHIDLG VAFEQGKILP TPETVPFRLT 2820 2821 RDIVDGMGIT GVEGVFRRCC EKTMEVMRNS QETLLTIVEV LLYDPLFDWT MNPLKALYLQ 2880 2881 QRPEDETELH PTLNADDQEC KRNLSDIDQS FNKVAERVLM RLQEKLKGVE EGTVLSVGGQ 2940 2941 VNLLIQQAMD PKNLSRLFPG WKAWV 2965
Nucleotide CDS Sequence (FASTA)
1 ATGAGTCTAG CACTTAATGA TCTGCTTATT TGCTGCCGTC AACTAGAACA TGATAGAGCT 60 61 ACAGAACGAA AGAAAGAAGT TGAGAAATTT AAGCGCCTGA TTCGAGATCC TGAAACAATT 120 121 ATACATCTAG ATCGGCATTC AGATTCCAAA CAAGGAAAAT ATTTGAATTG GGATGCTGTT 180 181 TTTAGATTTT TACAGAAATA TATTCATAAA GAAACAGAAT GTCTGAGAAT AGCAAAACCA 240 241 AATGTATCAG CCTCAACACA AGCCTCCAGG CAGAAAAAGA TGCAGGAAAT CAGTAGTTTG 300 301 GTCAAATACT TCATCAAATG TGCAAACAGA AGAGCACCTA GGCTAAAATG TCAAGAACTC 360 361 TTGAATTATA TCATGGATAC AGTGAAAGAT TCATCTAGTG GTGCTGTTTA CGGAGCTGAT 420 421 TATAGCAACA TACTACTCAA AGATATTCTT TCTGTGAGAA AATACTGGTG TGAAATATCT 480 481 CAGCAACAGT GGTTAGAATT GTTCTCTGTG TACTTCGGGC TTTATCTGAA ACCTTCACAA 540 541 GATGTTCATA GAGTTTTAGT GGCTAGAATA ATTCATGCTG TTACCAAAGG ATGCTGTTCT 600 601 CAGACTGATG GATTAAATTC CAAATTTTTG GACTTTTTTT CCAAGGCTAT TCAGTGTGCA 660 661 AGACAAGAAA AGAGCTCTCC AGGTCTAAAT CATATCTTAG CAGCTCTTAC TATCTTCCTC 720 721 AAGACTTTGG CTGTCAACTT TCGAATTCGA GTGTGTGAAT TAGGAGATGA AATTCTTCCC 780 781 ACTTTGCTTT ATATTTGGAC TCAACATAGA CTTAATGATT CTTTAAAAGA AGTCATTATT 840 841 GAGTTATTTC AACTGCAAAT TTATATCCAT CATCCAAAAG GAGCCAAAAC CCGAGAAAAA 900 901 GGTGCTTATG AATCAACAAA ATGGAAAAGT ATTTTATACA ACTTATATGA TCTGCTAGTG 960 961 AATGAGATAA GTCATATAGG AAGTAGAGGA AAGTATTCTT CAGGATTTCG TAATATTGCC 1020 1021 GTCAAAGAAA ATTTGATTGA ATTGATGGCA GATATTTGTC ACCAGGTACA GAAGAAAATA 1080 1081 GAACTAGGCT GGGAAGTAAT AAAAGATCAC CTTCAGAAGT CACAGAATGA TTTCGATCTT 1140 1141 GTGCCTTGGC TACAGATTGC AACCCAATTA ATATCAAAGT ATCCTGCAAG TTTACCTAAC 1200 1201 TGTGAGCTGT CTCCGTTACT GATGATACTC TCTCAGCTTC TACCCCAACA GCGACATGGG 1260 1261 GAACGTACAC CGTATGTGTT ACGATGCCTT ACGGAAGTTG CACTGTGTCA AGACAAGAGG 1320 1321 TCAAACCTAG AAAGCTCACA AAAGTCAGAT TTATTAAAAC TCTGGAATAA AATTTGGTGT 1380 1381 ATTACCTTTC GTGGTATAAG TTCTGAGCAA ATACAAGCTG AAAACTTTGG CTTACTTGGA 1440 1441 GCCATAATTC AGAGTAGTTT AGTTGAGGTT GACAGAGAAT TCTGGAAGTT ATTTACTGGG 1500 1501 TCAGCCTGCA GACCTTCATG TCCTGCAGTA TGCTGTTTGA CTTTGGCACT GACCACCAGT 1560 1561 TTAGTTCCTG GAACAGTAAA AATGGGAATA GAGCAAAATA TGTGTGAAGT AAATAGAAGC 1620 1621 TTTTCTTTAA AGGAATCAAT AATGAAATGG CTCTTATTCT ATCAGCTAGA GGGTGACTTA 1680 1681 GAAAATAGTA CAGAAGTGCC TCCAATTCTT CACAGTAATT TTCCTCATCT TGTACTGGAG 1740 1741 AAAATTCTTG TGAGTCTCAC TATGAAAAAC TGTAAAGCTG CAATGAATTT TTTCCAAAGT 1800 1801 GTGCCAGAAT GTGAACACCA CCGAAAAGAT AAAGAAGAAC TTTCATTCTC AGAAGTAGAA 1860 1861 GAACTATTTC TTCAGACAAC TTTTGACAAG ATGGACTTTT TAACCATTGT GAGAGAATGT 1920 1921 GGTATAGAAA AGCACCAGTC CAGTATTGGC TTCTCTGTCC ACCAGAATCT CAAGGAATCA 1980 1981 TTGGATTGCT ATCTTCTGGG ATTGTCAGAA CAGCTTCTAA ATAATTACTC ATCTGAGTCT 2040 2041 CTAATGCAGT GTGCAGGAGA AAGTATCACT CTGTTTAAAA ATAAGACAAA TGAGGAATTC 2100 2101 AGAATTGGTT CCTTGAGAAA TATGATGCAT TTATTTACAC GTTGCTTGAG CAACTGTACC 2160 2161 AAGAAGAGTC CAAATAAGAT TGCATCTGGC TTTTTCCTGC GATTGTTAAC ATCAAAGCTA 2220 2221 ATGAATGACA TTGCAGATAT TTGTAAAAGT TTCGCATCCT TAATCAAAAA GCCATTTGAC 2280 2281 CGTGGAGAAG TAGAATCAAT GGAAGAGGAT ACTAATGGAA ATCTAATGGA GGTGGAGGAT 2340 2341 CAGTCATCCA TGAATCTATT TAACGATTAC CCTGATAGTA GTGTTAGTGA TGCAAATGAA 2400 2401 CCTGGAGAGA GCCAAAGTAC CATAGGTGCC ATTAATCCTT TAGCTGAAGA ATATCTGTCA 2460 2461 AAGCAAGATC TACTCTTCTT AGACATGCTC AAGTTCTTGT GTTTGTGTGT AACTACTGCT 2520 2521 CAGACCAATA CTGTGTCCTT TAGGGCAGCT GATATTCGGA GGAAATTGTT AATGTTAATT 2580 2581 GATTCTAGCA CGCTAGACCC TACCAAATCC CTCCACCTGC ATATGTATCT AATGCTTTTA 2640 2641 AAGGAGCTTC CTGGAGAAGA GTACCCCTTG CCAATGGAAG ATGTTGTTGA ACTTCTGAAA 2700 2701 CCACTATCCA ATGTGTGTTC TTTGTATCGT CGTGACCAAG ATGTTTGTAA AACTATTTTA 2760 2761 AACCATGTCC TTCATATAGT GAAAAACCTA GGTCAAAGCA ATATGGACTC TGAGAATACA 2820 2821 AGGGATGCTC AAGGACAGTT TCTTACAGTA ATTGGAGCAT TTTGGCATCT AACAAAGGAG 2880 2881 AGGAAATATA CATTCTCTGT AAGAATGGCC CTAGTAAACT GCCTTAAAAC TTTGCTTGAG 2940 2941 GCCGATCCTT ATTCAAAATG GGCCATTCTT AATGTAATGG GAAAAGACTT TCCTGTAAAC 3000 3001 GAAGTATTTA CACAATTTCT TGCTGATAAT CATCACCGAG TTCGAATGTT GGCTGCAGAG 3060 3061 TCAATCAATA GATTGTTCCA GGACACGAAG GGAGATTCTT CCACATTACT GAAAGCACTT 3120 