• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Icp-3299
hmbs

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: porphobilinogen deaminase isoform X2
Gene Name: hmbs
Ensembl Gene: ENSIPUG00000008899.1
Ensembl Protein: ENSIPUP00000013062.1
Organism: Ictalurus punctatus
Taxa ID: 7998
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSQEARTTEE  ENGKVTRIIR  IGTRKSQLAR  IQTDSVAEQL  KKLYPDLQLE  IVAMSTVGDK  60
61    ILDTALSKIG  EKSLFTKELE  NALERNEVDL  VVHSLKDLPT  SLPPGFTIGA  VLQRENPHDA  120
121   VVLHPKNAGL  TLDALPENSV  IGTSSLRRAA  QLKKRFPQLE  FENIRGNLNT  RLKKLDEKDD  180
181   YAAIILAAAG  LKRMGWESRI  SQVLGPEDCM  YAVGQGALAV  EVRARDRDIL  KMVSILHHPD  240
241   TVLRCISERA  FLKQLEGGCS  VPVAVYTEMK  NSVLYLTGAV  YSLDGADCLK  DTMQTNIELD  300
301   NMVHDSAEDR  AHVGVTANNL  SLKALDDAEN  LGVDLANLLL  SKGAKDILTT  ARQLNDVR  358
Nucleotide CDS Sequence (FASTA)
1     ATGTCTCAAG  AAGCTAGAAC  TACAGAAGAA  GAAAATGGAA  AAGTCACTCG  GATTATTCGC  60
61    ATCGGAACCA  GGAAAAGCCA  GCTTGCTCGG  ATTCAGACAG  ACAGCGTGGC  CGAGCAGCTG  120
121   AAAAAGCTCT  ATCCAGACTT  GCAGCTAGAG  ATAGTTGCCA  TGTCGACAGT  CGGAGACAAA  180
181   ATCCTTGACA  CTGCCTTATC  AAAGATTGGA  GAGAAGAGTC  TGTTCACCAA  AGAGCTGGAG  240
241   AATGCCCTTG  AGAGAAACGA  ACGTGAAAAT  CCTCATGATG  CTGTAGTGCT  TCATCCAAAG  300
301   AATGCTGGAC  TCACTTTGGA  CGCCCTTCCA  GAAAATAGTG  TGATTGGCAC  GAGCTCGCTC  360
361   CGCCGAGCGG  CACAGCTGAA  AAAAAGGTTC  CCACAGCTGG  AATTTGAAAA  CATTAGAGGC  420
421   AACCTGAATA  CTCGTCTGAA  GAAGCTGGAC  GAGAAGGATG  ACTATGCTGC  CATCATTCTG  480
481   GCTGCAGCTG  GTCTCAAGCG  CATGGGCTGG  GAGAGCCGTA  TCAGTCAGGT  TCTGGGTCCT  540
541   GAAGACTGCA  TGTATGCTGT  AGGCCAGGGA  GCGTTGGCGG  TGGAAGTGAG  GGCAAGAGAC  600
601   AGAGACATCC  TCAAGATGGT  GTCCATCCTC  CACCACCCTG  ACACTGTGCT  GCGCTGCATC  660
661   TCTGAGAGGG  CTTTCCTCAA  GCAACTGGAG  GGAGGCTGCA  GTGTACCTGT  CGCTGTCTAC  720
721   ACAGAAATGA  AGAACTCTGT  GCTCTATCTG  ACAGGTGCAG  TTTACAGTCT  GGATGGTGCT  780
781   GACTGCTTGA  AGGACACCAT  GCAAACCAAC  ATCGAATTAG  ATAACATGGT  GCATGACAGT  840
841   GCAGAAGACC  GAGCTCATGT  CGGAGTCACG  GCCAACAACC  TATCTCTGAA  GGCTCTGGAT  900
901   GATGCAGAGA  ATCTGGGTGT  TGATCTTGCC  AACCTGCTGC  TCAGTAAAGG  AGCCAAGGAC  960
961   ATCCTTACCA  CGGCCAGACA  GCTCAATGAT  GTCCGATAA  999

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orn-1656Oreochromis niloticus79.60.0 549
LLPS-Asm-3343Astyanax mexicanus79.150.0 563
LLPS-Leo-1875Lepisosteus oculatus78.930.0 548
