• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-4183
Hmbs

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: porphobilinogen deaminase isoform X1
Gene Name: Hmbs
Ensembl Gene: ENSDORG00000001976.2
Ensembl Protein: ENSDORP00000001856.2
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSGNGGVAVT  AEENNLKMRV  IRVGTRKSQL  ARIQTDTVVA  MLKTFYPGVQ  FEIIAMSTTG  60
61    DKILDTALSK  IGEKSLFTKE  LEYALGKNEV  DLVVHSLKDL  PTVLPPGFTI  GAICKRENPC  120
121   DAVVFHPKFV  GKTLETLPER  SVVGTSSLRR  AAQLQRKFPH  LEFKSIRGNL  NTRLRKLDEQ  180
181   QEFSAIILAV  AGLYRMGWQN  RVGQILHPEE  CMYAVGQGAL  GVEVRAKDQD  ILDLVSVLHD  240
241   PETLLRCIAE  RAFLRHLEGG  CSVPVAVHTV  MKDGQLYLTG  GVWSLDGSDS  MQETMQTTIH  300
301   APAQHEDGPE  DDPQMVGITA  RNIPRRAQLA  AENLGISLAS  LLLNKGAKNI  LDVARQLNDA  360
361   R  361
Nucleotide CDS Sequence (FASTA)
1     CCCAGAGGCT  CAGGTGGCCA  TACAGCAGAG  GAAGAGAACA  ACTTGAAGAT  GAGAGTGATT  60
61    CGAGTGGGTA  CCCGTAAGAG  CCAGCTGGCT  CGCATACAGA  CAGATACTGT  GGTAGCAATG  120
121   CTGAAAACCT  TCTACCCTGG  CGTGCAGTTT  GAAATCATTG  CCATGTCTAC  CACAGGAGAC  180
181   AAGATACTTG  ACACTGCACT  CTCTAAGATT  GGGGAAAAGA  GCCTGTTTAC  CAAGGAGCTG  240
241   GAGTACGCTC  TGGGGAAAAA  TGAAGTGGAC  CTGGTTGTTC  ATTCCCTGAA  GGACCTGCCT  300
301   ACTGTGCTGC  CTCCTGGCTT  CACCATCGGA  GCCATCTGCA  AGCGAGAAAA  CCCCTGTGAT  360
361   GCTGTTGTCT  TTCACCCCAA  ATTTGTTGGG  AAAACCCTAG  AAACCTTGCC  AGAGAGGAGT  420
421   GTAGTGGGGA  CCAGCTCCCT  TCGGAGAGCA  GCTCAGCTGC  AGAGAAAGTT  CCCACATCTG  480
481   GAGTTCAAGA  GTATTCGAGG  AAACCTCAAC  ACCCGGCTTC  GGAAGCTGGA  TGAGCAACAG  540
541   GAGTTCAGTG  CCATCATCCT  GGCTGTAGCT  GGCCTGTACC  GCATGGGCTG  GCAGAACCGA  600
601   GTGGGGCAGA  TTTTGCATCC  TGAAGAATGC  ATGTATGCTG  TGGGTCAGGG  GGCCCTAGGT  660
661   GTGGAAGTCC  GAGCCAAGGA  CCAGGATATT  TTGGATCTAG  TGAGTGTGTT  GCATGATCCA  720
721   GAGACTCTGC  TTCGCTGCAT  CGCCGAAAGA  GCCTTCCTGA  GGCATCTGGA  AGGAGGCTGC  780
781   AGCGTGCCAG  TGGCAGTCCA  TACAGTGATG  AAGGATGGAC  AACTGTACCT  GACTGGTGGA  840
841   GTCTGGAGTC  TAGATGGTTC  AGATAGCATG  CAGGAGACCA  TGCAGACCAC  CATCCACGCT  900
901   CCTGCTCAGC  ATGAAGATGG  CCCAGAGGAT  GACCCGCAAA  TGGTAGGCAT  CACTGCTCGA  960
961   AACATTCCAC  GACGAGCCCA  GCTGGCTGCT  GAGAACCTGG  GCATCAGCTT  GGCCAGCTTG  1020
1021  TTATTGAACA  AAGGAGCCAA  GAACATCCTG  GATGTTGCAC  GGCAGCTTAA  TGATGCCCGC  1080
1081  TAA  1083

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ict-4361Ictidomys tridecemlineatus93.140.0 670