3121 CCTTTGAGGC TTCAGCAAAC AGCTTTTGAA AATGCATACC TGAAAGCTCA GGAAGGAATG 3180 3181 AGAGAAATGT CCCATAGTGC TGAGAACCCT GAACCTTTGG ATGAAATTTA TAATAGAAAA 3240 3241 TCTGTTTTAC TGATGTTGAT AGCTGTGGTT TTATCCTGTA GCCCTATCTG TGAAAAACAG 3300 3301 GCTTTGTTTG CCCTATGTAA ATCTGTGAAG GAGAATGGAT TAGAACCTCA CCTTGTGAAA 3360 3361 AAGGTTTTAG AGAAAGTTTC TGAAACTTTT GGATATAGAT GTTTAGAAGA CTTTATGGCA 3420 3421 TCTCATTTAG ATTATCTGGT TTTGGAATGG CTAAATCTTC AAGATACTGA ATACAACTTA 3480 3481 TCTTCTTTTC CTTTTATTTT ATTAAACTAT ACAAATATTG AGGATTTCTA TAGATCTTGT 3540 3541 TATAAGGTTT TGGTTCCACA TCTGGTGATT AGAAGTCATT TTGATGAGGT GAAGTCCATT 3600 3601 GCTAATCAGA TTCAACAGGA CTGGAAAAGT CTTCTAACAG ACTGCTTTCC AAAGATTCTT 3660 3661 GTAAATATTC TTCCTTACTT TGCCTATGAG GGTACAGGAG ACAGTGGGAT GGCACAGCAA 3720 3721 AGAGAGACTG CTACCAAGGT CTATGATATG CTTAAAAGTG AAAACTTACT GGGAAAACAG 3780 3781 ATCGATCATT TATTCATTAG TAACTTACCA GAGATTGTGG TGGAGTTATT GATGACGTTA 3840 3841 CATGAGCCAG CAAATTCTAG TGCCAGTCAG AGCACTGACC TCTGTGACTT TTCAGGGCTG 3900 3901 GTCTTGAACT CCTGGCCTCA AGTGATTCCC CCGTGTTGGC CAATCAAAGT CCTGGGATTA 3960 3961 CAGGATTCCT ATCAGAAAAT TCTTCTTGCC ATATGTGAGC AAGCAGCTGA AACAAATAAT 4020 4021 GTTTATAAGA AGCACAGAAT TCTTAAAATA TACCACCTGT TCGTTAGTTT ATTACTGAAA 4080 4081 GATATAAAAA GTGGCTTAGG AGGAGCTTGG GCGTTTGTTC TTCGAGATGT TATTTATACT 4140 4141 TTGATTCACT ATATCAACCA AAGGCCTTCT CGTATCATGG ATGTGTCATT ACGTAGCTTC 4200 4201 TCCCTTTGTT GTGACTTATT AAGTCAGGTT TGCCAGACAG CAGTGACTTA CTGTAAGGAT 4260 4261 GCTCTAGAAA ACCATCTTCA TGTTATTGTT GGTACACTTA TACCCCTTGT GGATGAGCAG 4320 4321 GTGGAAGTTC AGAAACAGGT ATTGGACTTG TTGAAATACT TAGTGATAGA TAACAAGGAT 4380 4381 AATGAAAACC TCTATCTCAC GATTAAGCTT TTAGATCCTT TTCCTGACCA TGTTGTTTTT 4440 4441 AAGGATTTGC GTATTGCTCA GCAAAAAATC AAATACAGTA GAGGACCCTT TTCACTCTTG 4500 4501 GAGGAAATTA ACCATTTTCT CTCAGTAAGT GTTTATGATG CACTTCCATT GACAAGACTT 4560 4561 GAAGGACTAA AGGATCTTCG AAGACAACTG GAACTACATA AAGATCAGAT GATGGACATT 4620 4621 ATGAGAGCAT CTCAGGATAA TCCACAAGAT GGGATTATGG TGAAGCTAGT TGTCAATTTG 4680 4681 TTGCAGTTAT CCAAGATGGC AATAAACCAC ACTGGTGAAA AAGAAGTTCT AGAGGCTGTT 4740 4741 GGAAGCTGCT TGGGAGAAGT GGGTCCTATA GATTTCTCTA CCATAGCTAT ACAACATAGT 4800 4801 AAAGATGCAT CTTATACCAA GGCCCTTAAG TTATTTGAAG GTAAAGAACT TCAGTGGACC 4860 4861 TTCATAATGC TGACCTACCT GAATAACACA CTGGTAGAAG ATTGTGTCAA AGTTCGATCA 4920 4921 GCAGCTGTTA CTTGTTTGAA AAACATTTTA GCCACAAAGA CTGGACATAG TTTCTGGGAG 4980 4981 ATTTATAAGA TGACAACAGA TCCAATGCTG GCCTATCTAC AGCCTTTTAG AACATCGAGA 5040 5041 AAAAAGTTTT TAGAAGTACC CAGATTTGAC AAAGAAAACC CTTTTGAAGG CCTGGATGAT 5100 5101 ATAAATCTGT GGATTCCTCT GAGTGAAAAT CATGACATTT GGATAAAGAC ACTGACTTGT 5160 5161 GCTTTTTTGG ACAGTGGAGG CACAAAATGT GAAATTCTTC AATTATTAAA GCCAATGTGT 5220 5221 GAAGTGAAAA CTGACTTTTG TCAGACTGTA CTTCCATACT TGATTCATGA TATTTTGCTC 5280 5281 CAAGATACAA ATGAATCATG GAGAAATCTG CTTTCTACAC ATGTTCAGGG ATTTTTCACC 5340 5341 AGCTGTCTTC GACACTTCTC ACAAACGAGC CGATCCACAA CCCCTGCAAA CTTGGATTCA 5400 5401 GAGTCAGAGC ACTTTTTCCG ATGCTGTTTG GATAAAAAAT CACAAAGAAC AATGCTTGGT 5460 5461 GTTGTGGACT ACATGAGAAG ACAAAAGAGA CCTTCTTCAG GAACAATTTT TGATGATGCT 5520 5521 TTCTGGCTGG ATTTAAATTA TCTAGAAGTT GCCAAGGTAG CTCAGTCTTG TGCTGCTCAC 5580 5581 TTTACAGCTT TACTCTATGC AGAAATCTAT GCAGATAAGA AAAGCATGGA TGATCAAGAG 5640 5641 AAAAGAAGTC TTGCATTTGA AGAAGGAAGC CAAAGTACAA CTATTTCTAG CTTGAGTGAA 5700 5701 AAAAGTAAAG AAGAAACTGG AATAAGTTTA CAGGATCTTC TCTTAGAAAT CTACAGAAGT 5760 5761 ATAGGAGAGC CAGATAGTTT GTATGGCTGT GGTGGAGGGA AGATGTTACA ACCCATTACT 5820 5821 AGACTACGAA CATATGAACA CGAAGCAATG TGGGGCAAAG CCCTAGTAAC ATATGACCTT 5880 5881 GAAACAGCAA TCTCCTCATC AACCCGCCAG GCAGGAATCA TTCAGGCCTT GCAGAATTTG 5940 5941 GGACTCTGCC ATATTCTTTC TGTGTATTTG AAAGGATTAG ATTATGAAAA TAAAGACTGG 6000 6001 TGTCCTGAAC TACAGGAACT TCATTACCAA GCAGCATGGA GGAATATGCA GTGGGACCAT 6060 6061 TGCACTTATG TCAGCAAAGA AATAGAAGGA ACCAGTTACC ATGAATCATT GTACAATGCT 6120 6121 CTACAATCTC TAAGAGACAG AGAATTCTCT ACATTTTATG AAAGTCTCAA ATATGCAAGA 6180 6181 GTAAAAGAAG TGGAAGAGTT GTGTAAGCGC AGCCTTGAGT CTGTGTATTC GCTCTACCCC 6240 6241 ACACTCAGCA GGTTGCAGGC CATTGGAGAG CTGGAAAGCA TTGGGGAGCT TTTCTCAAAA 6300 6301 TCAGTCACAC ATAGACAACT CTCTGAAGTA TATATTAAGT GGCAGAAACA CTCCCAGCTT 6360 6361 CTCAAGGACA GTGATTTTAG TTTTCAGGAG CCTATCATGG CTCTACGCAC AGTCATTTTG 