LLPS-Ten-1146Tetraodon nigroviridis78.830.0 543
LLPS-Orl-3526Oryzias latipes78.740.0 533
LLPS-Scm-3685Scophthalmus maximus78.360.0 549
LLPS-Tar-2159Takifugu rubripes77.250.0 528
LLPS-Gaa-0202Gasterosteus aculeatus76.550.0 550
LLPS-Scf-2800Scleropages formosus76.140.0 549
LLPS-Pof-2438Poecilia formosa75.830.0 525
LLPS-Tag-2934Taeniopygia guttata75.80.0 523
LLPS-Fia-0401Ficedula albicollis75.80.0 524
LLPS-Xim-3236Xiphophorus maculatus75.647e-172 490
LLPS-Anp-3036Anas platyrhynchos75.234e-178 505
LLPS-Dar-3986Danio rerio74.860.0 540
LLPS-Gaga-2331Gallus gallus73.730.0 528
LLPS-Meg-1847Meleagris gallopavo73.417e-180 511
LLPS-Pes-3247Pelodiscus sinensis73.16e-178 505
LLPS-Anc-1661Anolis carolinensis71.016e-169 483
LLPS-Cap-2768Cavia porcellus70.345e-180 511
LLPS-Caj-4615Callithrix jacchus70.250.0 513
LLPS-Fud-2397Fukomys damarensis70.24e-179 509
LLPS-Gog-1911Gorilla gorilla70.091e-175 499
LLPS-Pap-3827Pan paniscus70.092e-175 499
LLPS-Rhb-3903Rhinopithecus bieti70.093e-175 498
LLPS-Aim-4193Ailuropoda melanoleuca69.835e-179 508
LLPS-Nol-2800Nomascus leucogenys69.727e-163 466
LLPS-Mup-4458Mustela putorius furo69.714e-179 509
LLPS-Fec-3905Felis catus69.691e-178 507
LLPS-Urm-3200Ursus maritimus69.549e-178 505
LLPS-Myl-0067Myotis lucifugus69.437e-175 498
LLPS-Paa-2197Papio anubis69.412e-178 507
LLPS-Sus-1943Sus scrofa69.417e-178 506
LLPS-Maf-3146Macaca fascicularis69.412e-178 507
LLPS-Chs-2768Chlorocebus sabaeus69.412e-178 507
LLPS-Mam-4427Macaca mulatta69.412e-178 507
LLPS-Man-4665Macaca nemestrina69.412e-178 507
LLPS-Eqc-4682Equus caballus69.341e-177 505
LLPS-Ora-1477Ornithorhynchus anatinus69.233e-38 139
LLPS-Mal-0713Mandrillus leucophaeus69.128e-178 505
LLPS-Poa-2209Pongo abelii69.124e-178 506
LLPS-Hos-3423Homo sapiens69.123e-178 506
LLPS-Pat-2518Pan troglodytes69.123e-178 506
LLPS-Otg-4149Otolemur garnettii69.125e-176 501
LLPS-Ran-2739Rattus norvegicus69.016e-180 511
LLPS-Mum-4735Mus musculus69.018e-180 510
LLPS-Ere-0807Erinaceus europaeus68.979e-176 500
LLPS-Caf-0790Canis familiaris68.933e-176 501
LLPS-Ova-3912Ovis aries68.843e-176 501
LLPS-Dio-4183Dipodomys ordii68.753e-176 501
LLPS-Bot-4595Bos taurus68.683e-174 496
LLPS-Cas-2960Carlito syrichta68.648e-177 503
LLPS-Ict-4361Ictidomys tridecemlineatus68.381e-175 500
LLPS-Mod-2323Monodelphis domestica68.291e-172 492
LLPS-Mea-2719Mesocricetus auratus68.087e-176 500
LLPS-Orc-0385Oryctolagus cuniculus68.081e-175 500
LLPS-Sah-3941Sarcophilus harrisii67.611e-173 495