LLPS-Gog-1911Gorilla gorilla93.00.0 657
LLPS-Mea-2719Mesocricetus auratus92.760.0 690
LLPS-Pap-3827Pan paniscus92.710.0 657
LLPS-Eqc-4682Equus caballus92.550.0 666
LLPS-Ran-2739Rattus norvegicus92.520.0 689
LLPS-Mum-4735Mus musculus92.520.0 692
LLPS-Mup-4458Mustela putorius furo92.50.0 682
LLPS-Otg-4149Otolemur garnettii92.50.0 685
LLPS-Aim-4193Ailuropoda melanoleuca92.220.0 681
LLPS-Fec-3905Felis catus92.220.0 680
LLPS-Rhb-3903Rhinopithecus bieti92.130.0 653
LLPS-Hos-3423Homo sapiens91.940.0 681
LLPS-Pat-2518Pan troglodytes91.940.0 681
LLPS-Urm-3200Ursus maritimus91.940.0 679
LLPS-Caf-0790Canis familiaris91.690.0 677
LLPS-Sus-1943Sus scrofa91.670.0 682
LLPS-Cas-2960Carlito syrichta91.670.0 682
LLPS-Maf-3146Macaca fascicularis91.390.0 678
LLPS-Chs-2768Chlorocebus sabaeus91.390.0 678
LLPS-Mam-4427Macaca mulatta91.390.0 678
LLPS-Man-4665Macaca nemestrina91.390.0 678
LLPS-Nol-2800Nomascus leucogenys91.270.0 627
LLPS-Mal-0713Mandrillus leucophaeus91.110.0 677
LLPS-Paa-2197Papio anubis91.110.0 674
LLPS-Poa-2209Pongo abelii91.110.0 676
LLPS-Fud-2397Fukomys damarensis90.810.0 676
LLPS-Caj-4615Callithrix jacchus90.280.0 674
LLPS-Myl-0067Myotis lucifugus90.030.0 649
LLPS-Ere-0807Erinaceus europaeus90.00.0 666
LLPS-Orc-0385Oryctolagus cuniculus89.970.0 670
LLPS-Loa-0152Loxodonta africana89.810.0 664
LLPS-Bot-4595Bos taurus89.440.0 670
LLPS-Cap-2768Cavia porcellus89.440.0 659
LLPS-Ova-3912Ovis aries89.170.0 669
LLPS-Tut-1336Tursiops truncatus87.540.0 580
LLPS-Cea-2468Cercocebus atys87.390.0 620
LLPS-Mod-2323Monodelphis domestica85.630.0 630
LLPS-Ora-1477Ornithorhynchus anatinus83.876e-48 164
LLPS-Sah-3941Sarcophilus harrisii83.330.0 620
LLPS-Tag-2934Taeniopygia guttata77.260.0 559
LLPS-Anp-3036Anas platyrhynchos77.110.0 539
LLPS-Fia-0401Ficedula albicollis76.970.0 555
LLPS-Gaga-2331Gallus gallus76.720.0 559
LLPS-Aon-4500Aotus nancymaae76.420.0 534
LLPS-Meg-1847Meleagris gallopavo76.020.0 538
LLPS-Pes-3247Pelodiscus sinensis75.150.0 533
LLPS-Leo-1875Lepisosteus oculatus74.720.0 528
LLPS-Anc-1661Anolis carolinensis73.780.0 517
LLPS-Dar-3986Danio rerio73.620.0 514
LLPS-Orl-3526Oryzias latipes72.892e-174 497
LLPS-Gaa-0202Gasterosteus aculeatus72.251e-178 508
LLPS-Tar-2159Takifugu rubripes71.973e-170 486
LLPS-Orn-1656Oreochromis niloticus71.873e-179 509
LLPS-Ten-1146Tetraodon nigroviridis71.788e-178 506
LLPS-Asm-3343Astyanax mexicanus71.110.0 518
LLPS-Scm-3685Scophthalmus maximus70.411e-173 495