6420 6421 GAGATCCTGA TGGAAAAGGA AATAGACAAC TCACAAAGAG AGTGTATTAA GGAGATTCTC 6480 6481 ACCAAACACC TTGTAGAACT CTCTATACTG GCCAGAACTT TCAAGAACAC TCAGCTCCCT 6540 6541 GAAAGGGCAA TATTTCAAAT TAAACAGTAT AATTCAGTTA GCTGTGGAGT CTCTGAGTGG 6600 6601 CAGCTGGAAG AAGCACAAGT ATTCTGGGCA AAAAAGGAGC AGAGTCTTGC CCTGAGTATT 6660 6661 CTCAAGCAAA TGATCAAGAA GTTGGATGCC AGCTGTGCAG CGAACAATCC CAGCCTAAAA 6720 6721 CTTATATACA CAGAATGTCT AAGGGTTTGT GGCAACTGGT TAGCAGAAAC TTGCTTAGAA 6780 6781 AATCCTGCGG TCATCATGCA GACCTATCTA GAAAAGGCAG TAGAAGTTGC TGGCAATTAT 6840 6841 GATGGAGAAA GTAATGATGA GCTAAGAAAT GGAAAAATGA AGGCATTTCT GTCATTAGCC 6900 6901 CGGTTTTCAG ATACTCAGTA CCAAAGAATT GAAAACTACA TGAAATCATC AGAATTTGAA 6960 6961 AACAAGCAAG CTCTCCTGAA AAGAGCCAAA GAGGAAGTAG GTCTCCTTAG GGAACATAAA 7020 7021 ATTCAGACCA ACAGATACAC AGTAAAAGTT CAGCGAGAGC TGGAGTTGGA TGAACTTGCC 7080 7081 CTGCGTGCAT TGAAAGAGGA TCGTAAACGC TTCTTATGTA AAGCAGTTGA AAATTACGTC 7140 7141 AACTGCTTAT TAAGTGGAGA AGAACATGAT ATGTGGGTAT TCCGACTTTG TTCCCTCTGG 7200 7201 CTTGAAAATT CTGGAGTTTC TGAAGTCAAT GGCATGATGA AGAGAGATGG AATGAAGATT 7260 7261 CCATCATATA AATTTTTGCC TCTTATGTAC CAACTGGCTG CTAGAATGGG GACCAAGATG 7320 7321 ATGGGAGGCC TAGGATTTCA TGAAGTCCTC AATAATCTAA TCTCTAGAAT TTCAATGGAT 7380 7381 CACCCCCATC ATACTTTATT TATTATACTG GCCTTAGCAA ATGCAAACAG AGATGAATTT 7440 7441 CTGACTAAAC CAGAGGTAGC AAGAAGAAGT AGAATAACTA AAAATGCGCC TAAACAAAGC 7500 7501 TCTCAGCTTG ATGAGGATCG AACAGAGGCT GCAAACAGAA TAATATGTAC TATCAGAAGT 7560 7561 AGGAGACCTC AGATGGTCAG AAGTGTTGAG GCACTTTGTG ATGCTTATAT TATATTAGCA 7620 7621 AACTTAGATG CCACTCAGTG GAAGACTCAG AGAAAAGGCA TAAATATTCC AGCAGACCAG 7680 7681 CCAATTACTA AACTTAAGAA TTTAGAAGAT GTTGTTGTCC CTACTATGGA AATTAAGGTG 7740 7741 GACCACACAG GAGAATATGG AAATCTCGTG ACTATACAGT CATTTAAAGC AGAATTTCGC 7800 7801 TTAGCAGGAG GTGTAAATTT ACCAAAAATA ATAGATTGTG TAGGTTCTGA TGGCAAGGAG 7860 7861 AGGAGACAGC TTGTTAAGGG CCGTGATGAC CTGAGACAAG ATGCTGTCAT GCAACAGGTC 7920 7921 TTCCAGATGT GTAATACATT ACTGCAGAGA AACACTGAAA CTAGGAAGAG GAAATTAACT 7980 7981 ATCTGTACTT ATAAGGTGGT TCCCCTCTCT CAGCGAAGTG GTGTTCTTGA ATGGTGTACA 8040 8041 GGAACTATCC CTATTGGTGA ATTTCTTGTT AACAATGAAG ATGGTGCTCA TAAAAGATAC 8100 8101 AGGCCAAATG ATTTCAGTGC CTTTCAATGC CAAAAGAAAA TGATGGAGGT GCAAAAAAAG 8160 8161 TCTTTTGAAG ATAAATATGA AGTCTTCATG GATGTTTGCC AAAATTTTCA ACCAGTTTTC 8220 8221 CGTTACTTCT GCATGGAAAA ATTCTTGGAT CCAGCTATTT GGTTTGAGAA GCGATTGGCT 8280 8281 TATACGCGCA GTGTAGCCAC GTCTTCTATT GTTGGTTACA TACTTGGACT TGGTGATAGA 8340 8341 CATGTACAGA ATATCTTGAT AAATGAGCAG TCAGCAGAAC TTGTACATAT AGATTTGGGT 8400 8401 GTTGCTTTTG AACAGGGCAA AATCCTTCCT ACTCCTGAGA CAGTTCCTTT TAGACTCACC 8460 8461 AGAGATATTG TGGATGGCAT GGGCATTACT GGTGTTGAAG GTGTCTTCAG AAGATGCTGT 8520 8521 GAGAAAACCA TGGAAGTGAT GAGAAACTCT CAGGAAACTC TGTTAACCAT TGTAGAGGTC 8580 8581 CTTCTGTATG ATCCACTCTT TGACTGGACC ATGAATCCTT TGAAAGCTTT GTATTTACAG 8640 8641 CAGAGGCCAG AAGATGAAAC TGAGCTTCAC CCTACTCTGA ATGCAGATGA CCAAGAATGC 8700 8701 AAACGAAATC TCAGTGATAT TGACCAGAGT TTCAACAAAG TAGCTGAACG TGTCTTAATG 8760 8761 AGACTACAAG AGAAACTGAA AGGAGTGGAA GAAGGCACTG TGCTCAGTGT TGGTGGACAA 8820 8821 GTGAATCTGC TCATACAGCA GGCCATGGAC CCCAAAAATC TCAGCCGACT TTTCCCCGGA 8880 8881 TGGAAAGCTT GGGTGTGA 8898

Protein Sequence

>LLPS-Mal-0322|ENSMLEG00000035852.1
MSLALNDLLICCRQLEHDRATERKKEVEKFKRLIRDPETIIHLDRHSDSKQGKYLNWDAVFRFLQKYIHKETECLRIAKPNVSASTQASRQKKMQEISSLVKYFIKCANRRAPRLKCQELLNYIMDTVKDSSSGAVYGADYSNILLKDILSVRKYWCEISQQQWLELFSVYFGLYLKPSQDVHRVLVARIIHAVTKGCCSQTDGLNSKFLDFFSKAIQCARQEKSSPGLNHILAALTIFLKTLAVNFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTREKGAYESTKWKSILYNLYDLLVNEISHIGSRGKYSSGFRNIAVKENLIELMADICHQVQKKIELGWEVIKDHLQKSQNDFDLVPWLQIATQLISKYPASLPNCELSPLLMILSQLLPQQRHGERTPYVLRCLTEVALCQDKRSNLESSQKSDLLKLWNKIWCITFRGISSEQIQAENFGLLGAIIQSSLVEVDREFWKLFTGSACRPSCPAVCCLTLALTTSLVPGTVKMGIEQNMCEVNRSFSLKESIMKWLLFYQLEGDLENSTEVPPILHSNFPHLVLEKILVSLTMKNCKAAMNFFQSVPECEHHRKDKEELSFSEVEELFLQTTFDKMDFLTIVRECGIEKHQSSIGFSVHQNLKESLDCYLLGLSEQLLNNYSSESLMQCAGESITLFKNKTNEEFRIGSLRNMMHLFTRCLSNCTKKSPNKIASGFFLRLLTSKLMNDIADICKSFASLIKKPFDRGEVESMEEDTNGNLMEVEDQSSMNLFNDYPDSSVSDANEPGESQSTIGAINPLAEEYLSKQDLLFLDMLKFLCLCVTTAQTNTVSFRAADIRRKLLMLIDSSTLDPTKSLHLHMYLMLLKELPGEEYPLPMEDVVELLKPLSNVCSLYRRDQDVCKTILNHVLHIVKNLGQSNMDSENTRDAQGQFLTVIGAFWHLTKERKYTFSVRMALVNCLKTLLEADPYSKWAILNVMGKDFPVNEVFTQFLADNHHRVRMLAAESINRLFQDTKGDSSTLLKALPLRLQQTAFENAYLKAQEGMREMSHSAENPEPLDEIYNRKSVLLMLIAVVLSCSPICEKQALFALCKSVKENGLEPHLVKKVLEKVSETFGYRCLEDFMASHLDYLVLEWLNLQDTEYNLSSFPFILLNYTNIEDFYRSCYKVLVPHLVIRSHFDEVKSIANQIQQDWKSLLTDCFPKILVNILPYFAYEGTGDSGMAQQRETATKVYDMLKSENLLGKQIDHLFISNLPEIVVELLMTLHEPANSSASQSTDLCDFSGLVLNSWPQVIPPCWPIKVLGLQDSYQKILLAICEQAAETNNVYKKHRILKIYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHYINQRPSRIMDVSLRSFSLCCDLLSQVCQTAVTYCKDALENHLHVIVGTLIPLVDEQVEVQKQVLDLLKYLVIDNKDNENLYLTIKLLDPFPDHVVFKDLRIAQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRLEGLKDLRRQLELHKDQMMDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAVGSCLGEVGPIDFSTIAIQHSKDASYTKALKLFEGKELQWTFIMLTYLNNTLVEDCVKVRSAAVTCLKNILATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRFDKENPFEGLDDINLWIPLSENHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWRNLLSTHVQGFFTSCLRHFSQTSRSTTPANLDSESEHFFRCCLDKKSQRTMLGVVDYMRRQKRPSSGTIFDDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEAMWGKALVTYDLETAISSSTRQAGIIQALQNLGLCHILSVYLKGLDYENKDWCPELQELHYQAAWRNMQWDHCTYVSKEIEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEELCKRSLESVYSLYPTLSRLQAIGELESIGELFSKSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEIDNSQRECIKEILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLIYTECLRVCGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESNDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDELALRALKEDRKRFLCKAVENYVNCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPSYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNAPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYGNLVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTIPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEDKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV

Nucleotide Sequence

>LLPS-Mal-0322|ENSMLEG00000035852.1
ATGAGTCTAGCACTTAATGATCTGCTTATTTGCTGCCGTCAACTAGAACATGATAGAGCTACAGAACGAAAGAAAGAAGTTGAGAAATTTAAGCGCCTGATTCGAGATCCTGAAACAATTATACATCTAGATCGGCATTCAGATTCCAAACAAGGAAAATATTTGAATTGGGATGCTGTTTTTAGATTTTTACAGAAATATATTCATAAAGAAACAGAATGTCTGAGAATAGCAAAACCAAATGTATCAGCCTCAACACAAGCCTCCAGGCAGAAAAAGATGCAGGAAATCAGTAGTTTGGTCAAATACTTCATCAAATGTGCAAACAGAAGAGCACCTAGGCTAAAATGTCAAGAACTCTTGAATTATATCATGGATACAGTGAAAGATTCATCTAGTGGTGCTGTTTACGGAGCTGATTATAGCAACATACTACTCAAAGATATTCTTTCTGTGAGAAAATACTGGTGTGAAATATCTCAGCAACAGTGGTTAGAATTGTTCTCTGTGTACTTCGGGCTTTATCTGAAACCTTCACAAGATGTTCATAGAGTTTTAGTGGCTAGAATAATTCATGCTGTTACCAAAGGATGCTGTTCTCAGACTGATGGATTAAATTCCAAATTTTTGGACTTTTTTTCCAAGGCTATTCAGTGTGCAAGACAAGAAAAGAGCTCTCCAGGTCTAAATCATATCTTAGCAGCTCTTACTATCTTCCTCAAGACTTTGGCTGTCAACTTTCGAATTCGAGTGTGTGAATTAGGAGATGAAATTCTTCCCACTTTGCTTTATATTTGGACTCAACATAGACTTAATGATTCTTTAAAAGAAGTCATTATTGAGTTATTTCAACTGCAAATTTATATCCATCATCCAAAAGGAGCCAAAACCCGAGAAAAAGGTGCTTATGAATCAACAAAATGGAAAAGTATTTTATACAACTTATATGATCTGCTAGTGAATGAGATAAGTCATATAGGAAGTAGAGGAAAGTATTCTTCAGGATTTCGTAATATTGCCGTCAAAGAAAATTTGATTGAATTGATGGCAGATATTTGTCACCAGGTACAGAAGAAAATAGAACTAGGCTGGGAAGTAATAAAAGATCACCTTCAGAAGTCACAGAATGATTTCGATCTTGTGCCTTGGCTACAGATTGCAACCCAATTAATATCAAAGTATCCTGCAAGTTTACCTAACTGTGAGCTGTCTCCGTTACTGATGATACTCTCTCAGCTTCTACCCCAACAGCGACATGGGGAACGTACACCGTATGTGTTACGATGCCTTACGGAAGTTGCACTGTGTCAAGACAAGAGGTCAAACCTAGAAAGCTCACAAAAGTCAGATTTATTAAAACTCTGGAATAAAATTTGGTGTATTACCTTTCGTGGTATAAGTTCTGAGCAAATACAAGCTGAAAACTTTGGCTTACTTGGAGCCATAATTCAGAGTAGTTTAGTTGAGGTTGACAGAGAATTCTGGAAGTTATTTACTGGGTCAGCCTGCAGACCTTCATGTCCTGCAGTATGCTGTTTGACTTTGGCACTGACCACCAGTTTAGTTCCTGGAACAGTAAAAATGGGAATAGAGCAAAATATGTGTGAAGTAAATAGAAGCTTTTCTTTAAAGGAATCAATAATGAAATGGCTCTTATTCTATCAGCTAGAGGGTGACTTAGAAAATAGTACAGAAGTGCCTCCAATTCTTCACAGTAATTTTCCTCATCTTGTACTGGAGAAAATTCTTGTGAGTCTCACTATGAAAAACTGTAAAGCTGCAATGAATTTTTTCCAAAGTGTGCCAGAATGTGAACACCACCGAAAAGATAAAGAAGAACTTTCATTCTCAGAAGTAGAAGAACTATTTCTTCAGACAACTTTTGACAAGATGGACTTTTTAACCATTGTGAGAGAATGTGGTATAGAAAAGCACCAGTCCAGTATTGGCTTCTCTGTCCACCAGAATCTCAAGGAATCATTGGATTGCTATCTTCTGGGATTGTCAGAACAGCTTCTAAATAATTACTCATCTGAGTCTCTAATGCAGTGTGCAGGAGAAAGTATCACTCTGTTTAAAAATAAGACAAATGAGGAATTCAGAATTGGTTCCTTGAGAAATATGATGCATTTATTTACACGTTGCTTGAGCAACTGTACCAAGAAGAGTCCAAATAAGATTGCATCTGGCTTTTTCCTGCGATTGTTAACATCAAAGCTAATGAATGACATTGCAGATATTTGTAAAAGTTTCGCATCCTTAATCAAAAAGCCATTTGACCGTGGAGAAGTAGAATCAATGGAAGAGGATACTAATGGAAATCTAATGGAGGTGGAGGATCAGTCATCCATGAATCTATTTAACGATTACCCTGATAGTAGTGTTAGTGATGCAAATGAACCTGGAGAGAGCCAAAGTACCATAGGTGCCATTAATCCTTTAGCTGAAGAATATCTGTCAAAGCAAGATCTACTCTTCTTAGACATGCTCAAGTTCTTGTGTTTGTGTGTAACTACTGCTCAGACCAATACTGTGTCCTTTAGGGCAGCTGATATTCGGAGGAAATTGTTAATGTTAATTGATTCTAGCACGCTAGACCCTACCAAATCCCTCCACCTGCATATGTATCTAATGCTTTTAAAGGAGCTTCCTGGAGAAGAGTACCCCTTGCCAATGGAAGATGTTGTTGAACTTCTGAAACCACTATCCAATGTGTGTTCTTTGTATCGTCGTGACCAAGATGTTTGTAAAACTATTTTAAACCATGTCCTTCATATAGTGAAAAACCTAGGTCAAAGCAATATGGACTCTGAGAATACAAGGGATGCTCAAGGACAGTTTCTTACAGTAATTGGAGCATTTTGGCATCTAACAAAGGAGAGGAAATATACATTCTCTGTAAGAATGGCCCTAGTAAACTGCCTTAAAACTTTGCTTGAGGCCGATCCTTATTCAAAATGGGCCATTCTTAATGTAATGGGAAAAGACTTTCCTGTAAACGAAGTATTTACACAATTTCTTGCTGATAATCATCACCGAGTTCGAATGTTGGCTGCAGAGTCAATCAATAGATTGTTCCAGGACACGAAGGGAGATTCTTCCACATTACTGAAAGCACTTCCTTTGAGGCTTCAGCAAACAGCTTTTGAAAATGCATACCTGAAAGCTCAGGAAGGAATGAGAGAAATGTCCCATAGTGCTGAGAACCCTGAACCTTTGGATGAAATTTATAATAGAAAATCTGTTTTACTGATGTTGATAGCTGTGGTTTTATCCTGTAGCCCTATCTGTGAAAAACAGGCTTTGTTTGCCCTATGTAAATCTGTGAAGGAGAATGGATTAGAACCTCACCTTGTGAAAAAGGTTTTAGAGAAAGTTTCTGAAACTTTTGGATATAGATGTTTAGAAGACTTTATGGCATCTCATTTAGATTATCTGGTTTTGGAATGGCTAAATCTTCAAGATACTGAATACAACTTATCTTCTTTTCCTTTTATTTTATTAAACTATACAAATATTGAGGATTTCTATAGATCTTGTTATAAGGTTTTGGTTCCACATCTGGTGATTAGAAGTCATTTTGATGAGGTGAAGTCCATTGCTAATCAGATTCAACAGGACTGGAAAAGTCTTCTAACAGACTGCTTTCCAAAGATTCTTGTAAATATTCTTCCTTACTTTGCCTATGAGGGTACAGGAGACAGTGGGATGGCACAGCAAAGAGAGACTGCTACCAAGGTCTATGATATGCTTAAAAGTGAAAACTTACTGGGAAAACAGATCGATCATTTATTCATTAGTAACTTACCAGAGATTGTGGTGGAGTTATTGATGACGTTACATGAGCCAGCAAATTCTAGTGCCAGTCAGAGCACTGACCTCTGTGACTTTTCAGGGCTGGTCTTGAACTCCTGGCCTCAAGTGATTCCCCCGTGTTGGCCAATCAAAGTCCTGGGATTACAGGATTCCTATCAGAAAATTCTTCTTGCCATATGTGAGCAAGCAGCTGAAACAAATAATGTTTATAAGAAGCACAGAATTCTTAAAATATACCACCTGTTCGTTAGTTTATTACTGAAAGATATAAAAAGTGGCTTAGGAGGAGCTTGGGCGTTTGTTCTTCGAGATGTTATTTATACTTTGATTCACTATATCAACCAAAGGCCTTCTCGTATCATGGATGTGTCATTACGTAGCTTCTCCCTTTGTTGTGACTTATTAAGTCAGGTTTGCCAGACAGCAGTGACTTACTGTAAGGATGCTCTAGAAAACCATCTTCATGTTATTGTTGGTACACTTATACCCCTTGTGGATGAGCAGGTGGAAGTTCAGAAACAGGTATTGGACTTGTTGAAATACTTAGTGATAGATAACAAGGATAATGAAAACCTCTATCTCACGATTAAGCTTTTAGATCCTTTTCCTGACCATGTTGTTTTTAAGGATTTGCGTATTGCTCAGCAAAAAATCAAATACAGTAGAGGACCCTTTTCACTCTTGGAGGAAATTAACCATTTTCTCTCAGTAAGTGTTTATGATGCACTTCCATTGACAAGACTTGAAGGACTAAAGGATCTTCGAAGACAACTGGAACTACATAAAGATCAGATGATGGACATTATGAGAGCATCTCAGGATAATCCACAAGATGGGATTATGGTGAAGCTAGTTGTCAATTTGTTGCAGTTATCCAAGATGGCAATAAACCACACTGGTGAAAAAGAAGTTCTAGAGGCTGTTGGAAGCTGCTTGGGAGAAGTGGGTCCTATAGATTTCTCTACCATAGCTATACAACATAGTAAAGATGCATCTTATACCAAGGCCCTTAAGTTATTTGAAGGTAAAGAACTTCAGTGGACCTTCATAATGCTGACCTACCTGAATAACACACTGGTAGAAGATTGTGTCAAAGTTCGATCAGCAGCTGTTACTTGTTTGAAAAACATTTTAGCCACAAAGACTGGACATAGTTTCTGGGAGATTTATAAGATGACAACAGATCCAATGCTGGCCTATCTACAGCCTTTTAGAACATCGAGAAAAAAGTTTTTAGAAGTACCCAGATTTGACAAAGAAAACCCTTTTGAAGGCCTGGATGATATAAATCTGTGGATTCCTCTGAGTGAAAATCATGACATTTGGATAAAGACACTGACTTGTGCTTTTTTGGACAGTGGAGGCACAAAATGTGAAATTCTTCAATTATTAAAGCCAATGTGTGAAGTGAAAACTGACTTTTGTCAGACTGTACTTCCATACTTGATTCATGATATTTTGCTCCAAGATACAAATGAATCATGGAGAAATCTGCTTTCTACACATGTTCAGGGATTTTTCACCAGCTGTCTTCGACACTTCTCACAAACGAGCCGATCCACAACCCCTGCAAACTTGGATTCAGAGTCAGAGCACTTTTTCCGATGCTGTTTGGATAAAAAATCACAAAGAACAATGCTTGGTGTTGTGGACTACATGAGAAGACAAAAGAGACCTTCTTCAGGAACAATTTTTGATGATGCTTTCTGGCTGGATTTAAATTATCTAGAAGTTGCCAAGGTAGCTCAGTCTTGTGCTGCTCACTTTACAGCTTTACTCTATGCAGAAATCTATGCAGATAAGAAAAGCATGGATGATCAAGAGAAAAGAAGTCTTGCATTTGAAGAAGGAAGCCAAAGTACAACTATTTCTAGCTTGAGTGAAAAAAGTAAAGAAGAAACTGGAATAAGTTTACAGGATCTTCTCTTAGAAATCTACAGAAGTATAGGAGAGCCAGATAGTTTGTATGGCTGTGGTGGAGGGAAGATGTTACAACCCATTACTAGACTACGAACATATGAACACGAAGCAATGTGGGGCAAAGCCCTAGTAACATATGACCTTGAAACAGCAATCTCCTCATCAACCCGCCAGGCAGGAATCATTCAGGCCTTGCAGAATTTGGGACTCTGCCATATTCTTTCTGTGTATTTGAAAGGATTAGATTATGAAAATAAAGACTGGTGTCCTGAACTACAGGAACTTCATTACCAAGCAGCATGGAGGAATATGCAGTGGGACCATTGCACTTATGTCAGCAAAGAAATAGAAGGAACCAGTTACCATGAATCATTGTACAATGCTCTACAATCTCTAAGAGACAGAGAATTCTCTACATTTTATGAAAGTCTCAAATATGCAAGAGTAAAAGAAGTGGAAGAGTTGTGTAAGCGCAGCCTTGAGTCTGTGTATTCGCTCTACCCCACACTCAGCAGGTTGCAGGCCATTGGAGAGCTGGAAAGCATTGGGGAGCTTTTCTCAAAATCAGTCACACATAGACAACTCTCTGAAGTATATATTAAGTGGCAGAAACACTCCCAGCTTCTCAAGGACAGTGATTTTAGTTTTCAGGAGCCTATCATGGCTCTACGCACAGTCATTTTGGAGATCCTGATGGAAAAGGAAATAGACAACTCACAAAGAGAGTGTATTAAGGAGATTCTCACCAAACACCTTGTAGAACTCTCTATACTGGCCAGAACTTTCAAGAACACTCAGCTCCCTGAAAGGGCAATATTTCAAATTAAACAGTATAATTCAGTTAGCTGTGGAGTCTCTGAGTGGCAGCTGGAAGAAGCACAAGTATTCTGGGCAAAAAAGGAGCAGAGTCTTGCCCTGAGTATTCTCAAGCAAATGATCAAGAAGTTGGATGCCAGCTGTGCAGCGAACAATCCCAGCCTAAAACTTATATACACAGAATGTCTAAGGGTTTGTGGCAACTGGTTAGCAGAAACTTGCTTAGAAAATCCTGCGGTCATCATGCAGACCTATCTAGAAAAGGCAGTAGAAGTTGCTGGCAATTATGATGGAGAAAGTAATGATGAGCTAAGAAATGGAAAAATGAAGGCATTTCTGTCATTAGCCCGGTTTTCAGATACTCAGTACCAAAGAATTGAAAACTACATGAAATCATCAGAATTTGAAAACAAGCAAGCTCTCCTGAAAAGAGCCAAAGAGGAAGTAGGTCTCCTTAGGGAACATAAAATTCAGACCAACAGATACACAGTAAAAGTTCAGCGAGAGCTGGAGTTGGATGAACTTGCCCTGCGTGCATTGAAAGAGGATCGTAAACGCTTCTTATGTAAAGCAGTTGAAAATTACGTCAACTGCTTATTAAGTGGAGAAGAACATGATATGTGGGTATTCCGACTTTGTTCCCTCTGGCTTGAAAATTCTGGAGTTTCTGAAGTCAATGGCATGATGAAGAGAGATGGAATGAAGATTCCATCATATAAATTTTTGCCTCTTATGTACCAACTGGCTGCTAGAATGGGGACCAAGATGATGGGAGGCCTAGGATTTCATGAAGTCCTCAATAATCTAATCTCTAGAATTTCAATGGATCACCCCCATCATACTTTATTTATTATACTGGCCTTAGCAAATGCAAACAGAGATGAATTTCTGACTAAACCAGAGGTAGCAAGAAGAAGTAGAATAACTAAAAATGCGCCTAAACAAAGCTCTCAGCTTGATGAGGATCGAACAGAGGCTGCAAACAGAATAATATGTACTATCAGAAGTAGGAGACCTCAGATGGTCAGAAGTGTTGAGGCACTTTGTGATGCTTATATTATATTAGCAAACTTAGATGCCACTCAGTGGAAGACTCAGAGAAAAGGCATAAATATTCCAGCAGACCAGCCAATTACTAAACTTAAGAATTTAGAAGATGTTGTTGTCCCTACTATGGAAATTAAGGTGGACCACACAGGAGAATATGGAAATCTCGTGACTATACAGTCATTTAAAGCAGAATTTCGCTTAGCAGGAGGTGTAAATTTACCAAAAATAATAGATTGTGTAGGTTCTGATGGCAAGGAGAGGAGACAGCTTGTTAAGGGCCGTGATGACCTGAGACAAGATGCTGTCATGCAACAGGTCTTCCAGATGTGTAATACATTACTGCAGAGAAACACTGAAACTAGGAAGAGGAAATTAACTATCTGTACTTATAAGGTGGTTCCCCTCTCTCAGCGAAGTGGTGTTCTTGAATGGTGTACAGGAACTATCCCTATTGGTGAATTTCTTGTTAACAATGAAGATGGTGCTCATAAAAGATACAGGCCAAATGATTTCAGTGCCTTTCAATGCCAAAAGAAAATGATGGAGGTGCAAAAAAAGTCTTTTGAAGATAAATATGAAGTCTTCATGGATGTTTGCCAAAATTTTCAACCAGTTTTCCGTTACTTCTGCATGGAAAAATTCTTGGATCCAGCTATTTGGTTTGAGAAGCGATTGGCTTATACGCGCAGTGTAGCCACGTCTTCTATTGTTGGTTACATACTTGGACTTGGTGATAGACATGTACAGAATATCTTGATAAATGAGCAGTCAGCAGAACTTGTACATATAGATTTGGGTGTTGCTTTTGAACAGGGCAAAATCCTTCCTACTCCTGAGACAGTTCCTTTTAGACTCACCAGAGATATTGTGGATGGCATGGGCATTACTGGTGTTGAAGGTGTCTTCAGAAGATGCTGTGAGAAAACCATGGAAGTGATGAGAAACTCTCAGGAAACTCTGTTAACCATTGTAGAGGTCCTTCTGTATGATCCACTCTTTGACTGGACCATGAATCCTTTGAAAGCTTTGTATTTACAGCAGAGGCCAGAAGATGAAACTGAGCTTCACCCTACTCTGAATGCAGATGACCAAGAATGCAAACGAAATCTCAGTGATATTGACCAGAGTTTCAACAAAGTAGCTGAACGTGTCTTAATGAGACTACAAGAGAAACTGAAAGGAGTGGAAGAAGGCACTGTGCTCAGTGTTGGTGGACAAGTGAATCTGCTCATACAGCAGGCCATGGACCCCAAAAATCTCAGCCGACTTTTCCCCGGATGGAAAGCTTGGGTGTGA

▼ KEYWORD

ID	Family
KW-0067	ATP-binding
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-0968	Cytoplasmic vesicle
KW-0227	DNA damage
KW-0418	Kinase
KW-0547	Nucleotide-binding
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0723	Serine/threonine-protein kinase
KW-0808	Transferase

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0000781	Cellular Component	Chromosome, telomeric region
GO:0031410	Cellular Component	Cytoplasmic vesicle
GO:1990391	Cellular Component	DNA repair complex
GO:0005730	Cellular Component	Nucleolus
GO:0016303	Molecular Function	1-phosphatidylinositol-3-kinase activity
GO:0005524	Molecular Function	ATP binding
GO:0004677	Molecular Function	DNA-dependent protein kinase activity
GO:0046983	Molecular Function	Protein dimerization activity
GO:0047485	Molecular Function	Protein N-terminus binding
GO:0044877	Molecular Function	Protein-containing complex binding
GO:0007050	Biological Process	Cell cycle arrest
GO:0071480	Biological Process	Cellular response to gamma radiation
GO:0071500	Biological Process	Cellular response to nitrosative stress
GO:0071481	Biological Process	Cellular response to X-ray
GO:0006975	Biological Process	DNA damage induced protein phosphorylation
GO:0006281	Biological Process	DNA repair
GO:0097694	Biological Process	Establishment of RNA localization to telomere
GO:0071044	Biological Process	Histone mRNA catabolic process
GO:0016572	Biological Process	Histone phosphorylation
GO:0007094	Biological Process	Mitotic spindle assembly checkpoint
GO:0030889	Biological Process	Negative regulation of B cell proliferation
GO:1904354	Biological Process	Negative regulation of telomere capping
GO:1904262	Biological Process	Negative regulation of TORC1 signaling
GO:0036289	Biological Process	Peptidyl-serine autophosphorylation