LLPS-Loa-0152Loxodonta africana66.951e-171 490
LLPS-Tut-1336Tursiops truncatus66.465e-147 426
LLPS-Xet-3532Xenopus tropicalis65.723e-156 451
LLPS-Cea-2468Cercocebus atys65.622e-163 468
LLPS-Aon-4500Aotus nancymaae59.893e-137 402
LLPS-Lac-2016Latimeria chalumnae59.49e-132 389
LLPS-Drm-1210Drosophila melanogaster57.51e-97 310
LLPS-Cis-1865Ciona savignyi55.367e-122 363
LLPS-Cii-1856Ciona intestinalis54.245e-121 361
LLPS-Abg-1901Absidia glauca50.883e-103 314
LLPS-Spr-1437Sporisorium reilianum47.281e-55 199
LLPS-Usm-1207Ustilago maydis45.913e-56 201
LLPS-Trv-1087Trichoderma virens45.293e-70 229
LLPS-Beb-0976Beauveria bassiana45.262e-72 236
LLPS-Blg-1215Blumeria graminis44.716e-83 262
LLPS-Tum-0922Tuber melanosporum44.587e-85 268
LLPS-Scs-1124Sclerotinia sclerotiorum44.328e-82 261
LLPS-Scj-1597Schizosaccharomyces japonicus43.375e-78 249
LLPS-Sac-1443Saccharomyces cerevisiae42.911e-74 240
LLPS-Cogr-1083Colletotrichum graminicola42.863e-77 248
LLPS-Coo-1517Colletotrichum orbiculare42.573e-77 248
LLPS-Fus-0544Fusarium solani42.436e-76 244
LLPS-Mel-0790Melampsora laricipopulina42.395e-77 250
LLPS-Ved-1525Verticillium dahliae42.375e-76 245
LLPS-Gag-0789Gaeumannomyces graminis42.351e-73 238
LLPS-Zyt-0054Zymoseptoria tritici42.291e-79 254
LLPS-Asc-0393Aspergillus clavatus42.063e-77 248
LLPS-Dos-0113Dothistroma septosporum41.586e-79 254
LLPS-Nec-0888Neurospora crassa41.576e-73 236
LLPS-Sem-1618Selaginella moellendorffii41.53e-58 199
LLPS-Scp-1659Schizosaccharomyces pombe41.472e-72 235
LLPS-Asfu-0779Aspergillus fumigatus41.296e-81 257
LLPS-Gas-1135Galdieria sulphuraria41.128e-57 196
LLPS-Lem-1487Leptosphaeria maculans41.092e-69 229
LLPS-Nia-1836Nicotiana attenuata40.966e-57 196
LLPS-Kop-1106Komagataella pastoris40.832e-76 246
LLPS-Crn-0983Cryptococcus neoformans40.773e-55 194
LLPS-Ast-1248Aspergillus terreus40.778e-70 229
LLPS-Fuv-0769Fusarium verticillioides40.752e-76 245
LLPS-Aso-1024Aspergillus oryzae40.721e-78 251
LLPS-Fuo-1075Fusarium oxysporum40.632e-76 245
LLPS-Asni-1126Aspergillus niger40.63e-74 240
LLPS-Scc-1378Schizosaccharomyces cryophilus40.593e-75 243
LLPS-Sob-1545Sorghum bicolor40.552e-53 185
LLPS-Pug-1063Puccinia graminis40.491e-70 234
LLPS-Pytr-1547Pyrenophora triticirepentis40.465e-69 228
LLPS-Nef-0209Neosartorya fischeri40.421e-77 248
LLPS-Pyt-0583Pyrenophora teres40.42e-69 229
LLPS-Yal-1191Yarrowia lipolytica40.44e-76 244
LLPS-Asg-0816Ashbya gossypii40.366e-76 244