LLPS-Pof-2438Poecilia formosa69.818e-169 483
LLPS-Scf-2800Scleropages formosus69.123e-173 494
LLPS-Icp-3299Ictalurus punctatus68.754e-169 483
LLPS-Xet-3532Xenopus tropicalis66.956e-165 473
LLPS-Xim-3236Xiphophorus maculatus66.212e-155 448
LLPS-Lac-2016Latimeria chalumnae58.921e-134 395
LLPS-Cis-1865Ciona savignyi57.931e-123 367
LLPS-Cii-1856Ciona intestinalis55.461e-120 360
LLPS-Drm-1210Drosophila melanogaster55.368e-92 295
LLPS-Beb-0976Beauveria bassiana49.824e-78 250
LLPS-Abg-1901Absidia glauca49.284e-100 306
LLPS-Scp-1659Schizosaccharomyces pombe46.723e-73 237
LLPS-Spr-1437Sporisorium reilianum46.198e-55 197
LLPS-Cogr-1083Colletotrichum graminicola45.43e-82 261
LLPS-Usm-1207Ustilago maydis44.921e-53 194
LLPS-Blg-1215Blumeria graminis44.674e-84 266
LLPS-Zyt-0054Zymoseptoria tritici44.613e-82 261
LLPS-Scj-1597Schizosaccharomyces japonicus44.257e-78 249
LLPS-Gag-0789Gaeumannomyces graminis43.871e-75 244
LLPS-Miv-0778Microbotryum violaceum43.83e-64 219
LLPS-Trv-1087Trichoderma virens43.533e-77 248
LLPS-Ved-1525Verticillium dahliae43.34e-79 253
LLPS-Asf-0920Aspergillus flavus43.249e-74 239
LLPS-Crn-0983Cryptococcus neoformans43.212e-55 194
LLPS-Scs-1124Sclerotinia sclerotiorum43.193e-78 251
LLPS-Fus-0544Fusarium solani43.12e-79 253
LLPS-Trr-0743Trichoderma reesei43.072e-75 243
LLPS-Dos-0113Dothistroma septosporum43.051e-78 253
LLPS-Coo-1517Colletotrichum orbiculare42.982e-77 248
LLPS-Kop-1106Komagataella pastoris42.941e-82 262
LLPS-Tum-0922Tuber melanosporum42.949e-81 257
LLPS-Aso-1024Aspergillus oryzae42.764e-72 234
LLPS-Nef-0209Neosartorya fischeri42.612e-71 232
LLPS-Asni-1126Aspergillus niger42.434e-78 250
LLPS-Nec-0888Neurospora crassa42.321e-74 241
LLPS-Sac-1443Saccharomyces cerevisiae42.312e-73 238
LLPS-Mao-0807Magnaporthe oryzae42.246e-75 242
LLPS-Fuv-0769Fusarium verticillioides42.182e-78 251
LLPS-Fuo-1075Fusarium oxysporum42.181e-78 251
LLPS-Ast-1248Aspergillus terreus42.014e-71 232
LLPS-Gas-1135Galdieria sulphuraria41.944e-57 197
LLPS-Tru-0338Triticum urartu41.843e-50 176
LLPS-Lem-1487Leptosphaeria maculans41.694e-68 226
LLPS-Mel-0790Melampsora laricipopulina41.571e-73 241
LLPS-Chc-1069Chondrus crispus41.561e-1063.2
LLPS-Asn-1263Aspergillus nidulans41.333e-75 243
LLPS-Brd-1331Brachypodium distachyon41.164e-53 186
LLPS-Asfu-0779Aspergillus fumigatus41.044e-76 245
LLPS-Scc-1378Schizosaccharomyces cryophilus40.992e-73 238
LLPS-Asc-0393Aspergillus clavatus40.942e-74 240