GO:0043065	Biological Process	Positive regulation of apoptotic process
GO:0030335	Biological Process	Positive regulation of cell migration
GO:0043517	Biological Process	Positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0010628	Biological Process	Positive regulation of gene expression
GO:1904884	Biological Process	Positive regulation of telomerase catalytic core complex assembly
GO:1904358	Biological Process	Positive regulation of telomere maintenance via telomere lengthening
GO:0010506	Biological Process	Regulation of autophagy
GO:0032210	Biological Process	Regulation of telomere maintenance via telomerase
GO:0090399	Biological Process	Replicative senescence
GO:0072434	Biological Process	Signal transduction involved in mitotic G2 DNA damage checkpoint
GO:0000723	Biological Process	Telomere maintenance

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Paa-1380	Papio anubis	95.91	0.0	5867
LLPS-Mam-0882	Macaca mulatta	95.82	0.0	5863
LLPS-Maf-0037	Macaca fascicularis	95.82	0.0	5861
LLPS-Chs-0338	Chlorocebus sabaeus	95.59	0.0	5848
LLPS-Ict-2539	Ictidomys tridecemlineatus	95.49	7e-156	547
LLPS-Man-2619	Macaca nemestrina	95.29	0.0	5779
LLPS-Cea-1207	Cercocebus atys	94.77	0.0	5791
LLPS-Pap-1192	Pan paniscus	94.57	0.0	5786
LLPS-Nol-1839	Nomascus leucogenys	94.57	0.0	5790
LLPS-Hos-0566	Homo sapiens	94.48	0.0	5782
LLPS-Pat-1650	Pan troglodytes	94.38	0.0	5774
LLPS-Rhb-2627	Rhinopithecus bieti	94.21	0.0	5737
LLPS-Gog-2409	Gorilla gorilla	93.07	0.0	5653
LLPS-Poa-3639	Pongo abelii	92.81	0.0	5657
LLPS-Aon-1585	Aotus nancymaae	91.96	0.0	5641
LLPS-Caj-0534	Callithrix jacchus	91.14	0.0	5601
LLPS-Myl-3544	Myotis lucifugus	87.18	0.0	1915
LLPS-Eqc-1738	Equus caballus	86.33	0.0	5313
LLPS-Ova-1088	Ovis aries	86.28	0.0	5306
LLPS-Bot-1781	Bos taurus	86.27	0.0	5298
LLPS-Loa-1272	Loxodonta africana	86.2	0.0	5323
LLPS-Otg-2150	Otolemur garnettii	86.18	0.0	5251
LLPS-Cas-0351	Carlito syrichta	86.18	0.0	5279
LLPS-Caf-2749	Canis familiaris	85.97	0.0	5286
LLPS-Fec-1933	Felis catus	85.42	0.0	5263
LLPS-Orc-1700	Oryctolagus cuniculus	85.39	0.0	5250
LLPS-Aim-3254	Ailuropoda melanoleuca	85.33	0.0	5243
LLPS-Urm-0328	Ursus maritimus	85.28	0.0	5243
LLPS-Mup-0014	Mustela putorius furo	85.16	0.0	5252
LLPS-Sus-1154	Sus scrofa	85.12	0.0	5240
LLPS-Dio-0569	Dipodomys ordii	84.51	0.0	5145
LLPS-Fud-0929	Fukomys damarensis	84.47	0.0	5163
LLPS-Cap-0760	Cavia porcellus	82.93	0.0	5026
LLPS-Mea-2828	Mesocricetus auratus	80.73	0.0	4899
LLPS-Ran-3270	Rattus norvegicus	80.55	0.0	4961
LLPS-Mum-0950	Mus musculus	80.53	0.0	4929
LLPS-Mod-0875	Monodelphis domestica	77.82	0.0	4769
LLPS-Sah-0051	Sarcophilus harrisii	77.42	0.0	4747
LLPS-Ora-0950	Ornithorhynchus anatinus	76.87	0.0	1617
LLPS-Pes-0748	Pelodiscus sinensis	69.72	0.0	4217
LLPS-Gaga-3396	Gallus gallus	66.88	0.0	4051
LLPS-Fia-2755	Ficedula albicollis	66.8	0.0	4080
LLPS-Tag-0104	Taeniopygia guttata	66.73	0.0	4118
LLPS-Anp-0094	Anas platyrhynchos	66.49	0.0	4061
LLPS-Meg-1280	Meleagris gallopavo	63.13	0.0	3740
LLPS-Xet-0621	Xenopus tropicalis	62.07	0.0	3787
LLPS-Cii-1682	Ciona intestinalis	60.3	1e-103	341
LLPS-Lac-1369	Latimeria chalumnae	56.6	0.0	2595
LLPS-Xim-0450	Xiphophorus maculatus	55.43	0.0	2236
LLPS-Scf-2844	Scleropages formosus	53.87	0.0	3071
LLPS-Coc-1398	Corchorus capsularis	53.57	8e-61	218
LLPS-Ten-1496	Tetraodon nigroviridis	53.3	0.0	2210
LLPS-Cis-1637	Ciona savignyi	52.91	3e-121	396
LLPS-Orn-0729	Oreochromis niloticus	52.21	0.0	3044
LLPS-Asm-2661	Astyanax mexicanus	52.02	0.0	3000
LLPS-Dar-0356	Danio rerio	51.93	0.0	2965
LLPS-Pof-1541	Poecilia formosa	51.88	0.0	3011
LLPS-Icp-2814	Ictalurus punctatus	51.64	0.0	3003
LLPS-Gaa-1456	Gasterosteus aculeatus	50.51	0.0	2869
LLPS-Orl-1157	Oryzias latipes	49.84	7e-94	315
LLPS-Cus-1073	Cucumis sativus	45.21	2e-158	511
LLPS-Osl-0264	Ostreococcus lucimarinus	45.06	3e-107	356
LLPS-Chr-0209	Chlamydomonas reinhardtii	44.41	4e-66	255
LLPS-Org-0046	Oryza glaberrima	40.96	9e-08	62.0
LLPS-Sem-0085	Selaginella moellendorffii	40.72	3e-167	542
LLPS-Bro-1415	Brassica oleracea	40.3	3e-163	566
LLPS-Viv-1660	Vitis vinifera	40.18	6e-168	556
LLPS-Gas-0357	Galdieria sulphuraria	36.45	7e-128	457
LLPS-Pot-0957	Populus trichocarpa	35.86	0.0	648