LLPS-Sot-1287Solanum tuberosum40.274e-56 193
LLPS-Sol-1058Solanum lycopersicum40.272e-56 194
LLPS-Trr-0743Trichoderma reesei40.244e-69 227
LLPS-Mao-0807Magnaporthe oryzae40.232e-70 230
LLPS-Tra-0164Triticum aestivum40.212e-58 199
LLPS-Dac-0744Daucus carota40.151e-51 182
LLPS-Brd-1331Brachypodium distachyon40.072e-56 194
LLPS-Asn-1263Aspergillus nidulans40.06e-74 239
LLPS-Put-1278Puccinia triticina39.954e-68 228
LLPS-Met-2608Medicago truncatula39.933e-51 181
LLPS-Osl-0716Ostreococcus lucimarinus39.782e-57 196
LLPS-Zem-1498Zea mays39.671e-51 183
LLPS-Chr-1599Chlamydomonas reinhardtii39.648e-57 195
LLPS-Mae-1627Manihot esculenta39.593e-54 189
LLPS-Hea-1303Helianthus annuus39.532e-53 186
LLPS-Art-0727Arabidopsis thaliana39.531e-52 184
LLPS-Orbr-0856Oryza brachyantha39.531e-48 171
LLPS-Php-1614Physcomitrella patens39.474e-60 205
LLPS-Phn-0880Phaeosphaeria nodorum39.443e-73 239
LLPS-Cog-0444Colletotrichum gloeosporioides39.415e-56 192
LLPS-Tru-0338Triticum urartu39.312e-53 184
LLPS-Hov-2166Hordeum vulgare39.182e-56 194
LLPS-Mua-1403Musa acuminata39.02e-54 190
LLPS-Asf-0920Aspergillus flavus38.992e-72 235
LLPS-Via-2292Vigna angularis38.874e-50 177
LLPS-Arl-2441Arabidopsis lyrata38.852e-51 181
LLPS-Sei-2443Setaria italica38.839e-53 184
LLPS-Prp-0287Prunus persica38.723e-54 189
LLPS-Pot-1975Populus trichocarpa38.71e-53 187
LLPS-Ori-2365Oryza indica38.672e-56 194
LLPS-Org-0884Oryza glaberrima38.676e-56 192
LLPS-Ors-1853Oryza sativa38.676e-56 192
LLPS-Vir-2118Vigna radiata38.549e-53 185
LLPS-Brn-0622Brassica napus38.441e-51 182
LLPS-Lep-1792Leersia perrieri38.413e-58 199
LLPS-Glm-2907Glycine max38.361e-53 186
LLPS-Gor-1063Gossypium raimondii38.365e-47 169
LLPS-Amt-0563Amborella trichopoda38.332e-56 196
LLPS-Orm-1722Oryza meridionalis38.192e-54 189
LLPS-Orp-0476Oryza punctata38.192e-54 189
LLPS-Bro-3039Brassica oleracea38.12e-51 181
LLPS-Brr-2178Brassica rapa38.14e-51 181
LLPS-Cus-0970Cucumis sativus38.012e-47 170
LLPS-Thc-1772Theobroma cacao37.883e-46 167
LLPS-Phv-0417Phaseolus vulgaris37.674e-52 182
LLPS-Orgl-0854Oryza glumaepatula37.548e-53 185
LLPS-Orb-1353Oryza barthii37.548e-53 185
LLPS-Orni-1645Oryza nivara37.548e-53 185
LLPS-Coc-1991Corchorus capsularis37.541e-45 166
LLPS-Orr-0772Oryza rufipogon37.549e-53 184
LLPS-Miv-0778Microbotryum violaceum37.34e-71 236
LLPS-Cym-0322Cyanidioschyzon merolae37.277e-48 173
LLPS-Viv-0790Vitis vinifera37.097e-51 178
LLPS-Chc-1069Chondrus crispus36.08e-0854.7