LLPS-Yal-1191Yarrowia lipolytica40.839e-75 241
LLPS-Hov-2166Hordeum vulgare40.792e-52 184
LLPS-Asg-0816Ashbya gossypii40.718e-74 238
LLPS-Pyt-0583Pyrenophora teres40.683e-69 229
LLPS-Pytr-1547Pyrenophora triticirepentis40.681e-69 229
LLPS-Orbr-0856Oryza brachyantha40.534e-44 159
LLPS-Tra-0164Triticum aestivum40.432e-53 186
LLPS-Chr-1599Chlamydomonas reinhardtii40.212e-55 191
LLPS-Amt-0563Amborella trichopoda40.141e-52 186
LLPS-Cog-0444Colletotrichum gloeosporioides40.08e-61 204
LLPS-Phn-0880Phaeosphaeria nodorum39.941e-70 233
LLPS-Cym-0322Cyanidioschyzon merolae39.795e-47 171
LLPS-Put-1278Puccinia triticina39.621e-68 229
LLPS-Lep-1792Leersia perrieri39.595e-52 183
LLPS-Ori-2365Oryza indica39.515e-52 182
LLPS-Org-0884Oryza glaberrima39.514e-52 182
LLPS-Ors-1853Oryza sativa39.514e-52 182
LLPS-Thc-1772Theobroma cacao39.421e-42 157
LLPS-Pug-1063Puccinia graminis39.32e-67 226
LLPS-Sem-1618Selaginella moellendorffii39.191e-53 187
LLPS-Sob-1545Sorghum bicolor38.855e-48 171
LLPS-Brn-0622Brassica napus38.649e-51 180
LLPS-Zem-1498Zea mays38.515e-46 168
LLPS-Phv-0417Phaseolus vulgaris38.492e-48 172
LLPS-Sot-1287Solanum tuberosum38.414e-54 188
LLPS-Mua-1403Musa acuminata38.318e-52 183
LLPS-Orm-1722Oryza meridionalis38.313e-50 178
LLPS-Bro-3039Brassica oleracea38.315e-51 180
LLPS-Orp-0476Oryza punctata38.312e-50 179
LLPS-Brr-2178Brassica rapa38.318e-51 180
LLPS-Art-0727Arabidopsis thaliana38.312e-49 176
LLPS-Osl-0716Ostreococcus lucimarinus38.083e-56 192
LLPS-Nia-1836Nicotiana attenuata38.089e-53 185
LLPS-Arl-2441Arabidopsis lyrata37.991e-49 177
LLPS-Orgl-0854Oryza glumaepatula37.977e-50 177
LLPS-Orb-1353Oryza barthii37.977e-50 177
LLPS-Orni-1645Oryza nivara37.977e-50 177
LLPS-Orr-0772Oryza rufipogon37.978e-50 177
LLPS-Prp-0287Prunus persica37.923e-52 184
LLPS-Dac-0744Daucus carota37.851e-48 174
LLPS-Glm-2907Glycine max37.766e-50 177
LLPS-Gor-1063Gossypium raimondii37.761e-43 160
LLPS-Sol-1058Solanum lycopersicum37.759e-53 185
LLPS-Cus-0970Cucumis sativus37.661e-44 163
LLPS-Mae-1627Manihot esculenta37.661e-50 180
LLPS-Vir-2118Vigna radiata37.464e-49 176
LLPS-Php-1614Physcomitrella patens37.461e-51 182
LLPS-Met-2608Medicago truncatula37.221e-50 179
LLPS-Viv-0790Vitis vinifera37.132e-50 177
LLPS-Hea-1303Helianthus annuus36.895e-50 177
LLPS-Coc-1991Corchorus capsularis36.721e-41 155
LLPS-Sei-2443Setaria italica36.497e-47 169
LLPS-Via-2292Vigna angularis36.362e-47 170
LLPS-Pot-1975Populus trichocarpa36.162e-48 173