LLPS-Met-2146	Medicago truncatula	35.23	3e-59	232
LLPS-Php-0106	Physcomitrella patens	35.14	2e-60	236
LLPS-Scp-0629	Schizosaccharomyces pombe	34.87	2e-129	463
LLPS-Gor-1762	Gossypium raimondii	34.35	2e-179	624
LLPS-Phv-0166	Phaseolus vulgaris	34.28	2e-60	235
LLPS-Ors-1717	Oryza sativa	34.03	2e-60	224
LLPS-Brn-3303	Brassica napus	33.96	3e-164	544
LLPS-Thc-1612	Theobroma cacao	33.8	1e-59	233
LLPS-Amt-0181	Amborella trichopoda	33.69	2e-165	551
LLPS-Ori-2163	Oryza indica	33.65	3e-172	600
LLPS-Orni-1691	Oryza nivara	33.36	1e-180	626
LLPS-Lep-0321	Leersia perrieri	33.33	0.0	630
LLPS-Pug-1222	Puccinia graminis	32.99	6e-60	234
LLPS-Brr-1110	Brassica rapa	32.95	2e-165	579
LLPS-Hov-1187	Hordeum vulgare	32.75	7e-157	552
LLPS-Sei-1505	Setaria italica	32.72	9e-164	544
LLPS-Orb-0589	Oryza barthii	32.38	5e-171	596
LLPS-Fuo-1125	Fusarium oxysporum	32.23	2e-102	355
LLPS-Orr-1185	Oryza rufipogon	32.06	2e-168	588
LLPS-Sac-0648	Saccharomyces cerevisiae	31.96	6e-93	343
LLPS-Orbr-1044	Oryza brachyantha	31.86	1e-179	623
LLPS-Spr-1088	Sporisorium reilianum	31.73	7e-134	478
LLPS-Usm-1446	Ustilago maydis	31.57	9e-134	477
LLPS-Mua-0722	Musa acuminata	31.56	0.0	630
LLPS-Orgl-1108	Oryza glumaepatula	31.55	2e-159	559
LLPS-Cae-1112	Caenorhabditis elegans	31.43	1e-63	247
LLPS-Prp-1888	Prunus persica	31.36	0.0	659
LLPS-Sol-0591	Solanum lycopersicum	31.36	0.0	671
LLPS-Art-2717	Arabidopsis thaliana	31.29	0.0	662
LLPS-Zem-1234	Zea mays	31.16	5e-167	585
LLPS-Tum-0137	Tuber melanosporum	31.13	3e-148	514
LLPS-Trr-0661	Trichoderma reesei	31.01	6e-133	474
LLPS-Trv-0145	Trichoderma virens	30.67	7e-132	471
LLPS-Glm-0805	Glycine max	30.47	0.0	684
LLPS-Asn-1254	Aspergillus nidulans	30.47	4e-141	500
LLPS-Yal-0651	Yarrowia lipolytica	30.35	3e-87	324
LLPS-Via-1324	Vigna angularis	30.04	0.0	662
LLPS-Fuv-0878	Fusarium verticillioides	29.98	8e-126	450
LLPS-Asg-0388	Ashbya gossypii	29.97	4e-90	334
LLPS-Pyt-0669	Pyrenophora teres	29.9	7e-131	468
LLPS-Asc-0980	Aspergillus clavatus	29.83	2e-139	496
LLPS-Fus-1259	Fusarium solani	29.82	3e-128	459
LLPS-Scj-1353	Schizosaccharomyces japonicus	29.73	1e-64	249
LLPS-Beb-0671	Beauveria bassiana	29.66	1e-136	486
LLPS-Crn-0867	Cryptococcus neoformans	29.6	6e-65	251
LLPS-Aso-0725	Aspergillus oryzae	29.58	6e-133	474
LLPS-Pytr-1173	Pyrenophora triticirepentis	29.57	1e-131	470
LLPS-Ved-1405	Verticillium dahliae	29.54	7e-129	461
LLPS-Asf-0236	Aspergillus flavus	29.51	4e-134	474
LLPS-Orp-0732	Oryza punctata	29.5	7e-130	464
LLPS-Lem-0344	Leptosphaeria maculans	29.5	4e-134	478
LLPS-Blg-1147	Blumeria graminis	29.49	2e-127	456
LLPS-Scc-0179	Schizosaccharomyces cryophilus	29.47	2e-126	453
LLPS-Ast-0506	Aspergillus terreus	29.44	3e-134	478
LLPS-Cog-1137	Colletotrichum gloeosporioides	29.35	8e-127	454
LLPS-Nef-0662	Neosartorya fischeri	29.3	4e-137	488
LLPS-Put-0468	Puccinia triticina	29.25	5e-120	428
LLPS-Coo-0915	Colletotrichum orbiculare	29.22	5e-131	468
LLPS-Phn-1273	Phaeosphaeria nodorum	29.01	7e-131	467
LLPS-Tru-0207	Triticum urartu	28.95	8e-135	481
LLPS-Nec-0391	Neurospora crassa	28.89	7e-133	474
LLPS-Scs-0608	Sclerotinia sclerotiorum	28.85	8e-127	454
LLPS-Dos-0357	Dothistroma septosporum	28.84	6e-118	425
LLPS-Asfu-0771	Aspergillus fumigatus	28.79	1e-135	483
LLPS-Cogr-1511	Colletotrichum graminicola	28.46	3e-125	449
LLPS-Mae-1475	Manihot esculenta	28.34	0.0	671
LLPS-Hea-1586	Helianthus annuus	28.34	5e-59	231
LLPS-Mao-0347	Magnaporthe oryzae	28.32	1e-126	454
LLPS-Miv-1131	Microbotryum violaceum	28.27	2e-122	440
LLPS-Gag-1046	Gaeumannomyces graminis	28.23	8e-60	234
LLPS-Leo-0519	Lepisosteus oculatus	28.05	1e-59	233
LLPS-Dac-0264	Daucus carota	27.69	0.0	650
LLPS-Arl-1029	Arabidopsis lyrata	27.68	0.0	647
LLPS-Zyt-0206	Zymoseptoria tritici	27.67	4e-117	422
LLPS-Drm-0429	Drosophila melanogaster	27.66	4e-142	504
LLPS-Kop-0432	Komagataella pastoris	27.44	2e-95	351
LLPS-Brd-0898	Brachypodium distachyon	26.87	4e-177	617
LLPS-Map-0914	Magnaporthe poae	26.63	5e-106	386
LLPS-Sob-1267	Sorghum bicolor	26.59	6e-176	613
LLPS-Chc-0381	Chondrus crispus	26.1	2e-123	444
LLPS-Scm-3174	Scophthalmus maximus	24.48	5e-75	284
LLPS-Tar-0735	Takifugu rubripes	23.95	2e-65	252

LLPS-Mal-0322ATM

Protein Sequence

Nucleotide Sequence

LLPS-Mal-0322
ATM